CETOCOEN Excellence

Livrables

1st Regional and global engagement report

Regional stakeholders engagement Sciencetopolicy sciencetosociety engagement Networking

2nd Regional and global engagement report

Regional stakeholders engagement. Science-to-policy, science-to-society engagement. Networking.

Project website

Project website.

Publications

FireProtASR: A Web Server for Fully Automated Ancestral Sequence Reconstruction

Auteurs: Musil, M.; Khan; R. T.; Beier, A.; Stourac, J.; Konegger, H.; Damborsky, J.; Bednar, D.
Publié dans: Briefings in Bioinformatics, Numéro 14675463, 2021, ISSN 1467-5463
Éditeur: Oxford University Press
DOI: 10.1093/bib/bbaa337

Firefighters and the liver: Exposure to PFAS and PAHs in relation to liver function and serum lipids (CELSPAC-FIREexpo study)

Auteurs: PÁLEŠOVÁ, Nina, Lea MAITRE, Nikos STRATAKIS, Katarína ŘIHÁČKOVÁ, Aleš PINDUR, Jiří KOHOUTEK, Petr ŠENK, Anna BARTOŠKOVÁ, Petr GREGOR, Martine VRIJHEID and Pavel ČUPR
Publié dans: International Journal of Hygiene and Environmental Health, 2023, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2023.114215

Synthesis of Glycoluril Dimers with the Ability to Form Polymeric Self-Associates in Water

Auteurs: Jan Sokolov; Vladimír Šindelář
Publié dans: Chemistry; Volume 4; Numéro 3; Pages: 753-764, 2022, ISSN 2624-8549
Éditeur: MDPI
DOI: 10.3390/chemistry4030053

pyCaverDock: Python implementation of the popular tool for analysis of ligand transport with advanced caching and batch calculation support

Auteurs: VÁVRA, Ondřej, Jakub BERANEK, Jan ŠTOURAČ, Martin SURKOVSKY, Jiří FILIPOVIČ, Jiří DAMBORSKÝ, Jan MARTINOVIC and David BEDNÁŘ
Publié dans: Bioinformatics, 2023, ISSN 1367-4803
Éditeur: Oxford University Press
DOI: 10.1093/bioinformatics/btad443

Structure-Dependent Effects of Phthalates on Intercellular and Intracellular Communication in Liver Oval Cells

Auteurs: Lucie Čtveráčková, Daniel Jančula, Jan Raška, Pavel Babica, Iva Sovadinová
Publié dans: International Journal of Molecular Sciences, Numéro 21/17, 2020, Page(s) 6069, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms21176069

Cylindrospermopsin is effectively degraded in water by pulsed corona-like and dielectric barrier discharges

Auteurs: Marcel Schneider, Raphael Rataj, Juergen F. Kolb, Luděk Bláha
Publié dans: Environmental Pollution, Numéro 266, 2020, Page(s) 115423, ISSN 0269-7491
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2020.115423

Homeostatic model of human thermoregulation with bi-stability

Auteurs: Hajnova, V.; Zlamal, F.; Lenart, P.; Bienertova-Vasku, J.
Publié dans: Scientific Reports, Numéro 20452322, 2021, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-021-96280-0

Porphyrin as a versatile visible-light-activatable organic/metal hybrid photoremovable protecting group

Auteurs: Sekhar, A. R., Chitose, Y., Janoš, J., Dangoor, S. I., Ramundo, A., Satchi-Fainaro, R., Slavíček, P., Klán, P., & Weinstain, R.
Publié dans: Nature Communication, 2022, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-022-31288-2

Bioanalytical and chemical characterization of organic micropollutant mixtures in long-term exposed passive samplers from the Joint Danube Survey 4: Setting a baseline for water quality monitoring

Auteurs: SAUER, Pavel, Branislav VRANA, Beate I. ESCHER, Roman GRABIC, Zuzana TOUŠOVÁ, Martin KRAUSS, Peter C. VON DER OHE, Maria KOENIG, Katerina GRABICOVA, Petra MIKUŠOVÁ, Roman PROKEŠ, Jaromír SOBOTKA, Pavla FIALOVÁ, Jiří NOVÁK, Werner BRACK and Klára HILSCHEROVÁ
Publié dans: Environment International, 2023, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.107957

Using real-time ascertainment rate estimate from infection and hospitalization dataset for modeling the spread of infectious disease: COVID-19 case study in the Czech Republic

Auteurs: Lenka Přibylová; Veronika Eclerová; Ondřej Májek; Jiří Jarkovský; Tomáš Pavlík; Ladislav Dušek
Publié dans: PLoS ONE, 2023, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0287959

Cadmium exposure in adults across Europe: Results from the HBM4EU Studies 2014-2020

Auteurs: TRATNIK, Janja Snoj, David KOCMAN, Milena HORVAT, Anna-Maria ANDERSSON, Anders JUUL, Eva JACOBSEN, Kristin OLAFSDOTTIR, Jana KLÁNOVÁ, Lenka ANDRÝSKOVÁ, Beata JANASIK, Wojciech WASOWICZ, Natasa Janev HOLCER, Sonia NAMORADO, Ines COELHO, Loic RAMBAUD, Margaux RIOU, An VAN NIEUWENHUYSE, Brice APPENZELLER, Marike KOLOSSA-GEHRING, Till WEBER, Marta ESTEBAN-LOPEZ, Argelia CASTAN, Liese GILLES, Laura
Publié dans: INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH, 2022, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2022.114050

Sulfonothioated meso-Methyl BODIPY Shows Enhanced Uncaging Efficiency and Releases H2Sn

Auteurs: Lucie Wohlrábová; Jana Okoročenkova; Eduardo Palao; Erika Kužmová; Karel Chalupský; Petr Klán; Tomáš Slanina
Publié dans: Organic letters, 2023, ISSN 1523-7060
Éditeur: American Chemical Society
DOI: 10.1021/acs.orglett.3c02511

Recognition and coacervation of G-quadruplexes by a multifunctional disordered region in RECQ4 helicase

Auteurs: PAPAGEORGIOU, Anna, Michaela POSPÍŠILOVÁ, Jakub CIBULKA, Raghib ASHRAF, Christopher WAUDBY, Pavel KADEŘÁVEK, Volha MAROZ, Karel KUBÍČEK, Zbyněk PROKOP, Lumír KREJČÍ and Konstantinos TRIPSIANES
Publié dans: Nature Communications, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-42503-z

Birth outcomes, puberty onset, and obesity as long-term predictors of biological aging in young adulthood

Auteurs: JÁNI, Martin, Lenka KOTAČKOVÁ, Pavel PILER, Lenka ANDRÝSKOVÁ, Milan BRÁZDIL and Klára MAREČKOVÁ
Publié dans: Frontiers in Nutrition, 2023, ISSN 2296-861X
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2022.1100237

Deciphering Enzyme Mechanisms with Engineered Ancestors and Substrate Analogues

Auteurs: GAO, Tadeja, Jiří DAMBORSKÝ, Yves L. JANIN and Martin MAREK
Publié dans: ChemCatChem, 2023, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202300745

Assessment of exposure to pesticide mixtures in five European countries by a harmonized urinary suspect screening approach

Auteurs: OTTENBROS, Ilse, Erik LEBRET, Carolin HUBER, Arjen LOMMEN, Jean-Philippe ANTIGNAC, Pavel ČUPR, Libor ŠULC, Ondřej MIKEŠ, Tamas SZIGETI, Szilvia KOZEPESY, Inese MARTINSONE, Zanna MARTINSONE, Lasma AKULOVA, Olga PARDO, Sandra F. FERNANDEZ, Clara COSCOLLA, Susana PEDRAZA-DIAZ, Martin KRAUSS, Laurent DEBRAUWER, Kevin WAGNER, Rosalie NIJSSEN, Hans MOL, Chiara Maria VITALE, Jana KLÁNOVÁ, Borja Gar
Publié dans: International Journal of Hygiene and Environmental Health, 2023, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2022.114105

CYP2C19 Gene Profiling as a Tool for Personalized Stress Ulcer Prophylaxis With Proton Pump Inhibitors in Critically Ill Patients - Recommendations Proposal

Auteurs: Petra Bořilová Linhartová; Ondřej Zendulka; Jaroslav Janošek; Natálie Mlčůchová; Michaela Cvanová; Zdeněk Daněk; Radek Kroupa; Ladislava Bartošová; Břetislav Lipový
Publié dans: Frontiers in Medicine, 2022, ISSN 2296-858X
Éditeur: Frontiers Media
DOI: 10.3389/fmed.2022.854280

Denitrification Assays for Testing Effects of Xenobiotics on Aquatic Denitrification and Their Degradation in Aquatic Environments

Auteurs: PANIKOVA, Kristina, Gabriele WEIGELHOFER, Zuzana BÍLKOVÁ and Jitka MALA
Publié dans: Water, 2023, ISSN 2073-4441
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/w15142536

Visible-to-NIR-Light Activated Release: From Small Molecules to Nanomaterials

Auteurs: Roy Weinstain, Tomáš Slanina, Dnyaneshwar Kand, Petr Klán
Publié dans: Chemical Reviews, Numéro 120/24, 2020, Page(s) 13135-13272, ISSN 0009-2665
Éditeur: American Chemical Society
DOI: 10.1021/acs.chemrev.0c00663

Unlocking India’s Potential in Managing Endocrine-Disrupting Chemicals (EDCs): Importance, Challenges, and Opportunities

Auteurs: Brij Mohan Sharma; Martin Scheringer; Paromita Chakraborty; Girija K. Bharat; Eirik Hovland Steindal; Leonardo Trasande; Luca Nizzetto
Publié dans: Exposure Health, 2022, ISSN 2451-9766
Éditeur: Springer Verlag
DOI: 10.1007/s12403-022-00519-8

Socioeconomic characteristics, family structure and trajectories of children’s psychosocial problems in a period of social transition

Auteurs: Daniela Kuruczova, Jana Klanova, Jiri Jarkovsky, Hynek Pikhart, Julie Bienertova-Vasku
Publié dans: PLOS ONE, Numéro 15/6, 2020, Page(s) e0234074, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0234074

Structural and catalytic effects of surface loop-helix transplantation within haloalkane dehalogenase family

Auteurs: Martin Marek, Radka Chaloupkova, Tatyana Prudnikova, Yukari Sato, Pavlina Rezacova, Yuji Nagata, Ivana Kuta Smatanova, Jiri Damborsky
Publié dans: Computational and Structural Biotechnology Journal, Numéro 18, 2020, Page(s) 1352-1362, ISSN 2001-0370
Éditeur: Elsevier
DOI: 10.1016/j.csbj.2020.05.019

Highlighting the gaps in hazard and risk assessment of unregulated Endocrine Active Substances in surface waters: retinoids as a European case study.

Auteurs: Kubickova, B.; Ramwell, C.; Hilscherova, K.; Jacobs, M. N.
Publié dans: Environmental Sciences Europe, Numéro 21904707, 2021, ISSN 2190-4707
Éditeur: Springer Verlag
DOI: 10.1186/s12302-020-00428-0

Development of historic monthly land use regression models of SO2, NOx and suspended particulate matter for birth cohort ELSPAC

Auteurs: MIKEŠ, Ondřej, Ondřej SÁŇKA, Aneta RAFAJOVÁ, Jelle VLAANDEREN, Jie CHEN, Gerard HOEK, Jana KLÁNOVÁ and Pavel ČUPR
Publié dans: Atmospheric Environment, 2023, ISSN 1352-2310
Éditeur: Elsevier BV
DOI: 10.1016/j.atmosenv.2023.119688

Effect of fixed orthodontic appliances on gingival status and oral microbiota: a pilot study

Auteurs: Zuzana Marincak Vrankova; Margarita Rousi; Michaela Cvanova; Daniela Gachova; Filip Ruzicka; Veronika Hola; Jan Lochman; Lydie Izakovicova Holla; Alena Brysova; Petra Borilova Linhartova
Publié dans: BMC Oral Health, 2022, ISSN 1472-6831
Éditeur: BioMed Central
DOI: 10.1186/s12903-022-02511-9

Epigenetic clock as a correlate of anxiety

Auteurs: Klára Marečková, Anna Pačínková, Anja Klasnja, Jean Shin, Lenka Andrýsková, Kateřina Stano-Kozubík, Zdenka Pausová, Milan Brázdil, Tomáš Paus
Publié dans: NeuroImage: Clinical, Numéro 28, 2020, Page(s) 102458, ISSN 2213-1582
Éditeur: Elsevier BV
DOI: 10.1016/j.nicl.2020.102458

Application of 96-well plate SPE method for analysis of persistent organic pollutants in low volume blood serum samples.

Auteurs: Palát, J., Kukučka, P., Codling, G. P., Price, E. J., Janků, P., & Klánová, J.
Publié dans: Chemosphere, Numéro 00456535, 2022, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2021.132300

Determinants of depressive symptoms increase in older persons during the COVID-19 pandemic: evidence from Czech cohort study using repeated assessments

Auteurs: DALECKÁ, Andrea, Hynek PIKHART, Anna BARTOŠKOVÁ, Naděžda ČAPKOVÁ and Martin BOBÁK
Publié dans: Journal of Epidemiology and Community Health, 2023, ISSN 0143-005X
Éditeur: British Medical Association
DOI: 10.1136/jech-2022-219412

Candida species and selected behavioral factors co-associated with severe early childhood caries: Case-control study

Auteurs: Michaela Cvanova; Filip Ruzicka; Martina Kukletova; Bretislav Lipovy; Daniela Gachova; Lydie Izakovicova Holla; Zdenek Danek; Veronika Hola; Michaela Bartosova; Jiri Jarkovsky; Ladislav Dusek; Petra Borilova Linhartova
Publié dans: Frontiers in Cellular and Infection Microbiology, 2022, ISSN 2235-2988
Éditeur: Frontiers Media S. A.
DOI: 10.3389/fcimb.2022.943480

Association of Picky Eating with Weight and Height—The European Longitudinal Study of Pregnancy and Childhood (ELSPAC–CZ)

Auteurs: Grulichova, M., Kuruczova, D., Svancara, J., Pikhart, H., & Bienertova-Vasku, J.
Publié dans: Nutrients, Numéro 20726643, 2022, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14030444

Substrate Inhibition by the Blockage of Product Release and Its Control by Tunnel Engineering

Auteurs: Piia Kokkonen; Andy Beier; Stanislav Mazurenko; Jiri Damborsky; David Bednar; Zbynek Prokop
Publié dans: RSC Chemical Biology, Numéro 26330679, 2021, ISSN 2633-0679
Éditeur: Royal Society of Chemistry
DOI: 10.26434/chemrxiv.13311614.v1

Pesticides in Small Agricultural Catchments in the Czech Republic

Auteurs: Jana Konečná; Antonín Zajíček; Milan Sáňka; Taťána Halešová; Markéta Kaplická; Eva Nováková
Publié dans: Journal of Ecological Engineering, Numéro 1, 2023, ISSN 2299-8993
Éditeur: Polskie Towarzystwo Inzynierii Ekologicznej
DOI: 10.12911/22998993/157471

Harmonization of Human Biomonitoring Studies in Europe: Characteristics of the HBM4EU-Aligned Studies Participants

Auteurs: Gilles, L.; Govarts, E.; Rodriguez Martin, L.; Andersson, A.-M.; Appenzeller, B.M.R.; Barbone, F.; Castaño, A.; Coertjens, D.; Den Hond, E.; Dzhedzheia, V.; Eržen, I.; López, M.E.; Fábelová, L.; Fillol, C.; Franken, C.; Frederiksen, H.; Gabriel, C.; Haug, L.S.; Horvat, M.; Halldórsson, T.I.; Janasik, B.; Holcer, N.J.; Kakucs, R.; Karakitsios, S.; Katsonouri, A.; Klánová, J.; Kold-Jensen, T
Publié dans: International Journal of Environmental Research and Public Health, Numéro 16604601, 2022, ISSN 1660-4601
Éditeur: MDPI
DOI: 10.3390/ijerph19116787

Oxygenated and Nitrated Polycyclic Aromatic Hydrocarbons in Ambient Air—Levels, Phase Partitioning, Mass Size Distributions, and Inhalation Bioaccessibility

Auteurs: Gerhard Lammel, Zoran Kitanovski, Petr Kukučka, Jiří Novák, Andrea M. Arangio, Garry P. Codling, Alexander Filippi, Jan Hovorka, Jan Kuta, Cecilia Leoni, Petra Příbylová, Roman Prokeš, Ondřej Sáňka, Pourya Shahpoury, Haijie Tong, Marco Wietzoreck
Publié dans: Environmental Science & Technology, Numéro 54/5, 2020, Page(s) 2615-2625, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.9b06820

Osteocalcin levels decrease during the treatment of an acute depressive episode

Auteurs: BARTEČKŮ, Elis, Jana HOŘÍNKOVÁ, Pavel KŘENEK, Alena DAMBORSKÁ, Josef TOMANDL, Marie TOMANDLOVÁ, Jan KUČERA, Jana KUČEROVÁ and Julie DOBROVOLNÁ.
Publié dans: Frontiers in Psychiatry, 2022, ISSN 1664-0640
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fpsyt.2022.893012

Genotoxic effects of transboundary pollutants in Pinus mugo in the high mountain habitats

Auteurs: KLEMMOVÁ GREGUŠKOVÁ, Eva, Daniel MIHALIK, Jan KRAIC, Michaela MRKVOVA, Jozef SOKOL, Petr GREGOR, Aneta RAFAJOVÁ and Pavel ČUPR
Publié dans: Ecological indicators, 2022, ISSN 1470-160X
Éditeur: Elsevier BV
DOI: 10.1016/j.ecolind.2022.109009

Geometric Control of Cell Behavior by Biomolecule Nanodistribution

Auteurs: POSPÍŠIL, Jakub, Milos HRABOVSKY, Dáša BOHAČIAKOVÁ, Zuzana HOVADKOVA, Miroslav JURÁSEK, Jarmila MLČOUŠKOVÁ, Kamil PARUCH, Šárka NEVOLOVÁ, Jiří DAMBORSKÝ, Aleš HAMPL and Josef JAROŠ
Publié dans: ACS BIOMATERIALS SCIENCE & ENGINEERING, 2022, ISSN 2373-9878
Éditeur: AMER CHEMICAL SOC
DOI: 10.1021/acsbiomaterials.2c00650

From science to policy: How European HBM indicators help to answer policy questions related to phthalates and DINCH exposure

Auteurs: GEROFKE, Antje, Madlen DAVID, Phillipp SCHMIDT, Joana Lobo VICENTE, Jurgen BUEKERS, Liese GILLES, Ann COLLES, Jos BESSEMS, Michiel BASTIAENSEN, Adrian COVACI, Den Hond ELLY, Gudrun KOPPEN, Michelle LAEREMANS, Veerle J. VERHEYEN, Milena CERNA, Jana KLÁNOVÁ, Andrea KRSKOVA, Martin ZVONAŘ, Lisbeth E. KNUDSEN, Holger M. KOCH, Tina Kold JENSEN, Loic RAMBAUD, Margaux RIOU, Nina VOGEL, Catherine GABRI
Publié dans: International Journal of Hygiene and Environmental Health, 2023, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2022.114073

Effects of Dietary Zinc and/or an Herbal Mixture on Intestinal Microbiota and Barrier Integrity in Lambs.

Auteurs: BUJŇÁKOVÁ, Dobroslava, Katarína KUCKOVÁ, Zora VÁRADYOVÁ, Iveta PLACHÁ, Viola STROMPFOVÁ, Jan BÖHM, Lenka KOSEČKOVÁ MICENKOVÁ and Klaudia ČOBANOVÁ.
Publié dans: Agriculture, 2023, ISSN 2077-0472
Éditeur: MDPI
DOI: 10.3390/agriculture13091819

Cyanobacterial Harmful Bloom Lipopolysaccharides Induce Pro-Inflammatory Effects in Immune and Intestinal Epithelial Cells In Vitro

Auteurs: SKOČKOVÁ, Veronika, Ondřej VAŠÍČEK, Eliška SYCHROVÁ, Iva SOVADINOVÁ, Pavel BABICA and Lenka ŠINDLEROVÁ
Publié dans: Toxins, 2023, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins15030169

Personal care product use and lifestyle affect phthalate and DINCH metabolite levels in teenagers and young adults

Auteurs: STUCHLÍK FIŠEROVÁ, Petra, Lisa Emily MELYMUK, Klára KOMPRDOVÁ, Elena DOMINGUEZ ROMERO, Martin SCHERINGER, Jiří KOHOUTEK, Petra PŘIBYLOVÁ, Lenka ANDRÝSKOVÁ, Pavel PILER, Holger M. KOCH, Martin ZVONAŘ, Marta ESTEBAN-LOPEZ, Argelia CASTANO and Jana KLÁNOVÁ
Publié dans: Environmental Research, 2022, ISSN 0013-9351
Éditeur: Academic Press
DOI: 10.1016/j.envres.2022.113675

EnzymeMiner: automated mining of soluble enzymes with diverse structures, catalytic properties and stabilities

Auteurs: Jiri Hon, Simeon Borko, Jan Stourac, Zbynek Prokop, Jaroslav Zendulka, David Bednar, Tomas Martinek, Jiri Damborsky
Publié dans: Nucleic Acids Research, Numéro 48/W1, 2020, Page(s) W104-W109, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkaa372

Polycyclic aromatic hydrocarbons (PAHs) and their alkylated, nitrated and oxygenated derivatives in the atmosphere over the Mediterranean and Middle East seas

Auteurs: WIETZORECK, Marco, Marios KYPRIANOU, Benjamin A. MUSA BANDOWE, Siddika CELIK, John N. CROWLEY, Frank DREWNICK, Philipp EGER, Nils FRIEDRICH, Minas IAKOVIDES, Petr KUKUČKA, Jan KUTA, Barbora NEŽIKOVÁ, Petra POKORNA, Petra PŘIBYLOVÁ, Roman PROKEŠ, Roland ROHLOFF, Ivan TADIC, Sebastian TAUER, Jake WILSON, Hartwig HARDER, Jos LELIEVELD, Ulrich POESCHL, Euripides G STEPHANOU and Gerhard LAMMEL
Publié dans: Atmospheric Chemistry and Physics, 2022, ISSN 1680-7316
Éditeur: European Geophysical Society
DOI: 10.5194/acp-22-8739-2022

Screening of World Approved Drugs against Highly Dynamical Spike Glycoprotein of SARS-CoV-2 using CaverDock and Machine Learning

Auteurs: Gaspar Pinto; Gaspar Pinto; Ondrej Vavra; Ondrej Vavra; Sérgio M. Marques; Sérgio M. Marques; Jiri Filipovic; David Bednar; David Bednar; Jiri Damborsky; Jiri Damborsky
Publié dans: Computational and Structural Biotechnology Journal, Numéro 20010370, 2021, ISSN 2001-0370
Éditeur: ELSEVIER
DOI: 10.1016/j.csbj.2021.05.043

Nitro- and oxy-PAHs in grassland soils from decade-long sampling in central Europe

Auteurs: WIETZORECK, M., B.A.M. BANDOWE, Jakub HOFMAN, Jakub MARTINÍK, Barbora NEŽIKOVÁ, Petr KUKUČKA, Petra PŘIBYLOVÁ and Gerhard LAMMEL
Publié dans: ENVIRONMENTAL GEOCHEMISTRY AND HEALTH, 2022, ISSN 0269-4042
Éditeur: Kluwer Academic Publishers
DOI: 10.1007/s10653-021-01066-y

The exposure of Czech firefighters to perfluoroalkyl substances and polycyclic aromatic hydrocarbons: CELSPAC – FIREexpo case-control human biomonitoring study

Auteurs: ŘIHÁČKOVÁ, Katarína, Aleš PINDUR, Klára KOMPRDOVÁ, Nina PÁLEŠOVÁ, Jiří KOHOUTEK, Petr ŠENK, Jana NAVRÁTILOVÁ, Lenka ANDRÝSKOVÁ, Ludmila ŠEBEJOVÁ, Richard HŮLEK, Mazen ISMAEL and Pavel ČUPR
Publié dans: SCIENCE OF THE TOTAL ENVIRONMENT, 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.163298

Human Infections by Wohlfahrtiimonas chitiniclastica: A Mini-Review and the First Report of a Burn Wound Infection after Accidental Myiasis in Central Europe

Auteurs: Martin Hladík; Bretislav Lipovy; Bretislav Lipovy; Yvona Kaloudová; Markéta Hanslianová; Ivana Vitkova; Tereza Deissová; Tomas Kempny; Martin Svoboda; Zdenek Kala; Pavel Brychta; Petra Borilova Linhartova
Publié dans: Microorganisms, Vol 9, Iss 1934, p 1934 (2021), Numéro 20762607, 2021, ISSN 2076-2607
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/microorganisms9091934

Evaluation of Microbiome-Host Relationships in the Zebrafish Gastrointestinal System Reveals Adaptive Immunity Is a Target of Bis(2-ethylhexyl) Phthalate (DEHP) Exposure

Auteurs: Ondrej Adamovsky, Amanda N. Buerger, Hana Vespalcova, Shahadur R. Sohag, Amy T. Hanlon, Pamela E. Ginn, Serena L. Craft, Stanislav Smatana, Eva Budinska, Maria Persico, Joseph H. Bisesi, Christopher J. Martyniuk
Publié dans: Environmental Science & Technology, Numéro 54/9, 2020, Page(s) 5719-5728, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.0c00628

A comparative study of synthetic winged peptides for absolute protein quantification

Auteurs: Eliska Benesova; Veronika Vidova; Zdenek Spacil
Publié dans: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021), Numéro 01604120, 2021, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1038/s41598-021-90087-9

Bile Acids Transporters of Enterohepatic Circulation for Targeted Drug Delivery

Auteurs: Durník, R., Šindlerová, L., Babica, P., & Jurček, O.
Publié dans: Molecules, 27(9), 2961, 2022, ISSN 1420-3049
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/molecules27092961

Disentangled Autoencoder for Cross-Stain Feature Extraction in Pathology Image Analysis

Auteurs: Helge Hecht, Mhd Hasan Sarhan, Vlad Popovici
Publié dans: Applied Sciences, Numéro 10/18, 2020, Page(s) 6427, ISSN 2076-3417
Éditeur: Applied Sciences
DOI: 10.3390/app10186427

Investigation of SARS-CoV-2 seroprevalence in relation to natural infection and vaccination between October 2020 and September 2021 in the Czech Republic: a prospective national cohort study

Auteurs: THON, Vojtěch, Pavel PILER, Tomáš PAVLÍK, Lenka ANDRÝSKOVÁ, Kamil DOLEŽEL, David KOSTKA, Hynek PIKHART, Martin BOBÁK and Jana KLÁNOVÁ
Publié dans: BMJ Open, 2023, ISSN 2044-6055
Éditeur: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-068258

Identification of Real-Life Mixtures Using Human Biomonitoring Data: A Proof of Concept Study

Auteurs: MARTIN, Laura Rodriguez, Ilse OTTENBROS, Nina VOGEL, Marike KOLOSSA-GEHRING, Phillipp SCHMIDT, Katarína ŘIHÁČKOVÁ, Julia Molina MIGUEL, Elena VAREA-JIMENEZ, Eva GOVARTS, Susana PEDRAZA-DIAZ, Erik LEBRET, Jelle VLAANDEREN and Mirjam LUIJTEN
Publié dans: Toxics, 2023, ISSN 2305-6304
Éditeur: MDPI
DOI: 10.3390/toxics11030204

Longitudinal study of epigenetic aging and its relationship with brain aging and cognitive skills in young adulthood

Auteurs: MAREČKOVÁ, Klára, Anna PAČÍNKOVÁ, Radek MAREČEK, Ludmila ŠEBEJOVÁ, Lydie IZAKOVIČOVÁ HOLLÁ, Jana KLÁNOVÁ, Milan BRÁZDIL and Yuliya S. NIKOLOVA
Publié dans: Frontiers in aging neuroscience, 2023, ISSN 1663-4365
Éditeur: Frontiers Research Foundation
DOI: 10.3389/fnagi.2023.1215957

Rapid extraction and analysis of oxidative stress and DNA damage biomarker 8-hydroxy-2 '-deoxyguanosine (8-OHdG) in urine: Application to a study with pregnant women.

Auteurs: BLÁHOVÁ, Lucie, Tomáš JANOŠ, Vicente MUSTIELES, Andrea RODRIGUEZ-CARRILLO, Mariana F. FERNANDEZ and Luděk BLÁHA.
Publié dans: International Journal of Hygiene and Environmental Health, 2023, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2023.114175

Has Regulatory Action Reduced Human Exposure to Flame Retardants?

Auteurs: VAN DER SCHYFF, Veronica, Jiří KALINA, Annalisa ABBALLE, Anna Laura IAMICELI, Eva GOVARTS and Lisa Emily MELYMUK
Publié dans: ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.3c02896

Human Exposure to Pesticides in Dust from Two Agricultural Sites in South Africa

Auteurs: DEGRENDELE, Céline, Roman PROKEŠ, Petr ŠENK, Simona Rozárka JÍLKOVÁ, Jiří KOHOUTEK, Lisa Emily MELYMUK, Petra PŘIBYLOVÁ, Mohamed Aqiel DALVIE, Martin ROOSLI, Jana KLÁNOVÁ and Samuel FUHRIMANN
Publié dans: Toxics, 2023, ISSN 2305-6304
Éditeur: MDPI
DOI: 10.3390/toxics10100629

Copper Oxide Nanoparticles Stimulate the Immune Response and Decrease Antioxidant Defense in Mice After Six-Week Inhalation

Auteurs: TULINSKA, Jana, Miroslava Lehotska MIKUSOVA, Aurelia LISKOVA, Milena BUSOVA, Vlasta MASANOVA, Iveta UHNAKOVA, Eva ROLLEROVA, Radka ALACOVA, Zora KRIVOSIKOVA, Ladislava WSOLOVA, Maria DUSINSKA, Mira HORVATHOVA, Michaela SZABOVA, Norbert LUKAN, Martina STUCHLIKOVA, Daniel KUBA, Zbynek VECERA, Pavel COUFALIK, Kamil KRUMAL, Lukas ALEXA, Lucie VRLIKOVA, Marcela BUCHTOVÁ, Jana DUMKOVÁ, Pavel PILER, Vo
Publié dans: Frontiers in Immunology, 2022, ISSN 1664-3224
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2022.874253

Disease network data for the pesticide fipronil in rat dopamine cells

Auteurs: Souders, C.L.; Rushin, A.; Sanchez, C.L.; Toth, D.; Adamovsky, O.; Martyniuk, C.J.
Publié dans: Data in Brief, 2021, ISSN 2352-3409
Éditeur: Elsevier BV
DOI: 10.1016/j.dib.2021.107299

Time-trends in human urinary concentrations of phthalates and substitutes DEHT and DINCH in Asian and North American countries (2009-2019)

Auteurs: DOMINGUEZ ROMERO, Elena, Klára KOMPRDOVÁ, Jiří KALINA, Jos BESSEMS, Spyros KARAKITSIOS, Dimosthenis A. SARIGIANNIS and Martin SCHERINGER
Publié dans: JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 2023, ISSN 1559-0631
Éditeur: Nature Publishing Group
DOI: 10.1038/s41370-022-00441-w

Replacement Flame-Retardant 2-Ethylhexyldiphenyl Phosphate (EHDPP) Disrupts Hepatic Lipidome: Evidence from Human 3D Hepatospheroid Cell Culture

Auteurs: NEGI, Chander Kant, Darshak Chandulal GADARA, Jiří KOHOUTEK, Lola Murielle BAJARD ÉP.ESNER, Zdeněk SPÁČIL and Luděk BLÁHA
Publié dans: ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2023, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.2c03998

Lack of Association between Epidermal Growth Factor or Its Receptor and Reflux Esophagitis, Barrett’s Esophagus, and Esophageal Adenocarcinoma: A Case-Control Study

Auteurs: Tereza Deissova; Michaela Cvanova; Zdenek Kala; Zuzana Jiraskova Zakostelska; Jiri Dolina; Lumir Kunovsky; Radek Kroupa; Zdenek Pavlovsky; Bretislav Lipovy; Zdenek Danek; Lydie Izakovicova Holla; Ondrej Urban; Vit Navratil; Robert Lischke; Tomas Harustiak; Tomas Grolich; Vladimir Prochazka; Ondrej Slaby; Petra Borilova Linhartova
Publié dans: Disease Markers, 2022, ISSN 0278-0240
Éditeur: IOS Press
DOI: 10.1155/2022/8790748

Advancing Enzyme's Stability and Catalytic Efficiency through Synergy of Force-Field Calculations, Evolutionary Analysis, and Machine Learning

Auteurs: KUNKA, Antonín, Sérgio Manuel MARQUES, Martin HAVLÁSEK, Michal VAŠINA, Nikola VELÁTOVÁ, Lucia CENGELOVÁ, David KOVÁŘ, Jiří DAMBORSKÝ, Martin MAREK, David BEDNÁŘ and Zbyněk PROKOP
Publié dans: ACS Catalysis, 2023, ISSN 2155-5435
Éditeur: American Chemical Society
DOI: 10.1021/acscatal.3c02575

Learning mitigates genetic drift

Auteurs: Peter Lenart; Julie Bienertová-Vašků; Luděk Berec
Publié dans: Nature Scientific Reports, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-24748-8

"Parabens and antimicrobial compounds in conventional and ""green"" personal care products"

Auteurs: Veronica van der Schyff; Lenka Suchánková; Katerina Kademoglou; Lisa Melymuk; Jana Klánová
Publié dans: Chemosphere, Numéro 00456535, 2022, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2022.134019

Spatial and Temporal Trends of Persistent Organic Pollutants across Europe after 15 Years of MONET Passive Air Sampling

Auteurs: Kevin B. White; Jiří Kalina; Martin Scheringer; Petra Přibylová; Petr Kukučka; Jiří Kohoutek; Roman Prokeš; Jana Klánová
Publié dans: ENVIRONMENTAL SCIENCE & TECHNOLOGY, Numéro 1, 2023, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.3c00796

Proposals of guidance values for surface contamination by antineoplastic drugs based on long term monitoring in Czech and Slovak hospitals and pharmacies.

Auteurs: BLÁHOVÁ, Lucie, Luděk BLÁHA, Lenka DOLEŽALOVÁ, Jan KUTA and Tereza HOJDAROVÁ.
Publié dans: Frontiers in Public Health, 2023, ISSN 2296-2565
Éditeur: Frontiers
DOI: 10.3389/fpubh.2023.1235496

Evaluation of Staphylococcus aureus growth and staphylococcal enterotoxin production in delicatessen and fine bakery products

Auteurs: Lenka Necidová; Šárka Bursová; Danka Haruštiaková; Kateřina Bogdanovičová
Publié dans: Acta veterinaria (Brno), Numéro 2, 2022, ISSN 0001-7213
Éditeur: University of Veterinary and Pharmaceutical Sciences
DOI: 10.2754/avb202291040417

Advanced oxidation processes for the removal of cyanobacterial toxins from drinking water

Auteurs: Marcel Schneider, Luděk Bláha
Publié dans: Environmental Sciences Europe, Numéro 32/1, 2020, ISSN 2190-4707
Éditeur: Springer Verlag
DOI: 10.1186/s12302-020-00371-0

City-scale assessment of long-term air quality impacts on the respiratory and cardiovascular health

Auteurs: ŠULC, Libor, Petr GREGOR, Jiří KALINA, Ondřej MIKEŠ, Tomáš JANOŠ and Pavel ČUPR
Publié dans: Frontiers in Public Health, 2022, ISSN 2296-2565
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fpubh.2022.1006536

Effects of pesticide exposure on oxidative stress and DNA methylation urinary biomarkers in Czech adults and children from the CELSPAC-SPECIMEn cohort

Auteurs: JANOŠ, Tomáš, Ilse OTTENBROS, Lucie BLÁHOVÁ, Petr ŠENK, Libor ŠULC, Nina PÁLEŠOVÁ, Jessica SHEARDOVÁ, Jelle VLAANDEREN and Pavel ČUPR
Publié dans: Environmental Research, 2023, ISSN 0013-9351
Éditeur: Academic Press
DOI: 10.1016/j.envres.2023.115368

16S rRNA gene primer choice impacts off-target amplification in human gastrointestinal tract biopsies and microbiome profiling

Auteurs: DEISSOVÁ, Tereza, Martina ZAPLETALOVÁ, Lumír KUNOVSKÝ, Radek KROUPA, Tomáš GROLICH, Zdeněk KALA, Petra BOŘILOVÁ LINHARTOVÁ and Jan LOCHMAN
Publié dans: Nature Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-39575-8

Association Between Parental Supply of Alcohol and Later Adolescent Alcohol Use in a Highly Permissive Context

Auteurs: KŠIŇAN, Albert, Gabriela KŠIŇANOVÁ, Eliška HREŽOVÁ, Lenka ANDRÝSKOVÁ, Hynek PIKHART and Martin BOBÁK
Publié dans: Journal of Studies on Alcohol and Drugs, 2023, ISSN 1937-1888
Éditeur: Center of Alcohol Studies, Rutgers, The State University of New Jersey
DOI: 10.15288/jsad.21-00437

Socioeconomic position over the life course and impaired lung function of older adults in Central and Eastern Europe: the HAPIEE study

Auteurs: QUISPE HARO, Consuelo, Andrzej PAJAK, Abdonas TAMOSIUNAS, Nadezda CAPKOVA, Martin BOBÁK and Hynek PIKHART
Publié dans: Journal of Epidemiology and Community Health, 2023, ISSN 0143-005X
Éditeur: British Medical Association
DOI: 10.1136/jech-2022-219348

Comparability of semivolatile organic compound concentrations from co-located active and passive air monitoring networks in Europe

Auteurs: Jiří Kalina; Kevin B. White; Martin Scheringer; Petra Přibylová; Petr Kukučka; Ondřej Audy; Jakub Martiník; Jana Klánová
Publié dans: Environmental Science: Processes & Impacts, 24(6), 898–909., Numéro 20507887, 2022, ISSN 2050-7887
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d2em00007e

Comparison of social gradient in cardiometabolic health in Czechia and Venezuela: a cross-sectional study.

Auteurs: Bartoskova Polcrova, A., Nieto-Martinez, R., Mechanick, J. I., Maranhao Neto, G. A., Infante-Garcia, M. M., Pikhart, H., Bobak, M., Medina-Inojosa, J., & Gonzalez-Rivas, J. P.
Publié dans: BMJ Open, 2023, ISSN 2044-6055
Éditeur: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-069077

Application of AOPs to assist regulatory assessment of chemical risks – Case studies, needs and recommendations.

Auteurs: Lola Bajard, Ondrej Adamovsky, Karine Audouze, Kirsten Baken, Robert Barouki, Joost B. Beltman, Anna Beronius, Eva Cecilie Bonefeld-Jørgensen, German Cano-Sancho, Milo L. de Baat, Filippo Di Tillio, Mariana F. Fernández, Rex E. FitzGerald, Claudia Gundacker, Antonio F. Hernández, Klara Hilscherova, Spyros Karakitsios, Eliska Kuchovska, Manhai Long, Mirjam Luijten, Sanah Majid, Philip Marx-Stoel
Publié dans: Environmental Research, 2023, ISSN 0013-9351
Éditeur: Academic Press
DOI: 10.1016/j.envres.2022.114650

Merging the exposome into an integrated framework for “omics” sciences

Auteurs: Price, E. J., Vitale, C. M., Miller, G. W., David, A., Barouki, R., Audouze, K., Walker, D. I., Antignac, J.-P., Coumoul, X., Bessonneau, V., & Klánová, J.
Publié dans: IScience, Numéro 25890042, 2022, ISSN 2589-0042
Éditeur: CELL PRESS
DOI: 10.1016/j.isci.2022.103976

Persistent Problem: Global Challenges to Managing PCBs

Auteurs: MELYMUK, Lisa Emily, Jonathan BLUMENTHAL, Ondřej SÁŇKA, Adriana SHU-YIN, Veena SINGLA, Kateřina ŠEBKOVÁ, Kristi Pullen FEDINICK and Miriam Leah DIAMOND
Publié dans: ENVIRONMENTAL SCIENCE & TECHNOLOGY, 2022, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.2c01204

Birth weight rather than birth length is associated with childhood behavioural problems in a Czech ELSPAC cohort.

Auteurs: Rackova, L.; Kuruczova, D.; Jarkovsky, J.; Bienertova-Vasku, J.
Publié dans: PLOS ONE, Numéro 19326203, 2021, ISSN 1932-6203
Éditeur: Public Library of Science
DOI: 10.1371/journal.pone.0253607

Educational gradients in all-cause mortality in two cohorts in the Czech Republic during the early stage of the postcommunist transition

Auteurs: PAULS, Ceciel, Andrea DALECKÁ, Wentian LU, Jaroslav HUBACEK, Hynek PIKHART and Martin BOBÁK
Publié dans: Journal of Epidemiology and Community Health, 2022, ISSN 0143-005X
Éditeur: British Medical Association
DOI: 10.1136/jech-2022-218986

Occurrence of pesticide residues in indoor dust of farmworker households across Europe and Argentina

Auteurs: NAVARRO, Irene, Adrian DE LA TORRE, Paloma SANZ, Isabelle BALDI, Paula HARKES, Esperanza HUERTA-LWANGA, Trine NORGAARD, Matjaz GLAVAN, Igor PASKOVIC, Marija Polic PASKOVIC, Nelson ABRANTES, Isabel CAMPOS, Francisco ALCON, Josefina CONTRERAS, Abdallah ALAOUI, Jakub HOFMAN, Anne VESTED, Mathilde BUREAU, Virginia APARICIO, Daniele MANDRIOLI, Daria SGARGI, Hans MOL, Violette GEISSEN, Vera SILVA and Ma
Publié dans: Science of the Total Environment, 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.167797

Predicting protein stability and solubility changes upon mutations: data perspective

Auteurs: Stanislav Mazurenko
Publié dans: ChemCatChem, Numéro 12/22, 2020, Page(s) 5590-5598, ISSN 1867-3880
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202000933

Microcystin-LR Does Not Alter Cell Survival and Intracellular Signaling in Human Bronchial Epithelial Cells

Auteurs: Ondřej Brózman, Barbara Kubickova, Pavel Babica, Petra Laboha
Publié dans: Toxins, Numéro 12/3, 2020, Page(s) 165, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins12030165

CalFitter 2.0: Leveraging the power of singular value decomposition to analyse protein thermostability

Auteurs: Antonin Kunka; David Lacko; Jan Stourac; Jiri Damborsky; Zbynek Prokop; Stanislav Mazurenko
Publié dans: Nucleic acids research, 2022, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkac378

Photochemistry of a 9‐Dithianyl‐Pyronin Derivative: A Cornucopia of Reaction Intermediates Lead to Common Photoproducts

Auteurs: Marek Martínek, Jiří Váňa, Peter Šebej, Rafael Navrátil, Tomáš Slanina, Lucie Ludvíková, Jana Roithová, Petr Klán
Publié dans: ChemPlusChem, Numéro 85/10, 2020, Page(s) 2230-2242, ISSN 2192-6506
Éditeur: Wiley-VCH Verlag
DOI: 10.1002/cplu.202000370

Trop2: Jack of All Trades, Master of None

Auteurs: Sára Lenárt, Peter Lenárt, Jan Šmarda, Ján Remšík, Karel Souček, Petr Beneš
Publié dans: Cancers, Numéro 12/11, 2020, Page(s) 3328, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12113328

IntOMICS: A Bayesian Framework for Reconstructing Regulatory Networks Using Multi-Omics Data

Auteurs: PAČÍNKOVÁ, Anna and Vlad POPOVICI
Publié dans: Journal of Computational Biology, 2023, ISSN 1066-5277
Éditeur: Mary Ann Liebert Inc.
DOI: 10.1089/cmb.2022.0149

Structures of hyperstable ancestral haloalkane dehalogenases show restricted conformational dynamics

Auteurs: Petra Babkova, Zuzana Dunajova, Radka Chaloupkova, Jiri Damborsky, David Bednar, Martin Marek
Publié dans: Computational and Structural Biotechnology Journal, Numéro 18, 2020, Page(s) 1497-1508, ISSN 2001-0370
Éditeur: Computational and Structural Biotechnology Journal
DOI: 10.1016/j.csbj.2020.06.021

Effects of all-trans and 9-cis retinoic acid on differentiating human neural stem cells in vitro

Auteurs: KUBÍČKOVÁ, Barbara, Šárka MARTINKOVÁ, Dáša BOHAČIAKOVÁ, Markéta NEZVEDOVÁ, Runze LIU, Ondřej BRÓZMAN, Zdeněk SPÁČIL and Klára HILSCHEROVÁ
Publié dans: Toxicology, 2023, ISSN 0300-483X
Éditeur: Elsevier BV
DOI: 10.1016/j.tox.2023.153461

An Explorative Analysis of ABCG2/TOP-1 mRNA Expression as a Biomarker Test for FOLFIRI Treatment in Stage III Colon Cancer Patients: Results from Retrospective Analyses of the PETACC-3 Trial

Auteurs: Jan Stenvang, Eva Budinská, Eric van Cutsem, Fred Bosman, Vlad Popovici, Nils Brünner
Publié dans: Cancers, Numéro 12/4, 2020, Page(s) 977, ISSN 2072-6694
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers12040977

Illuminating the mechanism and allosteric behavior of NanoLuc luciferase

Auteurs: Michal Nemergut, Daniel Pluskal, Jana Horackova, Tereza Sustrova, Jan Tulis, Tomas Barta, Racha Baatallah, Glwadys Gagnot, Veronika Novakova, Marika Majerova, Karolina Sedlackova, Sérgio M. Marques, Martin Toul, Jiri Damborsky, Zbynek Prokop, David Bednar, Yves L. Janin & Martin Marek
Publié dans: Nature Communications, 2023, ISSN 2041-1723
Éditeur: Nature Publishing Group
DOI: 10.1038/s41467-023-43403-y

The effects of selenium feed supplements on the oxidative stability indicators of egg yolk during the laying period

Auteurs: Fasiangova, M.; Borilova, G.; Harustiakova, D.; Kumprechtova, D.; Ciganek, M.; Hulankova, R.; Auclair, E.; Raspoet, R.
Publié dans: ACTA VETERINARIA BRNO, Numéro 00017213, 2021, ISSN 0001-7213
Éditeur: University of Veterinary and Pharmaceutical Sciences
DOI: 10.2754/avb202190040465

Providing Biological Plausibility for Exposure–Health Relationships for the Mycotoxins Deoxynivalenol (DON) and Fumonisin B1 (FB1) in Humans Using the AOP Framework

Auteurs: van den Brand, A. D., Bajard, L., Steffensen, I.-L., Brantsæter, A. L., Dirven, H. A. A. M., Louisse, J., Peijnenburg, A., Ndaw, S., Mantovani, A., De Santis, B., & Mengelers, M. J. B.
Publié dans: Toxins, Numéro 20726651, 2022, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins14040279

Fast approximative methods for study of ligand transport and rational design of improved enzymes for biotechnologies

Auteurs: VÁVRA, Ondřej, Jiří DAMBORSKÝ and David BEDNÁŘ
Publié dans: Biotechnology Advances, 2022, ISSN 0734-9750
Éditeur: Elsevier BV
DOI: 10.1016/j.biotechadv.2022.108009

The Origin of Teratogenic Retinoids in Cyanobacteria

Auteurs: Luděk Sehnal; Marie Smutná; Lucie Bláhová; Pavel Babica; Petra Šplíchalová; Klára Hilscherová
Publié dans: Toxins, 2022, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins14090636

The SAP domain of Ku facilitates its efficient loading onto DNA ends

Auteurs: FULNEČEK, Jaroslav, Eva KLIMENTOVÁ, Albert CAIRO CALZADA, Soňa BUKOVČÁKOVÁ, Panagiotis ALEXIOU, Zbyněk PROKOP and Karel ŘÍHA
Publié dans: Nucleic Acids Research, 2023, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkad850

Parental education, cognition and functional connectivity of the salience network

Auteurs: CERMAKOVA, Pavla, Adam CHLAPECKA, Zsofia CSAJBOK, Lenka ANDRÝSKOVÁ, Milan BRÁZDIL and Klára MAREČKOVÁ.
Publié dans: Nature Scientific Reports, 2023, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-023-29508-w

Treatment of cylindrospermopsin by hydroxyl and sulfate radicals: Does degradation equal detoxification?

Auteurs: Schneider, M., Grossi, M. F., Gadara, D., Spáčil, Z., Babica, P., & Bláha, L.
Publié dans: Journal of Hazardous Materials, 2022, ISSN 0304-3894
Éditeur: Elsevier BV
DOI: 10.1016/j.jhazmat.2021.127447

Current exposure to phthalates and DINCH in European children and adolescents - Results from the HBM4EU Aligned Studies 2014 to 2021

Auteurs: VOGEL, Nina, Phillipp SCHMIDT, Rosa LANGE, Antje GEROFKE, Amrit K. SAKHI, Line S. HAUG, Tina Kold JENSEN, Hanne FREDERIKSEN, Tamas SZIGETI, Zsofia CSAKO, Lubica Palkovicova MURINOVA, Miroslava SIDLOVSKA, Beata JANASIK, Wojciech WASOWICZ, Janja Snoj TRATNIK, Darja MAZEJ, Catherine GABRIEL, Spyros KARAKITSIOS, Fabio BARBONEM, Valentina ROSOLEN, Loic RAMBAUD, Margaux RIOU, Aline MURAWSKI, Daan LESEMA
Publié dans: International Journal of Hygiene and Environmental Health, 2023, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2022.114101

Spin–Vibronic Control of Intersystem Crossing in Iodine-Substituted Heptamethine Cyanines

Auteurs: Tovtik, R., Muchová, E., Štacková, L., Slavíček, P., & Klán, P.
Publié dans: The Journal of Organic Chemistry, 2023, ISSN 0022-3263
Éditeur: American Chemical Society
DOI: 10.1021/acs.joc.3c00005

Maternal Pre-Pregnancy Nutritional Status and Physical Activity Levels and a Sports Injury Reported in Children: A Seven-Year Follow-Up Study.

Auteurs: Kasović, M., Štefan, L., Piler, P., & Zvonar, M.
Publié dans: Nutrients., Numéro 20726643, 2022, ISSN 2072-6643
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/nu14040870

Performance evaluation of a diffusive hydrogel-based passive sampler for monitoring of polar organic compounds in wastewater

Auteurs: FIALOVÁ, Pavla, Roman GRABIC, Katerina GRABICOVA, Petra NOVAKOVA, Helena SVECOVA, Sarit KASERZON, Kristie THOMPSON and Branislav VRANA
Publié dans: Science of the Total Environment, 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2022.161071

Fully automated virtual screening pipeline of FDA-approved drugs using Caver Web

Auteurs: MUSIL, Miloš, Andrej JEŽÍK, Marie HAMŠÍKOVÁ, Jan ŠTOURAČ, Jakub GALGONEK, Saltuk Mustafa EYRILMEZ, Jiri VONDRASEK, Jiří DAMBORSKÝ and David BEDNÁŘ
Publié dans: Computational and Structural Biotechnology Journal, 2022, ISSN 2001-0370
Éditeur: ELSEVIER
DOI: 10.1016/j.csbj.2022.11.031

Current Advances, Research Needs and Gaps in Mycotoxins Biomonitoring under the HBM4EU—Lessons Learned and Future Trends.

Auteurs: Alvito, P., Assunção, R. M., Bajard, L., Martins, C., Mengelers, M. J. B., Mol, H., Namorado, S., van den Brand, A. D., Vasco, E., Viegas, S., & Silva, M. J.
Publié dans: Toxins, 2022, ISSN 2072-6651
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/toxins14120826

Pyrethroids and developmental neurotoxicity - A critical review of epidemiological studies and supporting mechanistic evidence.

Auteurs: Andersen, H. R., David, A., Freire, C., Fernández, M. F., D’Cruz, S. C., Reina-Pérez, I., Fini, J.-B., & Blaha, L.
Publié dans: Environmental Research, 2022, ISSN 0013-9351
Éditeur: Academic Press
DOI: 10.1016/j.envres.2022.113935

Decoding the intricate network of molecular interactions of a hyperstable engineered biocatalyst

Auteurs: Klara Markova, Klaudia Chmelova, Sérgio M. Marques, Philippe Carpentier, David Bednar, Jiri Damborsky, Martin Marek
Publié dans: Chemical Science, Numéro 11/41, 2020, Page(s) 11162-11178, ISSN 2041-6520
Éditeur: Royal Society of Chemistry
DOI: 10.1039/d0sc03367g

Biomimetic antimicrobial polymers-Design, characterization, antimicrobial, and novel applications

Auteurs: TAKAHASHI, Haruko, Iva SOVADINOVÁ, Kazuma YASUHARA, Satyavani VEMPARALA, Gregory A. CAPUTO and Kenichi KURODA
Publié dans: WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY, 2023, ISSN 1939-5116
Éditeur: WILEY
DOI: 10.1002/wnan.1866

Temporal Trends of Persistent Organic Pollutants across Africa after a Decade of MONET Passive Air Sampling

Auteurs: White, K. B.; Kalina, J.; Scheringer, M.; Pribylova, P.; Kukucka, P.; Kohoutek, J.; Prokes, R.; Klanova, J.
Publié dans: Environmental Science & Technology, Numéro 0013936X, 2021, ISSN 0013-936X
Éditeur: American Chemical Society
DOI: 10.1021/acs.est.0c03575

Cerebral organoids derived from patients with Alzheimer´s disease with PSEN1/2 mutations have defective tissue patterning and altered development

Auteurs: VÁŇOVÁ, Tereza, Jiří SEDMÍK, Jan RAŠKA, Kateřina AMRUZ ČERNÁ, Petr TAUŠ, Veronika POSPÍŠILOVÁ, Markéta NEZVEDOVÁ, Veronika FEDOROVÁ, Soňa KADÁKOVÁ, Hana KLÍMOVÁ, Michaela CAPANDOVÁ, Petra ORVISKÁ, Petr FOJTÍK, Simona BÁRTOVÁ, Karla PLEVOVÁ, Zdeněk SPÁČIL, Hana HŘÍBKOVÁ and Dáša BOHAČIAKOVÁ
Publié dans: CELL REPORTS, 2023, ISSN 2211-1247
Éditeur: Cell Press
DOI: 10.1016/j.celrep.2023.113310

Impaired lung function and mortality in Eastern Europe: results from multi-centre cohort study.

Auteurs: Sarycheva, T., Capkova, N., Pająk, A., Malyutina, S., Simonova, G., Tamosiunas, A., Bobák, M., & Pikhart, H.
Publié dans: Respiratory Research, 2022, ISSN 1465-993X
Éditeur: BMC
DOI: 10.1186/s12931-022-02057-y

Primary cilia and hypoxia-associated signaling in developmental odontogenic cysts in relation to autosomal dominant polycystic kidney disease-A novel insight

Auteurs: SZÁRAZ, Dávid, Zdeněk DANĚK, Břetislav LIPOVÝ, Jan KŘIVÁNEK, Marcela BUCHTOVÁ, Barbora Moldovan PUTNOVA, Iveta PUTNOVA, Jan ŠTEMBÍREK, Tomáš ANDRAŠINA, Petra DIVÁCKÁ, Lydie IZAKOVIČOVÁ HOLLÁ and Petra BOŘILOVÁ LINHARTOVÁ
Publié dans: Heliyon, 2023, ISSN 2405-8440
Éditeur: ELSEVIER SCI LTD
DOI: 10.1016/j.heliyon.2023.e17130

Advancing tools for human early lifecourse exposome research and translation (ATHLETE)

Auteurs: Vrijheid, Martinea–c,*; Basagaña, Xaviera–c; Gonzalez, Juan R.a–c; Jaddoe, Vincent W. V.d,e; Jensen, Genonf; Keun, Hector C.g; McEachan, Rosemary R. C.h; Porcel, Joanaa–c; Siroux, Valeriei; Swertz, Morris A.j,k; Thomsen, Cathrinel; Aasvang, Gunn Maritl; Andrušaitytė, Sandram; Angeli, Karinen; Avraam, Demetriso; Ballester, Ferranb,p,q; Burton, Paulo; Bustamante, Marionaa–c; Casas, Mari
Publié dans: Environmental Epidemiology, Numéro 24747882, 2021, ISSN 2474-7882
Éditeur: LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/ee9.0000000000000166

Neonatal Diet and Gut Microbiome Development After C-Section During the First Three Months After Birth: A Systematic Review

Auteurs: Eliska Pivrncova; Iva Kotaskova; Vojtech Thon
Publié dans: FRONTIERS IN NUTRITION, Numéro 1, 2022, ISSN 2296-861x
Éditeur: SWITZERLAND: FRONTIERS MEDIA SA
DOI: 10.3389/fnut.2022.941549

Estimation of per- and poly-fluoroalkyl substances mass loads in the Danube River using passive sampling.

Auteurs: BEGGS, Carly, Rachel MACKIE, Branislav VRANA, Roman PROKEŠ, Sara Ghorbani GORJI, Bastian SCHULZE, Kevin V.V. THOMAS, Jochen F. MUELLER and Sarit L. KASERZON.
Publié dans: Science of the Total Environment., 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.164458

Endocrine disrupting potential of replacement flame retardants-Review of current knowledge for nuclear receptors associated with reproductive outcomes

Auteurs: Lola Bajard; Chander K. Negi; Vicente Mustieles; Lisa Emily Melymuk; Stéphane Jomini; Johanna Barthelemy-Berneron; Mariana F. Fernández; Ludek Blaha
Publié dans: Environment International (2021), 153, 2021, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2021.106550

Single Cerebral Organoid Mass Spectrometry of Cell-Specific Protein and Glycosphingolipid Traits

Auteurs: Markéta Nezvedová; Durga Jha; Tereza Váňová; Darshak Gadara; Hana Klímová; Jan Raška; Lukáš Opálka; Dáša Bohačiaková; Zdeněk Spáčil
Publié dans: Analytical Chemistry, Numéro 2, 2023, ISSN 0003-2700
Éditeur: American Chemical Society
DOI: 10.1021/acs.analchem.2c00981

Titanium Dioxide Nanoparticles Modulate Systemic Immune Response and Increase Levels of Reduced Glutathione in Mice after Seven-Week Inhalation

Auteurs: MIROSLAVA, Lehotska Mikusova, Milena BUSOVA, Jana TULINSKA, Vlasta MASANOVA, Aurelia LISKOVA, Iveta UHNAKOVA, Maria DUSINSKA, Zora KRIVOSIKOVA, Eva ROLLEROVA, Radka ALACOVA, Ladislava WSOLOVA, Mira HORVATHOVA, Michaela SZABOVA, Norbert LUKAN, Zbynek VECERA, Pavel COUFALIK, Kamil KRUMAL, Lukas ALEXA, Vojtěch THON, Pavel PILER, Marcela BUCHTOVÁ, Lucie VRLÍKOVÁ, Pavel MORAVEC, Dusan GALANDA and P
Publié dans: Nanomaterials, 2023, ISSN 2079-4991
Éditeur: MDPI
DOI: 10.3390/nano13040767

Raman Microspectroscopic Analysis of Selenium Bioaccumulation by Green Alga Chlorella vulgaris.

Auteurs: Martin Kizovský; Zdeněk Pilát; Mykola Mylenko; Pavel Hrouzek; Jan Kuta; Radim Skoupý; Vladislav Krzyžánek; Kamila Hrubanova; Olga Adamczyk; Jan Ježek; Silvie Bernatová; Tereza Klementova; Alžběta Gjevik; Martin Šiler; Ota Samek; Pavel Zemánek
Publié dans: Biosensors (2021), 11(4), 115., Numéro 20796374, 2021, ISSN 2079-6374
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios11040115

Candidate genes for obstructive sleep apnea in non-syndromic children with craniofacial dysmorphisms – a narrative review

Auteurs: Zuzana Marincak Vrankova; Jan Krivanek; Zdenek Danek; Jiri Zelinka; Alena Brysova; Lydie Izakovicova Holla; James K. Hartsfield; Petra Borilova Linhartova
Publié dans: FRONTIERS IN PEDIATRICS, 2023, ISSN 2296-2360
Éditeur: SWITZERLAND: FRONTIERS MEDIA SA
DOI: 10.3389/fped.2023.1117493

SoluProtMutDB: A manually curated database of protein solubility changes upon mutations

Auteurs: VELECKÝ, Jan, Marie HAMŠÍKOVÁ, Jan ŠTOURAČ, Miloš MUSIL, Jiří DAMBORSKÝ, David BEDNÁŘ and Stanislav MAZURENKO
Publié dans: Computational and Structural Biotechnology Journal, 2022, ISSN 2001-0370
Éditeur: ELSEVIER
DOI: 10.1016/j.csbj.2022.11.009

Applicability of Scrape Loading-Dye Transfer Assay for Non-Genotoxic Carcinogen Testing

Auteurs: Sovadinova, I.; Upham, B.L.; Trosko, J.E.; Babica, P.
Publié dans: International Journal of Molecular Sciences, Numéro 14220067, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22168977

Combinatorial pathway disruption is a powerful approach to delineate metabolic impacts of endocrine disruptors.

Auteurs: BERNAL, Kevin, Charbel TOUMA, Chedi ERRADHOUANI, Talia BORONAT-BELDA, Lucas GAILLARD, Sara AL KASSIR, Helene LE MENTEC, Corinne MARTIN-CHOULY, Normand PODECHARD, Dominique LAGADIC-GOSSMANN, Sophie LANGOUET, Francois BRION, Anja KNOLL-GELLIDA, Patrick J. BABIN, Iva SOVADINOVÁ, Pavel BABICA, Karine ANDREAU, Robert BAROUKI, Jan VONDRACEK, Paloma ALONSO-MAGDALENA, Etienne BLANC, Min Ji KIM and Xavier
Publié dans: FEBS Letters, 2022, ISSN 0014-5793
Éditeur: Elsevier BV
DOI: 10.1002/1873-3468.14465

Can spirometry improve the performance of cardiovascular risk model in high-risk Eastern European countries?

Auteurs: SARYCHEVA, Tatyana Vladimirovna, Naděžda ČAPKOVÁ, Andrzej PAJAK, Abdonas TAMOSIUNAS, Martin BOBÁK and Hynek PIKHART
Publié dans: Frontiers in Cardiovascular Medicine, 2023, ISSN 2297-055X
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fcvm.2023.1228807

A large scale multi-laboratory suspect screening of pesticide metabolites in human biomonitoring: From tentative annotations to verified occurrences

Auteurs: HUBER, Carolin, Rosalie NIJSSEN, Hans MOL, Jean Philippe ANTIGNAC, Martin KRAUSS, Werner BRACK, Kevin WAGNER, Laurent DEBRAUWER, Chiara Maria VITALE, Elliott James PRICE, Jana KLÁNOVÁ, Borja Garlito MOLINA, Nuria LEON, Olga PARDO, Sandra F. FERNANDEZ, Tamas SZIGETI, Szilvia KOZEPESY, Libor ŠULC, Pavel ČUPR, Inese MARTINSONE, Lasma AKULOVA, Ilse OTTENBROS, Roel VERMEULEN, Jelle VLAANDEREN, Mirj
Publié dans: Environment International, 2022, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107452

Cumulative risk assessment of five phthalates in European children and adolescents

Auteurs: LANGE, Rosa, Nina VOGEL, Phillipp SCHMIDT, Antje GEROFKE, Mirjam LUIJTEN, Wieneke BIL, Tiina SANTONEN, Greet SCHOETERS, Liese GILLES, Amrit K SAKHI, Line S HAUG, Tina K JENSEN, Hanne FREDERIKSEN, Holger M KOCH, Tamas SZIGETI, Mate SZABADOS, Janja Snoj TRATNIK, Darja MAZEJ, Catherine GABRIEL, Dimosthenis SARIGIANNIS, Vazha DZHEDZHEIA, Spyros KARAKITSIOS, Loic RAMBAUD, Margaux RIOU, Gudrun KOPPEN, A
Publié dans: International Journal of Hygiene and Environmental Health, 2022, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2022.114052

Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling

Auteurs: MARQUES, Sérgio Manuel, Michaela SLÁNSKÁ, Klaudia CHMELOVÁ, Radka CHALOUPKOVÁ, Martin MAREK, Spencer CLARK, Jiří DAMBORSKÝ, Eric T. KOOL, David BEDNÁŘ and Zbyněk PROKOP
Publié dans: JACS AU, 2022, ISSN 2691-3704
Éditeur: AMER CHEMICAL SOC
DOI: 10.1021/jacsau.2c00002

Antiproliferative and Cytotoxic Activities of Fluorescein—A Diagnostic Angiography Dye

Auteurs: Šranková, M., Dvořák, A., Martínek, M., Šebej, P., Klán, P., Vítek, L., & Muchová, L.
Publié dans: International Journal of Molecular Sciences, Numéro 14220067, 2022, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms23031504

Patients With Common Variable Immunodeficiency (CVID) Show Higher Gut Bacterial Diversity and Levels of Low-Abundance Genes Than the Healthy Housemates.

Auteurs: Bosak, J.; Lexa, M.; Fiedorova, K.; Gadara, D.C.; Micenkova, L.; Spacil, Z.; Litzman, J.; Freiberger, T.; Smajs, D.
Publié dans: Frontiers in Immunology (2021), 12, Article Number: 671239, 2021, ISSN 1664-3224
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fimmu.2021.671239

The Role of the Oral Microbiota in the Etiopathogenesis of Oral Squamous Cell Carcinoma

Auteurs: Vyhnalova, T.; Danek, Z.; Gachova, D.; Borilova Linhartova, P.
Publié dans: Microorganisms, Numéro 20762607, 2021, ISSN 2076-2607
Éditeur: MDPI
DOI: 10.3390/microorganisms9081549

Early-Life Temperamental Differences as Longitudinal Predictors of Unintentional Injuries

Auteurs: KŠIŇAN, Albert, Andrea DALECKÁ, Lubomír KUKLA, Hynek PIKHART and Martin BOBÁK
Publié dans: Journal of Pediatric Psychology, 2024, ISSN 0146-8693
Éditeur: Oxford University Press
DOI: 10.1093/jpepsy/jsad072

Current-use pesticide exposure pathways in Czech adults and children from the CELSPAC-SPECIMEn cohort

Auteurs: ŠULC, Libor, Daniel FIGUEIREDO, Anke HUSS, Jiří KALINA, Petr GREGOR, Tomáš JANOŠ, Petr ŠENK, Andrea DALECKÁ, Lenka ANDRÝSKOVÁ, Vit KODES and Pavel ČUPR
Publié dans: Environment International, 2023, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2023.108297

Trajectories in physical functioning at older age in relation to childhood and adulthood SES and social mobility: a population-based cohort study

Auteurs: PAJAK, Andrzej, Maciej POLAK, Magdalena KOZELA, Agnieszka DORYNSKA and Martin BOBÁK
Publié dans: Frontiers in Public Health, 2023, ISSN 2296-2565
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fpubh.2023.1228920

Toxic potentials of particulate and gaseous air pollutant mixtures and the role of PAHs and their derivatives

Auteurs: Zuzana Nováková, Jiří Novák, Zoran Kitanovski, Petr Kukučka, Marie Smutná, Marco Wietzoreck, Gerhard Lammel, Klára Hilscherová
Publié dans: Environment International, Numéro 139, 2020, Page(s) 105634, ISSN 0160-4120
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2020.105634

Polymorphisms in genes expressed during amelogenesis and their association with dental caries: a case–control study

Auteurs: Daniela Gachova; Bretislav Lipovy; Tereza Deissova; Lydie Izakovicova Holla; Zdenek Danek; Petra Borilova Linhartova
Publié dans: Clinical Oral Investigations, 2023, ISSN 1432-6981
Éditeur: Springer Verlag
DOI: 10.1007/s00784-022-04794-2

An adverse outcome pathway based in vitro characterization of novel flame retardants-induced hepatic steatosis.

Auteurs: Negi, C.K.; Bajard, L.; Kohoutek, J.; Blaha, L.
Publié dans: Environmental Pollution, Numéro 02697491, 2021, ISSN 0269-7491
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.envpol.2021.117855

Different approaches to explore the impact of COVID-19 lockdowns on carbonaceous aerosols at a European rural background site

Auteurs: MBENGUE, Saliou, Petr VODIČKA, Kateřina KOMÍNKOVÁ, Naděžda ZÍKOVÁ, Jaroslav SCHWARZ, Roman PROKEŠ, Lenka SUCHÁNKOVÁ, Kajal JULAHA, Jakub ONDRÁČEK, Ivan HOLOUBEK and Vladimír ŽDÍMAL
Publié dans: Science of the Total Environment, 2023, ISSN 0048-9697
Éditeur: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.164527

Levels And Risks of Antineoplastic Drugs In Households of Oncology Patients, Hospices And Retirement Homes

Auteurs: Lucie Bláhová; Jan Kuta; Lenka Doležalová; Šárka Kozáková; Tereza Hojdarová; Luděk Bláha
Publié dans: Environmental Sciences Europe (2021), 33(1), Numéro 21904707, 2021, ISSN 2190-4707
Éditeur: Springer Verlag
DOI: 10.1186/s12302-021-00544-5

ATHLOS Healthy Aging Scale score as the predictor of all-cause mortality in Poland and Czechia

Auteurs: KOZELA, Magdalena, Andrzej PAJAK, Krystyna SZAFRANIEC, Jose Luis AYUSO-MATEOS, Martin BOBÁK, Wentian LU, Hynek PIKHART, Maciej POLAK, Albert SANCHEZ-NIUBO, Urszula STEPANIAK and Josep Maria HARO
Publié dans: Frontiers in Public Health, 2023, ISSN 2296-2565
Éditeur: FRONTIERS MEDIA SA
DOI: 10.3389/fpubh.2023.1114497

LoopGrafter: a web tool for transplanting dynamical loops for protein engineering

Auteurs: PLANAS IGLESIAS, Joan, Filip OPÁLENÝ, Pavol ULBRICH, Jan ŠTOURAČ, Zainab Kemi SANUSI, José Gaspar RANGEL PAMPLONA PIZARRO PINTO, Andrea SMITH, Jan BYŠKA, Jiří DAMBORSKÝ, Barbora KOZLÍKOVÁ and David BEDNÁŘ
Publié dans: Nucleic acids research, 2022, ISSN 0305-1048
Éditeur: Oxford University Press
DOI: 10.1093/nar/gkac249

Pathogenesis of Alzheimer´s disease: Involvement of the choroid plexus.

Auteurs: ČARNA, Maria, Isaac G. ONYANGO, Stanislav KATINA, Dušan HOLUB, Jan Sebastian NOVOTNY, Markéta NEZVEDOVÁ, Durga JHA, Zuzana NEDELSKA, Valentina LACOVICH, Thijs Vande VYVERE, Ruben HOUBRECHTS, Krystine GARCIA-MANSFIELD, Ritin SHARMA, Victoria DAVID-DIRGO, Martin VYHNALEK, Kateřina TEXLOVA, Hernan CHAVES, Nadine BAKKAR, Lucia PERTIERRA, Mojmír VINKLER, Hana MARKOVA, Jan LACZO, Kateřina SHEARDO
Publié dans: Alzheimer´s & Dementia., 2023, ISSN 1552-5260
Éditeur: Elsevier BV
DOI: 10.1002/alz.12970

Global intercomparison of polyurethane foam passive air samplers evaluating sources of variability in SVOC measurements

Auteurs: Lisa Emily Melymuk; Pernilla Bohlin Nizzetto; Tom Harner; Kevin Bradley White; Xianyu Wang; Maria Yumiko Tominaga; Jun He; Jun Li; Jianmin Ma; Wan-Li Ma; Beatriz H. Aristizábal; Annekatrin Dreyer; Begoña Jiménez; Juan Muñoz-Arnanz; Mustafa Odabasi; Yetkin Dumanoglu; Baris Yaman; Carola Graf; Andrew J. Sweetman; Jana Klánová
Publié dans: Environmental Science and Policy, Numéro 14629011, 2021, ISSN 1462-9011
Éditeur: Elsevier BV
DOI: 10.1016/j.envsci.2021.08.003

Experimental review of different plasma technologies for the degradation of cylindrospermopsin as model water pollutant

Auteurs: SCHNEIDER, Marcel, Raphael RATAJ, Luděk BLÁHA and Juergen F. KOLB
Publié dans: CHEMICAL ENGINEERING JOURNAL, 2023, ISSN 1385-8947
Éditeur: Elsevier BV
DOI: 10.1016/j.cej.2022.138984

Harmonization and Visualization of Data from a Transnational Multi-Sensor Personal Exposure Campaign

Auteurs: Rok Novak; Ioannis Petridis; David Kocman; Johanna Amalia Robinson; Tjaša Kanduč; Dimitris Chapizanis; Spyros Karakitsios; Benjamin Flückiger; Danielle Vienneau; Ondřej Mikeš; Céline Degrendele; Ondřej Sáňka; Saul García Dos Santos-Alves; Thomas Maggos; Demetra Pardali; Asimina Stamatelopoulou; Dikaia Saraga; Marco Giovanni Persico; Jaideep Visave; Alberto Gotti; Dimosthenis Sarigiannis
Publié dans: International Journal of Environmental Research and Public Health (2021), 18(21), Numéro 16604601, 2021, ISSN 1660-4601
Éditeur: MDPI
DOI: 10.3390/ijerph182111614

Seasonal variations in air concentrations of 27 organochlorine pesticides (OCPs) and 25 current-use pesticides (CUPs) across three agricultural areas of South Africa

Auteurs: Veludo, A. F., Martins Figueiredo, D., Degrendele, C., Masinyana, L., Curchod, L., Kohoutek, J., Kukučka, P., Martiník, J., Přibylová, P., Klánová, J., Dalvie, M. A., Röösli, M., & Fuhrimann, S.
Publié dans: Chemosphere, Numéro 00456535, 2022, ISSN 0045-6535
Éditeur: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2021.133162

Unraveling adipose tissue proteomic landscapes in severe obesity: insights into metabolic complications and potential biomarkers

Auteurs: Pavel Hruska; Jan Kucera; Daniela Kuruczova; Marek Buzga; Matej Pekar; Pavol Holeczy; David Potesil; Zbynek Zdrahal; Julie Bienertova-Vasku
Publié dans: AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM, 2023, ISSN 0193-1849
Éditeur: American Physiological Society
DOI: 10.1152/ajpendo.00153.2023

Proteomic Signatures of Human Visceral and Subcutaneous Adipocytes

Auteurs: Hruska, P., Kucera, J., Pekar, M., Holéczy, P., Mazur, M., Buzga, M., Kuruczova, D., Lenart, P., Fialova Kucerova, J., Potesil, D., Zdrahal, Z., & Bienertova-Vasku, J.
Publié dans: The Journal of Clinical Endocrinology & Metabolism,, Numéro 0021972X, 2022, ISSN 0021-972X
Éditeur: The Endocrine Society
DOI: 10.1210/clinem/dgab756

Multimeric structure of a subfamily III haloalkane dehalogenase-like enzyme solved by combination of cryo-EM and x-ray crystallography

Auteurs: CHMELOVÁ, Klaudia, Tadeja GAO, Martin POLÁK, Andrea SMITH, Tristan I. CROLL, Tanvir SHAIKH, Jana ŠKAŘUPOVÁ, Radka CHALOUPKOVÁ, Kay DIEDERICHS, Randy J. READ, Jiří DAMBORSKÝ, Jiří NOVÁČEK and Martin MAREK
Publié dans: Protein Science, 2023, ISSN 0961-8368
Éditeur: Cold Spring Harbor Laboratory Press
DOI: 10.1002/pro.4751

Cyanine‐Flavonol Hybrids for Near‐Infrared Light‐Activated Delivery of Carbon Monoxide

Auteurs: Lenka Štacková, Marina Russo, Lucie Muchová, Vojtěch Orel, Libor Vítek, Peter Štacko, Petr Klán
Publié dans: Chemistry – A European Journal, Numéro 26/58, 2020, Page(s) 13184-13190, ISSN 0947-6539
Éditeur: John Wiley & Sons Ltd.
DOI: 10.1002/chem.202003272

FireProt 2.0: web-based platform for the fully automated design of thermostable proteins

Auteurs: Milos Musil; Andrej Jezik; Jana Horackova; Simeon Borko; Petr Kabourek; Jiri Damborsky; David Bednar
Publié dans: BRIEFINGS IN BIOINFORMATICS, Numéro 1, 2023, ISSN 1477-4054
Éditeur: Oxford University Press
DOI: 10.1093/bib/bbad425

Tracking of anthropometric characteristics from childhood to adolescence: an 8-year follow-up findings from the Czech ELSPAC study

Auteurs: Zvonar, M., Štefan, L., Kasović, M., & Piler, P.
Publié dans: BMC Public Health, Numéro 14712458, 2022, ISSN 1471-2458
Éditeur: BioMed Central
DOI: 10.1186/s12889-022-13178-w

Structural Insights into (Tere)phthalate-Ester Hydrolysis by a Carboxylesterase and Its Role in Promoting PET Depolymerization

Auteurs: VON HAUGWITZ, Gerlis, Xu HAN, Lara PFAFF, Qian LI, Hongli WEI, Jian GAO, Karen METHLING, Yufei AO, Yannik BRACK, Jan MIČAN, Christian G FEILER, Manfred S WEISS, David BEDNÁŘ, Gottfried J. PALM, Michael LALK, Michael LAMMERS, Jiří DAMBORSKÝ, Gert WEBER, Weidong LIU, Uwe T. BORNSCHEUER and Ren WEI
Publié dans: ACS Catalysis, 2022, ISSN 2155-5435
Éditeur: American Chemical Society
DOI: 10.1021/acscatal.2c03772

Exposure to flame retardants in European children - Results from the HBM4EU aligned studies

Auteurs: VAN DER SCHYFF, Veronica, Jiří KALINA, Eva GOVARTS, Liese GILLES, Greet SCHOETERS, Argelia CASTANO, Marta ESTEBAN-LOPEZ, Jiří KOHOUTEK, Petr KUKUČKA, Adrian COVACI, Gudrun KOPPEN, Lenka ANDRÝSKOVÁ, Pavel PILER, Jana KLÁNOVÁ, Tina Kold JENSEN, Loic RAMBAUD, Margaux RIOU, Marja LAMOREE, Marike KOLOSSA-GEHRING, Nina VOGEL, Till WEBER, Thomas GOEN, Catherine GABRIEL, Dimosthenis A. SARIGIANNI
Publié dans: International Journal of Hygiene and Environmental Health, 2023, ISSN 1438-4639
Éditeur: Elsevier BV
DOI: 10.1016/j.ijheh.2022.114070

Assessing Stress in Pregnancy and Postpartum: Comparing Measures

Auteurs: Irena Štěpáníková, Elizabeth Baker, Gabriela Oates, Julie Bienertova-Vasku, Jana Klánová
Publié dans: Maternal and Child Health Journal, Numéro 24/10, 2020, Page(s) 1193-1201, ISSN 1092-7875
Éditeur: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s10995-020-02978-4

The Human Mycobiome: Colonization, Composition and the Role in Health and Disease.

Auteurs: Belvoncikova, P., Splichalova, P., Videnska, P., & Gardlik, R.
Publié dans: Journal of Fungi, 2022, ISSN 2309-608X
Éditeur: MDPI
DOI: 10.3390/jof8101046

Prevalence, awareness, treatment and control of hypertension, diabetes and hypercholesterolemia, and associated risk factors in the Czech Republic, Russia, Poland and Lithuania: a cross-sectional study.

Auteurs: Lu, W., Pikhart, H., Tamosiunas, A., Kubinova, R., Capkova, N., Malyutina, S., Pająk, A., & Bobak, M.
Publié dans: BMC Public Health, Numéro 14712458, 2022, ISSN 1471-2458
Éditeur: BioMed Central
DOI: 10.1186/s12889-022-13260-3

Domino-like effect of C112R mutation on ApoE4 aggregation and its reduction by Alzheimer’s Disease drug candidate

Auteurs: NEMERGUT, Michal, Sérgio Manuel MARQUES, Lukáš UHRÍK, Tereza VÁŇOVÁ, Markéta NEZVEDOVÁ, Darshak Chandulal GADARA, Durga JHA, Jan TULIS, Veronika NOVÁKOVÁ, Joan PLANAS IGLESIAS, Antonín KUNKA, Anthony Thomas P LEGRAND, Hana HŘÍBKOVÁ, Veronika POSPÍŠILOVÁ, Jiří SEDMÍK, Jan RAŠKA, Zbyněk PROKOP, Jiří DAMBORSKÝ, Dáša BOHAČIAKOVÁ, Zdeněk SPÁČIL, Lenka HERNYCHOVÁ, David
Publié dans: Molecular Neurodegeneration, 2023, ISSN 1750-1326
Éditeur: BioMed Central
DOI: 10.1186/s13024-023-00620-9

Flame Retardants-Mediated Interferon Signaling in the Pathogenesis of Nonalcoholic Fatty Liver Disease

Auteurs: Negi, Ch.K.; Khan, S.; Dirven, H.; Bajard, L.; Blaha, L.
Publié dans: International Journal of Molecular Sciences, Numéro 14220067, 2021, ISSN 1422-0067
Éditeur: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22084282

MicroRNAs as theranostic markers in cardiac allograft transplantation: from murine models to clinical practice

Auteurs: Novak, J.; Machackova, T.; Krejci, J.; Bienertova-Vasku, J.; Slaby, O.
Publié dans: Theranostics, Numéro 18387640, 2021, ISSN 1838-7640
Éditeur: Ivyspring International Publisher
DOI: 10.7150/thno.56327

All-cause and cardiovascular mortality in relation to lung function in the full range of distribution across four Eastern European cohorts

Auteurs: SARYCHEVA, Tatyana Vladimirovna, Nadezda CAPKOVA, Andrzej PAJAK, Sofia MALYUTINA, Abdonas TAMOSIUNAS, Martin BOBÁK and Hynek PIKHART
Publié dans: Nature Scientific Reports, 2022, ISSN 2045-2322
Éditeur: Nature Publishing Group
DOI: 10.1038/s41598-022-17261-5

Synthesis of Enantiomerically Pure Bambus[6]urils Utilizing Orthogonal Protection of Glycolurils

Auteurs: SLÁVIK, Petr, Jacopo TORRISI, Pia Yasmine JURČEK, Jan SOKOLOV and Vladimír ŠINDELÁŘ
Publié dans: Journal of Organic Chemistry, 2023, ISSN 0022-3263
Éditeur: American Chemical Society
DOI: 10.1021/acs.joc.3c00667

Mechanism-Based Strategy for Optimizing HaloTag Protein Labeling

Auteurs: Sérgio M. Marques; Michaela Slanska; Klaudia Chmelova; Radka Chaloupkova; Martin Marek; Spencer Clark; Jiri Damborsky; Eric T. Kool; David Bednar; Zbynek Prokop
Publié dans: JACS Au, 2(6), 1324–1337., Numéro 26913704, 2022, ISSN 2691-3704
Éditeur: American Chemical Society
DOI: 10.26434/chemrxiv-2021-9w10v

Anti-androgenic activity of novel flame retardants in mixtures: Newly identified contribution from tris(2,3-dibromopropyl) isocyanurate (TDBP-TAZTO)

Auteurs: Bajard, L., Vespalcová, H., Negi, C. K., Kohoutek, J., Bláha, L., & Sovadinová, I.
Publié dans: CHEMOSPHERE, 2023, ISSN 1879-1298
Éditeur: PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.chemosphere.2023.140004

Gene expression and metabolic activity of Streptococcus mutans during exposure to dietary carbohydrates glucose, sucrose, lactose, and xylitol

Auteurs: JURAKOVA, Veronika, Veronika FARKOVÁ, Jiří KUČERA, Kateřina DADÁKOVÁ, Martina ZAPLETALOVÁ, Kateřina PAŠKOVÁ, Roman ŘEMÍNEK, Zdeněk GLATZ, Lydie IZAKOVIČOVÁ HOLLÁ, Filip RŮŽIČKA, Jan LOCHMAN and Petra BOŘILOVÁ LINHARTOVÁ
Publié dans: Molecular Oral Microbiology, 2023, ISSN 2041-1006
Éditeur: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1111/omi.12428

A survey of mercury content in pig tissues carried out in the Czech Republic during years 2015-2019

Auteurs: Svoboda, M.; Bures, J.; Drapal, J.; Geboliszova, K.; Harustiakova, D.; Nepejchalova, L.; Skocovska, M.; Svobodova, Z.
Publié dans: ACTA VETERINARIA BRNO, Numéro 00017213, 2021, ISSN 0001-7213
Éditeur: University of Veterinary and Pharmaceutical Sciences
DOI: 10.2754/avb202190030287

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