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Dynamic adaptive microscopy for label-free multi-parametric imaging in biology and medicine

Project description

Deeper in vivo imaging thanks to improved optical microscopy techniques

Although optical microscopy has been extensively used in medical imaging, its use in in vivo studies presents a number of challenges. First, the diffusing nature of light propagation in tissues limits in vivo microscopy to superficial depths. Second, the invasive fluorescent tags allow monitoring of only 1-5 events; this performance is far below the targets set by functional genomics and proteomics. The EU-funded DynAMic project will address these two fundamental limitations. Use of wavefront-shaping adaptive optics will improve the performance of optical systems, while inversion light diffusion techniques will help it reach 10 times deeper into tissue. In addition, advanced image formation techniques will radically improve label-free high-contrast imaging. The new techniques will be tested in ophthalmic imaging.

Call for proposal

H2020-FETOPEN-2018-2020

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Sub call

H2020-FETOPEN-2018-2019-2020-01

Coordinator

IDRYMA TECHNOLOGIAS KAI EREVNAS
Net EU contribution
€ 669 800,00
Address
N Plastira Str 100
70013 Irakleio
Greece

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Region
Ηράκλειο Κρήτη Νησιά Αιγαίου
Activity type
Research Organisations
Other funding
€ 0,00

Participants (8)

TECHNISCHE UNIVERSITAET MUENCHEN
Germany
Net EU contribution
€ 697 092,50
Address
Arcisstrasse 21
80333 Muenchen

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Region
Bayern Oberbayern München, Kreisfreie Stadt
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE CNRS
France
Net EU contribution
€ 515 940,65
Address
Rue Michel Ange 3
75794 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Research Organisations
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

ECOLE NORMALE SUPERIEURE
France
Net EU contribution
€ 58 387,50
Address
45, Rue D'ulm
75230 Paris Cedex 05

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Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Third-party

Legal entity other than a subcontractor which is affiliated or legally linked to a participant. The entity carries out work under the conditions laid down in the Grant Agreement, supplies goods or provides services for the action, but did not sign the Grant Agreement. A third party abides by the rules applicable to its related participant under the Grant Agreement with regard to eligibility of costs and control of expenditure.

SORBONNE UNIVERSITE
France
Net EU contribution
€ 22 968,10
Address
21 Rue De L'ecole De Medecine
75006 Paris

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Region
Ile-de-France Ile-de-France Paris
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
THE UNIVERSITY COURT OF THE UNIVERSITY OF ST ANDREWS
United Kingdom
Net EU contribution
€ 584 516,25
Address
North Street 66 College Gate
KY16 9AJ St Andrews

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Region
Eastern Scotland Clackmannanshire and Fife
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
EBERHARD KARLS UNIVERSITAET TUEBINGEN
Germany
Net EU contribution
€ 415 875,00
Address
Geschwister-scholl-platz
72074 Tuebingen

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Region
Baden-Württemberg Tübingen Tübingen, Landkreis
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
RAYFOS LTD
United Kingdom
Net EU contribution
€ 493 657,50
Address
Winton House Winton Square
RG21 8EN Basingstoke

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
South East (England) Hampshire and Isle of Wight North Hampshire
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00
IMAGINE OPTIC
France
Net EU contribution
€ 498 900,00
Address
18 Rue Charles De Gaulle
91400 Orsay

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SME

The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed.

Yes
Region
Ile-de-France Ile-de-France Essonne
Activity type
Private for-profit entities (excluding Higher or Secondary Education Establishments)
Other funding
€ 0,00