Prevention of childhood Acute Lymphoblastic Leukemia immunology links oncology

Project Information

PreventALL

Grant agreement ID: 852222

DOI 10.3030/852222

EC signature date 20 February 2020

Start date 1 July 2020

End date 30 June 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 498 925,00

EU contribution € 1 498 925,00

Coordinated by

KLINIKUM RECHTS DER ISAR DER TECHNISCHEN UNIVERSITAT MUNCHEN
Germany

Publications

Peer reviewed articles (8)

Regional BCG vaccination policy in former East- and West Germany may impact on both severity of SARS-CoV-2 and incidence of childhood leukemia

Author(s): Julia Hauer; Ute Fischer; Franziska Auer; Arndt Borkhardt
Published in: Leukemia, Issue 34, 2020, Page(s) 2217–2219, ISSN 0887-6924
Publisher: Nature Publishing Group
DOI: 10.1038/s41375-020-0871-4

Germline POT1 Deregulation Can Predispose to Myeloid Malignancies in Childhood

Author(s): Pia Michler; Anne Schedel; Martha Witschas; Ulrike Anne Friedrich; Rabea Wagener; Juha Mehtonen; Triantafyllia Brozou; Maria Menzel; Carolin Walter; Dalileh Nabi; Glen Pearce; Miriam Erlacher; Gudrun Göhring; Martin Dugas; Merja Heinäniemi; Arndt Borkhardt; Friedrich Stölzel; Julia Hauer; Franziska Auer
Published in: International Journal of Molecular Sciences, Issue Volume 22, Issue 21, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390//ijms222111572

Multicomponent Synthesis, Binding Mode, and Structure−ActivityRelationship of Selective Histone Deacetylase 6 (HDAC6) Inhibitorswith Bifurcated Capping Groups

Author(s): Nina Reßing, Melf Sönnichsen, Jeremy D. Osko, Andrea Schöler, Julian Schliehe-Diecks, Alexander Skerhut, Arndt Borkhardt, Julia Hauer, Matthias U. Kassack, David. W. Christianson, Sanil Bhatia and Finn K. Hansen
Published in: Journal of Medicanial Chemistry, Issue 63 (18), 2020, Page(s) 10339-10351, ISSN 0022-2623
Publisher: American Chemical Society
DOI: 10.1021/acs.jmedchem.9b01888

Toward prevention of childhood ALL by early-life immune training

Author(s): Julia Hauer; Ute Fischer; Arndt Borkhardt
Published in: blood, Issue Volume 138, Issue 16, 2021, Page(s) 1412-1428, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2020009895

Recurrent Germline Variant in RAD21 Predisposes Children to Lymphoblastic Leukemia or Lymphoma

Author(s): Anne Schedel, Ulrike Anne Friedrich, Mina N F Morcos, Rabea Wagener, Juha Mehtonen, Titus Watrin, Claudia Saitta, Triantafyllia Brozou, Pia Michler, Carolin Walter, Asta Försti, Arka Baksi, Maria Menzel, Peter Horak, Nagarajan Paramasivam, Grazia Fazio, Robert J Autry, Stefan Fröhling, Meinolf Suttorp, Christoph Gertzen, Holger Gohlke, Sanil Bhatia, Karin Wadt, Kjeld Schmiegelow, Martin Dugas, D
Published in: International Journal of Molecular Sciences, Issue 23(9), 2022, Page(s) 5174, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23095174

Cytokine Hyperresponsiveness in Children With ETV6::RUNX1-positive Acute Lymphoblastic Leukemia After Challenge With Common Pathogens

Author(s): Nadine Rüchel, Marina Oldenburg, Stefan Janssen, Aleksandra A Pandyra, Wei Liu, Eleni Vasileiou, Daniel Hein, Vera Helena Jepsen, Ute Fischer, Daniel Picard, Gesine Kögler, Julia Hauer, Franziska Auer, Angelina Beer, Ortwin Adams, Colin MacKenzie, Martin Jaeger, Mihai G Netea, Arndt Borkhardt, Katharina L Gössling
Published in: Hemasphere, Issue 7(2), 2023, Page(s) e835, ISSN 2572-9241
Publisher: Wolters Kluwer Health, Inc.
DOI: 10.1097/hs9.0000000000000835

An intact gut microbiome protects genetically predisposed mice against leukemia

Author(s): Carolina Vicente-Dueñas, Stefan Janssen, Marina Oldenburg, Franziska Auer, Inés González-Herrero, Ana Casado-García, Marta Isidro-Hernández, Javier Raboso-Gallego, Philipp Westhoff, Aleksandra A. Pandyra, Daniel Hein, Katharina L. Gössling, Diego Alonso-López, Javier De Las Rivas, Sanil Bhatia, Francisco Javier García-Criado, María Begoña García-Cenador, Andreas P. M. Weber, Karl Köhre
Published in: Blood, Issue Volume 136, Issue 18, 2021, Page(s) 2003-2017, ISSN 0006-4971
Publisher: American Society of Hematology
DOI: 10.1182/blood.2019004381

Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization

Author(s): Sanil Bhatia, Lukas Spanier, David Bickel, Niklas Dienstbier, Vitalij Woloschin, Melina Vogt, Henrik Pols, Beate Lungerich, Jens Reiners, Narges Aghaallaei, Daniela Diedrich, Benedikt Frieg, Julian Schliehe-Diecks, Bertan Bopp, Franziska Lang, Mohanraj Gopalswamy, Jennifer Loschwitz, Baubak Bajohgli, Julia Skokowa, Arndt Borkhardt, Julia Hauer, Finn K Hansen, Sander H J Smits, Joachim Jose, Holger
Published in: ACS Central Science, Issue 8 (5), 2022, Page(s) 636−655, ISSN 2374-7943
Publisher: ACS Publications
DOI: 10.1021/acscentsci.2c00013