Physiological roles of the Ribotoxic Stress Response

Project Information

PHYRIST

Grant agreement ID: 863911

DOI

10.3030/863911

EC signature date 22 January 2020

Start date 1 June 2020

End date 31 December 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 997 678,00

EU contribution

€ 1 997 678,00

Coordinated by

KOBENHAVNS UNIVERSITET
Denmark

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (7)

Ribosomal stress-surveillance: three pathways is a magic number

Author(s): Anna Vind; Aitana Victoria Genzor; Simon Bekker-Jensen
Published in: Nucleic Acids Research, Issue 1, 2020, ISSN 1362-4962
Publisher: Oxford Academic
DOI: 10.1093/nar/gkaa757

PRMT5-mediated regulatory arginine methylation of RIPK3

Author(s): Chauhan C, Martinez-Val A, Niedenthal R, Olsen JV, Kotlyarov A, Bekker-Jensen S, Gaestel M, Menon MB.
Published in: Cell Death and Discovery, 2023, ISSN 2058-7716
Publisher: Nature Publishing Group
DOI: 10.1038/s41420-023-01299-z

Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

Author(s): Snieckute G, Genzor AV, Vind AC, Ryder L, Stoneley M, Chamois S, Dreos R, Nordgaard C, Sass F, Blasius M, López AR, Brynjólfsdóttir SH, Andersen KL, Willis AE, Frankel LB, Poulsen SS, Gatfield D, Gerhart-Hines Z, Clemmensen C, Bekker-Jensen S.
Published in: Cell Metabolism, 2022, ISSN 1550-4131
Publisher: Cell Press
DOI: 10.1016/j.cmet.2022.10.011

Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

Author(s): Silva J, Alkan F, Ramalho S, Snieckute G, Prekovic S, Garcia AK, Hernández-Pérez S, van der Kammen R, Barnum D, Hoekman L, Altelaar M, Zwart W, Suijkerbuijk SJE, Bekker-Jensen S, Faller WJ.
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-32220-4

Regulation of the Golgi Apparatus by p38 and JNK Kinases during Cellular Stress Responses

Author(s): Cathrine Nordgaard, Maxim A X Tollenaere, Ana Martinez Del Val, Dorte B Bekker-Jensen, Melanie Blasius, Jesper V Olsen, Simon Bekker-Jensen
Published in: International Journal of Molecular Sciences, 2021, ISSN 1422-0067
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/ijms22179595

Spatial-proteomics reveals phospho-signaling dynamics at subcellular resolution

Author(s): Ana Martinez-Val, Dorte B Bekker-Jensen, Sophia Steigerwald, Claire Koenig, Ole Østergaard, Adi Mehta, Trung Tran, Krzysztof Sikorski, Estefanía Torres-Vega, Ewa Kwasniewicz, Sólveig Hlín Brynjólfsdóttir, Lisa B Frankel, Rasmus Kjøbsted, Nicolai Krogh, Alicia Lundby, Simon Bekker-Jensen, Fridtjof Lund-Johansen, Jesper V Olsen
Published in: Nature Communications, 2021, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-021-27398-y

ZAKβ is activated by cellular compression and mediates contraction-induced MAP kinase signaling in skeletal muscle

Author(s): Nordgaard C, Vind AC, Stonadge A, Kjøbsted R, Snieckute G, Antas P, Blasius M, Reinert MS, Del Val AM, Bekker-Jensen DB, Haahr P, Miroshnikova YA, Mazouzi A, Falk S, Perrier-Groult E, Tiedje C, Li X, Jakobsen JR, Jørgensen NO, Wojtaszewski JF, Mallein-Gerin F, Andersen JL, Pennisi CP, Clemmensen C, Kassem M, Jafari A, Brummelkamp T, Li VS, Wickström SA, Olsen JV, Blanco G, Bekker-Jensen S.
Published in: EMBO Journal, 2022, ISSN 0261-4189
Publisher: Nature Publishing Group
DOI: 10.15252/embj.2022111650