From mechanical control to shape-shifting in supramolecular biomaterials to guide stem cell fate

Project Information

SupraCTRL

Grant agreement ID: 853625

DOI

10.3030/853625

Project closed

EC signature date 14 May 2020

Start date 1 September 2020

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

UNIVERSITEIT LEIDEN
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

Covalent Network Formation Rate Controls Depletion‐Induced Supramolecular Assembly in Hybrid Double Network Hydrogels

Author(s): Mertcan Özel, Sebastian Novosedlik, Tingxian Liu, Lucía López‐Gandul, Heleen Duijs, Hari Veera Prasad Thelu, Ciqing Tong, Roxanne E. Kieltyka
Published in: Angewandte Chemie International Edition, Issue e8845737, 2026, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.8845737

Dynamic Exchange in 3D Cell Culture Hydrogels Based on Crosslinking of Cyclic Thiosulfinates

Author(s): Merel L. Janssen, Tingxian Liu, Mertcan Özel, Maaike Bril, Hari Veera Prasad Thelu, Roxanne E. Kieltyka
Published in: Angewandte Chemie International Edition, Issue 63, 2024, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202314738

Squaramide‐Based Supramolecular Materials Drive HepG2 Spheroid Differentiation

Author(s): Tingxian Liu, Linda van den Berk, Joeri A. J. Wondergem, Ciqing Tong, Markus C. Kwakernaak, Bas ter Braak, Doris Heinrich, Bob van de Water, Roxanne E. Kieltyka
Published in: Advanced Healthcare Materials, Issue 10, 2025, ISSN 2192-2640
Publisher: John Wiley and Sons Ltd
DOI: 10.1002/adhm.202001903

Hydrophobic Domain Modulation of Chemical Responsiveness in a Bolaamphiphile‐Based Supramolecular Monomer

Author(s): Sandeepa K. Vittala, Tingxian Liu, Suzanne van Zwol, Bence Fehér, Ilja K. Voets, Roxanne E. Kieltyka
Published in: ChemBioChem, Issue 26, 2026, ISSN 1439-4227
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/cbic.202400348

Spatial and Temporal Modulation of Cell Instructive Cues in a Filamentous Supramolecular Biomaterial

Author(s): Ciqing Tong, Joeri A. J. Wondergem, Marijn van den Brink, Markus C. Kwakernaak, Ying Chen, Marco M. R. M. Hendrix, Ilja K. Voets, Erik H. J. Danen, Sylvia Le Dévédec, Doris Heinrich, and Roxanne E.
Published in: ACS Applied Materials and Interfaces, Issue 14 ,15, 2022, Page(s) 17042-17054, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.1c24114