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Promyelocytic leukemia protein (PML) outside the tumor: a new player in the control of inflammation

Publications

Some Insights into the Regulation of Cardiac Physiology and Pathology by the Hippo Pathway

Author(s): Daniela Ramaccini; Gaia Pedriali; Mariasole Perrone; Esmaa Bouhamida; Lorenzo Modesti; Mariusz R. Wieckowski; Carlotta Giorgi; Paolo Pinton; Giampaolo Morciano
Published in: Crossref, Issue 2, 2022, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines10030726

Mitochondrial Ca 2+ Signaling in Health, Disease and Therapy

Author(s): orenzo Modesti , Alberto Danese , Veronica Angela Maria Vitto , Daniela Ramaccini , Gianluca Aguiari, Roberta Gafà , Giovanni Lanza , Carlotta Giorgi , Paolo Pinton
Published in: Cells, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10061317

TFG binds LC3C to regulate ULK1 localization and autophagosome formation

Author(s): Marianna Carinci , Beatrice Testa, Matteo Bordi , Giacomo Milletti , Massimo Bonora , Laura Antonucci , Caterina Ferraina, Marta Carro, Mukesh Kumar , Donatella Ceglie , Franziska Eck, Roberta Nardacci , Francois le Guerroué , Stefania Petrini , Maria E Soriano , Ignazio Caruana , Valentina Doria , Maria Manifava , Camille Peron , Matteo Lambrughi , Valeria Tiranti , Christian Behrends , Elena Pa
Published in: The EMBO journal., 2021, ISSN 1460-2075
Publisher: Published for the European Molecular Biology Organization by IRL Press, [c1982-
DOI: 10.15252/embj.2019103563

Cell death as a result of calcium signaling modulation: A cancer-centric prospective.

Author(s): Alberto Danese; Sara Leo; Alessandro Rimessi; Mariusz R. Wieckowski; Francesco Fiorica; Carlotta Giorgi; Paolo Pinton
Published in: Biochimica et biophysica acta. Molecular cell research, Issue 5, 2021, ISSN 1879-2596
Publisher: Elsevier
DOI: 10.1016/j.bbamcr.2021.119061

Mitochondrial Ca2+ Signaling in Health, Disease and Therapy.

Author(s): Lorenzo Modesti; Alberto Danese; Veronica Angela Maria Vitto; Daniela Ramaccini; Gianluca Aguiari; Roberta Gafà; Giovanni Lanza; Carlotta Giorgi; Paolo Pinton
Published in: Cells, Vol 10, Iss 1317, p 1317 (2021), Issue 1, 2021, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells10061317

Different Roles of Mitochondria in Cell Death and Inflammation: Focusing on Mitochondrial Quality Control in Ischemic Stroke and Reperfusion

Author(s): Marianna Carinci, Bianca Vezzani, Simone Patergnani, Peter Ludewig, Katrin Lessmann, Tim Magnus, Ilaria Casetta, Maura Pugliatti, Paolo Pinton, Carlotta Giorgi
Published in: Biomedicines, Issue 9/2, 2021, Page(s) 169, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9020169

Antipsychotic drugs counteract autophagy and mitophagy in multiple sclerosis

Author(s): Simone Patergnani 1, Massimo Bonora 1, Selene Ingusci 2, Maurizio Previati 3, Saverio Marchi 4, Silvia Zucchini 2, Mariasole Perrone 1, Mariusz R Wieckowski 5, Massimiliano Castellazzi 6 7, Maura Pugliatti 6 7, Carlotta Giorgi 8, Michele Simonato 9 10, Paolo Pinton 8 7
Published in: Proceedings of the National Academy of Sciences of the United States of America, 2021, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2020078118

An Updated Understanding of the Role of YAP in Driving Oncogenic Responses.

Author(s): Giampaolo Morciano; Bianca Vezzani; Sonia Missiroli; Caterina Boncompagni; Paolo Pinton; Carlotta Giorgi
Published in: Cancers, Issue 5, 2021, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13123100

Ca2+ Fluxes and Cancer.

Author(s): Saverio Marchi; Carlotta Giorgi; Lorenzo Galluzzi; Paolo Pinton
Published in: Molecular cell., Issue 3, 2020, ISSN 1097-4164
Publisher: Cell Press
DOI: 10.1016/j.molcel.2020.04.017

The Dichotomous Role of Inflammation in the CNS: A Mitochondrial Point of View

Author(s): Bianca Vezzani, Marianna Carinci, Simone Patergnani, Matteo P. Pasquin, Annunziata Guarino, Nimra Aziz, Paolo Pinton, Michele Simonato, Carlotta Giorgi
Published in: Biomolecules, Issue 10/10, 2020, Page(s) 1437, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom10101437

Relevance of Autophagy and Mitophagy Dynamics and Markers in Neurodegenerative Diseases.

Author(s): Carlotta Giorgi; Esmaa Bouhamida; Alberto Danese; Maurizio Previati; Paolo Pinton; Simone Patergnani
Published in: Biomedicines, Issue 5, 2021, ISSN 2227-9059
Publisher: MDPI AG
DOI: 10.3390/biomedicines9020149

From Bed to Bench and Back: TNF-α, IL-23/IL-17A, and JAK-Dependent Inflammation in the Pathogenesis of Psoriatic Synovitis

Author(s): Ettore Silvagni , Sonia Missiroli, Mariasole Perrone , Simone Patergnani , Caterina Boncompagni, Alessandra Bortoluzzi , Marcello Govoni , Carlotta Giorgi , Stefano Alivernini , Paolo Pinton , Carlo Alberto Scirè
Published in: Frontiers in pharmacology, 2021, ISSN 1663-9812
Publisher: Frontiers Media S.A.
DOI: 10.3389/fphar.2021.672515

Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy

Author(s): Jiaming Xue, Simone Patergnani, Carlotta Giorgi, Joelle Suarez, Keisuke Goto, Angela Bononi , Mika Tanji, Flavia Novelli , Sandra Pastorino , Ronghui Xu , Natascia Caroccia , A Umran Dogan, Harvey I Pass, Mauro Tognon, Paolo Pinton, Giovanni Gaudino, Tak W Mak, Michele Carbone, Haining Yang
Published in: Proceedings of the National Academy of Sciences of the United States of America, 2020, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2007622117

Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase

Author(s): Anna Fantinati; Giampaolo Morciano; Giulia Turrin; Gaia Pedriali; Salvatore Pacifico; Delia Preti; Valentina Albanese; Davide Illuminati; Virginia Cristofori; Carlotta Giorgi; Elena Tremoli; Paolo Pinton; Claudio Trapella
Published in: Crossref, Issue 1, 2022, ISSN 1464-3405
Publisher: Pergamon Press
DOI: 10.1016/j.bmcl.2022.128822

BAP1 forms a trimer with HMGB1 and HDAC1 that modulates gene × environment interaction with asbestos

Author(s): Flavia Novelli, Angela Bononi , Qian Wang , Fang Bai , Simone Patergnani , Franz Kricek , Ellinor Haglund , Joelle S Suarez , Mika Tanji , Ronghui Xu , Yasutaka Takanishi , Michael Minaai , Sandra Pastorino , Paul Morris , Greg Sakamoto , Harvey I Pass , Haithem Barbour , Giovanni Gaudino , Carlotta Giorgi , Paolo Pinton , Jose N Onuchic , Haining Yang , Michele Carbone
Published in: Proceedings of the National Academy of Sciences of the United States of America, 2021, ISSN 1091-6490
Publisher: National Academy of Sciences
DOI: 10.1073/pnas.2111946118

Aortic Valve Stenosis and Mitochondrial Dysfunctions: Clinical and Molecular Perspectives

Author(s): Gaia Pedriali; Giampaolo Morciano; Simone Patergnani; Paolo Cimaglia; Cristina Morelli; Elisa Mikus; Roberto Ferrari; Vincenzo Gasbarro; Carlotta Giorgi; Mariusz R. Wieckowski; Paolo Pinton
Published in: International Journal of Molecular Sciences, Issue 12, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21144899

Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology.

Author(s): Massimo Bonora; Simone Patergnani; Daniela Ramaccini; Giampaolo Morciano; Gaia Pedriali; Asrat Endrias Kahsay; Esmaa Bouhamida; Carlotta Giorgi; Mariusz R. Wieckowski; Paolo Pinton
Published in: Biomolecules, Vol 10, Iss 998, p 998 (2020), Issue 12, 2020, ISSN 2218-273X
Publisher: MDPI
DOI: 10.3390/biom10070998

Understanding the Role of Autophagy in Cancer Formation and Progression Is a Real Opportunity to Treat and Cure Human Cancers

Author(s): Simone Patergnani , Sonia Missiroli , Giampaolo Morciano , Mariasole Perrone , Cristina M Mantovani , Gabriele Anania , Francesco Fiorica , Paolo Pinton , Carlotta Giorgi
Published in: Cancers, 2021, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13225622

Various Aspects of Calcium Signaling in the Regulation of Apoptosis, Autophagy, Cell Proliferation, and Cancer

Author(s): Simone Patergnani, Alberto Danese, Esmaa Bouhamida, Gianluca Aguiari, Maurizio Previati, Paolo Pinton, Carlotta Giorgi
Published in: International journal of molecular sciences, 2020, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21218323

Cancer-Related Increases and Decreases in Calcium Signaling at the Endoplasmic Reticulum-Mitochondria Interface (MAMs)

Author(s): Alberto Danese, Saverio Marchi, Veronica Angela Maria Vitto, Lorenzo Modesti, Sara Leo, Mariusz R Wieckowski, Carlotta Giorgi, Paolo Pinton
Published in: Reviews of physiology, biochemistry and pharmacology, 2020, ISSN 0303-4240
Publisher: Springer Verlag
DOI: 10.1007/112_2020_43

Methods to Monitor Mitophagy and Mitochondrial Quality: Implications in Cancer, Neurodegeneration, and Cardiovascular Diseases

Author(s): Simone Patergnani, Massimo Bonora, Esmaa Bouhamida , Alberto Danese , Saverio Marchi, Giampaolo Morciano, Maurizio Previati, Gaia Pedriali, Alessandro Rimessi, Gabriele Anania , Carlotta Giorgi, Paolo Pinton
Published in: Methods in molecular biology (Clifton, N.J.), 2021, ISSN 1940-6029
Publisher: Humana Press
DOI: 10.1007/978-1-0716-1433-4_9

Inflammatory Microenvironment in Early Non-Small Cell Lung Cancer: Exploring the Predictive Value of Radiomics

Author(s): Mariasole Perrone; Edoardo Raimondi; Matilde Costa; Gianluca Rasetto; Roberto Rizzati; Giovanni Lanza; Roberta Gafà; Giorgio Cavallesco; Nicola Tamburini; Pio Maniscalco; Maria Cristina Mantovani; Umberto Tebano; Manuela Coeli; Sonia Missiroli; Massimo Tilli; Paolo Pinton; Carlotta Giorgi; Francesco Fiorica
Published in: Cancers; Volume 14; Issue 14; Pages: 3335, Issue 1, 2022, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14143335

Synthesis and NLRP3-Inflammasome Inhibitory Activity of the Naturally Occurring Velutone F and of Its Non-Natural Regioisomeric Chalconoids

Author(s): Tiziano De Ventura; Mariasole Perrone; Sonia Missiroli; Paolo Pinton; Paolo Marchetti; Giovanni Strazzabosco; Giulia Turrin; Davide Illuminati; Virginia Cristofori; Anna Fantinati; Martina Fabbri; Carlotta Giorgi; Claudio Trapella; Vinicio Zanirato
Published in: International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 8957, Issue 1, 2022, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23168957

Epigenetic Regulation: A Link between Inflammation and Carcinogenesis

Author(s): Bianca Vezzani; Marianna Carinci; Maurizio Previati; Stefania Giacovazzi; Mario Della Sala; Roberta Gafà; Giovanni Lanza; Mariusz R. Wieckowski; Paolo Pinton; Carlotta Giorgi
Published in: Crossref, Issue 3, 2021, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers14051221

The Interplay of Hypoxia Signaling on Mitochondrial Dysfunction and Inflammation in Cardiovascular Diseases and Cancer: From Molecular Mechanisms to Therapeutic Approaches

Author(s): Esmaa Bouhamida; Giampaolo Morciano; Mariasole Perrone; Asrat E. Kahsay; Mario Della Sala; Mariusz R. Wieckowski; Francesco Fiorica; Paolo Pinton; Carlotta Giorgi; Simone Patergnani
Published in: Crossref, Issue 3, 2021, ISSN 2079-7737
Publisher: MDPI
DOI: 10.3390/biology11020300

Mitochondrial Bioenergetics and Dynamism in the Failing Heart

Author(s): Giampaolo Morciano, Veronica Angela Maria Vitto , Esmaa Bouhamida , Carlotta Giorgi, Paolo Pinton
Published in: Life (Basel), 2021, ISSN 2075-1729
Publisher: MDPI AG
DOI: 10.3390/life11050436

Similarities between fibroblasts and cardiomyocytes in the study of the permeability transition pore

Author(s): Giampaolo Morciano , Gaia Pedriali , Elisa Mikus , Paolo Cimaglia , Simone Calvi , Rita Pavasini , Alberto Albertini , Roberto Ferrari , Mariusz R Wieckowski , Carlotta Giorgi , Gianluca Campo , Paolo Pinton
Published in: Eur J Clin Invest, 2022, ISSN 1365-2362
Publisher: Springer-Verlag on behalf of the European Society for Clinical Investigation.
DOI: 10.1111/eci.13764

Defective endoplasmic reticulum-mitochondria contacts and bioenergetics in SEPN1-related myopathy

Author(s): Anne Filipe, Alexander Chernorudskiy , Sandrine Arbogast, Ersilia Varone, Rocío-Nur Villar-Quiles, Diego Pozzer, Maryline Moulin, Stefano Fumagalli, Eva Cabet, Swati Dudhal, Maria-Grazia De Simoni, Raphaël Denis , Nathalie Vadrot , Corinne Dill, Matteo Giovarelli, Luke Szweda, Clara De Palma, Paolo Pinton, Carlotta Giorgi, Carlo Viscomi, Emilio Clementi , Sonia Missiroli , Simona Boncompagni , E
Published in: Cell death and differentiation, 2020, ISSN 1476-5403
Publisher: Edward Arnold
DOI: 10.1038/s41418-020-0587-z

Different Roles of Mitochondria in Cell Death and Inflammation: Focusing on Mitochondrial Quality Control in Ischemic Stroke and Reperfusion.

Author(s): Marianna Carinci; Bianca Vezzani; Simone Patergnani; Peter Ludewig; Katrin Lessmann; Tim Magnus; Ilaria Casetta; Maura Pugliatti; Paolo Pinton; Carlotta Giorgi
Published in: Biomedicines, Vol 9, Iss 169, p 169 (2021), Issue 22279059, 2021, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines9020169

Increase of Parkin and ATG5 plasmatic levels following perinatal hypoxic-ischemic encephalopathy

Author(s): Anna Tarocco , Giampaolo Morciano , Mariasole Perrone , Claudia Cafolla , Cristina Ferrè, Tiziana Vacca , Ginevra Pistocchi , Fabio Meneghin , Ilaria Cocchi , Gianluca Lista , Irene Cetin , Pantaleo Greco , Giampaolo Garani , Marcello Stella , Miria Natile , Gina Ancora, Immacolata Savarese , Francesca Campi , Iliana Bersani , Andrea Dotta , Eloisa Tiberi , Giovanni Vento , Elisabetta Chiodin , A
Published in: Scientific reports, 2022, ISSN 2045-2322
Publisher: Nature Publishing Group
DOI: 10.1038/s41598-022-11870-w

A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients

Author(s): Giampaolo Morciano , Gaia Pedriali , Massimo Bonora , Rita Pavasini , Elisa Mikus , Simone Calvi , Matteo Bovolenta , Magdalena Lebiedzinska-Arciszewska, Mirko Pinotti , Alberto Albertini , Mariusz R Wieckowski , Carlotta Giorgi , Roberto Ferrari , Lorenzo Galluzzi , Gianluca Campo , Paolo Pinton.
Published in: Cell reports, 2021, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.108983

Mitochondrial Control of Genomic Instability in Cancer.

Author(s): Massimo Bonora; Sonia Missiroli; Mariasole Perrone; Francesco Fiorica; Paolo Pinton; Carlotta Giorgi
Published in: Cancers, Vol 13, Iss 1914, p 1914 (2021), Issue 5, 2021, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13081914

Citrate Mediates Crosstalk between Mitochondria and the Nucleus to Promote Human Mesenchymal Stem Cell In Vitro Osteogenesis

Author(s): Claudia Morganti, Massimo Bonora, Saverio Marchi, Letizia Ferroni, Chiara Gardin, Mariusz R Wieckowski, Carlotta Giorgi, Paolo Pinton, Barbara Zavan
Published in: Cells, 2020, ISSN 2073-4409
Publisher: MDPI
DOI: 10.3390/cells9041034

The Role of Mitochondria in Inflammation: From Cancer to Neurodegenerative Disorders

Author(s): Sonia Missiroli; Ilaria Genovese; Mariasole Perrone; Bianca Vezzani; Veronica Angela Maria Vitto; Carlotta Giorgi
Published in: Journal of Clinical Medicine, Issue 1, 2020, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9030740

Mitophagy in Cardiovascular Diseases.

Author(s): Giampaolo Morciano; Simone Patergnani; Massimo Bonora; Gaia Pedriali; Anna Tarocco; Esmaa Bouhamida; Saverio Marchi; Gina Ancora; Gabriele Anania; Mariusz R. Wieckowski; Carlotta Giorgi; Paolo Pinton
Published in: Journal of Clinical Medicine, Issue 20770383, 2020, ISSN 2077-0383
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/jcm9030892

The LRRC8C-STING-p53 axis in T cells: A Ca2+ affair

Author(s): Sonia Missiroli; Carlotta Giorgi; Paolo Pinton
Published in: Crossref, Issue 2, 2022, ISSN 1532-1991
Publisher: Churchill Livingston
DOI: 10.1016/j.ceca.2022.102596

Calcium dysregulation in heart diseases: Targeting calcium channels to achieve a correct calcium homeostasis

Author(s): Giampaolo Morciano ,Alessandro Rimessi , Simone Patergnani , Veronica A M Vitto , Alberto Danese Asrat Kahsay , Laura Palumbo , Massimo Bonora , Mariusz R Wieckowski , Carlotta Giorgi , Paolo Pinton
Published in: Pharmacological research, 2022, ISSN 1096-1186
Publisher: Academic Press
DOI: 10.1016/j.phrs.2022.106119

Molecular Mechanisms of Autophagy in Cancer Development, Progression, and Therapy

Author(s): Veronica Angela Maria Vitto, Silvia Bianchin , Alicia Ann Zolondick , Giulia Pellielo , Alessandro Rimessi , Diego Chianese , Haining Yang , Michele Carbone , Paolo Pinton , Carlotta Giorgi , Simone Patergnani
Published in: Biomedicines, 2022, ISSN 2227-9059
Publisher: MDPI
DOI: 10.3390/biomedicines10071596

Pathological mitophagy disrupts mitochondrial homeostasis in Leber's hereditary optic neuropathy

Author(s): Alberto Danese, Simone Patergnani , Alessandra Maresca , Camille Peron , Andrea Raimondi , Leonardo Caporali , Saverio Marchi , Chiara La Morgia , Valentina Del Dotto , Claudia Zanna , Angelo Iannielli , Alice Segnali , Ivano Di Meo , Andrea Cavaliere , Magdalena Lebiedzinska-Arciszewska , Mariusz R Wieckowski , Andrea Martinuzzi , Milton N Moraes-Filho , Solange R Salomao , Adriana Berezovsky , R
Published in: Cell reports, 2022, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2022.111124

Mitochondrial P2X7 Receptor Localization Modulates Energy Metabolism Enhancing Physical Performance

Author(s): Alba Clara Sarti 1, Valentina Vultaggio-Poma 1, Simonetta Falzoni 1, Sonia Missiroli 1, Anna Lisa Giuliani 1, Paola Boldrini 2, Massimo Bonora 1, Francesco Faita 3, Nicole Di Lascio 3, Claudia Kusmic 3, Anna Solini 4, Salvatore Novello 5, Michele Morari 5, Marco Rossato 6, Mariusz R Wieckowski 7, Carlotta Giorgi 1, Paolo Pinton 1, Francesco Di Virgilio 1
Published in: Function (Oxford, England), 2021, ISSN 2633-8823
Publisher: Oxford University Press
DOI: 10.1093/function/zqab005

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