a novel drug for prevention and treatment peripheral neuropathy symptoms

Información del proyecto

MP-101

Identificador del acuerdo de subvención: 854931

DOI

10.3030/854931

Proyecto cerrado

Fecha de la firma de la CE 31 Enero 2019

Fecha de inicio 1 Enero 2019

Fecha de finalización 30 Abril 2019

Financiado con arreglo a

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Coste total

€ 71 429,00

Aportación de la UE

€ 50 000,00

Coordinado por

METYS PHARMACEUTICALS AG
Switzerland

Periodic Reporting for period 1 - MP-101 (a novel drug for prevention and treatment peripheral neuropathy symptoms)

Período documentado: 2019-01-01 hasta 2019-04-30

Resumen del contexto y de los objetivos generales del proyecto

There were over 18 million new cases of cancer worldwide in 2018, out of which about 3.7 million were in Europe. Up to 40% of all cancer patients develop chemotherapy-induced peripheral neuropathy (CIPN). CIPN is a condition that affects the peripheral nervous system, leading to long-lasting, painful, and difficult-to-treat symptoms. At present, only a few therapies are available for the treatment of peripheral neuropathy with moderately effectiveness, but none is specifically developed for CIPN and with substantial side effects for patients. Metys Pharmaceuticals Ltd. has developed MP-101 - a novel, non-sedating, painkiller for prevention and for treatment of CIPN-associated neuropathic pain.

Trabajo realizado desde el comienzo del proyecto hasta el final del período abarcado por el informe y los principales resultados hasta la fecha

From 1 January until 30 April 2019, Metys Pharmaceuticals Ltd. used Phase 1 funding to carry out an extensive study with the objective to identify the technical and business requirements of delivering a finished and legally approved commercial version of MP-101. From a technical point of view, Metys reviewed in detail the current stage of MP-101 and defined a sound development plan for its approval and commercialisation. From a business point of view, the Company performed a deep market analysis, verified its business model and established a sound go-to-market strategy.

Avances que van más allá del estado de la técnica e impacto potencial esperado (incluida la repercusión socioeconómica y las implicaciones sociales más amplias del proyecto hasta la fecha)

Metys’ novel drug aims at a clinical application in response to yet unanswered medical needs of cancer chemotherapy-induced peripheral neuropathy symptoms. So far, in fact there has been very limited progress in discovery of agents that show benefit in the treatment of CIPN. MP-101 has potential to become the first drug approved for the prevention and management of CIPN.

peripheral neutopathy