Development of “smart” amplifiers of reactive oxygen species specific to aberrant polymorphonuclear neutrophils for treatment of inflammatory and autoimmune diseases, cancer and myeloablation.

Projektbeschreibung

Targeted amplification of reactive oxygen species could fight serious diseases

A diet rich in antioxidants could protect against a variety of pathologies from cancer and neurological disorders to cardiovascular disease. Antioxidants soak up free radicals among which are reactive oxygen species (ROS). ROS, as their name suggests, are unstable molecules containing oxygen that easily react with other molecules in a cell. Initially considered damaging agents, we now know they also play a key role in healthy cell processes. The key seems to be in the amount of time they are present and at what levels in specific cells. NeutroCure is developing ways to control the spatial and temporal amplification of ROS generation to effectively treat severe pathological conditions characterised by a dysfunction in ROS homeostasis.

Wissenschaftliches Gebiet

Programm/Programme

• H2020-EU.1.2.1. - FET Open

Thema/Themen

• FETOPEN-01-2018-2019-2020 - FET-Open Challenging Current Thinking

Aufforderung zur Vorschlagseinreichung

H2020-FETOPEN-2018-2019-2020-01
Andere Projekte für diesen Aufruf anzeigen

Finanzierungsplan

RIA - Research and Innovation action

Koordinator

FRIEDRICH-ALEXANDER-UNIVERSITAET ERLANGEN-NUERNBERG

Adresse

Schlossplatz 4
91054 Erlangen
Deutschland

Aktivitätstyp

Higher or Secondary Education Establishments

EU-Beitrag

€ 629 000

Beteiligte (6)

UNIVERSITY OF SURREY

United Kingdom

EU-Beitrag

€ 410 998,75

Adresse

Stag Hill
GU2 7XH Guildford

Aktivitätstyp

Higher or Secondary Education Establishments

UNIVERSITATSKLINIKUM ERLANGEN

Deutschland

EU-Beitrag

€ 640 000

Adresse

Maximiliansplatz 2
91054 Erlangen

Aktivitätstyp

Higher or Secondary Education Establishments

LVIVSKYI NATIONALNYI MEDYCHNYI UNIVERSYTET IMENI DANYLA HALYTSKOHO

Ukraine

EU-Beitrag

€ 400 000

Adresse

69 Pekarska Street
79010 Lviv

Aktivitätstyp

Higher or Secondary Education Establishments

CENTRO NACIONAL DE INVESTIGACIONES CARDIOVASCULARES CARLOS III (F.S.P.)

Spanien

EU-Beitrag

€ 400 000

Adresse

Calle Melchor Fernandez Almagro 3
28029 Madrid

Aktivitätstyp

Research Organisations

REDOXIS AB

Schweden

EU-Beitrag

€ 400 000

Adresse

Medicon Village Scheelevagen 2
223 81 Lund

Aktivitätstyp

Private for-profit entities (excluding Higher or Secondary Education Establishments)

INSTITUT GUSTAVE ROUSSY

Frankreich

EU-Beitrag

€ 120 000

Adresse

Rue Camille Desmoulins 39
94805 Villejuif

Aktivitätstyp

Research Organisations