Understanding how mitochondria compete with Toxoplasma for nutrients to defend the host cell

Project Information

MITOvTOXO

Grant agreement ID: 852457

DOI

10.3030/852457

Project closed

EC signature date 13 December 2019

Start date 1 June 2020

End date 31 May 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN EV
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Mitochondria shed their outer membrane in response to infection-induced stress

Author(s): Xianhe Li, Julian Straub, T nia Catarina Medeiros, Chahat Mehra, Fabian den Brave, Esra Peker, Ilian Atanassov, Katharina Stillger, Jonas Benjamin Michaelis, Emma Burbridge, Colin Adrain, Christian Münch, Jan Riemer, Thomas Becker, Lena F. Pernas
Published in: Science, 2022, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.abi4343

Cellular metabolism in the defense against microbes

Author(s): Lena Pernas
Published in: Journal of Cell Science, 2021, ISSN 0021-9533
Publisher: The Company of Biologists Ltd.
DOI: 10.1242/jcs.252023

Mitochondria protect against an intracellular pathogen by restricting access to folate

Author(s): Tânia Catarina Medeiros, Jana Ovciarikova, Xianhe Li, Patrick Krueger, Tim Bartsch, Silvia Reato, John C. Crow, Michelle Tellez Sutterlin, Bruna Martins Garcia, Irina Rais, Kira Allmeroth, Matías D. Hartman, Martin S. Denzel, Martin Purrio, Andrea Mesaros, Kit-Yi Leung, Nicholas D. E. Greene, Lilach Sheiner, Patrick Giavalisco, Lena Pernas
Published in: Science, Issue 389, 2025, ISSN 0036-8075
Publisher: American Association for the Advancement of Science
DOI: 10.1126/science.adr6326

Glutamine sensing licenses cholesterol synthesis

Author(s): Bruna Martins Garcia, Philipp Melchinger, Tania Medeiros, Sebastian Hendrix, Kavan Prabhu, Mauro Corrado, Jenina Kingma, Andrej Gorbatenko, Soni Deshwal, Matteo Veronese, Luca Scorrano, Erika Pearce, Patrick Giavalisco, Noam Zelcer, Lena Pernas
Published in: The EMBO Journal, Issue 43, 2024, Page(s) 5837-5856, ISSN 1460-2075
Publisher: The EMBO Journal
DOI: 10.1038/s44318-024-00269-0

Contact and competition between mitochondria and microbes

Author(s): Tânia C Medeiros 1, Chahat Mehra 1, Lena Pernas 2
Published in: Current Opinion in MIcrobiology, 2021, ISSN 1369-5274
Publisher: Elsevier BV
DOI: 10.1016/j.mib.2021.07.014