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Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation.

Projektbeschreibung

Targeted amplification of reactive oxygen species could fight serious diseases

A diet rich in antioxidants could protect against a variety of pathologies from cancer and neurological disorders to cardiovascular disease. Antioxidants soak up free radicals among which are reactive oxygen species (ROS). ROS, as their name suggests, are unstable molecules containing oxygen that easily react with other molecules in a cell. Initially considered damaging agents, we now know they also play a key role in healthy cell processes. The key seems to be in the amount of time they are present and at what levels in specific cells. NeutroCure is developing ways to control the spatial and temporal amplification of ROS generation to effectively treat severe pathological conditions characterised by a dysfunction in ROS homeostasis.

Wissenschaftliches Gebiet

Aufforderung zur Vorschlagseinreichung

H2020-FETOPEN-2018-2019-2020-01
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

RIA - Research and Innovation action

Koordinator

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG
Adresse
Schlossplatz 4
91054 Erlangen
Deutschland
Aktivitätstyp
Higher or Secondary Education Establishments
EU-Beitrag
€ 629 000

Beteiligte (6)

UNIVERSITY OF SURREY
United Kingdom
EU-Beitrag
€ 410 998,75
Adresse
Stag Hill
GU2 7XH Guildford
Aktivitätstyp
Higher or Secondary Education Establishments
UNIVERSITATSKLINIKUM ERLANGEN
Deutschland
EU-Beitrag
€ 640 000
Adresse
Maximiliansplatz 2
91054 Erlangen
Aktivitätstyp
Higher or Secondary Education Establishments
LVIVSKYI NATIONALNYI MEDYCHNYI UNIVERSYTET IMENI DANYLA HALYTSKOHO
Ukraine
EU-Beitrag
€ 400 000
Adresse
69 Pekarska Street
79010 Lviv
Aktivitätstyp
Higher or Secondary Education Establishments
CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)
Spanien
EU-Beitrag
€ 400 000
Adresse
Calle Melchor Fernandez Almagro 3
28029 Madrid
Aktivitätstyp
Research Organisations
REDOXIS AB
Schweden
EU-Beitrag
€ 400 000
Adresse
Medicon Village Scheelevagen 2
223 81 Lund
Aktivitätstyp
Private for-profit entities (excluding Higher or Secondary Education Establishments)
INSTITUT GUSTAVE ROUSSY
Frankreich
EU-Beitrag
€ 120 000
Adresse
Rue Camille Desmoulins 39
94805 Villejuif
Aktivitätstyp
Research Organisations