Description du projet
Des biocapteurs à base de salive pour améliorer la santé
La bouche et le corps sont indissociables. La salive a été décrite comme le miroir du corps et est de plus en plus reconnue comme un intéressant fluide de diagnostic. Elle sert de baromètre physiologique. Le projet SALSETH, financé par l’UE, facilite l’échange de connaissances, d’aptitudes, de compétences et de capacités (via les détachements) entre les meilleures organisations internationales participantes d’Australie, d’Allemagne, d’Espagne, d’Italie, de Malaisie, de Pologne, de Serbie et d’Ukraine. Le projet rassemblera l’expertise requise pour réaliser des avancées de pointe dans des matériaux biocompatibles naturels et bio-inspirés, ainsi que des capteurs comestibles à base d’aliments afin de détecter rapidement des biomarqueurs importants à partir de la salive. Il développera également un dispositif électronique intelligent externe afin de lire sans fil les données issues des capteurs et des dispositifs microfluidiques pour l’administration optimale de médicaments.
Objectif
Oral hygiene is the cornerstone of good oral health and World Health Organization recognizes oral health as an integral part of systemic health. Among the non-invasive organic fluids, saliva is one of the most preferable and practical specimens for oral and systemic health monitoring as it is readily available and easily collected and stored. Saliva is frequently called a “mirror of the body” since it can reflect both the physiological and pathological conditions in the entire human organism. The SALSETH project proposal facilitates exchange of knowledge, skills, competencies and capabilities (through secondments) of 8 internationally top-ranking participating organizations (4 from academic sector and 4 SMEs) from Germany, Italy, Spain, Poland, Serbia, Ukraine, Malaysia and Australia. This project proposal promotes international and intersectoral collaboration between participating institutions, bringing experts from different fields of science in a unique R&I set up. The SALSETH brings together expertise of the respectable institutions to reach beyond the-state-of-the-art advances in: (1) natural and bio-inspired biocompatible materials; (2) edible food-based sensors which can promptly detect important biomarkers from saliva; (3) external smart electronic device for wireless reading data from sensors; and (4) microfluidic devices for optimal administration of drugs or essential oils as a main part of the intraoral appliances for better oral and systemic health. Through carefully designed secondments, the seconded staff will work on significant technological breakthrough in salivary theranostics for personalized dental bio-medicine. This interdisciplinary project offers an excellent research oriented environment for the personal and professional growth of the involved staff members. The SALSETH will open possibilities of salivary diagnostics for personalized individual medicine applications including clinical treatment options and outcome evaluation predictions.
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MSCA-RISE - Marie Skłodowska-Curie Research and Innovation Staff Exchange (RISE)Coordinateur
21000 Novi Sad
Serbie