Shaping the Mechano-Pharmacological properties of Microparticles and Extracellular Vesicles for the Treatment of Osteoarthritis

Project Information

MEPHOS

Grant agreement ID: 872648

DOI

10.3030/872648

Project closed

EC signature date 27 November 2019

Start date 1 April 2020

End date 30 September 2025

Funded under

• EXCELLENT SCIENCE - Marie Skłodowska-Curie Actions

Total cost

€ 906 200,00

EU contribution

€ 864 800,00

Coordinated by

FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA
Italy

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Deliverables

Open Research Data Pilot (1)

Data Management Plan

Publications

Peer reviewed articles (6)

Management of osteoarthritis: From drug molecules to nano/micromedicines

Author(s): Martina Di Francesco,Agnese Fragassi,Martina Pannuzzo,Miguel Ferreira,Sayanti Brahmachari,Paolo Decuzzi
Published in: Wiley Interdisciplinary Reviews: Nanomedicine and Nanobiotechnology, Issue 19390041, 2022, ISSN 1939-0041
Publisher: John Wiley & Sons Inc.
DOI: 10.1002/wnan.1780

Top-Down Fabricated microPlates for Prolonged, Intra-articular Matrix Metalloproteinase 13 siRNA Nanocarrier Delivery to Reduce Post-traumatic Osteoarthritis

Author(s): Sean K Bedingfield, Juan M. Colazo, Martina Di Francesco, Fang Yu, Danielle D. Liu, Valentina Di Francesco, Lauren E. Himmel, Mukesh K. Gupta, Hongsik Cho, Karen A. Hasty, Paolo Decuzzi, and Craig L. Duvall
Published in: ACS Nano, Issue 19360851, 2021, Page(s) 14475–14491, ISSN 1936-0851
Publisher: American Chemical Society
DOI: 10.1021/acsnano.1c04005

Shape-Defined microPlates for the Sustained Intra-articular Release of Dexamethasone in the Management of Overload-Induced Osteoarthritis.

Author(s): Martina Di Francesco; Sean K. Bedingfield; Valentina Di Francesco; Valentina Di Francesco; Juan M. Colazo; Fang Yu; Luca Ceseracciu; Elena Bellotti; Daniele Di Mascolo; Miguel Ferreira; Lauren E. Himmel; Craig L. Duvall; Paolo Decuzzi
Published in: ACS Applied Materials and Interfaces, Issue 10895639, 2021, Page(s) 31379-31392, ISSN 1089-5639
Publisher: American Chemical Society
DOI: 10.1021/acsami.1c02082

Shape-specific microfabricated particles for biomedical applications: a review

Author(s): Thomas L. Moore; Alexander B. Cook; Elena Bellotti; Roberto Palomba; Purnima Manghnani; Raffaele Spanò; Sayanti Brahmachari; Martina Di Francesco; Anna Lisa Palange; Daniele Di Mascolo; Paolo Decuzzi
Published in: Drug Delivery and Translational Research, Issue 2190393X, 2022, Page(s) 2019–2037, ISSN 2190-393X
Publisher: Springer Pub. Co.,
DOI: 10.1007/s13346-022-01143-4

Insulin Granule-Loaded MicroPlates for Modulating Blood Glucose Levels in Type-1 Diabetes.

Author(s): Rosita Primavera; Rosita Primavera; Elena Bellotti; Daniele Di Mascolo; Martina Di Francesco; Jing Wang; Bhavesh D. Kevadiya; Angelo De Pascale; Avnesh S. Thakor; Paolo Decuzzi
Published in: ACS Appl Mater Interface, Issue 3, 2021, ISSN 1944-8244
Publisher: American Chemical Society
DOI: 10.1021/acsami.1c16768

Sustained inhibition of CC-chemokine receptor-2 via intraarticular deposition of polymeric microplates in post-traumatic osteoarthritis

Author(s): Huseyin Ozkan, Martina Di Francesco, Helen Willcockson, José Valdés-Fernández, Valentina Di Francesco, Froilán Granero-Moltó, Felipe Prósper, Paolo Decuzzi & Lara Longobardi
Published in: Drug Delivery and Translational Research, Issue 13, 2023, Page(s) 689–701, ISSN 2190-393X
Publisher: Springer Pub. Co.,
DOI: 10.1007/s13346-022-01235-1