This project has allowed LUMICKS to develop a prototype and explore the market potential for a new label free imaging modality for the C-Trap optical tweezers platform. The power of the technology was demonstrated using live cell imaging and preliminary single molecule experiments. LUMICKS will continue developments to push sensitivity and imaging speed before introducing the modality on the C-Trap platform. Currently LUMICKS C-Trap technology enables researchers to manipulate and image single molecules using a combination of optical tweezers and fluorescence microscopy. The need to fluorescently label molecules before imaging can be challenging and potentially even interfere with the molecular interactions under scrutiny. Furthermore, single molecule fluorescence techniques come with a few intrinsic drawbacks (e.g. the need for labelling steps, limited signal due to photobleaching, limited photon flux which limits imaging speed). Successful application of this new label free microscopy method in academic and pharmaceutical research will have profound impact on the understanding of key biological processes and optimization of drug discovery. The objectives of the project are mapping of the market requirements for a successful product, the development of a label free imaging module for the LUMICKS C-Trap product and the development of marketing materials and a sales strategy.