Deciphering the impact of exposures from the gut microbiome-derived molecular complex in human health and disease

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Functional prediction of proteins from the human gut archaeome

Author(s): Polina V Novikova, Susheel Bhanu Busi, Alexander J Probst, Patrick May, Paul Wilmes
Published in: ISME Communications, Issue 4, 2024, ISSN 2730-6151
Publisher: Oxford University Press (OUP)
DOI: 10.1093/ismeco/ycad014

Ketogenic diet suppresses colorectal cancer through the gut microbiome long chain fatty acid stearate

Author(s): Mina Tsenkova, Madita Brauer, Vitaly Igorevich Pozdeev, Marat Kasakin, Susheel Bhanu Busi, Maryse Schmoetten, Dean Cheung, Marianne Meyers, Fabien Rodriguez, Anthoula Gaigneaux, Eric Koncina, Cedric Gilson, Lisa Schlicker, Diran Herebian, Martine Schmitz, Laura de Nies, Ertan Mayatepek, Serge Haan, Carine de Beaufort, Thorsten Cramer, Johannes Meiser, Carole L. Linster, Paul Wilmes, Elisabeth Lete
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-56678-0

Multiomics approaches disclose very-early molecular and cellular switches during insect-venom allergen-specific immunotherapy: an observational study

Author(s): Dimitrii Pogorelov, Sebastian Felix Nepomuk Bode, Xin He, Javier Ramiro-Garcia, Fanny Hedin, Wim Ammerlaan, Maria Konstantinou, Christophe M. Capelle, Ni Zeng, Aurélie Poli, Olivia Domingues, Guillem Montamat, Oliver Hunewald, Séverine Ciré, Alexandre Baron, Joseph Longworth, Agnieszka Demczuk, Murilo Luiz Bazon, Ingrid Casper, Ludger Klimek, Lorie Neuberger-Castillo, Dominique Revets, Lea Guyo
Published in: Nature Communications, Issue 15, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-024-54684-2

Personalized modeling of gut microbiome metabolism throughout the first year of life

Author(s): Rola Shaaban, Susheel Bhanu Busi, Paul Wilmes, Jean-Louis Guéant, Almut Heinken
Published in: Communications Medicine, Issue 4, 2024, ISSN 2730-664X
Publisher: Springer Nature
DOI: 10.1038/s43856-024-00715-4

Altered infective competence of the human gut microbiome in COVID-19

Author(s): Laura de Nies, Valentina Galata, Camille Martin-Gallausiaux, Milena Despotovic, Susheel Bhanu Busi, Chantal J. Snoeck, Lea Delacour, Deepthi Poornima Budagavi, Cedric Christian Laczny, Janine Habier, Paula-Cristina Lupu, Rashi Halder, Joëlle V. Fritz, Taina Marques, Estelle Sandt, Marc Paul O’Sullivan, Soumyabrata Ghosh, Venkata Satagopam, CON-VINCE Consortium, Rejko Krüger, Guy Fagherazzi, Ma
Published in: Microbiome, 2023, ISSN 2049-2618
Publisher: Springer Nature
DOI: 10.1186/s40168-023-01472-7

SARS-CoV-2 transmission in educational settings during an early summer epidemic wave in Luxembourg, 2020

Author(s): Joël Mossong, Laurent Mombaerts, Lisa Veiber, Jessica Pastore, Gwenaëlle Le Coroller, Michael Schnell, Silvana Masi, Laetitia Huiart, Paul Wilmes
Published in: BMC Infectious Diseases, 2021, ISSN 1471-2334
Publisher: BioMed Central
DOI: 10.1186/s12879-021-06089-5

Critical Assessment of MetaProteome Investigation (CAMPI): a multi-laboratory comparison of established workflows

Author(s): Tim Van Den Bossche, Benoit J. Kunath, Kay Schallert, Stephanie S. Schäpe, Paul E. Abraham, Jean Armengaud, Magnus Ø. Arntzen, Ariane Bassignani, Dirk Benndorf, Stephan Fuchs, Richard J. Giannone, Timothy J. Griffin, Live H. Hagen, Rashi Halder, Céline Henry, Robert L. Hettich, Robert Heyer, Pratik Jagtap, Nico Jehmlich, Marlene Jensen, Catherine Juste, Manuel Kleiner, Olivier Langella, Theresa
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27542-8

Challenges, Strategies, and Perspectives for Reference-Independent Longitudinal Multi-Omic Microbiome Studies

Author(s): Susana Martínez Arbas, Susheel Bhanu Busi, Pedro Queirós, Laura de Nies, Malte Herold, Patrick May, Paul Wilmes, Emilie E. L. Muller, Shaman Narayanasamy
Published in: Frontiers in Genetics, 2021, ISSN 1664-8021
Publisher: Frontiers Media
DOI: 10.3389/fgene.2021.666244

Integration of multiple flexible electrodes for real-time detection of barrier formation with spatial resolution in a gut-on-chip system

Author(s): Mara Lucchetti, Gabriel Werr, Sofia Johansson, Laurent Barbe, Léa Grandmougin, Paul Wilmes, Maria Tenje
Published in: Microsystems & Nanoengineering, Issue 10, 2024, ISSN 2055-7434
Publisher: Nature Publishing Group
DOI: 10.1038/s41378-023-00640-x

Education as Risk Factor of Mild Cognitive Impairment: The Link to the Gut Microbiome

Author(s): Matthias Klee, V.T.E. Aho, P. May, A. Heintz-Buschart, Z. Landoulsi, S.R. Jónsdóttir, C. Pauly, L. Pavelka, L. Delacour, A. Kaysen, R. Krüger, P. Wilmes, A.K. Leist, Geeta Acharya, Gloria Aguayo, Myriam Alexandre, Muhammad Ali, Wim Ammerlann, Giuseppe Arena, Michele Bassis, Roxane Batutu, Katy Beaumont, Sibylle Béchet, Guy Berchem, Alexandre Bisdorff, Ibrahim Boussaad, David Bouvier, Lorieza C
Published in: The Journal of Prevention of Alzheimer's Disease, Issue 11, 2025, Page(s) 759-768, ISSN 2274-5807
Publisher: Elsevier Ltd.
DOI: 10.14283/jpad.2024.19

The gut microbial metabolite formate exacerbates colorectal cancer progression

Author(s): Dominik Ternes, Mina Tsenkova, Vitaly Igorevich Pozdeev, Marianne Meyers, Eric Koncina, Sura Atatri, Martine Schmitz, Jessica Karta, Maryse Schmoetten, Almut Heinken, Fabien Rodriguez, Catherine Delbrouck, Anthoula Gaigneaux, Aurelien Ginolhac, Tam Thuy Dan Nguyen, Lea Grandmougin, Audrey Frachet-Bour, Camille Martin-Gallausiaux, Maria Pacheco, Lorie Neuberger-Castillo, Paulo Miranda, Nikolaus Zue
Published in: Nature Metabolism, Issue 4, 2023, Page(s) 458-475, ISSN 2522-5812
Publisher: Springer Nature
DOI: 10.1038/s42255-022-00558-0

SARS-CoV-2 transmission risk from asymptomatic carriers: Results from a mass screening programme in Luxembourg

Author(s): Paul Wilmes, Jacques Zimmer, Jasmin Schulz, Frank Glod, Lisa Veiber, Laurent Mombaerts, Bruno Rodrigues, Atte Aalto, Jessica Pastore, Chantal J. Snoeck, Markus Ollert, Guy Fagherazzi, Joel Mossong, Jorge Goncalves, Alexander Skupin, Ulf Nehrbass
Published in: The Lancet Regional Health - Europe, 2021, ISSN 2666-7762
Publisher: Elsevier Ltd.
DOI: 10.1016/j.lanepe.2021.100056

Gut microbiome is not associated with mild cognitive impairment in Parkinson’s disease

Author(s): Velma T. E. Aho, Matthias Klee, Zied Landoulsi, Anna Heintz-Buschart, Lukas Pavelka, Anja K. Leist, Rejko Krüger, Patrick May, Paul Wilmes, null null, Geeta Acharya, Gloria Aguayo, Myriam Alexandre, Muhammad Ali, Wim Ammerlann, Giuseppe Arena, Michele Bassis, Roxane Batutu, Katy Beaumont, Sibylle Béchet, Guy Berchem, Alexandre Bisdorff, Ibrahim Boussaad, David Bouvier, Lorieza Castillo, Gessica
Published in: npj Parkinson's Disease, Issue 10, 2024, ISSN 2373-8057
Publisher: Nature Publishing Group
DOI: 10.1038/s41531-024-00687-1

binny: an automated binning algorithm to recover high-quality genomes from complex metagenomic datasets

Author(s): Oskar Hickl, Pedro Queirós, Paul Wilmes, Patrick May, Anna Heintz-Buschart
Published in: Briefings in Bioinformatics, 2022, ISSN 1467-5463
Publisher: Oxford University Press
DOI: 10.1093/bib/bbac431

Alterations of oral microbiota and impact on the gut microbiome in type 1 diabetes mellitus revealed by integrated multi-omic analyses

Author(s): Benoit J. Kunath, Oskar Hickl, Pedro Queirós, Camille Martin-Gallausiaux, Laura A. Lebrun, Rashi Halder, Cedric C. Laczny, Thomas Sebastian B. Schmidt, Matthey R. Hayward, Dörte Becher, Anna Heintz-Buschart, Carine de Beaufort, Peer Bork, Patrick May, Paul Wilmes
Published in: Microbiome, 2022, ISSN 2049-2618
Publisher: Springer Nature
DOI: 10.1186/s40168-022-01435-4

Protocol for a multicentre cross-sectional, longitudinal ambulatory clinical trial in rheumatoid arthritis and Parkinson’s disease patients analysing the relation between the gut microbiome, fasting and immune status in Germany (ExpoBiome)

Author(s): Bérénice Hansen, Cédric C Laczny, Velma T E Aho, Audrey Frachet-Bour, Janine Habier, Marek Ostaszewski, Andreas Michalsen, Etienne Hanslian, Daniela A Koppold, Anika M Hartmann, Nico Steckhan, Brit Mollenhauer, Sebastian Schade, Kirsten Roomp, Jochen G Schneider, Paul Wilmes
Published in: BMJ Open, 2023, ISSN 2044-6055
Publisher: BMJ Publishing Group
DOI: 10.1136/bmjopen-2022-071380

Metagenomic Profiling of Oral Microbiome Dynamics During Chemoradiotherapy in Head and Neck Squamous Cell Carcinoma Patients

Author(s): Dominique A. Torozan, Cédric Christian Laczny, Kirsten Roomp, Paul Wilmes, Jochen Fleckenstein, Jochen G. Schneider
Published in: Cancer Medicine, Issue 14, 2025, ISSN 2045-7634
Publisher: Wiley
DOI: 10.1002/cam4.70589

Bacteroides acidifaciens: Linking dietary fiber to liver health

Author(s): Viacheslav A. Petrov, Cédric C. Laczny, Paul Wilmes
Published in: Cell Metabolism, Issue 36, 2024, Page(s) 1908-1910, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2024.08.002

The benefits, costs and feasibility of a low incidence COVID-19 strategy

Author(s): Thomas Czypionka, Emil N Iftekhar, Barbara Prainsack, Viola Priesemann, Simon Bauer, André Calero Valdez, Sarah Cuschieri , Enrico Glaab , Eva Grill , Jenny Krutzinna, Christos Lionis, Helena Machado, Carlos Martins, George N Pavlakis, Matjaž Perc, Elena Petelos, Martyn Pickersgill, Alexander Skupin, Eva Schernhammer, Ewa Szczurek, Sotirios Tsiodras, Peter Willeit, Paul Wilmes
Published in: The Lancet Regional Health - Europe, 2022, ISSN 2666-7762
Publisher: Elsevier Ltd.
DOI: 10.1016/j.lanepe.2021.100294

From animal models to gut-on-chip: the challenging journey to capture inter-individual variability in chronic digestive disorders

Author(s): Aicha Kriaa, Vincent Mariaule, Charlotte De Rudder, Amin Jablaoui, Harry Sokol, Paul Wilmes, Emmanuelle Maguin, Moez Rhimi
Published in: Gut Microbes, Issue 16, 2024, ISSN 1949-0976
Publisher: Landes Bioscience
DOI: 10.1080/19490976.2024.2333434

Toward hypothesis-driven, personalized microbiome screening

Author(s): Catherine Sedrani, Paul Wilmes
Published in: Cell Reports Methods, 2022, ISSN 2667-2375
Publisher: Cell Press Elsevier Inc.
DOI: 10.1016/j.crmeth.2021.100139

Mobilome-driven segregation of the resistome in biological wastewater treatment.

Author(s): Laura de Nies, Susheel Bhanu Busi, Benoit Josef Kunath, Patrick May, Paul Wilmes
Published in: eLife, 2022, ISSN 2050-084X
Publisher: eLife Sciences Publications
DOI: 10.7554/elife.81196

The Metaproteomics Initiative: a coordinated approach for propelling the functional characterization of microbiomes

Author(s): Tim Van Den Bossche, Magnus Ø. Arntzen, Dörte Becher, Dirk Benndorf, Vincent G. H. Eijsink, Céline Henry, Pratik D. Jagtap, Nico Jehmlich, Catherine Juste, Benoit J. Kunath, Bart Mesuere, Thilo Muth, Phillip B. Pope, Jana Seifert, Alessandro Tanca, Sergio Uzzau, Paul Wilmes, Robert L. Hettich, Jean Armengaud
Published in: Microbiome, 2021, ISSN 2049-2618
Publisher: Springer Nature
DOI: 10.1186/s40168-021-01176-w

Persistence of birth mode-dependent effects on gut microbiome composition, immune system stimulation and antimicrobial resistance during the first year of life

Author(s): Susheel Bhanu Busi, Laura de Nies, Janine Habier, Linda Wampach, Joëlle V Fritz, Anna Heintz-Buschart, Patrick May, Rashi Halder, Carine de Beaufort, Paul Wilmes
Published in: ISME Communications, Issue 1, 2024, ISSN 2730-6151
Publisher: Oxford University Press (OUP)
DOI: 10.1038/s43705-021-00003-5

Snapshot: The Expobiome Map

Author(s): Velma T. E. Aho, Marek Ostaszewski, Camille Martin-Gallausiaux, Cedric C. Laczny, Jochen G. Schneider, Paul Wilmes
Published in: Cell Host & Microbe, 2022, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2022.08.015

Functional meta-omics provide critical insights into long- and short-read assemblies

Author(s): Valentina Galata, Susheel Bhanu Busi, Benoît Josef Kunath, Laura de Nies, Magdalena Calusinska, Rashi Halder, Patrick May, Paul Wilmes, Cedric Christian Laczny
Published in: Briefings in Bioinformatics, 2021, ISSN 1467-5463
Publisher: Oxford University Press
DOI: 10.1093/bib/bbab330

Fiber deprivation and microbiome-borne curli shift gut bacterial populations and accelerate disease in a mouse model of Parkinson’s disease

Author(s): Kristopher J. Schmit, Pierre Garcia, Alessia Sciortino, Velma T.E. Aho, Beatriz Pardo Rodriguez, Mélanie H. Thomas, Jean-Jacques Gérardy, Irati Bastero Acha, Rashi Halder, Camille Cialini, Tony Heurtaux, Irina Ostahi, Susheel B. Busi, Léa Grandmougin, Tuesday Lowndes, Yogesh Singh, Eric C. Martens, Michel Mittelbronn, Manuel Buttini, Paul Wilmes
Published in: Cell Reports, 2023, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2023.113071

PathoFact: a pipeline for the prediction of virulence factors and antimicrobial resistance genes in metagenomic data.

Author(s): Laura de Nies, Sara Lopes, Susheel Bhanu Busi, Valentina Galata, Anna Heintz-Buschart, Anna Heintz-Buschart, Cedric Christian Laczny, Patrick May, Paul Wilmes
Published in: Microbiome, 2021, ISSN 2049-2618
Publisher: Springer Nature
DOI: 10.1186/s40168-020-00993-9

Multi-Omics Analysis of Mouse Fecal Microbiome Reveals Supplier-Dependent Functional Differences and Novel Metagenome-Assembled Genomes

Author(s): Zachary L. McAdams, Susheel Bhanu Busi, Kevin L. Gustafson, Nathan Bivens, Craig L. Franklin, Paul Wilmes, Aaron C. Ericsson
Published in: Applied Microbiology, Issue 4, 2025, Page(s) 1600-1615, ISSN 2673-8007
Publisher: MDPI
DOI: 10.3390/applmicrobiol4040109

The gut microbiome molecular complex in human health and disease

Author(s): Paul Wilmes, Camille Martin-Gallausiaux, Marek Ostaszewski, Velma T. E. Aho, Polina Novikova, Cedric C. Laczny, Jochen Schneider
Published in: Cell Host & Microbe, 2022, ISSN 1931-3128
Publisher: Cell Press
DOI: 10.1016/j.chom.2022.08.016

Generalisation of COVID-19 incidences provides a biased view of the actual epidemiological situation

Author(s): Paul Wilmes, Joel Mossong, Thomas G. Dentzer
Published in: The Lancet Regional Health - Europe, 2021, ISSN 2666-7762
Publisher: Elsevier Ltd.
DOI: 10.1016/j.lanepe.2021.100116

Forecasting the dynamics of a complex microbial community using integrated meta-omics

Author(s): Francesco Delogu, Benoit J. Kunath, Pedro M. Queirós, Rashi Halder, Laura A. Lebrun, Phillip B. Pope, Patrick May, Stefanie Widder, Emilie E. L. Muller, Paul Wilmes
Published in: Nature Ecology & Evolution, 2023, ISSN 2397-334X
Publisher: Springer Nature
DOI: 10.1038/s41559-023-02241-3

The impact of fasting and caloric restriction on rheumatoid arthritis in humans: A narrative review

Author(s): Bérénice Hansen, Marta Sánchez-Castro, Lynn Schintgen, Arefeh Khakdan, Jochen G. Schneider, Paul Wilmes
Published in: Clinical Nutrition, Issue 49, 2025, Page(s) 178-186, ISSN 0261-5614
Publisher: Churchill Livingstone
DOI: 10.1016/j.clnu.2025.04.025

A Gut-on-a-Chip Model to Study the Gut Microbiome-Nervous System Axis

Author(s): Catherine Sedrani, Gemma Gomez-Giro, Léa Grandmougin, Jens Christian Schwamborn, Paul Wilmes
Published in: JoVE, 2023, ISSN 1940-087X
Publisher: MYJoVE Corporation
DOI: 10.3791/64483

Studying the Parkinson’s disease metabolome and exposome in biological samples through different analytical and cheminformatics approaches: a pilot study

Author(s): Begoña Talavera Andújar; Dagny Aurich; Velma T. E. Aho; Randolph R. Singh; Tiejun Cheng; Leonid Zaslavsky; Evan E. Bolton; Brit Mollenhauer; Paul Wilmes; Emma L. Schymanski
Published in: Analytical And Bioanalytical Chemistry (1618-2642) (Springer Science and Business Media LLC), 2022-10 , Vol. 414 , N. 25 , P. 7399-7419, 2022, ISSN 1618-2650
Publisher: Springer Nature
DOI: 10.1007/s00216-022-04207-z

Spatio-functional organization in virocells of small uncultivated archaea from the deep biosphere

Author(s): Indra Banas, Sarah P Esser, Victoria Turzynski, André Soares, Polina Novikova, Patrick May, Cristina Moraru, Mike Hasenberg, Janina Rahlff, Paul Wilmes, Andreas Klingl, Alexander J Probst
Published in: The ISME Journal, Issue 17, 2024, Page(s) 1789-1792, ISSN 1751-7362
Publisher: Nature Publishing Group
DOI: 10.1038/s41396-023-01474-1

Reservoirs of antimicrobial resistance in the context of One Health

Author(s): Milena Despotovic, Laura de Nies, Susheel Bhanu Busi, Paul Wilmes
Published in: Current Opinion in Microbiology, 2023, ISSN 1369-5274
Publisher: Elsevier BV
DOI: 10.1016/j.mib.2023.102291

Diversity and biogeography of the bacterial microbiome in glacier-fed streams

Author(s): Leïla Ezzat, Hannes Peter, Massimo Bourquin, Susheel Bhanu Busi, Grégoire Michoud, Stilianos Fodelianakis, Tyler J. Kohler, Thomas Lamy, Aileen Geers, Paraskevi Pramateftaki, Florian Baier, Ramona Marasco, Daniele Daffonchio, Nicola Deluigi, Paul Wilmes, Michail Styllas, Martina Schön, Matteo Tolosano, Vincent De Staercke, Tom J. Battin
Published in: Nature, Issue 637, 2025, Page(s) 622-630, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-08313-z

Evolution of the murine gut resistome following broad-spectrum antibiotic treatment

Author(s): Laura de Nies, Susheel Bhanu Busi, Mina Tsenkova, Rashi Halder, Elisabeth Letellier, Paul Wilmes
Published in: Nature Communications, Issue 13, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-29919-9

The oral–gut microbiome axis in health and disease

Author(s): Benoit J. Kunath, Charlotte De Rudder, Cedric C. Laczny, Elisabeth Letellier, Paul Wilmes
Published in: Nature Reviews Microbiology, Issue 22, 2024, Page(s) 791-805, ISSN 1740-1526
Publisher: Nature Publishing Group
DOI: 10.1038/s41579-024-01075-5

Mantis: flexible and consensus-driven genome annotation

Author(s): Pedro Queiros, Francesco Delogu, Oskar Hickl, Patrick May, Paul Wilmes
Published in: GigaScience, 2021, ISSN 2047-217X
Publisher: BioMed Central
DOI: 10.1093/gigascience/giab042

Disease Progression, Resilience, and Inflammation Markers During the Coronavirus Disease 2019 Pandemic in Parkinson's Disease.

Author(s): Claire Pauly, Enrico Glaab, Maxime Hansen , Camille Martin-Gallausiaux, Mirko Ledda, Tainá M. Marques, Paul Wilmes, Rejko Krüger, Nico J. Diederich, NCER-PD Consortium
Published in: Movement Disorders, 2022, ISSN 1531-8257
Publisher: Wiley
DOI: 10.1002/mds.29212

Systematic characterization of human gut microbiome-secreted molecules by integrated multi-omics

Author(s): Bianca De Saedeleer, Antoine Malabirade, Javier Ramiro-Garcia, Janine Habier, Jean-Pierre Trezzi, Samantha L. Peters, Annegrät Daujeumont, Rashi Halder, Christian Jäger, Susheel Bhanu Busi, Patrick May, Wolfgang Oertel, Brit Mollenhauer, Cedric C. Laczny, Robert L. Hettich, Paul Wilmes
Published in: ISME Communications, 2021, ISSN 2730-6151
Publisher: Springer Nature
DOI: 10.1038/s43705-021-00078-0

PathoFact: A pipeline for the prediction of virulence factors and antimicrobial resistance genes in metagenomic data

Author(s): Laura de Nies, Sara Lopes, Anna Heintz-Buschart, Cedric Christian Laczny, Patrick May, Paul Wilmes
Published in: bioRxiv, 2020, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2020.03.24.006148

Functional assignment of gut-specific archaeal proteins in the human gut microbiome

Author(s): Polina V. Novikova, Susheel B. Busi, Alexander J. Probst, Patrick May, Paul Wilmes
Published in: bioRxiv, 2022, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.02.01.526569

Metaproteomics in the One Health Framework for Unraveling Microbial Effectors in Microbiomes

Author(s): Robert Heyer, Maximilian Wolf, Dirk Benndorf, Sergio Uzzau, Jana Seifert, Lucia Grenga, Martin Pabst, Heike Schmitt, Bart Mesuere, Tim Van Den Bossche, Sven-Bastiaan Haange, Nico Jehmlich, Mariagrazia Di Luca, Manuel Ferrer, Sergio Serrano-Villar, Jean Armengaud, Helge Bode, Patrick Hellwig, Catherine Robbe Masselot, Renaud Léonard, Paul Wilmes
Published in: ChemRxiv, 2025, ISSN 2573-2293
Publisher: Cambridge Open Engage
DOI: 10.26434/chemrxiv-2024-jg1mq-v2

Integrated multi-omics highlights alterations of gut microbiome functions in prodromal and idiopathic Parkinson’s disease

Author(s): Remy Villette, Júlia Ortís Sunyer, Polina V. Novikova, Velma T. E. Aho, Viacheslav A. Petrov, Oskar Hickl, Susheel Bhanu Busi, Charlotte De Rudder, Benoit Kunath, Anna Heintz-Buschart, Jean-Pierre Trezzi, Rashi Halder, Christian Jäger, Laura A. Lebrun, Annegrät Daujeumont, Sebastian Schade, Annette Janzen, Nico Jehmlich, Martin von Bergen, Cédric C. Laczny, Patrick May, Claudia Trenkwalder, W
Published in: bioRxiv, 2025, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.13.628341

An archaeal compound as a driver of Parkinson’s disease pathogenesis

Author(s): Jean-Pierre Trezzi, Velma T. E. Aho, Christian Jäger, Sebastian Schade, Annette Janzen, Oskar Hickl, Benoit Kunath, Mélanie H. Thomas, Kristopher J. Schmit, Pierre Garcia, Alessia Sciortino, Camille Martin-Gallausiaux, Rashi Halder, Oihane Uriarte Huarte, Tony Heurtaux, Ursula Heins-Marroquin, Gemma Gomez-Giro, Katrin Weidenbach, Léa Delacour, Cedric C. Laczny, Polina V. Novikova, Javier Ramiro
Published in: Research Square, 2022, ISSN 2693-5015
Publisher: Research Square
DOI: 10.21203/rs.3.rs-1827631/v1

UniFuncNet: a flexible network annotation framework

Author(s): Pedro Queirós, Oskar Hickl, Susana Martínez Arbas, Paul Wilmes, Patrick May
Published in: bioRxiv, 2022, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.03.15.484380

Human gut microbiome gene co-expression network reveals a loss in taxonomic and functional diversity in Parkinson′s disease

Author(s): Remy Villette, Polina V Novikova, Cedric Christian Laczny, Brit Mollenhauer, Patrick May, Paul Wilmes
Published in: bioRxiv, 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.18.629142

binny: an automated binning algorithm to recover high-quality genomes from complex metagenomic datasets

Author(s): Oskar Hickl, Pedro Queirós, Paul Wilmes, Patrick May, Anna Heintz-Buschart
Published in: bioRxiv, 2021, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2021.12.22.473795

The response to ketogenic diet in colorectal cancer is mediated by lasting functional alterations of the gut microbiome

Author(s): Mina Tsenkova, Madita Brauer, Marat Kasakin, Susheel Bhanu Busi, Maryse Schmoetten, Anthoula Gaigneaux, Vitaly Pozdeev, Marianne Meyers, Eric Koncina, Diran Herebian, Fabien Rodriguez, Martine Schmitz, Laura de Nies, Ertan Mayatepek, Serge Haan, Carine de Beaufort, Jérôme Graas, Thorsten Cramer, Carole Linster, Paul Wilmes, Elisabeth Letellier
Published in: bioRxiv, 2023, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2023.12.07.570549

Artefactual source of 2-hydroxypyridine

Author(s): Velma T. E. Aho, Jean-Pierre Trezzi, Christian Jäger, Sebastian Schade, Annette Janzen, Oskar Hickl, Benoit Kunath, Mélanie H. Thomas, Kristopher J. Schmit, Pierre Garcia, Alessia Sciortino, Camille Martin-Gallausiaux, Rashi Halder, Oihane Uriarte Huarte, Tony Heurtaux, Ursula Heins-Marroquin, Gemma Gomez-Giro, Katrin Weidenbach, Léa Delacour, Cédric C. Laczny, Polina V. Novikova, Javier Ramir
Published in: Research Square, 2023, ISSN 2693-5015
Publisher: Research Square
DOI: 10.21203/rs.3.rs-1827631/v2

PathoFact 2.0: An Integrative Pipeline for Predicting Antimicrobial Resistance Genes, Virulence Factors, Toxins and Biosynthetic Gene Clusters in Metagenomes

Author(s): Júlia Ortís Sunyer, Luis F. Delgado, Oskar Hickl, Cedric C. Laczny, Patrick May, Paul Wilmes
Published in: bioRxiv, 2024, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.12.09.627531

Dietary fibre deprivation and bacterial curli exposure shift gut microbiome and exacerbate Parkinson’s disease-like pathologies in an alpha-synuclein-overexpressing mouse

Author(s): Kristopher J. Schmit, Alessia Sciortino, Velma T. E. Aho, Pierre Garcia, Beatriz Pardo Rodriguez, Mélanie H. Thomas, Jean-Jacques Gérardy, Rashi Halder, Camille Cialini, Tony Heurtaux, Irati Bastero Acha, Irina Ostahi, Eric C. Martens, Michel Mittelbronn, Manuel Buttini, Paul Wilmes
Published in: bioRxiv, 2022, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2022.03.21.485143

Critical Assessment of MetaProteome Investigation 2 (CAMPI-2): Multi-laboratory assessment of sample processing methods to stabilize fecal microbiome for functional analysis

Author(s): Alessandro Tanca, Kay Schallert, Lucia Grenga, Samantha L. Peters, Marcello Abbondio, Laura De Diego, Maria Antonietta Deledda, Sven-Bastiaan Haange, Guylaine Miotello, Johan S. Sáenz, Maximilian Wolf, Felipe Bastida, Simon Devos, Guillermina Hernandez-Raquet, Jana Seifert, Paul Wilmes, Tim Van Den Bossche, Benoit J. Kunath, Robert Heyer, Nico Jehmlich, Dirk Benndorf, Robert L. Hettich, Jean Arme
Published in: bioRxiv, 2025, ISSN 2692-8205
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2025.01.31.635836

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