A synthetic library of DNA regulatory sites could help control gene expression
All somatic cells in an organism contain the entire genetic code for all the proteins the organism makes. However, gene expression in cells is highly regulated by repressor or activator proteins that bind to DNA, often close to the start site of transcription. Given the critical role of gene expression in normal development and functioning and in disease, the EU-funded UNILIB project has developed a new tool to study and manipulate it better. A synthetic library of DNA patterns representing regulatory binding sites conserved in organisms from yeast to mammals could unlock gene expression in a myriad of applications. UNILIB plans to demonstrate its capabilities and pave the way for maximum impact.
Fields of science
Call for proposalSee other projects for this call
Funding SchemeCSA - Coordination and support action
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