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Algorithms and multiplex assays for integrated serological surveillance of malaria and neglected tropical diseases

Project description

Novel integrated serological surveillance of malaria and neglected tropical diseases

Malaria and neglected tropical diseases (NTDs) like lymphatic filariasis, onchocerciasis, trachoma and schistosomiasis affect 2 billion people yearly. Successfully targeting these diseases calls for integrated surveillance strategies. Malaria surveillance is routinely implemented through cross-sectional surveys; this provides as an opportunity to introduce serological testing by measuring antibodies to multiple pathogens in blood samples collected for malaria surveillance. The goal of the EU-funded MultiSeroSurv project is to characterise the sero-epidemiology of malaria and NTDs in longitudinal cohort studies in Ethiopia, Cambodia, Papua New Guinea and Senegal, measuring antibodies to 34 antigens from 12 pathogens in the single blood samples. The collected data will provide validation for the use of serology in detecting infections and determining how concurrent and past exposures to multiple parasites can be estimated through multiplex data analysis from cross-sectional surveys.

Field of science

  • /medical and health sciences/health sciences/infectious disease/malaria
  • /medical and health sciences/health sciences/tropical medicine

Call for proposal

ERC-2019-STG
See other projects for this call

Funding Scheme

ERC-STG - Starting Grant

Host institution

INSTITUT PASTEUR
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
France
Activity type
Research Organisations
EU contribution
€ 1 174 500

Beneficiaries (2)

INSTITUT PASTEUR
France
EU contribution
€ 1 174 500
Address
Rue Du Docteur Roux 25-28
75724 Paris Cedex 15
Activity type
Research Organisations
INSTITUT PASTEUR DE DAKAR
Senegal
EU contribution
€ 325 500
Address
Avenue Pasteur 36
DAKAR Dakar
Activity type
Research Organisations