SUSTAINABLE PLANT PROTECTION TRANSITION: A GLOBAL HEALTH APPROACH

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Resultado final

PBPK models parameterized for A and H and back-calculated uptake of PPPs' mixture components based on biomonitoring data from CSS

D3.4 Validate exposure estimates, using biomonitoring at CSS, to assess the health impact on animals and humans. Lead: SRU. Other partners involved: WU, WR, UU.Existing PBPK models for animals (cow, chicken) and humans will be used for metabolites/degradation products for reverse dosimetry calculations of uptake of individual PPPs. These models will be refined using in vitro organoids to model kidney and liver function. Existing PBPK models will be complemented with a placenta module to estimate trans placental transport to the foetus. Parameters will be determined experimentally using an existing human placenta perfusion model (Schalkwijk et al., 2016). Existing human PBPK models will be parameterized and refined using data from controlled exposure of human volunteers by oral or dermal administration of single PPPs’ active ingredients at doses well below the acceptable daily intake (ADI). Approval for this study will be obtained from the local ethics board at RU. The PPP or corresponding metabolite content in blood, saliva and urine of animals and humans will be back-calculated to uptake using human and animal PBPK reverse dosimetry to verify external exposure model estimates in CSS. The influence of mixture components on the kinetic patterns of each of the individual PPPs will be estimated using animal data from WP4 to compare to existing biokinetic data in humans. The human PBPK modelling will result in more accurate estimates for single PPP exposures that will benefit quantitative in vitro to in vivo extrapolation (QIVIVE) in WP4. The biomonitoring findings from WP2 will be used to calibrate and validate the improved OBO model, integrating direct and indirect exposures of animal and human for the most relevant PPP mixtures at CSS locations.

Integrated fate models to estimate exposure of E and P for C-I-O farming systems using existing data and new data from the CSS

D3.2 Complement existing exposure data with new data from CSS to refine and enhance the validation status of existing model for ecosystems and plants. Lead: UCSC. Other partners involved: WU, UBERN, RU, UU.We will integrate fate models (FOCUS-PEARL, BREAM, IDEFICS, OPS-St) and methods to calculate internal exposure from external concentrations based on algorithms developed for BROWSE and PEARL-OPS models. Bioaccumulation in crops (P) and non-target species (E) will be calculated using improved existing fate models, existing datasets (task 3.1) and new data collected from CSS. We will calculate PPPs’ run-off to surface water using fate models (PRZM) for single-field-application and improve the existing PRZM model to extend these calculations to multiple fields in the catchment area. PPP percolation to groundwater will be modelled using fate models (PEARL) for single-field-application. A preliminary analysis will be done on dispersion in groundwater using CSS data (PELMO). GUTS/TKTD and DebTox models will be used to calculate uptake by non-target aquatic organisms

Ecotoxicological assessment of PPPs' mixtures on aquatic non-target species

D4.2 Ecotoxicological assessment of PPPs' mixtures on aquatic non-target speciesLead: MU and UAVR. Other partners involved: UH, WU, UBERN, DTU, AU, WR, CIEMAT.The mixtures will be tested on both terrestrial and aquatic species according to a tiered approach as recommended by the EFSA Draft guidance:Tier 1: Single-species standard assays with standard and new SPRINT indicator species – terrestrial; earthworms, collembolan, beneficial insects, plants and microorganisms; aquatic: freshwater algae, aquatic plants, insect’s larvae and fish – will be used to test the selected mixtures (see Table 1.6 for testing methods). The ecotoxicological data obtained for the mixture will be compared with the ecotoxicological data available for single compounds used in each mixture composition (EFSA database and scientific literature). This comparison will allow to discern for possible interactions. Whenever there is an unacceptable risk indicated in this first tier, the ecotoxicological assessment will proceed using more complex approaches.Tier 2: For the terrestrial ecosystem, multi-species microcosms (Šudoma 2019, Fojtová 2019) combining soil (including living microorganisms), native earthworms and plants (e.g. Lactuca sativa, Zea mays, Triticum aestivum) will be used to test the multi-species respond to the several PPPs mixtures. Survival and reproduction of earthworms, plant growth, microbial biomass and activity (Cmin, Nmin), bioaccumulation in earthworms, plants shoot/root, soil concentration development will be observed. Soil samples from the microcosms will be used by UH for further soil microbial analyses (enzymes involved in C-, N- and P-cycling as well as carbon and nitrogen stored in soil microorganisms using the fumigation extraction method). Among distinct parameters, biomarkers will be used as early-signals of exposure. For the aquatic ecosystem, a microcosm combining three distinct trophic levels will be implemented using a simplified trophic chain model, including a producer (microalgae), a first and a second order consumer, e.g. a benthic macroinvertebrate, and fish. Toxic-specific biomarkers will be measured as early-signals of exposure to PPPs (e.g. oxidative stress enzymes and lipid peroxidation)The multi-species microcosms will also be used to evaluate the potential for trophic transfer of PPPs. Terrestrial microcosms will allow to assess the transfer of PPPs to food-chain via earthworms (ecosystem) or via edible plants (human food and animal feed). Likewise, aquatic microcosms will allow to assess the transfer of PPPs from the producers to secondary consumers (ecosystem), or via fish consumption (human). The effects of the mixtures on mortality, reproductively and the gut microbiome of honey and wild bees will be tested in a laboratory experiment.

Gender equality reports

D92 Financial and legal management Lead WU This management task will cover i the preparation of a Consortium Agreement to regulate the management bodies the decisionmaking process and the management of IP and priorexisting knowledge ii the financial administration of the project ie the timely distribution of funding to the partners via a dedicated Euro account the budget management utilization and monitoring and the preparation of annual consortium consolidated financial statements and iii the preparation of periodic management reports including justification of costs and Form C of all beneficiaries Online reporting tools are envisioned to ensure efficient communication between project management and project partners

Integrated exposure model to estimate exposure of A and H for C-I-O farming scenarios using models calibrated with data from the CSS.

D3.3 Complement existing exposure data with new data from CSS to refine and enhance the validation status of existing models for animals and humans. Lead: UU. Other partners involved: AU, RU.Food Frequency Questionnaires (FFQ) and Split Portion Analyses (SPA) are used to collect data on recent consumption of PPPs’ residues from food patterns for conventional and organic farming scenarios. For indirect non-dietary exposure routes silicone wristbands are used to collect inhalation and skin exposure data relate to C-I-O farming systems. Information regarding activity patterns and indirect exposure to PPPs’ mixture residues from the ambient environment will be assessed in farmer’s families, non-farming rural and consumers subgroups using wearables such as silicon wristbands. Farm animals (cow, chicken, goat/sheep) also wear adapted low tech diffusive sampling devices. We will also study the cat as farm residential non-target species to reflects farm environment exposures relevant to both animals and humans. From conventional and organic farming scenarios the integrated scenario regarding dietary PPPs’ residues will be interpolated by calculation.

Literature review

D22 Literature review and collection of existing data on PPPs distribution and accumulation in ecosystems plants animals and humans Lead UBERN Other partners involved AU IISPV and CSS coordinators WU UBERN AU RAM UAVR UL INTA IPTPO UPCT MU UBORDA scoping review of existing literature on PPPs exposure and health effects will be performed as well as databases from running projects gather available CSS data and conduct semistructured interviews at CSS to support an integrated risk management tool for EPAH health based on EFSA work from 2019 httpswwwefsaeuropaeuenefsajournalpub5634 This review will be the platform for the development of an inventory of PPPs exposure as well as for the development of an integrated diagnostic approach The review will provide information on current knowledge knowns and identify gaps relevant to advancing the field unknowns

Minutes of the annual plenary meetings

D93 Gender balance Lead WU Other partners involved all First all partners will be informed about the unspoken societal rules which currently dictate the role of the gender aspects in research and innovation This step will include a statistical survey and an information session on gender issues during the kickoff meeting Furthermore we will initiate an inventory of gender equality among the CSS stakeholders to identify the number of women and men involved in the project including their positions roles ownership and opinions on the use of PPPs and alternative sustainable farming strategies Furthermore genderspecific PPPs effects will be considered in the global health approach examining the different effects of PPPs exposure on men and women both in the animal as well as human studies Therefore specific subgroup analyses will be performed based on underlying gender in WP2 WP3 and WP4

Assessment of the effects of PPPs' mixtures on human health.

D4.5: Assessment of the effects of PPPs’ mixtures on human health (M48; Lead: RAM).

Report on environmental and economic sustainability of pesticide use regimes

D6.1 Human and environmental health impacts and economic burden at the farm level. Lead: DTU. Other partners: UBERN, FIBL, AU, IISPV, RAM, UAVR, ECOLOGIC, WU, UL, INTA, IPTPO, UPCT, MU, UBORD. Environmental and economic impacts of C-I-O pesticide use are systematically identified and integrated, using farm-level survey data (WP1) and exposure and impact results from WP2-5. Pesticide productivity will be estimated for key crops using an econometric damage control approach. Relevant impact pathways are mapped and valuation schemes defined, differentiating populations to capture impact and cost variability. Indicator results will be compared across C-I-O scenarios. Instrumental variable or endogenous switching regression are used to quantify the impacts of farming practices on performance results. Matching or reweighting methods will be used to correct for selection bias.

Report on lock-ins and barriers

D7.1 Identify lock-ins and barriers in the existing farming systems and governance of PPP. Lead: ECOLOGIC. Other partners involved: CCRI, FIBL, DTU, WU, LQM, UBERN, AU, RAM, UAVR, CCRI, UL, INTA, IPTPO, UPCT, FAO, MU, UBORD. A systematic screening of the key lock-ins and barriers to the sustainable use of PPPs in existing farming and food systems and the governance mechanisms for PPP will be carried out with the help of a review of literature and policy documents, and interviews with stakeholders in the CSS, as well as on national and EU level. Interests, needs and views of farmers, farm advisors, regulators, policy makers and other societal actors related to lock-ins and barriers to more sustainable plant protection will be identified (including economic aspects). This includes farm-level lock-ins and barriers towards the wider uptake of pesticide reduction strategies (as identified in task 2.5), as well as more systemic lock-ins related to both input substitution and system redesign. The report will outline both commonalities applicable across the different farming systems, as well as specific barriers and lock-ins for the farming systems with critically high use of PPPs.

Three systematic reviews for modelling the exposure of PAH

D31 Mine existing data for modelling the fate of PPP used in CSS and the effect on PAH health leading to exposure datasets for each target group Lead IISPV Other partners involved RU UU DTUAn extensive review of main pathway of environmental fate of pesticide will be performed in soil water air and plant under different scenarios present in the CSS Environmental compartment identification per each pesticide used in each scenario where a potential risk could be present using ecotoxicological and toxicological endpoint values For exposure prevalence of humans an extensive data mining will be performed using contemporary systematic review methodology For animals cow chicken goatsheep crops plants and nontarget species ecosystem a scoping review will be performed and if feasible a full systematic review Existing data will be used and compared to model predictions generated by fate models see task 32 PPPs residues in food and feed products will be identified from existing databases as sources of direct dietary exposure

Report on external costs of pesticide use and of social overuse at farm level

D6.2 Health damages and external costs at the regional level, considering the wider life cycle impacts. Lead: DTU. Other partners: FIBL, UBERN, AU, IISPV, RAM, UAVR, ECOLOGIC, WU, UL, INTA, IPTPO, UPCT, MU, UBORD. Task 6.2 results are monetized using environmental accounting for different pesticide regimes and C-I-O scenarios, considering pesticide use aspects from WP2. To evaluate trade-offs, all related life cycle impacts are considered. Assumptions and background data are aligned to derive region-specific results at farm level to ensure a consistent integration with costs for farmers in line with WP5. Using adjustment factors, costs are ‘transferred’ to case study contexts. Pesticide productivity estimates from task 6.1 are used to derive private and social pesticide overuse, compared across scenarios, together with the external cost values for human and environmental impacts.

Report on the gender-specific analysis addressing distinct toxicological effects patterns of PPPs' mixtures in men vs. women

D4.6: Report on the gender-specific analysis addressing distinct toxicological effects patterns of PPPs’ mixtures in men vs. women (M48; Lead: RAM).

Ecotoxicological assessment of PPPs' mixtures on trophic transfer and bio-amplification of PPPs for both terrestrial and aquatic compartments

D4.3 Ecotoxicological assessment of PPPs' mixtures on trophic transfer and bio-amplification of PPPs for both terrestrial and aquatic compartmentsLead: MU and UAVR. Other partners involved: UH, WU, UBERN, DTU, AU, WR, CIEMAT.The mixtures will be tested on both terrestrial and aquatic species according to a tiered approach as recommended by the EFSA Draft guidance:Tier 1: Single-species standard assays with standard and new SPRINT indicator species – terrestrial; earthworms, collembolan, beneficial insects, plants and microorganisms; aquatic: freshwater algae, aquatic plants, insect’s larvae and fish – will be used to test the selected mixtures (see Table 1.6 for testing methods). The ecotoxicological data obtained for the mixture will be compared with the ecotoxicological data available for single compounds used in each mixture composition (EFSA database and scientific literature). This comparison will allow to discern for possible interactions. Whenever there is an unacceptable risk indicated in this first tier, the ecotoxicological assessment will proceed using more complex approaches.Tier 2: For the terrestrial ecosystem, multi-species microcosms (Šudoma 2019, Fojtová 2019) combining soil (including living microorganisms), native earthworms and plants (e.g. Lactuca sativa, Zea mays, Triticum aestivum) will be used to test the multi-species respond to the several PPPs mixtures. Survival and reproduction of earthworms, plant growth, microbial biomass and activity (Cmin, Nmin), bioaccumulation in earthworms, plants shoot/root, soil concentration development will be observed. Soil samples from the microcosms will be used by UH for further soil microbial analyses (enzymes involved in C-, N- and P-cycling as well as carbon and nitrogen stored in soil microorganisms using the fumigation extraction method). Among distinct parameters, biomarkers will be used as early-signals of exposure. For the aquatic ecosystem, a microcosm combining three distinct trophic levels will be implemented using a simplified trophic chain model, including a producer (microalgae), a first and a second order consumer, e.g. a benthic macroinvertebrate, and fish. Toxic-specific biomarkers will be measured as early-signals of exposure to PPPs (e.g. oxidative stress enzymes and lipid peroxidation)The multi-species microcosms will also be used to evaluate the potential for trophic transfer of PPPs. Terrestrial microcosms will allow to assess the transfer of PPPs to food-chain via earthworms (ecosystem) or via edible plants (human food and animal feed). Likewise, aquatic microcosms will allow to assess the transfer of PPPs from the producers to secondary consumers (ecosystem), or via fish consumption (human). The effects of the mixtures on mortality, reproductively and the gut microbiome of honey and wild bees will be tested in a laboratory experiment.

Generalized PPPs' application patterns from regional to EU level

D5.2 Data mining for upscaling. Lead: MU. Other partners involved: RU, WU, FAO, UU.The existing national and European data will be data-mined to model generalized PPPs’ application patterns from regional to European level. PPPs’ distribution will be modelled using environmental fate models and geographically relevant input data. Also, existing European monitoring data will be integrated to create European exposure maps on PPPs in the environment. A scoping exercise will be performed to improve understanding of effects from the exposure to PPP mixtures on human health and ecosystems.

Internal report on farm level impacts of different pesticide reduction strategies

D6.3 Performance and ranking of pesticide reduction strategies at farm level (ex-ante assessment). Lead: FIBL. Other partners: UBERN, AU, IISPV, RAM, UAVR, ECOLOGIC, WU, UL, INTA, IPTPO, UPCT, MU, DTU, UBORD. Selected pesticide use reduction strategies will be tested in task 6.3, consisting of: i) policy interventions such as taxes or subsidies, and ii) promising agronomic interventions or innovations emerging from the stakeholder dialogue in WP1. Agronomic interventions and innovations from WP1 and task 2.5 will in a first step be assessed ex-ante employing a farm-level simulation model. The effectiveness of each reduction strategy will be evaluated in terms of costs and benefits (policy costs, farm performance changes), as well as environmental impacts (EIQ, etc.), based on task 6.1. Interventions will also be designed to explicitly take into account pesticide risk information and thus target particularly harmful practices.

Testing and validation of the approach at CSS

D2.5 Identifying innovative and sustainable land management practices to reduce reliance on PPPs. Lead: UBERN. Other partners involved: FIBL, DTU, IISPV, RU, ECOL, and CSS coordinators - WU, UBERN, AU, RAM, UAVR, UL, INTA, IPTPO, UPCT, MU, UBORDThe main aim of this task is to identify ecological alternatives for sustainable plant protection by focusing on topics prioritized by the European Commission, such as the promotion of low-pesticide-input farming, or other management practices needed for farmers to implement Integrated Pest Management (IPM), and the Sustainable Use Directive (SUD). Selection of innovative techniques for mainstream farming systems will be based on knowledge gained from stakeholders (e.g., farm advisors, or technical authorities) in CSS (WP1) and data available from past and ongoing projects, such as iSQAPER (innovative agricultural management practices), SoilCare (soil improving cropping systems), and the WOCAT database (best practices), covering various pedo-climatic zones, soil types, and farming systems. A set of management strategies will be identified, including state-of-the-art IPM, organic production and/or other advances in agro-ecology including innovative techniques (e.g. cultural, physical, mechanical, and biological techniques) that have been shown to help reduce the use of PPPs while mitigating the effects of climatic change. Note: For the appropriate diagnosis of PPP distribution and health status, gender aspects will be taken into account when considering the literature reviews, testing and validation work on the integrated diagnostic approach.

Updated D&E plan

D83 Awareness raising and communication activities Lead CCRI Other partners involved all The communication strategy which is outlined in the Awareness raising and Communication plan ARC plan will identify strategic and targeted measures for promoting SPRINT and its results to society as a whole and in particular to some specific audiences and demonstrating how EU funding contributes to tackling food security To realise the ARC plan the following steps are proposed Launch of a dedicated public project website that is actively maintained for the promotion and dissemination of SPRINT activities results and other outputs task 81Multilingual project leaflets produced in English and the national language of the partner and CSS countriesNewsletters compiled and disseminated at 6month intervals Documentaryanimated videos and infographics will be developed to raise the public profile of the project and awareness on pesticide and food security issues Paper media and social media activities Participation in local events CSS stakeholders will be encouraged and empowered to act as active advocates in their respective region Side events at the FAOWHO Joint meeting of Pesticide Management JMPMIn addition each significant opportunity for engaging with the public through press releases radioTV interviews or newspapermagazine article will be explored proactively through contact with the respective WP leader and PRcommunication expert at the different participating institutions Creating dialogue with the general public will be take place using various tools eg videos channels eg social media and events eg university open days A full strategy will be prepared in the updated ARC plan by month 12 this will be continuously refined on which we will report in the formal periodic EC reports All communication activities will be actively monitored by the PSB with input from all partners

Monitoring plan for assessing EPAH health at CSS

D21 Monitoring plan for CSS and capacity building at stakeholder level Lead UBERN Other partners involved AU LQM DTU FIBL and CSS coordinators WU UBERN AU RAM UAVR UL INTA IPTPO UPCT MU UBORD This task involves the development of a harmonized monitoring plan to assess PPP distribution and related ecosystem plant animal and human health EPAH in 11 CSS and input parameters required in the exposure models The methodology will link to appropriate and standardized methods to be applied at all CSS in comparable fashion to ensure comparison between different sites across Europe Centralized training in all CSS will be organized to share experience and harmonize sample strategies and provide guidance on the consensus study protocol This study protocol will then be submitted for ethics approval in each of the regionscountries were CSS is planned see Chapter 5 Ethics for details The indicators for the monitoring plan will be selected based on a comprehensive coherent framework suited to assess the impacts of PPP residues aS Me Mi exposure and distribution We will investigate impacts in the ecological sociocultural and economic dimensions of sustainability The methodology will be tested using a multiactor approach during all major steps of the field study to ensure its applicability The monitoring strategy will be refined during the course of the project and updated after each seasonal assessment with the aim of enabling its continued use beyond the projects lifetime

Inventory of PPP distribution and accumulation in EPAH, incl gender-mediated differences

D2.3 Task 2.3: Data collection and analysis in the CSS following an integrated diagnostic approach. Lead: AU. Other partners involved: UBERN, WU, RU, VZZ, and CSS coordinators - WU, UBERN, AU, RAM, UAVR, UL, INTA, IPTPO, UPCT, MU, UBORD. The laboratory analysis will be conducted by WU, WR, HZG, CIEMAT, RU, UVAR, MU, UH, UCC.Data collection will be conducted in all CSS following the harmonized diagnostic approach with respect to PPP distribution in EPAH and the related health (details explained in Fig. 1.1). Additionally required input data are collected for modelling of exposure, and environmental fate. The timing of assessments and the methodology developed will be agreed among all partners prior to testing. The dominant mixtures PPPs present in the 11 CSS will be used as input for WP4 for (eco)toxicological tests. Results on EPAH health status and the potential impact of PPPs will be further studied in WP4.

SPRINT project website and secure intranet portal

D81 Set up project website and intranet portal for information Lead WU Other partners involved CCRIWU will establish a website for SPRINT through which the stakeholders and general public can be informed on SPRINT achievements and outputs or other newsworthy facts and a biannual newsletter The website will contain relevant information about the consortium the project and the relation to the funding programme and other projects in the same domain To facilitate adequate and protected dissemination of information eg scientific data announcements and registration for meetings and workshops management plan meeting agendasminutes tools for writing andor downloading project reports training materials WU will set up and maintain a secure intranet section which will be accessed only by the SPRINT partners and restricted users Specific mailing lists will enable targeted communication between the partners of the project and within WP Teams The project manager will maintain this website and intranet portal

Publicaciones

Considering degradation kinetics of pesticides in plant uptake models: proof of concept for potato

Autores: Zijian Li, Peter Fantke
Publicado en: Pest Management Science, Edición 79 (3), 2022, Página(s) 1154-1163, ISSN 1526-4998
Editor: Wiley
DOI: 10.1002/ps.7288

Screening of pesticide distributions in foods of animal origin: a matrix-based approach for biotransfer factor modeling of grazing mammals

Autores: Zijian Li; Jie Xiong; Peter Fantke
Publicado en: Environmental Science: Processes & Impacts, Edición 24 (4), 2022, Página(s) 609-624, ISSN 2050-7895
Editor: Royal Society of Chemistry
DOI: 10.1039/d1em00454a

Selected farm-level crop protection practices in Europe and Argentina: Opportunities for moving toward sustainable use of pesticides

Autores: Jennifer Mark, Peter Fantke, Farshad Soheilifard, Francisco Alcon, Josefa Contreras, Nelson Abrantes, Isabel Campos, Isabelle Baldi, Mathilde Bureau, Abdallah Alaoui, Florian Christ, Daniele Mandrioli, Daria Sgargi, Igor Pasković, Marija Polić Pasković, Matjaž Glavan, Jakub Hofman, Paula Harkes, Esperanza Huerta Lwanga, Trine Norgaard, Virginia Aparicio, Vivi Schlünssen, Anne Vested, Vera Sil
Publicado en: Journal of Cleaner Production, Edición 477, 2024, Página(s) 143577, ISSN 0959-6526
Editor: Elsevier BV
DOI: 10.1016/j.jclepro.2024.143577

Occurrence and distribution of pesticides and transformation products in ambient air in two European agricultural areas

Autores: Freya Debler, Nelson Abrantes, Paula Harkes, Isabel Campos, Juergen Gandrass
Publicado en: Science of The Total Environment, Edición 940, 2024, Página(s) 173705, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2024.173705

Toward Assessing Absolute Environmental Sustainability of Chemical Pollution

Autores: Kosnik MB, Hauschild MZ, Fantke P
Publicado en: Environmental Science & Technology, Edición March, 2022, ISSN 2328-8930
Editor: American Chemical Society
DOI: 10.1021/acs.est.1c06098

Effects of an organic diet intervention on the levels of organophosphorus metabolites in an adult cohort

Autores: Neus González, Carla Pàmies, Paula Martinez, Laura Martí, José L. Domingo, Martí Nadal, Montse Marquès
Publicado en: Food Research International, Edición 173, 2024, Página(s) 113354, ISSN 0963-9969
Editor: Elsevier BV
DOI: 10.1016/j.foodres.2023.113354

The role of public consultations in decision-making on future agricultural pesticide use: insights from European Union’s Farm to Fork Strategy public consultation

Autores: Frelih-Larsen A, Chivers C. A, Herb I, Mills J, Reed, M.
Publicado en: Journal of Environmental Policy and Planning, 2023, Página(s) 476-492, ISSN 1523-908X
Editor: Carfax Publishing Ltd.
DOI: 10.1080/1523908x.2023.2212369

Characterizing honey bee exposure and effects from pesticides for chemical prioritization and life cycle assessment

Autores: Crenna E, Jolliet O, Collina E, Sala S, Fantke P.
Publicado en: Environment International, Edición 138, 2020, ISSN 0160-4120
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2020.105642

Pesticide residues with hazard classifications relevant to non-target species including humans are omnipresent in the environment and farmer residences

Autores: Vera Silva, Lingtong Gai, Paula Harkes, Gaowei Tan, Coen J. Ritsema, Francisco Alcon, Josefa Contreras, Nelson Abrantes, Isabel Campos, Isabelle Baldi, Mathilde Bureau, Florian Christ, Daniele Mandrioli, Daria Sgargi, Igor Pasković, Marija Polić Pasković, Matjaž Glavan, Jakub Hofman, Esperanza Huerta Lwanga, Trine Norgaard, Violette Geissen
Publicado en: Environmental International, Edición 181, 2023, ISSN 1873-6750
Editor: Elsevier Ltd
DOI: 10.1016/j.envint.2023.108280

Toward harmonizing global pesticide regulations for surface freshwaters in support of protecting human health

Autores: Li Z, Fantke P.
Publicado en: Journal of Environmental Management, Edición 301, 2022, ISSN 0301-4797
Editor: Academic Press
DOI: 10.1016/j.jenvman.2021.113909

Pesticide exposure and the microbiota-gut-brain axis

Autores: Rie Matsuzaki; Eoin Gunnigle; Violette Geissen; Gerard Clarke; Jatin Nagpal; John F. Cryan
Publicado en: ISME Journal 17 (2023) 8, Edición 11, 2023, ISSN 1751-7370
Editor: Springer Nature
DOI: 10.1038/s41396-023-01450-9

Pesticide pollution in argentine drinking water: A call to ensure safe access

Autores: Aparicio V, De Geronimo E
Publicado en: Environmental Challenges, Edición Volume 14, 2024, Página(s) 100808, ISSN 2667-0100
Editor: Elsevier
DOI: 10.1016/j.envc.2023.100808

Glyphosate, glufosinate ammonium, and AMPA occurrences and sources in groundwater of hilly vineyards

Autores: Nicoleta Suciu, Elisabetta Russo, Maura Calliera, Gian Piero Luciani, Marco Trevisan, Ettore Capri
Publicado en: Science of the Total Environment, Edición 866, 2023, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2022.161171

Chronic Interstitial Nephritis in Agricultural Communities: A Patient in Paraguay

Autores: Walter E. Cabrera J, Benjamin A. Vervaet, Gerd Schreurs, Cynthia C. Nast, Francisco Santa-Cruz, Marc E. De Broe
Publicado en: Kidney International Reports, Edición 7, 2022, Página(s) 1131-1135, ISSN 2468-0249
Editor: Elsevier
DOI: 10.1016/j.ekir.2022.02.019

Occurrence of pesticide residues in indoor dust of farmworker households across Europe and Argentina

Autores: Irene Navarro,Adrian de la Torre, Paloma Sanz, Isabelle Baldi, Paula Harkes, Esperanza Huerta-Lwanga, Trine Nørgaard, Matjaˇz Glavan, Igor Paskovic, Marija Polic Paskovic, Nelson Abrante, Isabel Campos, Francisco Alcon, Josefina Contrerasj, Abdallah Alaoui, Jakub Hofman, Anne Vested, Mathilde Bureau, Virginia Aparicio, Daniele Mandriol, Daria Sgargi, Hans Mol, Violette Geissen, Vera Silva, Marí
Publicado en: Science of the Total Environment, Edición 905, 2023, Página(s) 167797, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2023.167797

Introducing ground cover management in pesticide emission modeling

Autores: Céline Gentil-Sergent; Claudine Basset-Mens; Christel Renaud-Gentié; Charles Mottes; Carlos Manuel Moraleda Melero; Arthur Launay; Peter Fantke
Publicado en: Integrated Environmental Assessment and Management, Edición 18 (1), 2021, Página(s) 274-288, ISSN 1551-3777
Editor: Society of Environmental Toxicology and Chemistry
DOI: 10.1002/ieam.4482

Framework for defining pesticide maximum residue levels in feed: applications to cattle and sheep

Autores: Peter Fantke; Zijian Li
Publicado en: Pest Management Science, Edición 79 (2), 2023, Página(s) 748-759, ISSN 1526-4998
Editor: John Wiley and Sons Ltd
DOI: 10.1002/ps.7241

Including the bioconcentration of pesticide metabolites in plant uptake modeling

Autores: Zijian Li, Peter Fantke
Publicado en: Environmental Science: Processes & Impacts, Edición 25, 2024, Página(s) 1708-1717, ISSN 2050-7887
Editor: Royal Society of Chemistry
DOI: 10.1039/d3em00266g

Towards a more comprehensive life cycle assessment framework for assessing toxicity-related impacts for livestock products: The case of Danish pork

Autores: Dorca-Preda T, Fantke P, Mogensen L, Knudsen MT.
Publicado en: Science of the Total Environment, Edición January, 2022, ISSN 0048-9697
Editor: Elsevier BV
DOI: 10.1016/j.scitotenv.2021.152811

Quantifying pesticide emission fractions for tropical conditions

Autores: Gentil-Sergent C, Basset-Mens C, Gaab J, Mottes C, Melero C, Fantke P.
Publicado en: Chemosphere, Edición 275, 2021, ISSN 0045-6535
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.chemosphere.2021.130014

Improved plant bioconcentration modeling of pesticides: The role of periderm dynamics

Autores: Xiao S, Li Z, Fantke P.
Publicado en: Pest Management Science, Edición 77 (11), 2021, Página(s) 5096-5108, ISSN 1526-498X
Editor: John Wiley & Sons Inc.
DOI: 10.1002/ps.6549

Development of an analytical method for the determination of more than 300 pesticides and metabolites in the particulate and gaseous phase of ambient air

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DOI: 10.1007/s00216-024-05254-4

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DOI: 10.1016/j.scitotenv.2021.152344

Data-Driven Characterization of Genetic Variability in Disease Pathways and Pesticide-Induced Nervous System Disease in the United States Population

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DOI: 10.1289/ehp14108

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DOI: 10.1016/j.envpol.2024.124926

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Editor: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107610

Collection of human and environmental data on pesticide use in Europe and Argentina: Field study protocol for the SPRINT project.

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Editor: Public Library of Science
DOI: 10.1371/journal.pone.0259748

Natural soils in OECD 222 testing — influence of soil water and soil properties on earthworm reproduction toxicity of carbendazim

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Editor: Kluwer Academic Publishers
DOI: 10.1007/s10646-023-02636-9

Environmental and human health at risk – Scenarios to achieve the Farm to Fork 50% pesticide reduction goals

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Publicado en: Environment International, Edición 165, 2022, ISSN 0160-4120
Editor: Pergamon Press Ltd.
DOI: 10.1016/j.envint.2022.107296

Indirect Effects of the Herbicide Glyphosate on Plant, Animal and Human Health Through its Effects on Microbial Communities

Autores: Van Bruggen AH, Finckh MR, He M, Ritsema CJ, Harkes P, Knuth D, Geissen V.
Publicado en: Frontiers in Environmental Science, Edición 9, 2021, ISSN 2296-665X
Editor: Frontiers Media S.A
DOI: 10.3389/fenvs.2021.763917

Assessing pesticide residues occurrence and risks in water systems: A Pan-European and Argentina perspective

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Publicado en: Water Research, Edición 254, 2024, Página(s) 121419, ISSN 0043-1354
Editor: Elsevier BV
DOI: 10.1016/j.watres.2024.121419

Coupling pesticide emission and toxicity characterization models for LCA: Application to open-field tomato production in Martinique

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Publicado en: Journal of Cleaner Production, Edición 277, 2020, ISSN 0959-6526
Editor: Elsevier BV
DOI: 10.1016/j.jclepro.2020.124099

Pesticide Residues in Organic and Conventional Agricultural Soils across Europe: Measured and Predicted Concentrations

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Publicado en: Environmental Science & Technology, Edición 58, 2024, Página(s) 6744-6752, ISSN 0013-936X
Editor: American Chemical Society
DOI: 10.1021/acs.est.3c09059

Improving Pesticide Uptake Modeling into Potatoes: Considering Tuber Growth Dynamics

Autores: Xiao S, Gong Y, Li Z, Fantke P.
Publicado en: Journal of Agricultural and Food Chemistry, Edición 69 (12), 2021, Página(s) 3607-3616, ISSN 0021-8561
Editor: American Chemical Society
DOI: 10.1021/acs.jafc.1c00151

Dissipation kinetics, residue modeling and human intake of endosulfan applied to okra (Abelmoschus esculentus)

Autores: Ravinder Nath, G. Komala, Peter Fantke, Santanu Mukherjee
Publicado en: Science of The Total Environment, Edición 835, 2022, ISSN 1879-1026
Editor: Elsevier
DOI: 10.1016/j.scitotenv.2022.155591

Identifying and Comparing Easily Accessible Frameworks for Assessing Soil Organic Matter Functioning

Autores: Lúcia Barão, Abdallah Alaoui, Rudi Hessel
Publicado en: Agronomy, Edición 13 (1), 2023, Página(s) 109, ISSN 2073-4395
Editor: MDPI
DOI: 10.3390/agronomy13010109

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