Novel biomarkers of energy metabolism in depression
Emerging evidence indicates that Major depressive disorder (MDD) is associated with reduced mitochondrial energy production and impaired oxygen homeostasis along with elevated levels of inflammatory activity and oxidative stress. The key objective of the EU-funded MitO2Health project is to investigate the physiological mechanisms underlying MDD. Scientists will assess the clinical and biological status of patients receiving cognitive behavioural therapy (CBT) in comparison with untreated individuals as well as healthy controls. The study will help to identify biomarkers related to individual therapy response and relapse and, thereby, it will contribute to develop novel biologically founded diagnostic criteria for MDD along with paving the way for innovative treatment concepts.
Fields of science
Call for proposal
See other projects for this call