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Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation.

Project description

Targeted amplification of reactive oxygen species could fight serious diseases

A diet rich in antioxidants could protect against a variety of pathologies from cancer and neurological disorders to cardiovascular disease. Antioxidants soak up free radicals among which are reactive oxygen species (ROS). ROS, as their name suggests, are unstable molecules containing oxygen that easily react with other molecules in a cell. Initially considered damaging agents, we now know they also play a key role in healthy cell processes. The key seems to be in the amount of time they are present and at what levels in specific cells. NeutroCure is developing ways to control the spatial and temporal amplification of ROS generation to effectively treat severe pathological conditions characterised by a dysfunction in ROS homeostasis.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Net EU contribution
€ 629 000,00
Address
Schlossplatz 4
91054 Erlangen
Germany

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Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00

Participants (9)

UNIVERSITY OF SURREY

Participation ended

United Kingdom
Net EU contribution
€ 0,00
Address
Stag Hill
GU2 7XH Guildford

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Region
South East (England) Surrey, East and West Sussex West Surrey
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
UNIVERSITATSKLINIKUM ERLANGEN
Germany
Net EU contribution
€ 640 000,00
Address
Maximiliansplatz 2
91054 Erlangen

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Region
Bayern Mittelfranken Erlangen, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
LVIVSKYI NATIONALNYI MEDYCHNYI UNIVERSYTET IMENI DANYLA HALYTSKOHO
Ukraine
Net EU contribution
€ 400 000,00
Address
69 Pekarska Street
79010 Lviv

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Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
Spain
Net EU contribution
€ 400 000,00
Address
Calle Melchor Fernandez Almagro 3
28029 Madrid

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Region
Comunidad de Madrid Comunidad de Madrid Madrid
Activity type
Research Organisations
Non-EU contribution
€ 0,00
REDOXIS AB
Sweden
Net EU contribution
€ 400 000,00
Address
Medicon Village Scheelevagen 2
223 81 Lund

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Södra Sverige Sydsverige Skåne län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

PRONOXIS AB
Sweden
Net EU contribution
€ 0,00
Address
Skogvaktaregatan 8
461 33 Trollhattan

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Södra Sverige Västsverige Västra Götalands län
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Non-EU contribution
€ 0,00
INSTITUT GUSTAVE ROUSSY
France
Net EU contribution
€ 120 000,00
Address
Rue Camille Desmoulins 39
94805 Villejuif

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Region
Ile-de-France Ile-de-France Val-de-Marne
Activity type
Research Organisations
Non-EU contribution
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE
France
Net EU contribution
€ 0,00
Address
Rue De Tolbiac 101
75654 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Non-EU contribution
€ 0,00
SWANSEA UNIVERSITY
United Kingdom
Net EU contribution
€ 410 998,75
Address
Singleton Park
SA2 8PP Swansea

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Region
Wales West Wales and The Valleys Swansea
Activity type
Higher or Secondary Education Establishments
Non-EU contribution
€ 0,00