Deliverables
Report containing release rates and forms data, obtained by measuring NM release from NEPs life-cycle stages, through the access to ASINA testbeds facilities or laboratory-controlled simulations and corresponding p-chem characterization of released materials.
Nano-Risk assessment and recommendations for product safety requirementsReport including the safety profiles of the proposed design strategies, by using higher tier risk assessment models. The report will also include two sections reporting compliance of ASINA design solutions with the two VCs frameworks (REACH, biocides and cosmetics): suggesting design criteria and evaluating the proposed design solutions, in response to regulatory obligations.
Data Curation and DB establishmentA comprehensive ASINA project database system containing ASINA properties and performances attributes generated by WP1, 2, 3 as well as data collected from sources external to the project (databases, literature data, data obtained by interaction with other projects). The deliverable will also report the standardised ontology and templates used to describe all experiments and data generated within the project.
Roadmap outlining ASINA-SMM outputsDescription of the outputs delivered by ASINA-SMM, organised in three main sections: Strategy (SbD solutions, rational behind, methods for testing and ranking them), Implementation (guidelines for their implementation at pilot scale, results of validation tests, suggestion for their transferability to other applications and industrial sectors), Execution (regulatory and standardisation issues for delivering SBD solutions in compliance with existing rules and in a shape of a future standard).
Preliminary risk assessment of SbD solutions for the production of target NEPsReport about the results of a preliminary characterization of risk applying low tier risk assessments models of the identified design alternatives to assist WP1 and WP3 on the selection of the optimum SbD strategies
Regulatory and standardization issues involvedProposal of guidelines for the practical execution of ASINA SdB solutions, in compliance with existing rules (REACH, Biocides, Cosmetics, Medical Devices), in a shape of a future, new standards and/or inputs to existing standards, specifically conceived for promoting SbD nanomanufacturing.
Prediction of NM fate and exposure levels in humans and environmentReport outlining the relationships between key driving NM properties and extrinsic parameters and exposure performances (fate and exposure levels) in humans and environment.
Specifications for the use of existing resources in ASINA processesReport suggesting technical specifications for the adequate use of PSbD resources identified in D31 describing in each case the necessary adaptations to ensure friendliness easy use and practical implementation of such solutions
NM p-chem properties database with respect to their intended use and NEPReport including the OECD suggested worksheets for the definition of NM identity, intended use and behavior. The deliverable will also report a set of identified p-chem parameters (and methods for their measurement) that may affect technical performances related to material and product functionality (characterizing factors), with the identification, when possible, of modifying properties and variability ranges.
Characterization factors and attributes related to NM and NEPs functionalityReport containing technical performance attributes (and methods for their measurement) related to functionality of NM and NEPs. The performances attributes of materials and products of the two VCs will encompass the antimicrobial activity of raw materials and coated surfaces, the encapsulating efficiency and delivery capacity of nano-capsules, as well as further technical performances referred to coating or nano-encapsulating systems stability, durability, transformation.
NM collection, distribution and M-SbD hypothesisSelection of target NM and NEPs and hypothesis of MSbD solutions 1 candidate antimicrobial NM or encapulating agentadditives and their possible modification 2 analysis of processability in the existing pilots 3 method of delivery how will the NM act how will the resulting NEP be used 4 potential alternativesmodifications for decreasing hazard or exposure potential
Map of existing resources for P-SbDReport on the identification description and priorization of existing PSbD strategies and resources including gaps identification
ASINA ML Tool Train, Test and ValidationReport on the results of validation tests and the identification of response functions linking all materials and process parameters to the properties of concerns.
Characterization of the p-chem properties affecting toxicity and AOPsReport outlining the relationships between AOPs linking pchem properties and hazard potential showing molecular initiating events key events and key event relationships proposing easy and rapid assays to identify key events and describing the adverse outcome
Project logo website brochure poster
Training PlanPublications
Author(s):
Irini Furxhi; Antti Joonas Koivisto; Finbarr Murphy; Sara Trabucco; Benedetta Del Secco; Athanasios Arvanitis
Published in:
Volume 11, Issue 2, 2021, Page(s) 22, ISSN 2079-4991
Publisher:
Nanomaterials
DOI:
10.3390/nano11071818
Author(s):
Ozge Kose, Paride Mantecca, Anna Costa, Marie Carrière
Published in:
Particle and Fibre Toxicology, Issue 20(1), 2022, ISSN 1743-8977
Publisher:
BioMed Central
DOI:
10.21203/rs.3.rs-2173816/v1
Author(s):
Laura Faccani, Simona Ortelli, Magda Blosi, Anna Costa
Published in:
Catalysts, Issue 021, 11(11), 141, 2021, ISSN 2073-4344
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/catal11111418
Author(s):
Furxhi Irini
Published in:
NanoImpact, Issue Volume 25, January 2022, 100378, 2022, Page(s) 1818, ISSN 2452-0748
Publisher:
ELSEVIER
DOI:
10.1016/j.impact.2021.100378
Author(s):
Irini Furxhi, Rossella Bengalli, Giulia Motta, Paride Mantecca, Ozge Kose, Marie Carriere, Ehtsham Ul Haq, Charlie O'Mahony, Magda Blosi, Davide Gardini and Anna Costa
Published in:
ACS Appl. Nano Mater. 2023, 2023, ISSN 2574-0970
Publisher:
ACS Publications
DOI:
10.1021/acsanm.3c00173
Author(s):
Mahsa Mirzaei, Irini Furxhi, Finbarr Murphy, Martin Mullins
Published in:
International Journal of Molecular Sciences, 2023, ISSN 1422-0067
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms24032792
Author(s):
Irini Furxhi, Anna Costa, Socorro Vazquez Campos, Carlos Fito-Lopez, Danail Hristozov, Juan Antonio Tamayo Ramos, Susanne Resch, Margherita Cioffi, Steffi Friedrichs, Cris Rocca, Eugenia Valsami-Jones, Iseult Lynch, Sanchez Jimenez Aracel, Lucian Farcal
Published in:
RSC Sustainability, 2023, ISSN 1757-7047
Publisher:
Royal Society of Chemistry
DOI:
10.1039/d2su00101b
Author(s):
Jesús M. López de Ipiña, Gabriel Aznar, Alberto Lopez, Jorge Olite, Joonas Koivisto, Gianni Bartolini, Anna Costa
Published in:
Journal of Physics Conference Series, Issue (1953):012010, 2021, Page(s) 12010, ISSN 1742-6596
Publisher:
IOP Science
DOI:
10.1088/1742-6596/1953/1/012010
Author(s):
Anna Luisa Costa, Magda Blosi, Andrea Brigliadori, Ilaria Zanoni, Simona Ortelli, Felice Carlo Simeone, Serena Delbue, Sarah D'Alessandro, Silvia Parapini, Claudia Vineis, Alessio Varesano, Muhammet S. Toprak, Bejan Hamawandif, Davide Gardini
Published in:
Environmental Science: Nano, Issue 2022, 9, 4295-4304, 2022, ISSN 2051-8161
Publisher:
Royal Society of Chemistry
DOI:
10.1039/d2en00178k
Author(s):
Franco Belosi , Antti Joonas Koivisto, Irini Furxhi, Jesús Lopez de Ipiña , Alessia Nicosia, Fabrizio Ravegnani, Simona Ortelli, Ilaria Zanoni, Anna Costa
Published in:
NanoImpact, Issue 30(2023) 100459, 2023, ISSN 2452-0748
Publisher:
Elsevier
DOI:
10.1016/j.impact.2023.100459
Author(s):
Antti Joonas Koivisto; Benedetta Del Secco; Sara Trabucco; Alessia Nicosia; Fabrizio Ravegnani; Marko Altin; Joan Cabellos; Irini Furxhi; Magda Blosi; Anna Costa; Jesús Lopez de Ipiña; Franco Belosi
Published in:
Nanomaterials; Volume 12; Issue 4; Pages: 596, Issue 4, 2022, Page(s) 23, ISSN 2079-4991
Publisher:
Nanomaterials
DOI:
10.3390/nano12040596
Author(s):
Antti Joonas Koivisto, Marko Altin, Irini Furxhi, Maxime Eliat, Sara Trabucco, Magda Blosi, Jesús Lopez de Ipiña, Franco Belosi, Anna Costa
Published in:
Nanomaterials, Issue 2022, 12, 4089, 2022, Page(s) 4089, ISSN 2079-4991
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/nano12224089
Author(s):
Giulia Motta, Maurizio Gualtieri, Rossella Bengalli, Melissa Saibene, Franco Belosi, Alessia Nicosia, Joan Cabellos, Paride Mantecca
Published in:
Environmental International, Issue Volume 183, January 2024, 108420, 2024, ISSN 1873-6750
Publisher:
Elsevier
DOI:
10.1016/j.envint.2024.108420
Author(s):
Mahsa Mirzaei, Irini Furxhi, Finbarr Murphy, Martin Mullins
Published in:
Nanomaterials, Issue 2021, 11(12), 1532, 2021, ISSN 2079-4991
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/coatings11121532
Author(s):
Irini Furxhi, Alessio Varesano, Hesham Salman,Mahsa Mirzaei,Vittoria Battistello,Ivonne Tonani Tomasoni and Magda Blosi
Published in:
Coatings (Special Issue Biomaterials and Antimicrobial Coatings), Issue 2021, 11(12), 1486, 2021, ISSN 2079-6412
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/coatings11121486
Author(s):
Mahsa Mirzaei, Irini Furxhi, Finbarr Murphy, Martin Mullins
Published in:
Nanomaterials, Issue 11/7, 2021, Page(s) 1774, ISSN 2079-4991
Publisher:
Nanomaterials
DOI:
10.3390/nano11071774
Author(s):
Benedetta Del Secco, Sara Trabucci, Fabrizio Ravegnani, Antii Joonas Koivisto, Magda Blosi, Ilaria Zanoni, Simona Ortelli, Marko Altin, Gianni Bartolini, Anna Costa, Franco Belosi
Published in:
Nanomaterials, Issue 2022, 12, 313, 2022, Page(s) 313, ISSN 2079-4991
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/nano12030313
Author(s):
Antti Joonas Koivisto; Sara Trabucco; Fabrizio Ravegnani; Francescopiero Calzolari; Alessia Nicosia; Benedetta Del Secco; Marko Altin; Elisa Morabito; Magda Blosi; Anna Costa; Franco Belosi
Published in:
Open Research Europe, Issue 7, 2022, ISSN 2732-5121
Publisher:
Open Research Europe
DOI:
10.12688/openreseurope.14771.1
Author(s):
Kose, O.; Béal, D.; Motellier, S.; Pelissier, N.; Collin-Faure, V.; Blosi, M.; Bengalli, R.; Costa, A.; Furxhi, I.; Mantecca, P.; Carriere, M.
Published in:
Toxics, Issue 2023, 11(3), 199, 2023, ISSN 2305-6304
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/toxics11030199
Author(s):
Sara Trabucco, Antti Joonas Koivisto, Fabrizio Ravegnani, Simona Ortelli, Ilaria Zanoni,
Magda Blosi, Anna Luisa Costa, Franco Belosi
Published in:
Toxics, Issue 2022,10, 498, 2022, Page(s) 498, ISSN 2305-6304
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/toxics10090498
Author(s):
Giulia Motta, Maurizio Gualtieri,Melissa Saibene, Rossella Bengalli, Andrea Brigliadori, Marie Carrière, Paride Mantecca
Published in:
Toxics, Issue 2023, 11(2), 195, 2023, ISSN 2305-6304
Publisher:
Toxics
DOI:
10.3390/toxics11020195
Author(s):
Irini Furxhi, Athanasios Arvanitis, Finbarr Murphy, Anna Costa, Magda Blosi
Published in:
Nanomaterials, Issue 11/6, 2021, Page(s) 1520, ISSN 2079-4991
Publisher:
Nanomaterials
DOI:
10.3390/nano11061520
Author(s):
Irini Furxhi, Egon WiIlighagen, Chris Evelo, Anna Costa, Ammar Ammar
Published in:
NanoImpact, 2023, ISSN 2452-0748
Publisher:
Elsevier
DOI:
10.1016/j.impact.2023.100475
Author(s):
Sara Trabucco, Simona Ortelli, Benedetta Del Secco, Ilaria Zanoni, Franco Belosi, Fabrizio Ravegnani, Alessia Nicosia, Magda Blosi and Anna Luisa Costa
Published in:
Nanomaterials, Issue 2021, 11(12), 3165, 2021, ISSN 2079-4991
Publisher:
Multidisciplinary Digital Publishing Institute
DOI:
10.3390/nano11123165
Author(s):
Antti Joonas Koivisto, Andrea Spinazzè, Frederik Verdonck, Francesca Borghi, Jakob Löndahl, Ismo Kalevi Koponen, Steven Verpaele, Michael Jayjock, Tareq Hussein, Jesus Lopez de Ipiña, Susan Arnold, Irini Furxhi
Published in:
Open Research Europe, Issue 2021, 1:72, 2021, ISSN 2732-5121
Publisher:
Open Research Europe
DOI:
10.12688/openreseurope.13752.1
Author(s):
Magda Blosi, Anna Luisa Costa, Simona Ortelli, Franco Belosi, Fabrizio Ravegnani, Alessio Varesano, Cinzia Tonetti, Ilaria Zanoni, Claudia Vineis
Published in:
Journal of Applied Polymer Science, Issue 138/46, 2021, Page(s) 51380, ISSN 0021-8995
Publisher:
John Wiley & Sons Inc.
DOI:
10.1002/app.51380
Author(s):
Furxhi Irini, Perucca Massimo, Blosi Magda, Lopez de Ipiña Jesús, Oliveira Juliana, Murphy Finbarr, Costa Anna Luisa
Published in:
Frontiers in Bioengineering and Biotechnology, 2022, ISSN 2296-4185
Publisher:
Frontiers
DOI:
10.3389/fbioe.2021.805096
Author(s):
Cazzagon V., Giubilato E., Bonetto A., Blosi M., Zanoni I., Costa A. L., Vineis C., Varesano A., Marcomini A., Hristozov D., Semenzin E., Badetti E.
Published in:
Frontiers Bioengineering and Biotechnology journal, 2022, ISSN 2296-4185
Publisher:
Frontiers
DOI:
10.3389/fbioe.2022.987650
Author(s):
"""Verónica I. Dumit, Ammar Ammar, Martine I. Bakker, Miguel A. Bañares, Cecilia Bossa, Anna Costa, Hilary Cowie, Damjana Drobne, Thomas E. Exner, Lucian Farcal, Steffi Friedrichs, Irini Furxhi, Roland Grafström, Andrea Haase, Martin Himly, Nina Jeliazkova, Iseult Lynch, Dieter Maier, Cornelle W. Noorlander, Hyun Kil Shin, Galo Soler-Illia, Blanca Suarez-Merino, Egon Willighagen, Penny Nymark"
Published in:
Nanotoday, 2023, ISSN 1748-0132
Publisher:
Elsevier BV
DOI:
10.1016/j.nantod.2023.101923
Author(s):
Irini Furxhi, Finbarr Murphy
Published in:
International Journal of Molecular Sciences, Issue 21/15, 2020, Page(s) 5280, ISSN 1422-0067
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/ijms21155280
Author(s):
Simona Ortelli, Maurizio Vespignani, Ilaria Zanoni,Magda Blosi, Claudia Vineis, Andreana Piancastelli, Stefania Albonetti, Anna Luisa Costa, Giovanni Baldi, Valentina Dami
Published in:
Molecules, 2023, ISSN 1420-3049
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/molecules28041863
Author(s):
Mahsa Mirzaei, Finbarr Murphy, Martin Mullins, Irini Furxhi
Published in:
Zenodo, 2023
Publisher:
Zenodo
DOI:
10.5281/zenodo.7754240
Searching for OpenAIRE data...
There was an error trying to search data from OpenAIRE
No results available