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INnovative Training in Myeloid Regulatory Cell Therapy

Deliverables

Training schools proceedings: Proceedings of the three events

Proceedings of the three training schools at months 10 20 32 First submission month 10 additional due dates 20 32

Call for ESR applications

Call publication for the ESR on selected websites and through personal contacts

Recruitment of ESR

Recruitment of ESR Recruitment of the selected ESR with full employment contracts

Plan for using and disseminating knowledge

Yearly updated plan for using and disseminating knowledge First submission month 12 additional due dates 24 36 and 48

Creation of Consortium Website

Website the website public page will be developed to disseminate project results

Local Training reports

Local Training Annual reports on local training of all ESR will be submitted at months 18 30 and 42 First submission month 18 additional due dates 30 42

Reports on public engagement activities

Reports on public engagement activities submitted at months 18 30 and 42 First submission month 18 additional due dates 30 42

Training School reports

Training Schools Reports on the organisation of training Schools will be submitted at months 10 20 and 32 First submission month 10 additional due dates 20 32

Reproducible Science Policy

Reproducible Science Policy

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Publications

Regulatory Cell Therapy in Organ Transplantation: Achievements and Open Questions

Author(s): Marta Fortunato, Konstantina Morali, Laura Passeri and Silvia Gregori
Published in: Frontiers in Immunonology, 641596, 2021, ISSN 1664-3224
Publisher: Frontiers Media S.A.
DOI: 10.3389/fimmu.2021.641596

4-Octyl-Itaconate and Dimethyl Fumarate Inhibit COX2 Expression and Prostaglandin Production in Macrophages

Author(s): Ciana Diskin, Alessia Zotta, Sarah E Corcoran, Victoria J Tyrrell, Zbigniew Zaslona, Valerie B O'Donnell, Luke A J O'Neill
Published in: J. Immunol, 2021, Page(s) 2561-2569, ISSN 1550-6606
Publisher: NCBI
DOI: 10.4049/jimmunol.2100488

Regulatory Macrophages and Tolerogenic Dendritic Cells in Myeloid Regulatory Cell-Based Therapies

Author(s): Maaike Suuring and Aurélie Moreau
Published in: International journal of molecular science, 22:7970, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22157970

Transfection of Vitamin D3-Induced Tolerogenic Dendritic Cells for the Silencing of Potential Tolerogenic Genes. Identification of CSF1R-CSF1 Signaling as a Glycolytic Regulator

Author(s): María José Mansilla, Iñigo González-Larreategui, Neus Figa-Martín, Jaume Barallat, Federico Fondelli, Ares Sellés-Rius, Bibiana Quirant-Sánchez, Aina Teniente-Serra, Eva Martínez-Cáceres
Published in: International Journal of Molecular Sciences, 22:7363, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22147363

The BCG Vaccine for COVID-19: First Verdict and Future Directions

Author(s): Gonzalez-Perez M., Tarjuelo-Sanchez R., Shor Boris, Nistal-Villan E, Ochando J.
Published in: Frontiers in Immunology, 632478, 2021, ISSN 1664-3224
Publisher: Frontiers Media SA
DOI: 10.3389/fimmu.2021.632478

Differential effects of the second SARS-CoV-2 mRNA vaccine dose on T cell immunity in naive and COVID-19 recovered individuals

Author(s): Daniel Lozano-Ojalvo, Carmen Camara, Eduardo Lopez-Granados, Pilar Nozal, Lucıa del Pino-Molina, Luz Yadira Bravo-Gallego, Estela Paz-Artal, Marjorie Pion, Rafael Correa-Rocha, Alberto Ortiz, Marcos Lopez-Hoyos, Marta Erro Iribarren, Jose Portoles, Maria Pilar Rojo-Portoles, Gloria Ojeda, Isabel Cervera, Maria Gonzalez-Perez, Irene Bodega-Mayor, Maria Montes-Casado, Pilar Portoles, Mayte Perez-Ol
Published in: Cell Reports, 109570, 2021, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2021.109570

Combined Therapy of Vitamin D3-Tolerogenic Dendritic Cells and Interferon-β in a Preclinical Model of Multiple Sclerosis

Author(s): Bibiana Quirant-Sánchez,María José Mansilla, Juan Navarro-Barriuso, Silvia Presas-Rodríguez, Aina Teniente-Serra, Federico Fondelli, Cristina Ramo-Tello, Eva Martínez-Cáceres
Published in: Biomedicines, 12:1758, 2021, ISSN 2227-9059
Publisher: Multidisciplinary Digital Publishing Institute
DOI: 10.3390/biomedicines9121758

Paving the way towards an effective treatment for multiple sclerosis: advances in cell therapy

Author(s): M. J. Mansilla, S. Presas-Rodríguez, A. Teniente-Serra, I. González-Larreategui, B. Quirant-Sánchez, F. Fondelli, N. Djedovic, D. Iwaszkiewicz-Grześ, K. Chwojnicki, Đ. Miljković, P. Trzonkowski, C. Ramo-Tello & E. M. Martínez-Cáceres
Published in: Cellular & Molecular Immunology, 2021, Page(s) 1353–1374, ISSN 1672-7681
Publisher: Nature Publishing Group
DOI: 10.1038/s41423-020-00618-z

Immunogenicity and reactogenicity of BNT162b2 booster in ChAdOx1-S-primed participants (CombiVacS): a multicentre, open-label, randomised, controlled, phase 2 trial

Author(s): Alberto M Borobia, Antonio J Carcas, Mayte Pérez-Olmeda, Luis Castaño, María Jesús Bertran, Javier García-Pérez, Magdalena Campins, Antonio Portolés, María González-Pérez, María Teresa García Morales, Eunate Arana-Arri, Marta Aldea, Francisco Díez-Fuertes, Inmaculada Fuentes, Ana Ascaso, David Lora, Natale Imaz-Ayo, Lourdes E Barón-Mira, Antonia Agustí, Carla Pérez-Ingidua, Agustí
Published in: The Lancet, 2021, Page(s) 121-130, ISSN 0140-6736
Publisher: The Lancet Publishing Group
DOI: 10.1016/s0140-6736(21)01420-3

Is Citrate A Critical Signal in Immunity and Inflammation?

Author(s): lessia Zotta*, Zbigniew Zaslona, Luke A. O’Neill*
Published in: Journal of Cellular Signaling, Volume 1, Issue 3, 2020, Page(s) 87-96, ISSN 2692-0638
Publisher: Scientific Archives
DOI: 10.33696/signaling.1.017

Virus-specific memory T cell responses unmasked by immune checkpoint blockade cause hepatitis

Author(s): James A. Hutchinson, Katharina Kronenberg, Paloma Riquelme, Jürgen J. Wenzel, Gunther Glehr, Hannah-Lou Schilling, Florian Zeman, Katja Evert, Martin Schmiedel, Marion Mickler, Konstantin Drexler, Florian Bitterer, Laura Cordero, Lukas Beyer, Christian Bach, Josef Koestler, Ralph Burkhardt, Hans J. Schlitt, Dirk Hellwig, Jens M. Werner, Rainer Spang, Barbara Schmidt, Edward K. Geissler & Sebastia
Published in: Nature Communications, 1439, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-21572-y

Development of a Flow Cytometry Assay to Predict Immune Checkpoint Blockade-Related Complications

Author(s): Hannah-Lou Schilling, Gunther Glehr, Michael Kapinsky, Norbert Ahrens, Paloma Riquelme, Laura Cordero, Florian Bitterer, Hans J. Schlitt, Edward K. Geissler, Sebastian Haferkamp, James A. Hutchinson, Katharina Kronenberg
Published in: Frontiers in Immunology, 765644, 2021, ISSN 1664-3224
Publisher: Frontiers
DOI: 10.3389/fimmu.2021.765644

Complement activation induces excessive T cell cytotoxicity in severe COVID-19

Author(s): Philipp Georg, Rosario Astaburuaga-Garcıa, Lorenzo Bonaguro, Sophia Brumhard, Laura Michalick, Lena J. Lippert, Tomislav Kostevc, Christiane Gabel, Maria Schneider, Mathias Streitz, Vadim Demichev, Ioanna Gemund Matthias Barone, Pinkus Tober-Lau, Elisa T. Helbig, David Hillus, Lev Petrov, Julia Stein, Hannah-Philine Dey, Daniela Paclik, Christina Iwert, Michael Mulleder, Simran Kaur Aulakh, Sonja
Published in: Cell, 2021, Page(s) 493-512.E25, ISSN 0092-8674
Publisher: Cell Press
DOI: 10.1016/j.cell.2021.12.040