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Fast optoacoustic mesoscopy, using the skin as a window for therapeutic monitoring of local and systemic disease.

Deliverables

Public promotion leaflet and F-RSOM postcard

Public awareness documents containing EU Horizon 2020 WINTHER and partner logos and impressive images generated by FRSOM and explanation of WINTHER goals achievements and impact

Project web site

Creation of a project logo and web site comprising a public domain and a password-protected area. The public area will serve as reference point for the public and industry (project description, accomplishments, activities), while the internal use-only area will provide secure data and information exchange for the consortium partners (containing the management and quality manual, and a data and document repository and description of WINTHER goals).

Publications

Enabling precision monitoring of psoriasis treatment by optoacoustic mesoscopy

Author(s): Hindelang, B., Nau, T., Englert, L., Berezhnoi, A., Lauffer, F., Darsow, U., Biedermann, T., Eyerich, K., Aguirre, J., and Ntziachristos, V.
Published in: Science Translational Medicine, 2022, ISSN 1946-6234
Publisher: American Association for the Advancement of Science
DOI: 10.1126/scitranslmed.abm8059

Raster-scanning optoacoustic mesoscopy biomarkers for atopic dermatitis skin lesions

Author(s): Nau, T., Schönmann, C., Hindelang, B., Riobo, L., Doll, A., Schneider, S., Englert, L., He, H., Biedermann, T., Darsow, U., Lauffer, F., Ntziachristos, V., and Aguirre, J.
Published in: Photoacoustics, 2023, ISSN 2213-5979
Publisher: Elsevier GmbH
DOI: 10.1016/j.pacs.2023.100513

Optoacoustic imaging in endocrinology and metabolism

Author(s): Karlas, A., Pleitez, M.A., Aguirre, J., and Ntziachristos, N.
Published in: Nature Reviews Endocrinology, Issue 17(6), 2021, Page(s) 323-335, ISSN 1759-5037
Publisher: Springer Nature
DOI: 10.1038/s41574-021-00482-5

Opening a window to skin biomarkers for diabetes stage with optoacoustic mesoscopy

Author(s): Hailong He; Nikolina-Alexia Fasoula; Angelos Karlas; Murad Omar; Juan Aguirre; Jessica Lutz; Michael Kallmayer; Martin Füchtenbusch; Hans-Henning Eckstein; Annette Ziegler; Vasilis Ntziachristos
Published in: Light: Science & Applications, Vol 12, Iss 1, Pp 1-15 (2023), Issue 4, 2023, ISSN 2047-7538
Publisher: Nature
DOI: 10.1038/s41377-023-01275-3

Fast raster-scan optoacoustic mesoscopy enables assessment of human melanoma microvasculature in vivo

Author(s): He, H., Schönmann, C., Schwarz, M., Hindelang, B., Bereznhoi, A., Steimle-Grauer, A., Darsow, U., Aguirre, J., and Ntziachristos, V.
Published in: Nature Communications, 2022, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-022-30471-9

Fast 3D Optoacoustic Mesoscopy of Neuromelanin Through Entire Human Midbrain Organoids at Single-Cell Resolution

Author(s): Englert, L., Lacalle-Aurioles, M., Mohamed, N.-V., Lépine, P., Mathur, M., Ntziachristos, V., Durcan T.M. and Aguirre, J.
Published in: Laser and Photonics Reviews, 2023, ISSN 1863-8880
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/lpor.202300443

Enabling the autofocus approach for parameter optimization in planar measurement geometry clinical optoacoustic imaging

Author(s): Englert, L., Riobo, L., Schönmann, C., Ntziachristos, V., and Aguirre, J.
Published in: Journal of Biophotonics, 2022, ISSN 1864-063X
Publisher: Wiley - VCH Verlag GmbH & CO. KGaA
DOI: 10.1002/jbio.202200032

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