Project description DEENESFRITPL Healthy living in the city People are moving from rural areas to cities in search of a better life. While city life has its obvious charms and advantages, there is also a downside. For instance, the environment we live in accounts for an estimated 70 % of the chronic disease burden. The EU-funded EXPANSE project will study the urban exposome, which is the sum of all non-genetic drivers of health and disease. Its aim is to identify ways to maximise one’s health in a modern urban environment. To do so, EXPANSE will examine the health and exposome data of 55 million Europeans. In addition, in-depth omics analyses of well-characterised cohorts will be conducted. The project will establish the largest European urban exposome consortium to date and build upon the methodological development and insights gained from the first generation of exposome projects. Show the project objective Hide the project objective Objective By 2030 more than 80% of Europe’s population will live and interact with a complex urban environment, consisting of a mixture of social and environmental factors. These factors include: where we live and work, where and what we eat, our social network, and what chemical substances we are exposed to. Individually or collectively these factors, known as the Urban Exposome, have an often modifiable impact on our health and provide important targets to improve population health. By studying the impact of the Urban Exposome on the major contributors to Europe’s burden of disease: Cardio-Metabolic and Pulmonary Disease, EXPANSE will address one of the most pertinent questions for urban planners, policy makers, and European citizens: “How to maximize one’s health in a modern urban environment?”.EXPANSE will take the next step in Exposome research by: 1) bringing together the Exposome and health data of more than 55 million Europeans in administrative cohorts, in-depth Exposome, phenotype, and OMICs information for more than 2 million Europeans, and personalized Exposome assessment for 5,000 individuals living in five “Urban Labs”; 2) applying a novel approach to use ultra-high-resolution mass-spectrometry to agnostically screen for exogenous chemicals in 10,000 blood samples; 3) studying the evolution of the Exposome and health through the life-course via both (matured) birth and adult cohorts; and 4) evaluating the impact of changes in the Urban Exposome on the burden of Cardio-Metabolic and Pulmonary Disease.EXPANSE will translate its insights and innovations into research and dissemination tools that will be openly accessible via the EXPANSE toolbox. By applying innovative ethics-by-design throughout the project, the social and ethical acceptability of these tools will be safeguarded. Tool discoverability and accessibility will be stimulated through the EXPANSE hub in which citizens, public sector policy makers, and private sector companies collectively participate. EXPANSE is part of the European Human Exposome Network comprised of 9 projects selected from this same call Keywords Urban Exposome Cardiometabolomic and Pulmonary Health Metabolomics Programme(s) H2020-EU.3.1. - SOCIETAL CHALLENGES - Health, demographic change and well-being Main Programme H2020-EU.3.1.2. - Preventing disease Topic(s) SC1-BHC-28-2019 - The Human Exposome Project: a toolbox for assessing and addressing the impact of environment on health Call for proposal H2020-SC1-BHC-2018-2020 See other projects for this call Sub call H2020-SC1-2019-Single-Stage-RTD Funding Scheme RIA - Research and Innovation action Coordinator UNIVERSITEIT UTRECHT Net EU contribution € 2 073 925,00 Address Heidelberglaan 8 3584 CS Utrecht Netherlands See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Participants (20) Sort alphabetically Sort by Net EU contribution Expand all Collapse all KAROLINSKA INSTITUTET Sweden Net EU contribution € 677 356,84 Address Nobels vag 5 17177 Stockholm See on map Region Östra Sverige Stockholm Stockholms län Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,04 HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM FUER GESUNDHEIT UND UMWELT GMBH Germany Net EU contribution € 559 591,29 Address Ingolstadter landstrasse 1 85764 Neuherberg See on map Region Bayern Oberbayern München, Landkreis Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SCHWEIZERISCHES TROPEN UND PUBLIC HEALTH INSTITUT Switzerland Net EU contribution € 976 270,39 Address Kreuzstrasse 2 4123 Allschwil See on map Region Schweiz/Suisse/Svizzera Nordwestschweiz Basel-Landschaft Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 IMPERIAL COLLEGE OF SCIENCE TECHNOLOGY AND MEDICINE United Kingdom Net EU contribution € 937 385,78 Address South kensington campus exhibition road SW7 2AZ London See on map Region London Inner London — West Westminster Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIVERSITAIR MEDISCH CENTRUM UTRECHT Netherlands Net EU contribution € 743 909,91 Address Heidelberglaan 100 3584 CX Utrecht See on map Region West-Nederland Utrecht Utrecht Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 STICHTING VUMC Netherlands Net EU contribution € 338 283,23 Address De boelelaan 1117 1081 HV Amsterdam See on map Region West-Nederland Noord-Holland Groot-Amsterdam Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE France Net EU contribution € 333 507,75 Address Rue de tolbiac 101 75654 Paris See on map Region Ile-de-France Ile-de-France Paris Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 CENTRE INTERNATIONAL DE RECHERCHE SUR LE CANCER France Net EU contribution € 1 266 093,43 Address 25 avenue tony garnier 69007 Lyon 7eme See on map Region Auvergne-Rhône-Alpes Rhône-Alpes Rhône Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK United States Net EU contribution € 687 259,89 Address Amsterdam avenue 1210 room 10027 7003 New york See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI Participation ended United States Net EU contribution € 403 907,56 Address One gustave l levy place box 1075 10029 6574 New york See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 TARTU ULIKOOL Estonia Net EU contribution € 546 305,15 Address Ulikooli 18 51005 Tartu See on map Region Eesti Eesti Lõuna-Eesti Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 INSTYTUT MEDYCYNY PRACY IMIENIA PROF. DRA MED. JERZEGO NOFERA W LODZI Poland Net EU contribution € 219 630,06 Address Ul sw teresy od dzieciatka jezus 8 91 348 Lodz See on map Region Makroregion centralny Łódzkie Łódzki Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 FUNDACION PRIVADA INSTITUTO DE SALUD GLOBAL BARCELONA Spain Net EU contribution € 566 223,29 Address C rossello 132 planta 05 08036 Barcelona See on map Region Este Cataluña Barcelona Activity type Research Organisations Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 AZIENDA SANITARIA LOCALE ROMA 1 Italy Net EU contribution € 277 861,58 Address Borgo santo spirito 3 00198 Roma See on map Region Centro (IT) Lazio Roma Activity type Public bodies (excluding Research Organisations and Secondary or Higher Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 ETHNIKO KAI KAPODISTRIAKO PANEPISTIMIO ATHINON Greece Net EU contribution € 427 195,24 Address 6 christou lada str 10561 Athina See on map Region Αττική Aττική Κεντρικός Τομέας Αθηνών Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 Masarykova univerzita Czechia Net EU contribution € 327 229,09 Address Zerotinovo namesti 9 601 77 Brno See on map Region Česko Jihovýchod Jihomoravský kraj Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 GAME SOLUTIONS LAB BV Netherlands Net EU contribution € 127 744,93 Address Vonderweg 1 5611 BK Eindhoven See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region Zuid-Nederland Noord-Brabant Zuidoost-Noord-Brabant Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 SODAQ HOLDING BV Netherlands Net EU contribution € 142 808,79 Address Bussumerstraat 34 1211 BL Hilversum See on map SME The organization defined itself as SME (small and medium-sized enterprise) at the time the Grant Agreement was signed. Yes Region West-Nederland Noord-Holland Het Gooi en Vechtstreek Activity type Private for-profit entities (excluding Higher or Secondary Education Establishments) Links Contact the organisation Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 UNIWERSYTET JAGIELLONSKI Poland Net EU contribution € 75 000,00 Address Ul golebia 24 31-007 Krakow See on map Region Makroregion południowy Małopolskie Miasto Kraków Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00 EMORY UNIVERSITY NON PROFIT CORP United States Net EU contribution € 286 417,79 Address Clifton road, ne, 4th floor 1599 30322 Atlanta See on map Activity type Higher or Secondary Education Establishments Links Contact the organisation Opens in new window Website Opens in new window Participation in EU R&I programmes Opens in new window HORIZON collaboration network Opens in new window Other funding € 0,00