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A synthetic biology approach for T cell exhaustion

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

A call for caution in analysing mammalian co-transfection experiments and implications of resource competition in data misinterpretation.

Author(s): Di Blasi R, Marbiah M, Siciliano V, Polizzi K, Ceroni F
Published in: Nature Communications, Issue 20411723, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-22795-9

Characterization and mitigation of gene expression burden in mammalian cells

Author(s): Timothy Frei, Federica Cella, Fabiana Tedeschi, Joaquín Gutiérrez, Guy-Bart Stan, Mustafa Khammash, Velia Siciliano
Published in: Nature Communications, Issue 11/1, 2020, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-020-18392-x

gDesigner: computational design of synthetic gRNAs for Cas12a-based transcriptional repression in mammalian cells

Author(s): Crone M, Mac Donald J, Freemont P, Siciliano V.
Published in: NPJ Systems Biology and Applications, Issue 20567189, 2022, ISSN 2056-7189
Publisher: Nature publishing group
DOI: 10.1038/s41540-022-00241-w

MIRELLA: a mathematical model explains the effect of microRNA-mediated synthetic genes regulation on intracellular resource allocation

Author(s): Federica Cella, Giansimone Perrino, Fabiana Tedeschi, Gabriella Viero, Carla Bosia, Guy-Bart Stan, Velia Siciliano
Published in: Nucleic Acids Research, Issue 51, 2023, Page(s) 3452-3464, ISSN 0305-1048
Publisher: Oxford University Press
DOI: 10.1093/nar/gkad151

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