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MAssive intracellular REcording for Pharmacology

Project description

Measuring action potentials in thousands of cells at once streamlines cardiac safety testing

High-throughput screening has revolutionised drug discovery and toxicity testing. However, determining the cardiac safety of potential drugs still remains a time-intensive and costly endeavour beginning with tests on cell lines, followed by computational simulations and lastly human trials. The EU-funded MAREP project plans to deliver a fast, automated and affordable alternative. Scientists have developed a platform that enables simultaneous recording of action potentials from thousands of cardiac cells in culture in response to drug application. It could significantly streamline the drug development process and enhance patient safety.

Call for proposal

ERC-2019-PoC
See other projects for this call

Funding Scheme

ERC-POC-LS - ERC Proof of Concept Lump Sum Pilot

Host institution

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Address
Via Morego 30
16163 Genova
Italy
Activity type
Research Organisations
EU contribution
€ 150 000

Beneficiaries (1)

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy
EU contribution
€ 150 000
Address
Via Morego 30
16163 Genova
Activity type
Research Organisations