Project description
Innovative solution for early disease diagnosis
Early diagnosis of certain diseases relies on ultra-high–field scanners that provide images with better spatial or temporal resolutions. However, several limitations prevent the clinical application of this equipment. The heterogeneous excitation of the nuclear spins leads to shadows or contrast losses across the human brain images at 7 Tesla (T) and abdomen images at 3T. The EU-funded MRI PADS project will bring to the market a solution developed during the FET Open M-CUBE project. This initiative will demonstrate an industrial process for the elaboration of prototype safety tests such as temperature monitoring, specific absorption rate and leaking tests to demonstrate that they are safe for clinical use.
Objective
From research centers like CEA-Neurospin in France who recently acquired a 11.7T scanner to hospitals such as Saint Thomas in UK who acquired the latest commercial 7T scanner from Siemens, healthcare has taken a tremendous leap forward those last years. Indeed, ultra-high field scanners provide images with better spatial and/or temporal resolutions that are used for early diagnosis of disease and therefore enhance their treatments. However, several limitations have been reported, hindering clinical application of these devices. At such field strengths, one of the main issues is the heterogeneous excitation of the nuclear spins. Typically, it leads to shadows or contrast losses across the human brain images at 7T but also abdomen images at 3T. Those scanners still account for around 30% of the market in 2013. To tackle this issue, several solutions are under development but due to their complexity, it will require several years before their integration into clinical routines. This is even more so given the fact that most of those solutions are active: a careful monitoring of the energy absorbed by the human body which increases exponentially with the initial field is required so it remains below safety limitations. Therefore, there is right now an unfulfilled need of a simple and effective solution for all the 3T active scanners and also for the growing market of 7T scanners. It will greatly benefit clinical imaging applications but first need to be labelled as a CE medical device (MD). The current project objective is to bring to the market a side solution developed during the FET-OPEN project Mcube. First, an industrial process for the elaboration is studied and validated. Then, elaborated prototypes safety tests such as temperature monitoring, specific absorption rate or leaking tests are carried out to prove they are safe for clinical use. Finally, their performance are evaluated on phantoms as well as on volunteers.
Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
MAIN PROGRAMME
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H2020-EU.1.2.1. - FET Open
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
CSA - Coordination and support action
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-FETOPEN-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1228 PLAN-LES-OUATES
Switzerland
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.