A novel, efficient and minimally invasive medical procedure to treat anastomotic leakage during colorectal cancer surgery.

Información del proyecto

CTI

Identificador del acuerdo de subvención: 863492

DOI

10.3030/863492

Proyecto cerrado

Fecha de la firma de la CE 27 Mayo 2019

Fecha de inicio 1 Mayo 2019

Fecha de finalización 31 Agosto 2019

Financiado con arreglo a

• INDUSTRIAL LEADERSHIP - Innovation In SMEs

Coste total

€ 71 429,00

Aportación de la UE

€ 50 000,00

Coordinado por

TECNOLINE SPA
Italy

Periodic Reporting for period 1 - CTI (A novel, efficient and minimally invasive medical procedure to treat anastomotic leakage during colorectal cancer surgery.)

Período documentado: 2019-05-01 hasta 2019-08-31

Resumen del contexto y de los objetivos generales del proyecto

When patients are diagnosed with rectal cancer, they undergo surgery to remove the tumor and, in doing so, a section of the rectum is also removed. In order to eliminate waste normally, an anastomosis is performed, i.e. the remaining healthy parts of the colon are reconnected. One of the major adverse events that can take place following this surgery is an anastomotic leakage, to prevent this a temporary ileostomies used to reduce the risk of anastomotic leakage. Once the rectum has healed from the tumor removal, the ileostomy may be reversed. We have developed CTI, to be used in tube ileostomy, as alternative of the current practices. After the rectal tumor is removed during surgery, CTI is implanted in order to perform a tube ileostomy. Since CTI can be used instead of a loop ileostomy, a stoma does not need to be created and the complications associated with it are avoided. Approximately 8–11 days after implanting CTI, it is can be removed and discharged. By using CTI can save the health care system 30% of direct cost and within the Eu this translate to about €330M. More importantly using CTI will provide patients better health outcomes because they have faster recovery and lower risk of infection.

Trabajo realizado desde el comienzo del proyecto hasta el final del período abarcado por el informe y los principales resultados hasta la fecha

We have assessed the technical viability of CTI and performed a detailed market analysis, verifying the commercial potential to support our go to market activities. The financial viability plan indicates a total investment for Phase 2 project of €1.9 million will be needed. Allowing us to go into the market in 2022. We have identified the barriers for entry and we are currently working to expand our medical advisory board to support our development.

Avances que van más allá del estado de la técnica e impacto potencial esperado (incluida la repercusión socioeconómica y las implicaciones sociales más amplias del proyecto hasta la fecha)

The impact of our devices on healthcare can be dramatic we can reduce 30% in direct health care cost will allowing patients to have shorter recovery time and lowering their risks of infection. CTI includes a medical-grade silicone tube, inside which a metal spiral is inserted to guarantee the non-occlusion of waste passage. This will be the only product on the market that is specifically designed for tube ileostomy and we are working with leading key opinion leaders to finalized the design to ensure adoption of new technique will be seamless.

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