Repurposing clinically approved antibacterial drugs for treponematoses therapy

Project Information

Trep-AB

Grant agreement ID: 850450

DOI

10.3030/850450

Project closed

EC signature date 29 January 2020

Start date 1 February 2020

End date 31 January 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 498 790,00

EU contribution

€ 1 498 790,00

Coordinated by

FUNDACION FLS DE LUCHA CONTRA ELSIDA LAS ENFERMEDADES INFECCIOSASY LA PROMOCION DE LA SALUD Y LACIENCIA
Spain

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Oral linezolid compared with benzathine penicillin G for treatment of early syphilis in adults (Trep-AB Study) in Spain: a prospective, open-label, non-inferiority, randomised controlled trial

Author(s): Maria Ubals, Patricia Nadal-Baron, Maider Arando, Ángel Rivero, Adrià Mendoza, Vicent Descalzo Jorro, Dan Ouchi, Clara Pérez-Mañá, Marlene Álvarez, Andrea Alemany, Yannick Hoyos-Mallecot, Ethan Nunley, Nicole A P Lieberman, Alexander L Greninger, Cristina Galván-Casas, Clara Suñer, Camila G-Beiras, Roger Paredes, Alicia Rodríguez-Gascón, Andrés Canut, Vicente García-Patos, Magí Farré
Published in: The Lancet Infectious Diseases, Issue 24, 2024, Page(s) 404-416, ISSN 1473-3099
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1473-3099(23)00683-7

Efficacy of linezolid on Treponema pallidum, the syphilis agent: A preclinical study

Author(s): A.M. Haynes, L. Giacani, M. Vall-Mayans, M. Ubals, C. Nieto, C. Pérez-Mañá, Ll. Quintó, E. Romeis, O. Mitjà
Published in: eBiomedicine, Issue 23523964, 2021, ISSN 2352-3964
Publisher: Elsevier BV
DOI: 10.1016/j.ebiom.2021.103281

Treatment of bacterial sexually transmitted infections in Europe: gonorrhoea, Mycoplasma genitalium, and syphilis

Author(s): Oriol Mitjà, Clara Suñer, Lorenzo Giacani, Martí Vall-Mayans, George-Sorin Tiplica, Jonathan D.C. Ross, Catriona S. Bradshaw
Published in: The Lancet Regional Health - Europe, Issue 34, 2023, Page(s) 100737, ISSN 2666-7762
Publisher: Elsevier
DOI: 10.1016/j.lanepe.2023.100737

Rapid Serologic Test for Diagnosis of Yaws in Patients with Suspicious Skin Ulcers

Author(s): Clara Suñer, Lucy N. John, Wendy Houinei, Maria Ubals, Dan Ouchi, Andrea Alemany, Cristina Galván-Casas, Michael Marks, Oriol Mitjà, Martí Vall, Camila G. Beiras
Published in: Emerging Infectious Diseases, Issue 29, 2023, ISSN 1080-6040
Publisher: US National Center for Infectious Diseases
DOI: 10.3201/eid2908.230608

Antimicrobial susceptibility of Treponema pallidum subspecies pallidum: an in-vitro study

Author(s): Lauren C Tantalo, Nicole A P Lieberman, Clara Pérez-Mañá, Clara Suñer, Marti Vall Mayans, Maria Ubals, Camila González-Beiras, Alicia Rodríguez-Gascón, Andrés Canut, Fernando González-Candelas, John Mueller, Kenneth Tapia, Alexander L Greninger, Lorenzo Giacani, Oriol Mitjà
Published in: The Lancet Microbe, Issue 4, 2023, Page(s) e994-e1004, ISSN 2666-5247
Publisher: The Lancet
DOI: 10.1016/s2666-5247(23)00219-7

Epidemiology and determinants of reemerging bacterial sexually transmitted infections (STIs) and emerging STIs in Europe

Author(s): Oriol Mitjà, Valeska Padovese, Cinta Folch, Isotta Rossoni, Michael Marks, Miquel Angel Rodríguez i Arias, Amalio Telenti, Angela Ciuffi, Karel Blondeel, Otilia Mårdh, Jordi Casabona
Published in: The Lancet Regional Health - Europe, Issue 34, 2023, Page(s) 100742, ISSN 2666-7762
Publisher: Elsevier
DOI: 10.1016/j.lanepe.2023.100742