Tissue-engineering the tumour microenvironment to improve treatment of pancreatic cancer

Project Information

CHIPIN

Grant agreement ID: 864253

DOI

10.3030/864253

EC signature date 17 December 2020

Start date 1 April 2021

End date 31 December 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 000 000,00

EU contribution

€ 2 000 000,00

Coordinated by

LEIBNIZ-INSTITUT FUR POLYMERFORSCHUNG DRESDEN EV
Germany

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (5)

A Tumor Microenvironment Model of Pancreatic Cancer to Elucidate Responses toward Immunotherapy

Author(s): Verena Kast, Ali Nadernezhad, Dagmar Pette, Anastasiia Gabrielyan, Maximilian Fusenig, Kim C. Honselmann, Daniel E. Stange, Carsten Werner, Daniela Loessner
Published in: Advanced Healthcare Materials, Issue Adv. Healthcare Mater.2022,2201907, 2022, Page(s) 2201907 n/a, ISSN 2192-2659
Publisher: World Scientific
DOI: 10.1002/adhm.202201907

Kallikrein-Related Peptidase 6 Is Associated with the Tumour Microenvironment of Pancreatic Ductal Adenocarcinoma

Author(s): Juliana B. Candido, Oscar Maiques, Melanie Boxberg, Verena Kast, Eleonora Peerani, Elena Tomás-Bort, Wilko Weichert, Amiram Sananes, Niv Papo, Viktor Magdolen, Victoria Sanz-Moreno, Daniela Loessner
Published in: Cancers, Issue 13/16, 2021, Page(s) 3969, ISSN 2072-6694
Publisher: Multidisciplinary Digital Publishing Institute (MDPI)
DOI: 10.3390/cancers13163969

Biomaterial-based platforms for tumour tissue engineering

Author(s): Rodrigo Curvello, Verena Kast, Paloma Ordóñez-Morán, Alvaro Mata, Daniela Loessner
Published in: Nature Reviews Materials, Issue 8, 2023, Page(s) 314–330 (2023), ISSN 2058-8437
Publisher: Springer Nature
DOI: 10.1038/s41578-023-00535-3

Recreating metabolic interactions of the tumour microenvironment

Author(s): Rodrigo Curvello, Nikolaus Berndt, Sandra Hauser, Daniela Loessner
Published in: Trends in Endocrinology & Metabolism, Issue 35, 2024, Page(s) 518-532, ISSN 1043-2760
Publisher: Elsevier BV
DOI: 10.1016/j.tem.2023.12.005

A biomaterial-based platform of pancreatic cancer reveals kallikrein-related peptidase 6 (KLK6) as a mediator of neutrophil recruitment and immunosuppression

Author(s): Verena J. Kast, Sandra Hauser, Ali Nadernezhad, Dagmar Pette, Manfred F. Maitz, Andreas Petzold, Andreas Dahl, Michael Seifert, Katja Eubler, Artur Mayerhofer, Jens Pietzsch, Franziska Baenke, Daniel E. Stange, Carsten Werner, Daniela Loessner
Published in: Biomaterials, Issue 324, 2025, Page(s) 123456, ISSN 0142-9612
Publisher: Pergamon Press Ltd.
DOI: 10.1016/j.biomaterials.2025.123456

Non-peer reviewed articles (1)

Tailoring metabolic activity assays for tumour-engineered 3D models

Author(s): Julien Clegg, Rodrigo Curvello, Anastasiia Gabrielyan, Daniel Croagh, Sandra Hauser, Daniela Loessner
Published in: Biomaterials Advances, Issue 167, 2024, Page(s) 214116, ISSN 2772-9508
Publisher: Elsevier BV
DOI: 10.1016/j.bioadv.2024.214116