Project description
Biological structures come into clear view without the need for labeling
Cell imaging techniques have advanced tremendously over the last few decades, providing high-resolution real-time information about numerous biological processes. One important way scientists have been able to capture processes that have occurred or tag molecules of interest is with the use of fluorescent labels. However, that technique can add time, money and obviously a modification to native molecules and structures. The EU-funded LABELFREE project is preparing to put its phi-SCAT system for label-free high-contrast imaging on the market as a valuable alternative for many applications. The commercialisation plan includes making it available as a stand-alone system and potentially integrated into existing microscope systems for maximum impact and flexibility.
Objective
We will launch phi-SCAT, a novel imaging technology, which uniquely allows for label-free imaging of biological structures of interest. We will do this by productizing the interferometric scattering technology that was invented in course of the Chromavision FET-OPEN project. Proof-of-concept data has been obtained in the FET-OPEN project, and proved the technology’s value, complementary to existing imaging methods that are either low contrast or depend on fluorescent labels. The project will focus on the steps needed for the market launch of this novel technology. We will follow two parallel trajectories for exploitation: firstly we will implement and launch a phi-SCAT module on our existing C-Trap single-molecule analysis product line. Secondly we will approach potential licensing partners for implementation of the phi-SCAT technology on existing microscope platforms.
This project will result in a valuable valorisation of one of the most significant innovations that stemmed from the Chromavision FET-OPEN project. Besides significant positive impact on our C-Trap product line’s turnover and gross margin, the application of this more effective microscopy method in academic and pharmaceutical research will have profound impact on the understanding of key biological processes and contribute greatly to optimization of the drug discovery process
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- medical and health sciences basic medicine pharmacology and pharmacy drug discovery
- natural sciences physical sciences optics microscopy
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Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.2. - EXCELLENT SCIENCE - Future and Emerging Technologies (FET)
MAIN PROGRAMME
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H2020-EU.1.2.1. - FET Open
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
CSA - Coordination and support action
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) H2020-FETOPEN-2018-2020
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
1105 AG Amsterdam
Netherlands
The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.