Cooperative Intelligence in Swarms of Enzyme-Nanobots

Información del proyecto

i-NANOSWARMS

Identificador del acuerdo de subvención: 866348

DOI

10.3030/866348

Fecha de la firma de la CE 28 Abril 2020

Fecha de inicio 1 Octubre 2020

Fecha de finalización 30 Septiembre 2026

Financiado con arreglo a

• EXCELLENT SCIENCE - European Research Council (ERC)

Coste total

€ 1 999 819,00

Aportación de la UE

€ 1 999 819,00

Coordinado por

FUNDACIO INSTITUT DE BIOENGINYERIA DE CATALUNYA
Spain

CORDIS proporciona enlaces a los documentos públicos y las publicaciones de los proyectos de los programas marco HORIZONTE.

Los enlaces a los documentos y las publicaciones de los proyectos del Séptimo Programa Marco, así como los enlaces a algunos tipos de resultados específicos, como conjuntos de datos y «software», se obtienen dinámicamente de OpenAIRE .

Publicaciones

Peer reviewed articles (26)

Urease-powered nanomotor containing STING agonist for bladder cancer immunotherapy

Autores: Hyunsik Choi, Seung-hwan Jeong, Cristina Simó, Anna Bakenecker, Jordi Liop, Hye Sun Lee, Tae Yeon Kim, Cheol Kwak, Gou Young Koh, Samuel Sánchez, Sei Kwang Hahn
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-54293-z

Collective buoyancy-driven dynamics in swarming enzymatic nanomotors

Autores: Shuqin Chen, Xander Peetroons, Anna C. Bakenecker, Florencia Lezcano, Igor S. Aranson, Samuel Sánchez
Publicado en: Nature Communications, Edición 15, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-024-53664-w

Multicolor Super-Resolution Microscopy of Protein Corona on Single Nanoparticles

Autores: Yuyang Wang; Paul E. D. Soto Rodriguez; Laura Woythe; Samuel Sánchez; Josep Samitier; Peter Zijlstra; Lorenzo Albertazzi
Publicado en: Acs Applied Materials & Interfaces, 2022, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.2c06975

Enzyme-powered micro- and nano-motors: key parameters for an application-oriented design

Autores: Xavier Arqué; Tania Patiño; Samuel Sánchez
Publicado en: Chemical Science, 2022, ISSN 1478-6524
Editor: Royal Society of Chemistry
DOI: 10.1039/d2sc90162e

Catalase-Powered Nanobots for Overcoming the Mucus Barrier

Autores: Meritxell Serra-Casablancas, Valerio Di Carlo, David Esporrín-Ubieto, Carles Prado-Morales, Anna C. Bakenecker, Samuel Sánchez
Publicado en: ACS Nano, Edición 18, 2024, Página(s) 16701-16714, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.4c01760

Inferring non-equilibrium interactions from tracer response near confined active Janus particles

Autores: Jaideep Katuri, William E Uspal, Mihail N. Popescu, Samuel Sánchez
Publicado en: Science Advances, 2021, ISSN 2375-2548
Editor: American Association for the Advancement of Science
DOI: 10.1126/sciadv.abd0719

Micro- and Nanomotors: Engineered Tools for Targeted and Efficient Biomedicine

Autores: Noelia Ruiz-González, David Esporrín-Ubieto, Il-Doo Kim, Joseph Wang, Samuel Sánchez
Publicado en: ACS Nano, Edición 19, 2025, Página(s) 8411-8432, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.4c12726

Radionuclide therapy based on accumulated urease-powered nanobots in the bladder tumor of an orthotopic murine model

Autores: Cristina Simó, Meritxell Serra-Casablancas, Ana Hortelao, Valerio Di Carlo, Sandra Guallar-Garrido, Sandra Plaza-Garcia, Pedro Ramos-Cabrer, Balbino Yagüe, Laura Aguado, Lídia Bardía, Sebastien Tosi, Vanessa Gómez-Vallejo, Abraham Martín, Tania Patiño, Esther Julián, Julien Colombelli, Jordi Llop, Samuel Sanchez
Publicado en: Nature nanotechnology, 2024, ISSN 1748-3395
Editor: Springer nature
DOI: 10.21203/rs.3.rs-2704683/v1

Biohybrid soft robots with self-stimulating skeletons

Autores: Maria Guix, Rafael Mestre, Tania Patiño, Marco de Corato, Judith Fuentes, Giulia Zarpellon, Samuel Sánchez
Publicado en: Science Robotics, 2021, ISSN 2470-9476
Editor: American Association for the Advancement of Science
DOI: 10.1126/scirobotics.abe7577

Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder

Autores: Ana C. Hortelão; Cristina Simó; Maria Guix; Sandra Guallar-Garrido; Esther Julián; Diana Vilela; Luka Rejc; Pedro Ramos-Cabrer; Unai Cossío; Vanessa Gómez-Vallejo; Tania Patiño; Jordi Llop; Samuel Sanchez
Publicado en: Science Robotics, 2021, ISSN 2470-9476
Editor: American Association for the Advancement of Science
DOI: 10.1126/scirobotics.abd2823

Autonomous Treatment of Bacterial Infections in Vivo Using Antimicrobial Micro- and Nanomotors

Autores: Xavier Arqué, Marcelo D. T. Torres, Tania Patiño, Andreia Boaro, Samuel Sánchez*, Cesar de la Fuente-Nunez*
Publicado en: ACS Nano, 2022, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.1c11013

Swarms of Enzyme‐Powered Nanomotors Enhance the Diffusion of Macromolecules in Viscous Media

Autores: Noelia Ruiz‐González, David Esporrín‐Ubieto, Ana C. Hortelao, Juan C. Fraire, Anna C. Bakenecker, Marta Guri‐Canals, Ramón Cugat, José María Carrillo, Montserrat Garcia‐Batlletbó, Patricia Laiz, Tania Patiño, Samuel Sánchez
Publicado en: Small, Edición 20, 2024, ISSN 1613-6810
Editor: Wiley - V C H Verlag GmbbH & Co.
DOI: 10.1002/smll.202309387

Urease-powered nanobots for radionuclide bladder cancer therapy

Autores: Cristina Simó, Meritxell Serra-Casablancas, Ana C. Hortelao, Valerio Di Carlo, Sandra Guallar-Garrido, Sandra Plaza-García, Rosa Maria Rabanal, Pedro Ramos-Cabrer, Balbino Yagüe, Laura Aguado, Lídia Bardia, Sébastien Tosi, Vanessa Gómez-Vallejo, Abraham Martín, Tania Patiño, Esther Julián, Julien Colombelli, Jordi Llop, Samuel Sánchez
Publicado en: Nature Nanotechnology, Edición 19, 2024, Página(s) 554-564, ISSN 1748-3387
Editor: Nature Publishing Group
DOI: 10.1038/s41565-023-01577-y

Nanorods Based on Mesoporous Silica Containing Iron Oxide Nanoparticles as Catalytic Nanomotors: Study of Motion Dynamics

Autores: Rafael Mestre; Núria Cadefau; Ana C. Hortelão; Jan Grzelak; Martí Gich; Anna Roig; Samuel Sanchez
Publicado en: ChemNanoMat, 2020, ISSN 2199-692X
Editor: Wiley
DOI: 10.1002/cnma.202000557

Enzyme-Powered Porous Micromotors Built from a Hierarchical Micro- and Mesoporous UiO-Type Metal-Organic Framework.

Autores: Yunhui Yang; Xavier Arqué; Tania Patiño; Vincent Guillerm; Pascal-Raphael Blersch; Javier Pérez-Carvajal; Inhar Imaz; Daniel Maspoch; Samuel Sanchez
Publicado en: Journal of the American Chemical Society, 2020, ISSN 0002-7863
Editor: American Chemical Society
DOI: 10.1021/jacs.0c11061

Enzyme Purification Improves the Enzyme Loading, Self-Propulsion, and Endurance Performance of Micromotors

Autores: Morgane Valles; Sílvia Pujals; Lorenzo Albertazzi; Samuel Sánchez
Publicado en: ACS Nano, 2022, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.1c10520

Improved Performance of Biohybrid Muscle-Based Bio-Bots Doped with Piezoelectric Boron Nitride Nanotubes

Autores: Mestre, R; Fuentes, J; Lefaix, L; Wang, JJ; Guix, M; Murillo, G; Bashir, R; Sanchez, S
Publicado en: Advanced Materials Technologies., 2023, ISSN 2365-709X
Editor: Wiley-VCH GmbH, Weinheim
DOI: 10.1002/admt.202200505

Biohybrid robotics: From the nanoscale to the macroscale

Autores: Rafael Mestre; Tania Patiño; Samuel Sanchez; Samuel Sanchez
Publicado en: WIREs Nanomedicine and Nanobiotechnology, 2021, ISSN 1939-0041
Editor: John Wiley & Sons Inc.
DOI: 10.1002/wnan.1703

Natural Hydrogels Support Kidney Organoid Generation and Promote In Vitro Angiogenesis

Autores: Elena Garreta, Daniel Moya‐Rull, Andrés Marco, Gaia Amato, Asier Ullate‐Agote, Carolina Tarantino, Maria Gallo, David Esporrín‐Ubieto, Alberto Centeno, Amaia Vilas‐Zornoza, Rafael Mestre, María Kalil, Izar Gorroñogoitia, Ane Miren Zaldua, Samuel Sanchez, Laura Izquierdo Reyes, María Eugenia Fernández‐Santos, Felipe Prosper, Nuria Montserrat
Publicado en: Advanced Materials, Edición 36, 2024, ISSN 0935-9648
Editor: United Nations Industrial Developement Organization
DOI: 10.1002/adma.202400306

Convective Dynamics of Swarming Enzymatic Nanomotors

Autores: Samuel Sánchez, Shuqin Chen, Xander Peetroons, Anna Bakenecker, Florencia Lezcano, Igor Aronson
Publicado en: Nature communications, 2024, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.21203/rs.3.rs-3999734/v1

Guided accumulation of active particles by topological design of a second-order skin effect

Autores: Lucas S. Palacios; Serguei Tchoumakov; Maria Guix; Ignacio Pagonabarraga; Ignacio Pagonabarraga; Samuel Sanchez; Adolfo G. Grushin
Publicado en: Nature Communications, 2021, ISSN 2041-1723
Editor: Nature Publishing Group
DOI: 10.1038/s41467-021-24948-2

Drug-Free Enzyme-Based Bactericidal Nanomotors against Pathogenic Bacteria.

Autores: Diana Vilela; Núria Blanco-Cabra; Ander Eguskiza; Ana C. Hortelão; Eduard Torrents; Samuel Sanchez
Publicado en: ACS Applied Materials & Interfaces, 2021, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.1c00986

Light-Triggered Mechanical Disruption of Extracellular Barriers by Swarms of Enzyme-Powered Nanomotors for Enhanced Delivery

Autores: Juan C. Fraire, Maria Guix, Ana C. Hortelao, Noelia Ruiz-González, Anna C. Bakenecker, Pouria Ramezani, Charlotte Hinnekens, Félix Sauvage, Stefaan C. De Smedt, Kevin Braeckmans, Samuel Sánchez
Publicado en: ACS nano, 2023, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.2c09380

Swarms of Enzymatic Nanobots for Efficient Gene Delivery

Autores: Juan C. Fraire, Carles Prado-Morales, Ana Aldaz Sagredo, Ainhoa G. Caelles, Florencia Lezcano, Xander Peetroons, Anna C. Bakenecker, Valerio Di Carlo, Samuel Sánchez
Publicado en: ACS Applied Materials & Interfaces, Edición 16, 2024, Página(s) 47192-47205, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.4c08770

Boosting the Efficiency of Photoactive Rod-Shaped Nanomotors via Magnetic Field-Induced Charge Separation

Autores: Rebeca Ferrer Campos, Anna C. Bakenecker, Yufen Chen, Maria Chiara Spadaro, Juan Fraire, Jordi Arbiol, Samuel Sánchez, Katherine Villa
Publicado en: ACS Applied Materials & Interfaces, Edición 16, 2024, Página(s) 30077-30087, ISSN 1944-8244
Editor: American Chemical Society
DOI: 10.1021/acsami.4c03905

Real-Time Optical Tracking of Protein Corona Formation on Single Nanoparticles in Serum

Autores: Mathias Dolci, Yuyang Wang, Sjoerd W. Nooteboom, Paul Eduardo David Soto Rodriguez, Samuel Sánchez, Lorenzo Albertazzi, Peter Zijlstra
Publicado en: ACS Nano, Edición 17, 2023, Página(s) 20167-20178, ISSN 1936-0851
Editor: American Chemical Society
DOI: 10.1021/acsnano.3c05872

Other (1)

Protein corona formation around biocatalytic nanomotors unveiled by STORM

Autores: Tania Patino, Joaquin Llacer-Wintle, Silvia Pujals, Lorenzo Albertazzi, Samuel Sánchez
Publicado en: 2023
Editor: American Chemical Society (ACS)
DOI: 10.26434/chemrxiv-2021-rhtps