Project description
Rational design of sustainable metal catalysts could have far-reaching effects
Most metal-catalysed processes rely on what chemists call 'polar reactivity', where reactions involve the transfer or sharing of two electrons at a time. In the relatively new field of metalloradical catalysis, however, reactions occur with the transfer or sharing of only one electron at a time. While catalysing two-electron polar reactions conventionally relies on rare and expensive metal ions, one-electron metalloradical reactions are accomplished sustainably with catalysts based on abundant and inexpensive transition metals, with applications in fine chemicals, medicine and materials science. The EU-funded MetalloRadiCat project is enhancing understanding of metalloradical reactivity and its associated principles to further rational design of metalloradical catalysts and catalytic processes, particularly with respect to the emerging area of remote functionalisations. The team is focused on novel molecules and functionalities in the context of methane production and activation.
Objective
Over the past decades, metal catalysis has had a tremendous impact in chemistry, its adjacent disciplines and society overall, having gained an omnipresence in academic and industrial research worldwide. Numerous previously unthinkable transformations can nowadays be achieved in a selective and relatively mild manner owing to the metals' unique ability to trigger bond-making and breaking via pathways and principles that are inaccessible to metal-free processes. In this context, the global community has focused primarily on closed-shell, two electron processes for synthetic transformations. By comparison, the field of metalloradical catalysis has seen much less development, although metalloradicals are nature's preferred species to tame radical reactivities under non-precious metal-catalysis in numerous metalloenzymes. This is likely due to our currently limited understanding of metalloradical reactivity and its associated principles, and as such also limited ability to rationally design metalloradical catalysts and catalytic processes. A multidisciplinary approach, which capitalizes on the principles and insights of organic, organometallic and biological processes, will likely be key to meet the next frontier in this promising field. The objective of this proposal is to combine the tools of mechanistic, computational and synthetic organic/organometallic chemistry to explore catalysis with metalloradicals in synthesis, materials research and enzymatic processes. The proposed program will investigate some of the most pertinent questions in relation to the emerging area of remote functionalizations for the selective synthetic access to tailored molecules, olefin migrations and manipulations, and naturally occurring (enzymatic) metalloradical-catalyzed processes in the context of methane production and activation.
Fields of science (EuroSciVoc)
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
CORDIS classifies projects with EuroSciVoc, a multilingual taxonomy of fields of science, through a semi-automatic process based on NLP techniques. See: The European Science Vocabulary.
- natural sciences chemical sciences catalysis
- natural sciences chemical sciences organic chemistry aliphatic compounds
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Keywords
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Project’s keywords as indicated by the project coordinator. Not to be confused with the EuroSciVoc taxonomy (Fields of science)
Programme(s)
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
Multi-annual funding programmes that define the EU’s priorities for research and innovation.
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H2020-EU.1.1. - EXCELLENT SCIENCE - European Research Council (ERC)
MAIN PROGRAMME
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Topic(s)
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Calls for proposals are divided into topics. A topic defines a specific subject or area for which applicants can submit proposals. The description of a topic comprises its specific scope and the expected impact of the funded project.
Funding Scheme
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
Funding scheme (or “Type of Action”) inside a programme with common features. It specifies: the scope of what is funded; the reimbursement rate; specific evaluation criteria to qualify for funding; and the use of simplified forms of costs like lump sums.
ERC-COG - Consolidator Grant
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Call for proposal
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
Procedure for inviting applicants to submit project proposals, with the aim of receiving EU funding.
(opens in new window) ERC-2019-COG
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Net EU financial contribution. The sum of money that the participant receives, deducted by the EU contribution to its linked third party. It considers the distribution of the EU financial contribution between direct beneficiaries of the project and other types of participants, like third-party participants.
52062 Aachen
Germany
The total costs incurred by this organisation to participate in the project, including direct and indirect costs. This amount is a subset of the overall project budget.