Physiologically Crowded Artificial Cells for Relevant Drug Screens

Project Information

PArtCell

Grant agreement ID: 864528

DOI

10.3030/864528

Project closed

EC signature date 3 February 2020

Start date 1 March 2020

End date 31 August 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 994 956,00

EU contribution

€ 1 994 956,00

Coordinated by

UNIVERSITEIT UTRECHT
Netherlands

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Macromolecular Crowding, Phase Separation, and Homeostasis in the Orchestration of Bacterial Cellular Functions

Author(s): Begoña Monterroso, William Margolin, Arnold J. Boersma, Germán Rivas, Bert Poolman, Silvia Zorrilla
Published in: Chemical Reviews, Issue 124, 2024, Page(s) 1899-1949, ISSN 0009-2665
Publisher: American Chemical Society
DOI: 10.1021/acs.chemrev.3c00622

Cell wall damage increases macromolecular crowding effects in the Escherichia coli cytoplasm

Author(s): Theodoros Pittas, Weiyan Zuo, Arnold J. Boersma
Published in: iScience, Issue 26, 2025, Page(s) 106367, ISSN 2589-0042
Publisher: Cell Press
DOI: 10.1016/j.isci.2023.106367

Probing Electrostatic and Hydrophobic Associative Interactions in Cells

Author(s): Weiyan Zuo, Meng-Ruo Huang, Fabian Schmitz, Arnold J. Boersma
Published in: The Journal of Physical Chemistry B, Issue 128, 2024, Page(s) 10861-10869, ISSN 1520-6106
Publisher: American Chemical Society
DOI: 10.1021/acs.jpcb.4c05990

Liposome-Encapsulated <i>Escherichia coli</i> Lysates to Reconstitute Intracellular Macromolecular Crowding Effects

Author(s): Milara S. Kalacheva, Nuno R. da Silva, Arnold J. Boersma
Published in: ACS Synthetic Biology, Issue 14, 2025, Page(s) 901-908, ISSN 2161-5063
Publisher: American Chemical Society
DOI: 10.1021/acssynbio.4c00824

High Macromolecular Crowding in Liposomes from Microfluidics

Author(s): Luis P. B. Guerzoni; André V. C. de Goes; Milara Kalacheva; Jakub Haduła; Matthias Mork; Laura De Laporte; Arnold J. Boersma
Published in: Advanced Science, Issue 1, 2022, ISSN 2198-3844
Publisher: Wiley-VCH
DOI: 10.1002/advs.202201169

A FRET-based method for monitoring structural transitions in protein self-organization

Author(s): Qi Wan, Sara N. Mouton, Liesbeth M. Veenhoff, Arnold J. Boersma
Published in: Cell Reports Methods, 2022, ISSN 2667-2375
Publisher: Elsevier
DOI: 10.1016/j.crmeth.2022.100184