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Universal regulatory library for any cell type

Project description

A synthetic library of DNA regulatory sites could help control gene expression

All somatic cells in an organism contain the entire genetic code for all the proteins the organism makes. However, gene expression in cells is highly regulated by repressor or activator proteins that bind to DNA, often close to the start site of transcription. Given the critical role of gene expression in normal development and functioning and in disease, the EU-funded UNILIB project has developed a new tool to study and manipulate it better. A synthetic library of DNA patterns representing regulatory binding sites conserved in organisms from yeast to mammals could unlock gene expression in a myriad of applications. UNILIB plans to demonstrate its capabilities and pave the way for maximum impact.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-03

Coordinator

TECHNION - ISRAEL INSTITUTE OF TECHNOLOGY
Net EU contribution
€ 67 500,00
Address
Senate Building Technion City
32000 Haifa
Israel

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (1)

REICHMAN UNIVERSITY
Israel
Net EU contribution
€ 32 500,00
Address
8 Hauniversita St
4610101 Herzliya

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00