Overcoming the Barriers of Brain Cancer Treatment: Targeted and Fully NIR Absorbing Photodynamic Therapy Agents with Extremely Low Molecular Weights and Controlled Lipophilicity

Project Information

INFRADYNAMICS

Grant agreement ID: 852614

DOI

10.3030/852614

Project closed

EC signature date 18 October 2019

Start date 1 November 2019

End date 31 October 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 500 000,00

EU contribution

€ 1 500 000,00

Coordinated by

MIDDLE EAST TECHNICAL UNIVERSITY
Türkiye

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Xanthene dyes for cancer imaging and treatment: A material odyssey

Author(s): Osman Karaman, Gizem Atakan Alkan, Caglayan Kizilenis, Cevahir Ceren Akgul, Gorkem Gunbas
Published in: Coordination Chemistry Reviews, Issue 475, 2025, Page(s) 214841, ISSN 0010-8545
Publisher: Elsevier BV
DOI: 10.1016/j.ccr.2022.214841

Resorufin Enters the Photodynamic Therapy Arena: A Monoamine Oxidase Activatable Agent for Selective Cytotoxicity

Author(s): Toghrul Almammadov, Gizem Atakan, Ozen Leylek, Gulnihal Ozcan, Gorkem Gunbas, Safacan Kolemen
Published in: ACS Medicinal Chemistry Letters, Issue 11/12, 2020, Page(s) 2491-2496, ISSN 1948-5875
Publisher: American Chemical Society
DOI: 10.1021/acsmedchemlett.0c00484

Drastic Impact of Donor Substituents on Xanthenes in the PDT of Glioblastoma

Author(s): O. Karaman, E. Yesilcimen, M. Forough, Z. Elmazoglu, G. Gunbas
Published in: JACS Au, 2025, ISSN 2691-3704
Publisher: American Chemical Society (ACS)
DOI: 10.1021/jacsau.5c00738

Balanced Intersystem Crossing in Iodinated Silicon-Fluoresceins Allows New Class of Red Shifted Theranostic Agents

Author(s): Sultan Cetin, Zubeyir Elmazoglu, Osman Karaman, Hande Gunduz, Gorkem Gunbas, Safacan Kolemen
Published in: ACS Medicinal Chemistry Letters, Issue 12/5, 2021, Page(s) 752-757, ISSN 1948-5875
Publisher: American Chemical Society
DOI: 10.1021/acsmedchemlett.1c00018

Locked and Loaded: β-Galactosidase Activated Photodynamic Therapy Agent Enables Selective Imaging and Targeted Treatment of Glioblastoma Multiforme Cancer Cells

Author(s): Toghrul Almammadov, Zubeyir Elmazoglu, Gizem Atakan, Dilay Kepil, Guzide Aykent, Safacan Kolemen, Gorkem Gunbas
Published in: ACS Applied Bio Materials, Issue 5, 2023, Page(s) 4284-4293, ISSN 2576-6422
Publisher: American Chemical Society (ACS)
DOI: 10.1021/acsabm.2c00484

Intellectual Property Rights

Other (1)

NEAR-INFRARED (NIR) ABSORBING PHOTOSENSITIZERS

Application/Publication number: WO /2020/005172
Date: 2018-06-25
Applicant(s): MIDDLE EAST TECHNICAL UNIVERSITY