Long Acting Medicines for Complex Therapeutics Needed Now

Project Information

LongActNow

Grant agreement ID: 861278

DOI

10.3030/861278

Project closed

EC signature date 25 July 2019

Start date 1 October 2019

End date 31 March 2024

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 1 292 901,12

EU contribution

€ 1 292 901,12

Coordinated by

UNIVERSITY OF LIMERICK
Ireland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Websites, patent fillings, videos etc. (3)

LongActNow website active
New Patent applications filed
3 publications to peer reviewed journals and 3 conference presentations per ESR

Documents, reports (3)

Publication of LongActNow Open Science Strategy
Final report on use and dissemination of foreground and dissemination activities
Exploitation, dissemination and communication plan

Publications

Peer reviewed articles (14)

A comparative study of dry and wet top-down milling approaches for the preparation of microparticle suspensions

Author(s): Cañellas, F.M., Al-Rifai, N., Padrela, L., Tajber, L., Khamiakova, T., Otava, M. and Geertman, R
Published in: Powder Technology, 2023, Page(s) 118829, ISSN 0032-5910
Publisher: Elsevier BV
DOI: 10.1016/j.powtec.2023.118829

Sorbitol-coated indomethacin and naproxen particles produced by supercritical CO2-assisted spray drying

Author(s): MENDEZ CANELLAS, FIDEL; Geertman, Robert; Tajber, Lidia; Padrela, Luis
Published in: The Journal of Supercritical Fluids, Issue 199, 2023, Page(s) 105969, ISSN 0896-8446
Publisher: Elsevier BV
DOI: 10.1016/j.supflu.2023.105969

Solubility of naproxen and indomethacin in supercritical carbon dioxide/ethyl acetate mixtures.

Author(s): Kloc, A.P., Danzer, A. and Sadowski, G
Published in: Journal of Supercritical Fluids, Issue 200, 2023, Page(s) 105990, ISSN 0896-8446
Publisher: Elsevier BV
DOI: 10.1016/j.supflu.2023.105990

Membrane-Based Solvent Exchange Process for Purification of API Crystal Suspensions

Author(s): Anjum, F (Anjum, Fatima) ; Wessner, M (Wessner, Maximilian) [1] ; Sadowski, G (Sadowski, Gabriele)
Published in: Membranes, Issue 13, 3, 2023, Page(s) 263, ISSN 2077-0375
Publisher: Molecular Diversity Preservation International
DOI: 10.3390/membranes13030263

Nucleation kinetics-based solvent selection for the liquid antisolvent crystallization of a lipophilic intermediate

Author(s): Nandi, S., Padrela, L., Tajber, L. and Collas, A.,
Published in: Journal of Molecular Liquids, 2023, Page(s) 121306, ISSN 0167-7322
Publisher: Elsevier BV
DOI: 10.1016/j.molliq.2023.121306

Bottom-up production of injectable itraconazole suspensions using membrane technology

Author(s): Fatima Anjum, Thaïsa Viville, Snehashis Nandi, Maximilian Wessner, Bruno De Witte, Alain Collas, Gabriele Sadowski
Published in: International Journal of Pharmaceutics, Issue 654, 2024, Page(s) 123977, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2024.123977

Impact of Excipients and Seeding on the Solid-State Form Transformation of Indomethacin during Liquid Antisolvent Precipitation

Author(s): Mariana Hugo Silva; Ajay Kumar; Benjamin K. Hodnett; Lidia Tajber; René Holm; Sarah P. Hudson
Published in: Crystal growth & Design, Issue 2, 2022, Page(s) 6056-6069, ISSN 1528-7483
Publisher: American Chemical Society
DOI: 10.1021/acs.cgd.2c00678

Osmolality of Excipients for Parenteral Formulation Measured by Freezing Point Depression and Vapor Pressure – A Comparative Analysis

Author(s): Hugo Silva, M., Hudson, S.P., Tajber, L., Garin, M., Dong, W., Khamiakova, T. and Holm, R.
Published in: Pharmaceutical Research, Issue Volume 40, Issue 7, 2023, Page(s) 1709 - 1722, ISSN 0724-8741
Publisher: Kluwer Academic/Plenum Publishers
DOI: 10.1007/s11095-022-03262-6

Development of long-acting injectable suspensions by continuous antisolvent crystallization: An integrated bottom-up process

Author(s): Nandi, S., Padrela, L., Tajber, L. and Collas, A.
Published in: International Journal of Pharmaceutics, Issue 648, 2023, Page(s) 123550, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2023.123550

Tailoring the use of excipients in bottom-up production of naproxen crystal suspensions via membrane technology

Author(s): Anjum, F., Wessner, M., De Witte, B., Al-Rifai, N., Collas, A. and Sadowski, G.,
Published in: International Journal of Pharmaceutics, Issue 652, 2024, Page(s) 123846, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2024.123846

Continuous Microfluidic Antisolvent Crystallization as a Bottom-Up Solution for the Development of Long-Acting Injectable Formulations

Author(s): Nandi, S., Verstrepen, L., Hugo Silva, M., Padrela, L., Tajber, L. and Collas, A.
Published in: Pharmaceutics, Issue 16 (3), 2024, Page(s) 376, ISSN 1999-4923
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/pharmaceutics16030376

Supercritical enhanced atomization induced particle entrapment for continuous production of injectable micro and nano-suspensions

Author(s): Nandi, S., Collas, A., Tajber, L. and Padrela, L.
Published in: Journal of CO2 Utilization, 81,, 2024, Page(s) p.102732., ISSN 2212-9820
Publisher: Elsevier BV
DOI: 10.1016/j.jcou.2024.102732

Controlling the Polymorphism of Indomethacin with Poloxamer 407 in a Gas Antisolvent Crystallization Process

Author(s): Cañellas, F.M., Verma, V., Kujawski, J., Geertman, R., Tajber, L. and Padrela, L.
Published in: ACS omega, 2022, Page(s) 43945-43957, ISSN 2470-1343
Publisher: American Chemical Soceity
DOI: 10.1021/acsomega.2c05259

PC-SAFT-Assisted Design of Antisolvent NaproxenCrystallization in the Presence of Polymers,

Author(s): A. P. Kloc, F. Anjum, M. Wessner, S. Hudson, P. Fernandes, B. De Witte, G. Sadowski
Published in: Cryst Growth Des, Issue 24, 8, 2024, Page(s) 3419–3429, ISSN 1528-7483
Publisher: American Chemical Society
DOI: 10.1021/acs.cgd.4c00143