Next generation test bed for upscaling of microfluidic devices based on nano-enabled surfaces and membranes

Project Information

NextGenMicrofluidics

Grant agreement ID: 862092

DOI

10.3030/862092

Project closed

EC signature date 12 March 2020

Start date 1 April 2020

End date 31 March 2025

Funded under

• INDUSTRIAL LEADERSHIP - Leadership in enabling and industrial technologies - Advanced materials

Total cost

€ 17 346 893,23

EU contribution

€ 14 692 025,51

Coordinated by

JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH
Austria

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Documents, reports (2)

D4.5 Catalogue of development services for customers that the value chain offers

The catalogue describes all products and services incl related costs supply times design rules or other for the quoting relevant restrictions that the MIH will be supplying to the market after the implementation of the project

D9.1 Open Call Document

This document will be published to inform possible customers about the services and products offered by the MIH It contains all relevant information for a company to register their interest in development services from the consortium The document also includes evaluation criteria

Other (1)

D2.1 Public project website online

The document related to this deliverable will provide an overview of the work done domain reservation webhosting image search and licencing screen design process etc and give an overview of the website including screenshots

Publications

Conference proceedings (12)

IN-LINE QUALITY CONTROL SYSTEM FOR THE STATE-OF-THE-ART ROLL-TO-ROLL MASS-MANUFACTURING PROCESS FOR VERSATILE MICROFLUIDIC SYSTEMS

Author(s): Okulova, N.; V. J. Tolstrup 1, V.J.; O ´ Sullivan 1, C.; Haase, A.; Smolka, M.; Rodriguez, A.; Flanschger, A.; Conde, A.; Skolimowski, M.; Mora Sanz, V.; Briz, N.; Kafka, J.
Published in: Issue 1, 2024
Publisher: Microtas
DOI: 10.5281/zenodo.15275507

MANUFACTURING OF FOIL-BASED MICROFLUIDIC CHIPS FOR NEURON CELL CULTURE AND AXON OUTGROWTH MONITORING

Author(s): Atak, Nihan
Published in: Issue 1, 2023
Publisher: SelectBIO
DOI: 10.5281/zenodo.15198145

Development of Neuronal Junction Chamber with High-Precision Roll-to-Roll (R2R) Manufacturing

Author(s): Atak, Nihan
Published in: Issue 1, 2024
Publisher: Microtas
DOI: 10.5281/zenodo.15197817

Point-of-Need Lab-on-a-Chip for Industrial Enzyme Detection

Author(s): Mora-Sanz, Dr Verónica
Published in: Issue 5, 2025
Publisher: NGM Final Dissemination Event
DOI: 10.5281/zenodo.15210234

Large-Scale Manufacturing of Foil-Based Microfluidic Chips for Neuron Cell Culture and Axon Outgrowth Monitoring. μTAS 2023

Author(s): Atak, Nihan
Published in: Issue 1, 2023
Publisher: Microtas
DOI: 10.5281/zenodo.15198318

Development of neuronal junction chamber via high-precision Roll-to-Roll (R2R) manufacturing

Author(s): Atak, Nihan
Published in: Issue 1, 2024
Publisher: EUROoCs
DOI: 10.5281/zenodo.15197886

LATE-PCR for LoC Molecular Diagnostics Devices and Its Application to the Sensitive Detection of SARS-CoV-2

Author(s): Dimitrios Karadimas, George Tsekenis
Published in: Proceedings of The 8th International Symposium on Sensor Science, 2021, ISSN 2673-4591
Publisher: MDPI
DOI: 10.3390/i3s2021dresden-10076

Large-Scale Manufacturing of Foil-Based Microfluidic Chips

Author(s): Atak, Nihan
Published in: Issue 3, 2024
Publisher: TechForum Millstatt
DOI: 10.5281/zenodo.15198052

DEVELOPMENT OF NEURONAL JUNCTION CHAMBER VIA HIGH-PRECISION ROLL-TO-ROLL (R2R) MANUFACTURING

Author(s): Nihan Atak
Published in: 2024 MicroTAS Book of Abstracts, 2025
Publisher: Chemical and Biological Microsystems Society
DOI: 10.70477/qzff6707

Enzyme Activity Monitoring In Industrial Solid-State Fermentation Processes Based On Colorimetric Loc Compatible with R2R Fabrication

Author(s): Verónica Mora-Sanz, Elisabeth Hengge, Álvaro Conde, Maciej Skolimowski, Conor O’Sullivan, Nastasia Okulova, Andoni Rodriguez, Caroline Hennigs, Matija Strbac, Bernd Nidetzky, Goran Bijelic, Nerea Briz
Published in: World Congress on Electrical Engineering and Computer Systems and Science, Proceedings of the 10th World Congress on Electrical Engineering and Computer Systems and Science, 2024
Publisher: Avestia Publishing
DOI: 10.11159/icbes24.160

We get microfluidics Rolling. Advantages of Roll-to-roll Replication.

Author(s): Kafka, Jan; Conde, Alvaro; Haase, Anja; Brommert, Janine; Lohse, Mirko
Published in: Issue 1, 2022
Publisher: Microfluidics Innovation Hub
DOI: 10.5281/zenodo.15260406

Imprinting of residual-layer-thickness optimized large micro-structures enabled by the new organic photo-curable NIL resist «mr-NIL210SF»

Author(s): Lohse, Mirko
Published in: Issue 2, 2024
Publisher: International Micro and Nano Engineering Conference (MNE)
DOI: 10.5281/zenodo.15274601

Peer reviewed articles (6)

Roll-to-Roll (R2R) High-Throughput Manufacturing of Foil-Based Microfluidic Chips for Neurite Outgrowth Studies

Author(s): Nihan Atak, Martin Smolka, Anja Haase, Alexandra Lorenz, Silvia Schobesberger, Stephan Ruttloff, Christian Wolf, Ana Ayerdi-Izquierdo, Peter Ertl, Nerea Briz Iceta, Jan Hesse, Martin Frauenlob
Published in: Micromachines, Issue 16, 2025, Page(s) 713, ISSN 2072-666X
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/mi16060713

Translation of COVID-19 Serology Test on Foil-Based Lateral Flow Chips: A Journey from Injection Molding to Scalable Roll-to-Roll Nanoimprint Lithography

Author(s): Pakapreud Khumwan, Stephan Ruttloff, Johannes Götz, Dieter Nees, Conor O’Sullivan, Alvaro Conde, Mirko Lohse, Christian Wolf, Nastasia Okulova, Janine Brommert, Richard Benauer, Ingo Katzmayr, Nikolaus Ladenhauf, Wilfried Weigel, Maciej Skolimowski, Max Sonnleitner, Martin Smolka, Anja Haase, Barbara Stadlober, Jan Hesse
Published in: Biosensors, Issue 15, 2025, Page(s) 229, ISSN 2079-6374
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/bios15040229

Novel Concept of Micro Patterned Micro Titer Plates Fabricated via UV-NIL for Automated Neuronal Cell Assay Read-Out

Author(s): Mirko Lohse, Manuel W. Thesen, Anja Haase, Martin Smolka, Nerea Briz Iceta, Ana Ayerdi Izquierdo, Isbaal Ramos, Clarisa Salado, Arne Schleunitz
Published in: Nanomaterials, Issue 11/4, 2021, Page(s) 902, ISSN 2079-4991
Publisher: Konstantins Jefimovs
DOI: 10.3390/nano11040902

Lab-on-a-foil devices with integrated retro-reflective structures for multiplexed DNA testing

Author(s): Pelin Toren, Andreas Proksch, Martin Smolka, Anja Haase, Dieter Nees, Stephan Ruttloff, Johannes Goetz, Christian Wolf, Bettina Hierschlager, Ingo Katzmayr, Max Sonnleitner, Barbara Stadlober, Jan Hesse
Published in: MRS Advances, 2021, ISSN 2059-8521
Publisher: Springer Nature Switzerland AG. Part of Springer Nature.
DOI: 10.1557/s43580-021-00064-7

High-throughput roll-to-roll production of polymer biochips for multiplexed DNA detection in point-of-care diagnostics

Author(s): Pelin Toren, Martin Smolka, Anja Haase, Ursula Palfinger, Dieter Nees, Stephan Ruttloff, Ladislav Kuna, Cindy Schaude, Sandra Jauk, Markus Rumpler, Bettina Hierschlager, Ingo Katzmayr, Max Sonnleitner, Manuel W. Thesen, Mirko Lohse, Martin Horn, Wilfried Weigel, Matija Strbac, Goran Bijelic, Suhith Hemanth, Nastasia Okulova, Jan Kafka, Stefan Kostler, Barbara Stadlober, Jan Hesse
Published in: Lab on a Chip, 2020, ISSN 1473-0197
Publisher: Royal Society of Chemistry
DOI: 10.1039/d0lc00751j

2025 photonics for agrifood roadmap: towards a sustainable and healthier planet

Author(s): Lien Smeesters, Francesca Venturini, Stefan Paulus, Anne-Katrin Mahlein, David Perpetuini, Daniela Cardone, Arcangelo Merla, Benjamin Gac, Stephane Perrin, Denis Trégoat, Luiz Poffo, Antoine Fournier, Giuseppe Bonifazi, Silvia Serranti, Wenzhi Liao, Noureddin Osseiran, Mathias Vanwolleghem, Romain Peretti, Aparajita Bandyopadhyay, Karl Bertling, Krishnan Parameswaran, Aleksandar D. Rakić, Amarty
Published in: Journal of Physics: Photonics, 2025, Page(s) 146-152, ISSN 2515-7647
Publisher: Purpose-led Publishing, IOP Publishing Ltd
DOI: 10.1088/2515-7647/adbea9

Other (3)

Next Generation of Microfluidics for safe and sustainable diagnostics devices

Author(s): Wolf, Clemens; Argarate, Nerea; Resch, Susanne; Scheper, Johanna; Falk, Andreas
Published in: Issue 1, 2022
Publisher: NanoCommons Final Conference
DOI: 10.5281/zenodo.6876149

Microfluidic chip for in vitro neuronal cell culture under electrical stimulation

Author(s): Ana, A., atak, . nihan ., Roura, M., Tomasova, L., conde, . alvaro ., O'Sullivan, C., & Lohse, M.
Published in: 2024
Publisher: 11th International Conference on Biomedical Engineering and Systems (ICBES 2024)
DOI: 10.5281/zenodo.13833247

Microfluidic in vitro systems for neurological disease modeling under electrical stimulation

Author(s): Meritxell Roura Ferrer, Clarisa Salado, Ana Ayerdi-Izquierdo, Nihan Atak, Anja Haase, Martin Smolka, Jan Kafka, Lea Tomasova, Alvaro Conde, Maciej Skolimowski, Conor O'Sullivan, Nastasia Okulova, & Mirko Lohse.
Published in: 2024
Publisher: SLAS2024 International Conference and Exhibition
DOI: 10.5281/zenodo.10926928

Intellectual Property Rights

Patent (8)

METHOD FOR FORMING A BOND BETWEEN TWO SUBSTRATES OF A DEVICE; DEVICE OBTAINABLE BY THE METHOD; A MICROFLUIDIC DEVICE; AND USE OF THE DEVICE

Application/Publication number: 20 22057333
Date: 2022-03-21
Applicant(s): MICRONIT BV

MICROFLUIDIC SYSTEM CONSISTING OF A FOLDED FOIL, AND PRODUCTION METHOD

Application/Publication number: 20 22053879
Date: 2022-02-17
Applicant(s): JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH

COMPONENT WITH MICROFLUIDIC STRUCTURES, METHOD FOR THE PRODUCTION AND USE THEREOF

Application/Publication number: 20 22053879
Date: 2021-04-13
Applicant(s): JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH

MICROFLUIDIC DEVICES AND METHODS

Application/Publication number: 21 382293
Date: 2021-04-07
Applicant(s): FUNDACION TECNALIA RESEARCH & INNOVATION

CELLULOSE AND NANOCELLULOSE BASED BIOINKS

Application/Publication number: 22 383326
Date: 2022-12-30
Applicant(s): FUNDACION TECNALIA RESEARCH & INNOVATION

SAMPLE CARRIER

Application/Publication number: 22 169988
Date: 2022-04-26
Applicant(s): IBIDI GMBH

COMPONENT WITH MICROFLUIDIC STRUCTURES, METHOD FOR THE PRODUCTION AND USE THEREOF

Application/Publication number: 21 719557
Date: 2021-04-13
Applicant(s): JOANNEUM RESEARCH FORSCHUNGSGESELLSCHAFT MBH

MICROFLUIDIC CHIP

Application/Publication number: 20 22058444
Date: 2022-03-30
Applicant(s): GENSPEED BIOTECH GMBH