Molecular pathology of anti-viral T cell responses in the central nervous system

Project Information

PATHOCODE

Grant agreement ID: 865026

DOI 10.3030/865026

EC signature date 16 March 2020

Start date 1 August 2020

End date 31 July 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 954,00

EU contribution € 1 999 954,00

Coordinated by

UNIVERSITE DE GENEVE
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (6)

Neuronal metabotropic glutamate receptor 8 protects against neurodegeneration in CNS inflammation

Author(s): Woo MS, Ufer F, Rothammer N, Di Liberto G, Binkle L, Haferkamp U, Sonner JK, Engler JB, Hornig S, Bauer S, Wagner I, Egervari K, Raber J, Duvoisin RM, Pless O, Merkler D, Friese MA.
Published in: Journal of Experimental Medicine, 2021, ISSN 1540-9538
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20201290

Formation and immunomodulatory function of meningeal B-cell aggregates in progressive CNS autoimmunity

Author(s): Meike Mitsdoerffer; Giovanni Di Liberto; Sarah Dötsch; Christopher Sie; Ingrid Wagner; Monika Pfaller; Mario Kreutzfeldt; Simon Fräßle; Lilian Aly; Benjamin Knier; Dirk H Busch; Doron Merkler; Thomas Korn
Published in: Brain (2021), Issue 1, 2021, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awab093

G9a dictates neuronal vulnerability to inflammatory stress via transcriptional control of ferroptosis

Author(s): Rothammer N, Woo MS, Bauer S, Binkle-Ladisch L, Di Liberto G, Egervari K, Wagner I, Haferkamp U, Pless O, Merkler D, Engler JB, Friese MA
Published in: Science Advances, 2022, ISSN 2375-2548
Publisher: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abm5500

Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation

Author(s): Jafari M, Schumacher AM, Snaidero N, Ullrich Gavilanes EM, Neziraj T, Kocsis-Jutka V, Engels D, Jürgens T, Wagner I, Weidinger JDF, Schmidt SS, Beltrán E, Hagan N, Woodworth L, Ofengeim D, Gans J, Wolf F, Kreutzfeldt M, Portugues R, Merkler D, Misgeld T, Kerschensteiner M.
Published in: Nature Neuroscience, 2021, ISSN 1097-6256
Publisher: Nature Publishing Group
DOI: 10.1038/s41593-020-00780-7

Persistent RNA virus infection is short-lived at the single-cell level but leaves transcriptomic footprints

Author(s): Peter Reuther; Katrin Martin; Mario Kreutzfeldt; Matias Ciancaglini; Florian Geier; Diego Calabrese; Doron Merkler; Daniel D. Pinschewer
Published in: Journal of Experimental Medicine, Issue 1, 2021, ISSN 0022-1007
Publisher: Rockefeller University Press
DOI: 10.1084/jem.20210408

Neurodegenerative phagocytes mediate synaptic stripping in Neuro-HIV

Author(s): Giovanni Di Liberto, Kristof Egervari, Mario Kreutzfeldt, Christian M Schürch, Ekkehard Hewer, Ingrid Wagner, Renaud Du Pasquier, Doron Merkler
Published in: Brain, Issue 145, 2022, Page(s) 2730-2741, ISSN 0006-8950
Publisher: Oxford University Press
DOI: 10.1093/brain/awac102