Artificial Enzyme Modules as Tools in a Tailor-made Biosynthesis

Project Information

ABIONYS

Grant agreement ID: 865885

DOI

10.3030/865885

EC signature date 18 February 2020

Start date 1 November 2020

End date 31 October 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 1 995 707,00

EU contribution

€ 1 995 707,00

Coordinated by

HELSINGIN YLIOPISTO
Finland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (10)

Multienzymatic Synthesis of γ-Lactam Building Blocks from Unsaturated Esters and Hydroxylamine

Author(s): Jäger, Christina; Nieger, Martin; Rissanen, Kari; Deska, Jan
Published in: European Journal of Organic Chemistry, Issue 07.08.2023, 2023, Page(s) 7, ISSN 1099-0690
Publisher: Wiley-VCH GmbH
DOI: 10.1002/ejoc.202300288

Choline Oxidase and Choline Ionic Liquids in Biocatalytic Heme Peroxidase Cascades

Author(s): Marleen Hallamaa, Janne M. Naapuri, Rafaela A. L. Silva, Andreia A. Rosatella, Jan Deska
Published in: ChemCatChem, Issue 17, 2025, ISSN 1867-3880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/cctc.202401216

Peroxidase-induced C–N bond formation via nitroso ene and Diels–Alder reactions

Author(s): Jäger, Christina; Gregori, Berhard J.; Aho, J. A. S.; Hallamaa, M.; Deska, J.
Published in: Green Chemistry, 2023, ISSN 1463-9270
Publisher: Royal Society of Chemistry
DOI: 10.1039/d2gc04827b

Guanidium Unmasked: Repurposing Common Amide Coupling Reagents for the Synthesis of Pentasubstituted Guanidine Bases

Author(s): Juhana A. S. Aho, Jere K. Mannisto, Saku P. M. Mattila, Marleen Hallamaa, Jan Deska
Published in: The Journal of Organic Chemistry, Issue 90, 2025, Page(s) 2636-2643, ISSN 0022-3263
Publisher: American Chemical Society
DOI: 10.1021/acs.joc.4c02645

An Artificial In Vitro Metabolism to Angiopterlactone B Inspired by Traditional Retrosynthesis

Author(s): Kiefer, Alexander K.; Liu, Yu-Chang; Gummerer, Rebecca; Jäger, Christina; Deska, Jan
Published in: Angewandte Chemie International Edition, 2023, ISSN 1521-3757
Publisher: Wiley-VCH GmbH
DOI: 10.1002/anie.202301178

Enzymatic Bromocyclization of α- and γ-Allenols by Chloroperoxidase from Curvularia inaequalis

Author(s): Naapuri, Janne M.; Wagner, Philip K.; Hollmann, Frank; Deska, Jan
Published in: ChemistryOpen, 2022, Page(s) 6, ISSN 2191-1363
Publisher: Wiley-VCH GmbH
DOI: 10.1002/open.202100236

Aerobic C−N Bond Formation through Enzymatic Nitroso-Ene-Type Reactions

Author(s): Jäger, Christina; Haase, Mona; Koschorreck, Katja; Urlacher, Vlada B.; Deska, Jan
Published in: Angewandte Chemie International Edition, 2023, Page(s) 7, ISSN 1521-3757
Publisher: Wiley-VCH GmbH
DOI: 10.1002/anie.202213671

Coding Synthetic Chemistry Strategies for Furan Valorization into Bacterial Designer Cells

Author(s): Liu, Yu-Chang; Wu, Zhong-Liu; Deska, Jan
Published in: ChemSusChem, 2023, Page(s) e202201790, ISSN 1864-564X
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cssc.202201790

Fully Biocatalytic Rearrangement of Furans to Spirolactones

Author(s): Liu, Yu-Chang; Rolfes, J. D.; Björklund, Joel; Deska, Jan
Published in: ACS Catalysis, 2023, Page(s) 7, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.3c00132

Cascade Catalysis Through Bifunctional Lipase Metal Biohybrids for the Synthesis of Enantioenriched O-Heterocycles from Allenes

Author(s): Naapuri; Janne M.; Losada-Garcia, Noelia; Rothemann, R. Alexander; Carmona Pichardo, Manuel; Prechtl, Martin H. G.; Palomo, Jose M.; Deska, Jan
Published in: ChemCatChem, 2022, ISSN 1867-3899
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cctc.202200362

Other (2)

Asymmetric Ring Contraction of 2-Hydroxypyranones by Borrowing Hydrogen Biocatalysis

Author(s): Yuchang Liu, J. D. Rolfes, Jan Deska
Published in: ChemRxiv, 2025
Publisher: Cambridge University Press
DOI: 10.26434/chemrxiv-2025-9hpvb

A Streamlined Chemoenzymatic One-Pot Process for the Enantioselective Total Synthesis of Tenuipesone A/B

Author(s): Marleen Hallamaa, Adam O'Connell, Joel Björklund, Yu-Chang Liu, Jan Deska
Published in: ChemRxiv, 2025
Publisher: Cambridge University Press
DOI: 10.26434/chemrxiv-2025-rbj31