Health effects of cArdiac fluoRoscopy and MOderN radIotherapy in paediatriCs

Informations projet

HARMONIC

N° de convention de subvention: 847707

DOI

10.3030/847707

Projet clôturé

Date de signature de la CE 13 Mai 2019

Date de début 1 Juin 2019

Date de fin 30 Novembre 2024

Financé au titre de

• Euratom

Coût total

€ 6 999 988,75

Contribution de l’UE

€ 6 999 988,75

Coordonné par

FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA
Spain

CORDIS fournit des liens vers les livrables publics et les publications des projets HORIZON.

Les liens vers les livrables et les publications des projets du 7e PC, ainsi que les liens vers certains types de résultats spécifiques tels que les jeux de données et les logiciels, sont récupérés dynamiquement sur OpenAIRE .

Livrables

Open Research Data Pilot (1)

Data management plan

Websites, patent fillings, videos etc. (7)

Policy Brief - impact and implications

Policy Brief impact and implications

Factsheet and/or interactive infographic
Website and Project brochure
Newsletter 1
Newsletter 2
Logo
Newsletter 3

Documents, reports (1)

Guidelines for reducing exposure to ionising radiations from imaging studies on paediatric patients

Publications

Peer reviewed articles (23)

Delineation atlas of the Circle of Willis and the large intracranial arteries for evaluation of doses to neurovascular structures in pediatric brain tumor patients treated with radiation therapy

Auteurs: L. Toussaint, S. Peters, R. Mikkelsen, S. Karabegovic, C. Bäumer, L. P. Muren, L. Tram-Henriksen, M. Høyer, Y. Lassen-Ramshad & B. Timmermann
Publié dans: Acta Oncologica, 2021, ISSN 0284-186X
Éditeur: Taylor & Francis
DOI: 10.1080/0284186x.2021.1945679

Health effects of ionising radiation in paediatrics undergoing either cardiac fluoroscopy or modern radiotherapy (The HARMONIC project)

Auteurs: Isabelle Thierry-Chef; Beate Timmermann; Neige Journy; Marie-Odile Bernier; Richard McNally; Jérémie Dabin; Lorenzo Brualla; Siamak Haghdoost; Adelaida Sarukhan; Karin Haustermans; Inge De Wit; Sofie Isebaert; Yasmin Lassen-Ramshad; Louise Tram Henriksen; Morten Høyer; Laura Toussaint; Guillaume Boissonnat; Juliette Thariat; Charlotte Demoor-Goldschmidt; Nadia Haddy; Stéphanie Bolle; Brice Fre
Publié dans: EPJ Nuclear Sci. Technol, Numéro 5, 2023, ISSN 2491-9292
Éditeur: EDP Science
DOI: 10.1051/epjn/2023009

A Longitudinal Study of Individual Radiation Responses in Pediatric Patients Treated with Proton and Photon Radiotherapy, and Interventional Cardiology: Rationale and Research Protocol of the HARMONIC Project

Auteurs: Maria Grazia Andreassi,Nadia Haddy,Mats Harms-Ringdahl,Jonica Campolo,Andrea Borghini, François Chevalier, Jochen M. Schwenk, Brice Fresneau, Stephanie Bolle, Manuel Fuentes and Siamak Haghdoost
Publié dans: International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms24098416

Neutron dose and its measurement in proton therapy – Current State of Knowledge

Auteurs: Hälg, Roger Antoine; Schneider, Uwe
Publié dans: British Journal of Radiology, Numéro 4, 2020, ISSN 0007-1285
Éditeur: British Institute of Radiology
DOI: 10.5167/uzh-181386

The HARMONIC project: Study design for assessment of cancer risks following cardiac fluoroscopy in childhood

Auteurs: Richard W Harbron, Isabelle Thierry-Chef, Mark S Pearce, Marie Odile Bernier, Serge Dreuil, Estelle Rage, Maria Grazia Andreassi, Eugenio Picano, Steffen Dreger, Hajo Zeeb, Hilde Olerud, Utheya Thevathas, Kristina Kjaerheim, Gaute Døhlen, Andreas Jahnen, Johannes Hermen, Vadim Chumak, Elena Bakhanova, Vitalii Voloskyi, David Borrego, Choonsik Lee, Jérémie Dabin
Publié dans: Journal of Radiological Protection, 2020, ISSN 0952-4746
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1361-6498/aba66d

The burden of radiation exposure in congenital heart disease: the Italian cohort profile and bioresource collection in HARMONIC project

Auteurs: Jonica Campolo, Giuseppe Annoni, Gabriele Vignati, Alessio Peretti, Marco Papa, Paola Enrica Colombo, Gaia Muti, Marina Parolini, Andrea Borghini, Marzia Giaccardi, Lamia Ait-Alì, Eugenio Picano, Maria Grazia Andreassi
Publié dans: Italian Journal of Pediatrics, Numéro 50, 2024, ISSN 1824-7288
Éditeur: BMC
DOI: 10.1186/s13052-024-01663-4

Monte Carlo simulation of conical collimators for stereotactic radiosurgery with a 6 MV flattening-filter-free photon beam.

Auteurs: M. Hermida-López; David Sánchez-Artuñedo; Miguel Rodriguez; Lorenzo Brualla
Publié dans: Medical Physics, Numéro 5, 2021, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.14837

Use of ionizing radiation in a Norwegian cohort of children with congenital heart disease: imaging frequency and radiation dose for the Health Effects of Cardiac Fluoroscopy and Modern Radiotherapy in Pediatrics (HARMONIC) study

Auteurs: Susmita Afroz, Bjørn H. Østerås, Utheya S. Thevathas, Gaute Dohlen, Caroline Stokke, Trude E. Robsahm & Hilde M. Olerud
Publié dans: Pediatric Radiology, 2023, ISSN 0301-0449
Éditeur: Springer Verlag
DOI: 10.1007/s00247-023-05774-8

Cumulative radiation dose in children with congenital heart disease: national data 2000–2021, stratified by diagnosis, age, and imaging modality

Auteurs: Susmita Afroz, Bjørn H Østerås, Utheya S Thevathas, Lise Heiberg, Trude E Robsahm, Hilde M Olerud, Gaute Dohlen
Publié dans: Acta Radiologica, 2025, ISSN 0284-1851
Éditeur: Taylor & Francis
DOI: 10.1177/02841851251327896

Consistency of Faraday cup and ionization chamber dosimetry of proton fields and the role of nuclear interactions

Auteurs: Jörg Wulff, Anne Paul, Claus Maximilian Bäcker, Kilian-Simon Baumann, Johannes Niklas Esser, Benjamin Koska, Beate Timmermann, Nico Gerd Verbeek, Christian Bäumer
Publié dans: Medical Physics, 2023, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.16819

Experiments and Monte Carlo simulations on multiple Coulomb scattering of protons

Auteurs: Verbeek, Nico; Wulff, Jörg; Janson, Martin; Bäumer, Christian; Timmermann, Beate; Brualla, Lorenzo
Publié dans: Medical Physics, Numéro 2, 2021, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.14860

Monte Carlo Computation of Dose-Volume Histograms in Structures at Risk of an Eye Irradiated with Heterogeneous Ruthenium-106 Plaques

Auteurs: Francisco J. Zaragoza, Marion Eichmann, Dirk Flühs, Beate Timmermann, Lorenzo Brualla
Publié dans: Ocular Oncology and Pathology, Numéro 6/5, 2020, Page(s) 353-359, ISSN 2296-4681
Éditeur: Karger
DOI: 10.1159/000508113

Complete patient exposure during paediatric brain cancer treatment for photon and proton therapy techniques including imaging procedures

Auteurs: Marijke De Saint-Hubert, Guillaume Boissonnat, Uwe Schneider, Christian Bäumer, Nico Verbeek, Johannes Esser, Jörg Wulff, Florian Stuckmann, Finja Suesselbeck, Racell Nabha, Jérémie Dabin, Fabiano Vasi, Stephan Radonic, Miguel Rodriguez, Anne Catherine Simon, Neige Journy, Beate Timmermann, Isabelle Thierry-Chef, Lorenzo Brualla
Publié dans: Frontiers in oncology, 2023, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2023.1222800

Validation of a Monte Carlo Framework for Out-of-Field Dose Calculations in Proton Therapy

Auteurs: De Saint-Hubert, Marijke; Verbeek, Nico; Bäumer, Christian; Esser, Johannes; Wulff, Jörg; Nabha, Racell; Van Hoey, Olivier; Dabin, Jérémie; Stuckmann, Florian; Vasi, Fabiano; Radonic, Stephan; Boissonnat, Guillaume; Schneider, Uwe; Rodriguez, Miguel; Timmermann, Beate; Thierry-Chef, Isabelle; Brualla, Lorenzo
Publié dans: Frontiers in oncology, Numéro 1, 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.882489

Experimental Validation of an Analytical Program and a Monte Carlo Simulation for the Computation of the Far Out-of-Field Dose in External Beam Photon Therapy Applied to Pediatric Patients

Auteurs: De Saint-Hubert, Marijke; Suesselbeck, Finja; Vasi, Fabiano; Stuckmann, Florian; Rodriguez, Miguel; Dabin, Jérémie; Timmermann, Beate; Thierry-Chef, Isabelle; Schneider, Uwe; Brualla, Lorenzo
Publié dans: Frontiers in oncology, Numéro 3, 2022, ISSN 2234-943X
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fonc.2022.882506

Single pencil beam benchmark of a module for Monte Carlo simulation of proton transport in the PENELOPE code

Auteurs: Nico Verbeek, Jörg Wulff, Christian Bäumer, Sabrina Smyczek, Beate Timmermann, Lorenzo Brualla
Publié dans: Medical Physics, 2020, ISSN 0094-2405
Éditeur: American Association of Physicists in Medicine
DOI: 10.1002/mp.14598

Medical applications of ionizing radiation and radiation protection for European patients, population and environment

Auteurs: Thierry-Chef, Isabelle; Cardis, Elisabeth; Damilakis, John; Frija, Guy; Hierath, Monika; Hoeschen, Christop; EURAMED ROCC-N-ROLL consortia members
Publié dans: EPJ Nuclear Sci. Technol, Numéro 5, 2022, ISSN 2491-9292
Éditeur: EDP Sciences, Springer
DOI: 10.1051/epjn/2022044

Development of whole-body representation and dose calculation in a commercial treatment planning system

Auteurs: Pascal Hauri , Stephan Radonic , Fabiano Vasi , Marina Ernst , Marcin Sumila , Matthew M Mille, Choonsik Lee , Matthias Hartmann , Uwe Schneider
Publié dans: Zeitschrift für Medizinische Physik, 2022, ISSN 0939-3889
Éditeur: Urban & Fischer Verlag
DOI: 10.1016/j.zemedi.2021.05.001

Monte Carlo simulation of the Varian TrueBeam flattened‑filtered beams using a surrogate geometry in PRIMO

Auteurs: Miguel Rodriguez, Josep Sempau & Lorenzo Brualla
Publié dans: Radiation Oncology, 2024, ISSN 1748-717X
Éditeur: BioMed Central
DOI: 10.1186/s13014-024-02405-w

Monte Carlo verification of the holder correction factors for the radiophotoluminescent glass dosimeter used by the IAEA in international dosimetry audits

Auteurs: Josep Sempau; P. Kazantsev; Joanna Izewska; Lorenzo Brualla
Publié dans: Physica Medica, Numéro 7, 2021, ISSN 1120-1797
Éditeur: Istituti Editoriali e Poligrafici Internazionali
DOI: 10.1016/j.ejmp.2021.04.014

Assessing late outcomes of advances in radiotherapy for paediatric cancers: study protocol of the “HARMONIC-RT” European registry (NCT 04746729)

Auteurs: Neige Journy, Stéphanie Bolle, Lorenzo Brualla, Agnès Dumas, Brice Fresneau, Nadia Haddy, Siamak Haghdoost, Karin Haustermans, Angela Jackson, Sanja Karabegovic, Yasmin Lassen-Ramshad, Juliette Thariat, Martina Roxanne Wette, Suzan Botzenhardt, Inge De Wit, Charlotte Demoor-Goldschmidt, Melissa Christiaens, Morten Høyer, Sofie Isebaert, Sandra Jacobs, Louise Tram Henriksen, John H Maduro, Cecil
Publié dans: Radiother Oncol, 2023, ISSN 0167-8140
Éditeur: Elsevier BV
DOI: 10.1016/j.radonc.2023.109972

European practice on neurovascular late effects after pediatric radiotherapy: considerations on dose planning and follow-up – a HARMONIC/SIOPE ROWG survey

Auteurs: Laura Toussaint, Louise Tram Henriksen, Karen Van Beek, Stephanie Bolle, Charlotte Demoor-Goldschmidt, Jenny Gains, Morten Høyer, Geert O. Janssens, Rolf-Dieter Kortmann, Catia Martins Pedro, Beate Timmermann, Katrin Scheinemann, Yasmin Lassen-Ramshad
Publié dans: Acta Oncologica, Numéro 64, 2025, Page(s) 703-707, ISSN 1651-226X
Éditeur: MJS Publishing, Medical Journals Sweden AB
DOI: 10.2340/1651-226x.2025.43028

Doses from ionising radiation in paediatric cardiac catheterisations in Norway 1975–2021

Auteurs: S Afroz, B H Østerås, Thevethas U S, M Meo, A Jahnen, J Dabin, I Thierry-Chef, T E Robsahm, G Døhlen, H M Olerud
Publié dans: Journal of Radiological Protection, Numéro 44, 2024, Page(s) 041513, ISSN 0952-4746
Éditeur: Institute of Physics Publishing
DOI: 10.1088/1361-6498/ad958e

Conference proceedings (1)

Dose reconstruction for pediatric cardiac catheterizations in the 1980s – an input to the epidemiological study HARMONIC

Auteurs: H. M. Olerud, U. S. Thevathas, K. Kjærheim, G. Døhlen
Publié dans: Electronic Presentation Online System (EPOS), 2022
Éditeur: ESR - European Society of Radiology
DOI: 10.26044/ecr2022/c-15236