Early recognition of intracranial aneurysms to PRevent aneurYSMal subarachnoid hemorrhage

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Data Management Plan (DMP)

Data Management Plan DMP

Publications

Drug classes affecting intracranial aneurysm risk: Genetic correlation and Mendelian randomization

Author(s): Ynte M Ruigrok, Jan H Veldink, Mark K Bakker
Published in: European Stroke Journal, Issue 9, 2024, Page(s) 687-695, ISSN 2396-9873
Publisher: SAGE
DOI: 10.1177/23969873241234134

Genetic Insights Into Hemorrhagic Stroke and Vascular Malformations: Pathogenesis and Emerging Therapeutic Strategies

Author(s): Pazhanichamy Kalailingam, Kristiina Rannikmae, Moran Hausman-Kedem, Patricia L. Musolino, Ynte M. Ruigrok
Published in: Stroke, 2025, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.124.045182

Anatomical Markers Associated With the Presence of Intracranial Aneurysms in Individuals Screened for Aneurysms

Author(s): Iris N. Vos, Rick J. van Tuijl, Liselore A. Mensing, Maud E. H. Ophelders, Mireille R. E. Velthuis, Nicolaas P. A. Zuithoff, Gabriel J. E. Rinkel, Hugo J. Kuijf, Jaco J. M. Zwanenburg, Irene C. van der Schaaf, Birgitta K. Velthuis, Ynte M. Ruigrok
Published in: Stroke: Vascular and Interventional Neurology, Issue 4, 2024, ISSN 2694-5746
Publisher: Wiley
DOI: 10.1161/svin.124.001299

Sex Hormones and Risk of Aneurysmal Subarachnoid Hemorrhage: A Mendelian Randomization Study

Author(s): Rob Molenberg, Chris H.L. Thio, Marlien W. Aalbers, Maarten Uyttenboogaart, ISGC Intracranial Aneurysm Working Group*, Susanna C. Larsson, Mark K. Bakker, Ynte M. Ruigrok, Harold Snieder and J. Marc C. van Dijk
Published in: Stroke, 2022, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.121.038035

Genome-wide linkage analysis combined with genome sequencing in large families with intracranial aneurysms

Author(s): Mark K Bakker, Suze Cobyte, Frederic A M Hennekam, Gabriel J E Rinkel, Jan H Veldink, Ynte M Ruigrok
Published in: Eur J Hum Genet, 2022, ISSN 1018-4813
Publisher: Natue Publishing Group
DOI: 10.1038/s41431-022-01059-0

Intracranial arterial calcification in patients with unruptured and ruptured intracranial aneurysms

Author(s): Maarten J. Kamphuis, Laura T. van der Kamp, Edwin Lette, Gabriel J. E. Rinkel, Mervyn D. I. Vergouwen, Irene C. van der Schaaf, Pim A. de Jong, Ynte M. Ruigrok
Published in: European Radiology, Issue 34, 2024, Page(s) 7517-7525, ISSN 1432-1084
Publisher: Springer
DOI: 10.1007/s00330-024-10789-2

Geometric Deep Learning Using Vascular Surface Meshes for Modality-Independent Unruptured Intracranial Aneurysm Detection

Author(s): Kimberley M. Timmins, Irene C. van der Schaaf, Iris N. Vos, Ynte M. Ruigrok, Birgitta K. Velthuis, Hugo J. Kuijf
Published in: IEEE Transactions on Medical Imaging, Issue 42, 2023, Page(s) 3451-3460, ISSN 0278-0062
Publisher: Institute of Electrical and Electronics Engineers
DOI: 10.1109/tmi.2023.3288746

Relationship between diameter asymmetry and blood flow in the pre-communicating (A1) segment of the anterior cerebral arteries

Author(s): van Tuijl RJ, Ruigrok YM, Ophelders M, Vos IN, van der Schaaf IC, Zwanenburg J, Velthuis BK.
Published in: J Neuroradiol ., Issue 50, 2023, Page(s) 402-406, ISSN 1773-0406
Publisher: Elsevier
DOI: 10.1016/j.neurad.2022.10.004

Role of Rare Genetic Variants Found in Families With Intracranial Aneurysms in the General Dutch and UK Population

Author(s): Mark K. Bakker, Roos A. Ettema, Maxime Klostermann, Gabriël J.E. Rinkel, Jan H. Veldink, Ynte M. Ruigrok
Published in: Stroke, Issue 52, 2024, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.121.035492

Identifying novel risk factors for aneurysmal subarachnoid haemorrhage using machine learning

Author(s): Jos P. Kanning, Junfeng Wang, Shahab Abtahi, Mirjam I. Geerlings & Ynte M. Ruigrok
Published in: Scientific Reports, Issue 15, Article number: 9256, 2025, ISSN 2045-2322
Publisher: Nature Publishing Group

Sex Difference and Rupture Rate of Intracranial Aneurysms: An Individual Patient Data Meta-Analysis

Author(s): Charlotte C.M. Zuurbier, Rob Molenberg, Liselore A. Mensing, Marieke J.H. Wermer, Seppo Juvela, Antti E. Lindgren, Juha E. Jääskeläinen, Timo Koivisto, Tomosato Yamazaki, Maarten Uyttenboogaart, J. Marc C. van Dijk, Marlien W. Aalbers, Akio Morita, Shinjiro Tominari, Hajime Arai, Kazuhiko Nozaki, Yuichi Murayama, Toshihiro Ishibashi, Hiroyuki Takao, Renato Gondar, Philippe Bijlenga, Gabriel J.E
Published in: Stroke, Issue 53, 2024, Page(s) 362-369, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.121.035187

Difference in Rupture Risk Between Familial and Sporadic Intracranial Aneurysms

Author(s): Charlotte C.M. Zuurbier, Liselore A. Mensing, Marieke J.H. Wermer, Seppo Juvela, Antti E. Lindgren, Timo Koivisto, Juha E. Jääskeläinen, Tomosato Yamazaki, Rob Molenberg, J. Marc C. van Dijk, Maarten Uyttenboogaart, Marlien Aalbers, Akio Morita, Shinjiro Tominari, Hajime Arai, Kazuhiko Nozaki, Yuichi Murayama, Toshihiro Ishibashi, Hiroyuki Takao, Gabriel J.E. Rinkel, Jacoba P. Greving, Ynte M.
Published in: Neurology, Issue 97, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000012885

Graph convolutional networks for automated intracranial artery labeling

Author(s): Iris N. Vos, Ynte M. Ruigrok, Ishaan R. Bhat, Kimberley M. Timmins, Birgitta K. Velthuis, Hugo J. Kuijf
Published in: Journal of Medical Imaging, Issue 11, 2024, ISSN 2329-4302
Publisher: SPIE
DOI: 10.1117/1.jmi.11.1.014007

Relationship between 3D Morphologic Change and 2D and 3D Growth of Unruptured Intracranial Aneurysms

Author(s): K.M. Timmins; H.J. Kuijf; M.D.I. Vergouwen; Y.M. Ruigrok; B.K. Velthuis; I.C. van der Schaaf
Published in: AJNR Am J Neuroradiol, Issue 3, 2021, ISSN 0195-6108
Publisher: American Society of Neuoradiology
DOI: 10.3174/ajnr.a7418

Hemodynamic Parameters in the Parent Arteries of Unruptured Intracranial Aneurysms Depend on Aneurysm Size and Are Different Compared to Contralateral Arteries: A 7 Tesla <scp>4D</scp> Flow <scp>MRI</scp> Study

Author(s): Rick J. van Tuijl, Kimberley M. Timmins, Birgitta K. Velthuis, Pim van Ooij, Jaco J.M. Zwanenburg, Ynte M. Ruigrok, Irene C. van der Schaaf
Published in: Journal of Magnetic Resonance Imaging, Issue 59, 2023, Page(s) 223-230, ISSN 1053-1807
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/jmri.28756

Genetic variation in NFE2L2 is associated with outcome following aneurysmal subarachnoid haemorrhage.

Author(s): Ben Gaastra; Poppy Duncan; Mark K. Bakker; Isabel C. Hostettler; Varinder S. Alg; Henry Houlden; Ynte M. Ruigrok; Ian Galea; Will Tapper; David Werring; Diederik Bulters
Published in: European journal of neurology., Issue 1, 2022, ISSN 1468-1331
Publisher: Wiley Online Library
DOI: 10.1111/ene.15571

Imaging markers of intracranial aneurysm development: A systematic review

Author(s): Angelina K Kancheva, Birgitta K. Velthuis, Ynte M.Ruigrok
Published in: Journal of Neuroradiology, Issue 01509861, 2022, Page(s) 219-224, ISSN 0150-9861
Publisher: Elsevier
DOI: 10.1016/j.neurad.2021.09.001

Reliability of velocity pulsatility in small vessels on 3Tesla MRI in the basal ganglia: a test–retest study

Author(s): Rick J. van Tuijl, Stanley D. T. Pham, Ynte M. Ruigrok, Geert Jan Biessels, Birgitta K. Velthuis, Jaco J. M. Zwanenburg
Published in: Magnetic Resonance Materials in Physics, Biology and Medicine, Issue 36, 2023, Page(s) 15-23, ISSN 1352-8661
Publisher: Springer
DOI: 10.1007/s10334-022-01042-2

Risk Factors of Aneurysmal Subarachnoid Hemorrhage Including Analysis by Sex

Author(s): Mariam Ali, Maaike J.A. van Eldik, Stijn Rietkerken, Jan W. Schoones, Nyika D. Kruyt, Gabriel J.E. Rinkel, Marieke J.H. Wermer, Sanne Peters, Ynte M. Ruigrok
Published in: Neurology, Issue 104, 2025, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000213511

Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors

Author(s): Mark K. Bakker, Rick A. A. van der Spek, Wouter van Rheenen, Sandrine Morel, Romain Bourcier, Isabel C. Hostettler, Varinder S. Alg, Kristel R. van Eijk, Masaru Koido, Masato Akiyama, Chikashi Terao, Koichi Matsuda, Robin G. Walters, Kuang Lin, Liming Li, Iona Y. Millwood, Zhengming Chen, Guy A. Rouleau, Sirui Zhou, Kristiina Rannikmäe, Cathie L. M. Sudlow, Henry Houlden, Leonard H. van den Berg,
Published in: Nature Genetics, Issue 52/12, 2020, Page(s) 1303-1313, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-020-00725-7

Performance of a Diagnostic Model for the Presence of Unruptured Intracranial Aneurysms in the General Population

Author(s): Vita M. Klieverik, Bob Roozenbeek, Tim Y. Cras, Meike W. Vernooij, Mirjam I. Geerlings, Daniel Bos, Ynte M. Ruigrok
Published in: Cerebrovascular Diseases, 2024, Page(s) 570-578, ISSN 1015-9770
Publisher: S. Karger AG
DOI: 10.1159/000535471

Velocity Pulsatility and Arterial Distensibility Along the Internal Carotid Artery

Author(s): Rick J. van Tuijl, Ynte M. Ruigrok, Birgitta K. Velthuis, Irene C. van der Schaaf, Gabriël J. E. Rinkel, Jaco J. M. Zwanenburg
Published in: Journal of the American Heart Association, Issue 9, 2024, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/jaha.120.016883

Additional Relevant Intracranial Findings in Persons Screened with MR for Intracranial Aneurysms

Author(s): Philippine B. van Wijngaarden, Gabriel J.E. Rinkel, Irene C. van der Schaaf, Liselore A. Mensing, Ynte M. Ruigrok, Mervyn D.I. Vergouwen
Published in: Journal of the Neurological Sciences, Issue 464, 2024, Page(s) 123160, ISSN 0022-510X
Publisher: Elsevier BV
DOI: 10.1016/j.jns.2024.123160

Number of Affected Relatives, Age, Smoking, and Hypertension Prediction Score for Intracranial Aneurysms in Persons With a Family History for Subarachnoid Hemorrhage

Author(s): Charlotte C M Zuurbier, Romain Bourcier, Pacôme Constant Dit Beaufils, Richard Redon, Hubert Desal, ICAN Investigators; Anne S E Bor, Antti E Lindgren, Gabriel J E Rinkel, Jacoba P Greving, Ynte M Ruigrok
Published in: Stroke, 2022, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.121.034612

Comparing methods of detecting and segmenting unruptured intracranial aneurysms on TOF-MRAS: The ADAM challenge

Author(s): Kimberley M. Timmins, Irene C. van der Schaaf, Edwin Bennink, Ynte M. Ruigrok, Xingle An, Michael Baumgartner, Pascal Bourdon, Riccardo De Feo, Tommaso Di Noto, Florian Dubost, Augusto Fava-Sanches, Xue Feng, Corentin Giroud, Inteneural Group, Minghui Hu, Paul F. Jaeger, Juhana Kaiponen, Michał Klimont, Yuexiang Li, Hongwei Li, Yi Lin, Timo Loehr, Jun Ma, Klaus H. Maier-Hein, Guillaume Marie, Bjo
Published in: NeuroImage, Issue 238, 2021, Page(s) 118216, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2021.118216

Anatomical differences of intracranial arteries according to sex: a systematic review and meta-analysis

Author(s): M.E.H. Ophelders, M.J.A. van Eldik, I.N. Vos, Y.S. Beentjes, B.K. Velthuis, Y.M. Ruigrok
Published in: Journal of Neuroradiology, Issue 51, 2024, Page(s) 10-15, ISSN 0150-9861
Publisher: Elsevier
DOI: 10.1016/j.neurad.2023.05.005

Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity

Author(s): Mark K. Bakker, Jos P. Kanning, Gad Abraham, Amy E. Martinsen, Bendik S. Winsvold, John-Anker Zwart, Romain Bourcier, Tomonobu Sawada, Masaru Koido, Yoichiro Kamatani, Sandrine Morel, Philippe Amouyel, Stéphanie Debette, Philippe Bijlenga, Takiy Berrandou, Santhi K. Ganesh, Nabila Bouatia-Naji, Gregory Jones, Matthew Bown, HUNT All-In Stroke, CADISP group, International Consortium for Blood Press
Published in: Stroke, 2023, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.122.040715

Genome-wide association meta-analysis of spontaneous coronary artery dissection identifies risk variants and genes related to artery integrity and tissue-mediated coagulation

Author(s): David Adlam, Takiy-Eddine Berrandou, Adrien Georges, Christopher P. Nelson, Eleni Giannoulatou, Joséphine Henry, Lijiang Ma, Montgomery Blencowe, Tamiel N. Turley, Min-Lee Yang, Sandesh Chopade, Chris Finan, Peter S. Braund, Ines Sadeg-Sayoud, Siiri E. Iismaa, Matthew L. Kosel, Xiang Zhou, Stephen E. Hamby, Jenny Cheng, Lu Liu, Ingrid Tarr, David W. M. Muller, Valentina d’Escamard, Annette King
Published in: Nature Genetics, Issue 55, 2023, Page(s) 964-972, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-023-01410-1

Risk Prediction of New Intracranial Aneurysms at Follow-Up Screening in People With a Positive Family History

Author(s): Charlotte C M Zuurbier, Romain Bourcier, Pacôme Constant Dit Beaufils, Richard Redon, Hubert Desal; ICAN Investigators; Anne S E Bor, Gabriel J E Rinkel, Jacoba P Greving, Ynte M Ruigrok
Published in: Stroke, 2023, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.122.041393

Analysis of aneurysmal subarachnoid hemorrhage as a multistep process

Author(s): Ynte M. Ruigrok, Gabriel J. E. Rinkel, Han‐Sol Chang, Katharina A. M. Hackenberg, Nima Etminan, Jan H. Veldink
Published in: European Journal of Neurology, Issue 31, 2024, ISSN 1351-5101
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/ene.16118

Screening for intracranial aneurysms in persons ⩾35 years with hypertension and atherosclerotic disease who smoke(d)

Author(s): Liselore A Mensing, Rick J van Tuijl, Gerard A de Kort, Irene C van der Schaaf, Frank L Visseren, Gabriel JE Rinkel, Birgitta K Velthuis, Ynte M Ruigrok, M.J. Cramer, M.G. van der Meer, H.M. Nathoe, M. Teraa, G.J. de Borst, M. van Smeden, M.L. Bots, M.H. Emmelot-Vonk, P.A. de Jong, A.T. Lely, N.P. van der Kaaij, L.J. Kappelle, Y.M. Ruigrok, M.C. Verhaar, J.A.N. Dorresteijn, F.L.J. Visseren (chair)
Published in: European Stroke Journal, Issue 8, 2025, Page(s) 1071-1078, ISSN 2396-9873
Publisher: Sage publishing
DOI: 10.1177/23969873231193296

Sex differences in risk factor relationships with subarachnoid haemorrhage and intracranial aneurysms: a Mendelian randomisation study

Author(s): L Tschiderer, M K Bakker, D Gill, S Burgess, P Willeit, Y M Ruigrok, S A E Peters
Published in: European Journal of Preventive Cardiology, Issue 31, 2024, ISSN 2047-4873
Publisher: SAGE Publications Ltd
DOI: 10.1093/eurjpc/zwae175.095

Stroke genetics informs drug discovery and risk prediction across ancestries

Author(s): Aniket Mishra, Rainer Malik, Tsuyoshi Hachiya, Tuuli Jürgenson, Shinichi Namba, Daniel C. Posner, Frederick K. Kamanu, Masaru Koido, Quentin Le Grand, Mingyang Shi, Yunye He, Marios K. Georgakis, Ilana Caro, Kristi Krebs, Yi-Ching Liaw, Felix C. Vaura, Kuang Lin, Bendik Slagsvold Winsvold, Vinodh Srinivasasainagendra, Livia Parodi, Hee-Joon Bae, Ganesh Chauhan, Michael R. Chong, Liisa Tomppo, Ruf
Published in: Nature, Issue 611, 2022, Page(s) 115-123, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-05165-3

Reliability and Agreement of 2D and 3D Measurements on MRAs for Growth Assessment of Unruptured Intracranial Aneurysms

Author(s): K.M. Timmins, H.J. Kuijf, M.D.I. Vergouwen, M.J. Otten, Y.M. Ruigrok, B.K. Velthuis, I.C. van der Schaaf
Published in: American Journal of Neuroradiology, Issue 42, 2021, Page(s) 1598-1603, ISSN 0195-6108
Publisher: American Society of Neuoradiology
DOI: 10.3174/ajnr.a7186

Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies

Author(s): Matthew Traylor, Elodie Persyn, Liisa Tomppo, Sofia Klasson, Vida Abedi, Mark K Bakker, Nuria Torres, Linxin Li, Steven Bell, Loes Rutten-Jacobs, Daniel J Tozer, Christoph J Griessenauer, Yanfei Zhang, Annie Pedersen, Pankaj Sharma, Jordi Jimenez-Conde, Tatjana Rundek, Raji P Grewal, Arne Lindgren, James F Meschia, Veikko Salomaa, Aki Havulinna, Christina Kourkoulis, Katherine Crawford, Sandro Mar
Published in: The Lancet Neurology, Issue 20, 2022, Page(s) 351-361, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(21)00031-4

Intracranial Aneurysm Classifier Using Phenotypic Factors : An International Pooled Analysis

Author(s): Morel, Sandrine; Hostettler, Isabel C.; Spinner, Georg R.; Bourcier, Romain; Pera, Joanna; Meling, Torstein; Alg, Varinder; Houlden, Henry; Bakker, Mark; van’t Hof, Femke; Rinkel, Gabriel; Foroud, Tatiana; Lai, Dongbing; Moomaw, Charles; Worrall, Bradford; Caroff, Jildaz; Constant-dits-Beaufils, Pacôme; Karakachoff, Matilde; Rimbert, Antoine; Rouchaud, Aymeric; Gaal-Paavola, Emilia; Kaukovalta,
Published in: J Pers Med, Issue 3, 2022, ISSN 2075-4426
Publisher: Basel: MDPI AG
DOI: 10.3390/jpm12091410

Genetic investigation of fibromuscular dysplasia identifies risk loci and shared genetics with common cardiovascular diseases

Author(s): Adrien Georges, Min-Lee Yang, Takiy-Eddine Berrandou, Mark K. Bakker, Ozan Dikilitas, Soto Romuald Kiando, Lijiang Ma, Benjamin A. Satterfield, Sebanti Sengupta, Mengyao Yu, Jean-François Deleuze, Delia Dupré, Kristina L. Hunker, Sergiy Kyryachenko, Lu Liu, Ines Sayoud-Sadeg, Laurence Amar, Chad M. Brummett, Dawn M. Coleman, Valentina d’Escamard, Peter de Leeuw, Natalia Fendrikova-Mahlay, Dani
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-26174-2

Deep-learning-based extraction of circle of Willis topology with anatomical priors

Author(s): Dieuwertje Alblas, Iris N. Vos, Micha M. Lipplaa, Christoph Brune, Irene C. van der Schaaf, Mireille R. E. Velthuis, Birgitta K. Velthuis, Hugo J. Kuijf, Ynte M. Ruigrok, Jelmer M. Wolterink
Published in: Scientific Reports, Issue 14, 2024, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-024-80574-0

Haemorrhagic stroke and brain vascular malformations in women: risk factors and clinical features

Author(s): Mariam Ali, Ellis S van Etten, Saloua Akoudad, Joanna D Schaafsma, Marieke C Visser, Mahsoem Ali, Charlotte Cordonnier, Else Charlotte Sandset, Catharina J M Klijn, Ynte M Ruigrok, Marieke J H Wermer
Published in: The Lancet Neurology, Issue 23, 2024, Page(s) 625-635, ISSN 1474-4422
Publisher: The Lancet Publishing Group
DOI: 10.1016/s1474-4422(24)00122-4

Modifiable Risk Factors for Intracranial Aneurysm and Aneurysmal Subarachnoid Hemorrhage: A Mendelian Randomization Study

Author(s): Ville Karhunen, Mark K. Bakker, Ynte M. Ruigrok, Dipender Gill and Susanna C. Larsson
Published in: Journal of American Heart Association, 2021, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/jaha.121.022277

Anti-Epileptic Drug Target Perturbation and Intracranial Aneurysm Risk: Mendelian Randomization and Colocalization Study

Author(s): Mark K. Bakker, Tijmen van Straten, Michael Chong, Guillaume Paré, Dipender Gill, Ynte M. Ruigrok
Published in: Stroke, Issue 54, 2024, Page(s) 208-216, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.122.040598

Cardiovascular Risk Prediction in Men and Women Aged Under 50 Years Using Routine Care Data

Author(s): Hendrikus J. A. van Os, Jos P. Kanning, Tobias N. Bonten, Margot M. Rakers, Hein Putter, Mattijs E. Numans, Ynte M. Ruigrok, Rolf H. H. Groenwold and Marieke J. H. Wermer
Published in: JAHA, 2023, ISSN 2047-9980
Publisher: Wiley-Blackwell
DOI: 10.1161/jaha.122.027011

Aneurysm Prevalence and Quality of Life During Screening in Relatives of Patients With Unruptured Intracranial Aneurysms

Author(s): Liselore A. Mensing, Rick J. van Tuijl, Jacoba P. Greving, Birgitta K. Velthuis, Irene C. van der Schaaf, Marieke J.H. Wermer, Dagmar Verbaan, W. Peter Vandertop, Nicolaas P.A. Zuithoff, Gabriël J.E. Rinkel, Ynte M. Ruigrok
Published in: Neurology, Issue 101, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000207475

A Genome-Wide Association Study of Outcome After Aneurysmal Subarachnoid Haemorrhage: Discovery Analysis

Author(s): Ben Gaastra; Sheila Alexander; Mark K. Bakker; Hemant Bhagat; Philippe Bijlenga; Spiros L. Blackburn; Malie K. Collins; Sylvain Doré; Christoph J. Griessenauer; Philipp Hendrix; Eun Pyo Hong; Isabel C. Hostettler; Henry Houlden; Koji IIhara; Jin Pyeong Jeon; Bong Jun Kim; Jiang Li; Sandrine Morel; Paul Nyquist; Dianxu Ren; Ynte M. Ruigrok; David Werring; Will Tapper; Ian Galea; Diederik Bulters
Published in: Transl Stroke Res, Issue 1, 2022, ISSN 1868-4483
Publisher: Springer Pub. Co.,
DOI: 10.1007/s12975-022-01095-4

Genome-Wide Association Study of Clinical Outcome After Aneurysmal Subarachnoid Haemorrhage: Protocol

Author(s): Ben Gaastra; Sheila Alexander; Mark K. Bakker; Hemant Bhagat; Philippe Bijlenga; Spiros Blackburn; Malie K. Collins; Sylvain Doré; Christoph Griessenauer; Philipp Hendrix; Eun Pyo Hong; Isabel C. Hostettler; Henry Houlden; Koji IIhara; Jin Pyeong Jeon; Bong Jun Kim; Munish Kumar; Sandrine Morel; Paul Nyquist; Dianxu Ren; Ynte M. Ruigrok; David Werring; Ian Galea; Diederik Bulters; Will Tapper
Published in: Transl Stroke Res, Issue 18684483, 2022, ISSN 1868-4483
Publisher: Springer Pub. Co.,
DOI: 10.1007/s12975-021-00978-2

Developing Clinical Prediction Models Using Primary Care Electronic Health Record Data: The Impact of Data Preparation Choices on Model Performance

Author(s): Hendrikus J. A. van Os, Jos P. Kanning, Marieke J. H. Wermer, Niels H. Chavannes, Mattijs E. Numans, Ynte M. Ruigrok, Erik W. van Zwet, Hein Putter, Ewout W. Steyerberg and Rolf H. H. Groenwold
Published in: Front. Epidemiol, 2022, ISSN 2674-1199
Publisher: Frontiers Media SA
DOI: 10.3389/fepid.2022.871630

Genetics of Intracranial Aneurysms

Author(s): Mark K. Bakker, Ynte M. Ruigrok
Published in: Stroke, Issue 52, 2024, Page(s) 3004-3012, ISSN 0039-2499
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1161/strokeaha.120.032621

Development of a questionnaire to identify persons with a family history of aneurysmal subarachnoid hemorrhage

Author(s): Charlotte CM Zuurbier; Jacoba P Greving; Gabriel JE Rinkel; Ynte M Ruigrok
Published in: Int J Stroke, Issue 3, 2022, ISSN 2158-2440
Publisher: SAGE Publications Inc.
DOI: 10.1177/17474930211069004

Prediction of aneurysmal subarachnoid hemorrhage in comparison with other stroke types using routine care data

Author(s): Jos P. Kanning, Hendrikus J. A. van Os, Margot Rakers, Marieke J. H. Wermer, Mirjam I. Geerlings, Ynte M. Ruigrok
Published in: PLOS ONE, Issue 19, 2024, Page(s) e0303868, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0303868

Development and external validation of the SMA<sup>2</sup>SH<sup>2</sup>ERS risk prediction model for aneurysmal subarachnoid haemorrhage in the general population: a population-based prospective cohort study

Author(s): Vita M. Klieverik, Jos P. Kanning, Ina L. Rissanen, Kristiina Rannikmae, Amy E. Martinsen, Bendik S. Winsvold, Mirjam I. Geerlings, Ynte M. Ruigrok
Published in: BMJ Open, Issue 15, 2025, Page(s) e091756, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2024-091756

Preventive screening for intracranial aneurysms

Author(s): Gabriel JE Rinkel, Ynte M Ruigrok
Published in: International Journal of Stroke, 2021, Page(s) 174749302110245, ISSN 1747-4930
Publisher: Blackwell
DOI: 10.1177/17474930211024584

Intra-Aneurysmal High-Resolution 4D MR Flow Imaging for Hemodynamic Imaging Markers in Intracranial Aneurysm Instability

Author(s): R.J. van Tuijl, C.S. den Hertog, K.M. Timmins, B.K. Velthuis, P. van Ooij, J.J.M. Zwanenburg, Y.M. Ruigrok, I.C. van der Schaaf
Published in: American Journal of Neuroradiology, Issue 45, 2025, Page(s) 1678-1684, ISSN 0195-6108
Publisher: American Society of Neuoradiology
DOI: 10.3174/ajnr.a8380

Prescribed Drug Use and Aneurysmal Subarachnoid Hemorrhage Incidence

Author(s): Jos P. Kanning, Shahab Abtahi, Christian Schnier, Olaf H. Klungel, Mirjam I. Geerlings, Ynte M. Ruigrok
Published in: Neurology, Issue 102, 2024, ISSN 0028-3878
Publisher: Lippincott Williams & Wilkins Ltd.
DOI: 10.1212/wnl.0000000000209479

Serial Quality of Life Assessment around Screening for Familial Intracranial Aneurysms: A Prospective Cohort Study

Author(s): Liselore A. Mensing, Keneshka Atash, Gabriel J.E. Rinkel, Ynte M. Ruigrok
Published in: Cerebrovascular Diseases, Issue 53, 2024, Page(s) 428-436, ISSN 1015-9770
Publisher: S. Karger AG
DOI: 10.1159/000534373

Sex-specific anatomical variation of circle of Willis arteries

Author(s): Phebe J. Groenheide, Iris N. Vos, Robin Bülow, Irene C. van der Schaaf, Birgitta K. Velthuis, Ynte M. Ruigrok
Published in: NeuroImage, Issue 307, 2025, Page(s) 121035, ISSN 1053-8119
Publisher: Academic Press
DOI: 10.1016/j.neuroimage.2025.121035

Sex-specific association between anatomical variants of the circle of Willis and intracranial aneurysms in individuals with a familial predisposition

Author(s): Marloes H.A. Nanninga, Denise A.M. van Strien, Birgitta K. Velthuis, Mireille R.E. Velthuis, Iris N. Vos, Phebe J. Groenheide, Ynte M. Ruigrok, Irene C. van der Schaaf
Published in: American Journal of Neuroradiology, 2025, Page(s) ajnr.A8690, ISSN 0195-6108
Publisher: American Society of Neuoradiology
DOI: 10.3174/ajnr.a8690

Heritability of territory of ruptured and unruptured intracranial aneurysms in families

Author(s): Mayte Sánchez van Kammen, Romain Bourcier, Charles J. Moomaw, Joseph P. Broderick, Daniel Woo, Chrysanthi Papagiannaki, Olivier Levrier, Antti E. Lindgren, Timo Koivisto, Juha E. Jääskeläinen, Gabriël J. E. Rinkel, Ynte M. Ruigrok
Published in: PLOS ONE, Issue 15, 2020, Page(s) e0236714, ISSN 1932-6203
Publisher: Public Library of Science
DOI: 10.1371/journal.pone.0236714

Improving automated intracranial artery labeling using atlas-based features in graph convolutional nets

Author(s): I. N. Vos, Y. M. Ruigrok, K. M. Timmins, B. K. Velthuis, H. J. Kuijf
Published in: Proceedings Volume 12032, Medical Imaging 2022: Image Processing; 1203217 (2022), 2022
Publisher: SPIE Medical Imaging,
DOI: 10.1117/12.2611747

Automatic cerebral vessel extraction in TOF-MRA using deep learning

Author(s): V. de Vos, K. M. Timmins, I. C. van der Schaaf, Y. Ruigrok, B. K. Velthuis, H. J. Kuijf
Published in: Proceedings Volume 11596, Medical Imaging 2021: Image Processing; 115962F (2021), 2021
Publisher: SPIE Medical Imaging
DOI: 10.1117/12.2581226

Relationship between diameter asymmetry of the anterior cerebral arteries of the Circle of Willis and asymmetry in diameters and blood flow of the upstream vasculature: preliminary results

Author(s): Rick J. van Tuijl, Iris N. Vos, Ynte M. Ruigrok, Irene C. van der Schaaf, Birgitta K. Velthuis, Jaco J. M. Zwanenburg
Published in: Proceedings Volume 12036, Medical Imaging 2022: Biomedical Applications in Molecular, Structural, and Functional Imaging; 1203604 (2022), 2022
Publisher: SPIE Medical Imaging,
DOI: 10.1117/12.2611485

Assessment of manual and automated intracranial artery diameter measurements

Author(s): I. N. Vos, M. E. H. Ophelders, Y. M. Ruigrok, B. K. Velthuis M.D., H. J. Kuijf
Published in: Proceedings Volume 12035, Medical Imaging 2022: Image Perception, Observer Performance, and Technology Assessment; 1203504 (2022), 2022
Publisher: SPIE Medical Imaging,
DOI: 10.1117/12.2611777

Assessment of imaging markers for intracranial aneurysms using artificial intelligence

Author(s): Iris Vos
Published in: 2025
Publisher: Utrecht University

Intracranial aneurysms: Towards better screening and prediction of rupture

Author(s): Liselore Mensing
Published in: 2023
Publisher: Utrecht University

Genetics of intracranial aneurysms and amyotrophic lateral sclerosis

Author(s): null null, Mark Kevin Bakker
Published in: 2022
Publisher: Utrecht University Library
DOI: 10.33540/1204

Aneurysmal Subarachnoid Haemorrhage: Insights through Data-Driven Population Studies

Author(s): Jos Kanning
Published in: 2025
Publisher: Utrecht University

Intracranial aneurysms : family history and risk of rupture

Author(s): Charlotte Zuurbier
Published in: 2021
Publisher: Utrecht University

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