Descripción del proyecto
Un método diagnóstico innovador para la infertilidad
La infertilidad afecta a veinticinco millones de europeos. En multitud de ocasiones, la infertilidad, tanto femenina como masculina, se debe a trastornos genéticos. Como tal, la identificación de sus causas requiere una prueba genética para cerca del 35 % de las parejas en proceso de diagnóstico. Sin embargo, muchos factores dificultan la eficacia del análisis genético de la infertilidad y el conjunto del proceso diagnóstico. En este contexto, el proyecto financiado con fondos europeos One4Two creará el primer sistema integrado que proporciona un servicio de diagnóstico inclusivo para las parejas infértiles. Desde los análisis de laboratorio hasta el diagnóstico, solo se necesitará una única muestra de sangre. El objetivo del proyecto es optimizar el sistema con los usuarios finales, tomar las medidas necesarias para obtener los certificados requeridos, ampliar las capacidades y la comercialización, así como consolidar el modelo de negocio, la estrategia comercial y la fijación de precios.
Objetivo
Infertility is a disorder of the reproductive system which affects 25 million citizens in Europe, preventing them from fulfilling their desire to become a parent. To identify its causes, genetic testing is prescribed to around 35% of the couples under diagnosis, since several factors related to infertility have a genetic origin. However, the effectiveness of infertility genetic analysis and the whole diagnosis process are affected by several issues: an uncomprehensive approach to fertility genetic test, with just a handful of genetic diseases being investigated, each through a dedicated test; a fragmented and cumbersome genetic investigation process that negatively impacts on the couple, adding to the psychological distress caused by infertility, with several batteries of tests often in different laboratories, long diagnosis times and high costs; the lack of a specific genetic testing protocol and diagnosis report for infertility, which increases the workload for laboratories and complicates the diagnosis by gynecologists. KronosDNA has developed One4Two, the first integrated system that provides a comprehensive diagnostic service for the infertile couple, able to cover the whole diagnostic path from lab analysis (through a panel of reagents to analyse DNA through Next Generation Sequencing) to the diagnostic report (by means of a proprietary analysis software). One4Two, with just one blood sample, in 5 days and at an affordable price, provides a complete report on the mutations linked to infertility, probability scores for the transmission of inherited diseases, and the most suitable ART therapies to treat infertility. This is poised to reduce analysis workload, simplify diagnosis by the gynecologist and reduce time to pregnancy. During Phase 1 project, the system will be optimized with end-users to prepare the ground for the required certifications, upscaling and commercialization, by also consolidating the business model, the marketing strategy and the pricing.
Ámbito científico
Programa(s)
Convocatoria de propuestas
Consulte otros proyectos de esta convocatoriaConvocatoria de subcontratación
H2020-SMEInst-2018-2020-1
Régimen de financiación
SME-1 - SME instrument phase 1Coordinador
80133 NAPOLI
Italia
Organización definida por ella misma como pequeña y mediana empresa (pyme) en el momento de la firma del acuerdo de subvención.