Chromatin readout: Dissecting the protein-chromatin interaction code in living cells

Project Information

ChromatinLEGO

Grant agreement ID: 865094

DOI 10.3030/865094

EC signature date 22 January 2020

Start date 1 September 2020

End date 31 August 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 1 999 375,00

EU contribution € 1 999 375,00

Coordinated by

UNIVERSITEIT UTRECHT
Netherlands

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (3)

Dissecting the roles of MBD2 isoforms and domains in regulating NuRD complex function during cellular differentiation

Author(s): Nina Schmolka, Ino D. Karemaker, Richard Cardoso da Silva, Davide C. Recchia, Vincent Spegg, Jahnavi Bhaskaran, Michael Teske, Nathalie P. de Wagenaar, Matthias Altmeyer, Tuncay Baubec
Published in: Nature Communications, Issue 14, 2023, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-39551-w

High-affinity chromodomains engineered for improved detection of histone methylation and enhanced CRISPR-based gene repression

Author(s): G. Veggiani, Rodrigo Villaseñor, G. D. Martyn, J. Q. Tang, M. W. Krone, J. Gu, C. Chen, M. L. Waters, K. H. Pearce, Tuncay Baubec & S. S. Sidhu
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-34269-7

DNA sequence and chromatin modifiers cooperate to confer epigenetic bistability at imprinting control regions

Author(s): Stefan Butz, Nina Schmolka, Ino D Karemaker, Rodrigo Villaseñor, Isabel Schwarz, Silvia Domcke, Esther C H Uijttewaal, Julian Jude, Florian Lienert, Arnaud R Krebs, Nathalie P de Wagenaar, Xue Bao, Johannes Zuber, Ulrich Elling, Dirk Schübeler, Tuncay Baubec
Published in: Nature Genetics, 2022, ISSN 1061-4036
Publisher: Nature Publishing Group
DOI: 10.1038/s41588-022-01210-z

Non-peer reviewed articles (1)

Regulatory mechanisms governing chromatin organization and function

Author(s): Rodrigo Villaseñor, Tuncay Baubec
Published in: Current Opinion in Cell Biology, 2021, ISSN 0955-0674
Publisher: Elsevier BV
DOI: 10.1016/j.ceb.2020.10.015

Other (2)

Probing DNA damage sites reveals context-dependent and novel DNA damage response factors

Author(s): Richard Cardoso da Silva, Davide C. Recchia, Vincent Portegijs, Maria Cristina Trueba Sanchez, Kelly E. Stecker, Sander van den Heuvel, Tuncay Baubec
Published in: biorXiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.23.619792

SETD2 promotes PAF1C interactions with the elongating RNA Pol II and is required for neuronal differentiation

Author(s): Christina Ambrosi, Ramon Pfaendler, Stefan Butz, Davide Recchia, Xue Bao, Nina Schmolka, Tuncay Baubec
Published in: biorXiv, 2024
Publisher: Cold Spring Harbor Laboratory
DOI: 10.1101/2024.10.23.619798