Deliverables Documents, reports (10) Report describing tools and maps for the social environment This report will describe the tools and maps that will be used in EXPANSE to quantify the social environment component of the External Exposome Report on residential relocation in existing cohorts Report on residential relocation in existing cohorts Report describing tools and maps for the physico-chemical environment This report will describe the tools and maps that will be used in EXPANSE to quantify the physicochemical environment component of the External Exposome List of Working Groups and ToR for the WGs A first set of working groups will be made and Term of Reference for the WGs will be specified including the selection of work group leaders coleads and members Report on measurement error correction methodology Report in which a new measurement error correction methodology applicable to Exposome studies is described Report describing the first meeting to discuss the design of the long-term research infrastructure Report describing the first meeting to discuss the design of the longterm research infrastructure Handover document to next coordinating team Document summarising network activities and ongoing activities to facilitate a smooth transition to the next team. This document will include concise reports from working groups. Report describing tools and maps for the built environment Report describing tools and maps for the built environment component of the External Exposome Ethics by Design recommendations reports (months 12, 24, 36, 48 and 60) Ethics by Design recommendations reports (months 12, 24, 36, 48 and 60), incorporating the Report describing tools and maps for the food environment This report will describe the tools and maps that will be used in EXPANSE to quantify the food environment component of the External Exposome Websites, patent fillings, videos etc. (2) EXPANSE Website and social media accounts EXPANSE Website and social media accounts EXPANSE Brochure EXPANSE Brochure Publications Peer reviewed articles (43) Epigenetic mechanisms of lung carcinogenesis involve differentially methylated CpG sites beyond those associated with smoking Author(s): Petrovic D, Bodinier B, Dagnino S, Whitaker M, Karimi M, Campanella G, Haugdahl Nost T, Polidoro S, Palli D, Krogh V, Tumino R, Sacerdote C, Panico S, Lund E, Dugue PA, Giles GG, Severi G, Southey M, Vineis P, Stringhini S, Bochud M, Sandanger TM, Vermeulen RCH, Guida F, Chadeau-Hyam M. Published in: European Journal of Epidemiology, 2022, ISSN 0393-2990 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10654-022-00877-2 Twin peaks: The Omicron SARS-CoV-2 BA.1 and BA.2 epidemics in England Author(s): Elliott P, Eales O, Steyn N, Tang D, Bodinier B, Wang H, Elliott J, Whitaker M, Atchison C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Ward H, Darzi A, Cooke GS, Donnelly CA, Chadeau-Hyam M Published in: Science, 2022, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.abq4411 Effects of pesticide exposure on oxidative stress and DNA methylation urinary biomarkers in Czech adults and children from the CELSPAC-SPECIMEn cohort Author(s): Tomas Janos, Ilse Ottenbros,Lucie Blahov, Petr Senka, Libor Sulca, Nina Palesova, Jessica Sheardova, Jelle Vlaanderen, Pavel Cupr Published in: Environmental Research, Issue Volume 222 115368, 2023, ISSN 1096-0953 Publisher: Elsevier DOI: 10.1016/j.envres.2023.115368 Agent-based modeling of urban exposome interventions: prospects, model architectures, and methodological challenges Author(s): Tabea Sonnenschein, Simon Scheider, G Ardine de Wit, Cathryn C Tonne, Roel Vermeulen Published in: Exposome, Issue Volume 2 / 2022, 2022, ISSN 2635-2265 Publisher: Oxford University Press DOI: 10.1093/exposome/osac009 A Knowledge Transfer Approach to Map Long-Term Concentrations of Hyperlocal Air Pollution from Short-Term Mobile Measurements Author(s): Yuan, Z., Kerckhoffs, J., Hoek, G., & Vermeulen, R. Published in: Environmental Science & Technology, Issue Volume 56 / 2022, 2022, Page(s) 13820 - 13828, ISSN 1520-5851 Publisher: ACS Publications DOI: 10.1021/acs.est.2c05036 Mixed-Effects Modeling Framework for Amsterdam and Copenhagen for Outdoor NO2 Concentrations Using Measurements Sampled with Google Street View Cars Author(s): Jules Kerckhoffs*, Jibran Khan, Gerard Hoek, Zhendong Yuan, Thomas Ellermann, Ole Hertel, Matthias Ketzel, Steen Solvang Jensen, Kees Meliefste, and Roel Vermeulen Published in: Environmental Science and Technology, Issue 2022, 2022, ISSN 0013-936X Publisher: American Chemical Society DOI: 10.1021/acs.est.1c05806 Predictive symptoms for COVID-19 in the community: REACT-1 study of over 1 million people Author(s): Joshua Elliott, Matthew Whitaker, Barbara Bodinier, Oliver Eales, Steven Riley, Helen Ward, Graham Cooke, Ara Darzi, Marc Chadeau-Hyam, Paul Elliott Published in: PLOS Medicine, Issue 18/9, 2021, Page(s) e1003777, ISSN 1549-1676 Publisher: PLOS DOI: 10.1371/journal.pmed.1003777 Allergies to food and airborne allergens in children and adolescents: role of epigenetics in a changing environment. Author(s): Melén, E., Koppelman, G. H., Vicedo-Cabrera, A. M., Andersen, Z. J., & Bunyavanich, S. Published in: The Lancet Child & Adolescent Health, Issue Volume 6 / 2022, 2022, Page(s) 810 - 819, ISSN 2352-4642 Publisher: Elsevier DOI: 10.1016/s2352-4642(22)00215-2 Machine learning approaches to characterize the obesogenic urban exposome Author(s): Haykanush Ohanyan, Lützen Portengen, Anke Huss, Eugenio Traini, Joline W.J. Beulens, Gerard Hoek, Jeroen Lakerveld, Roel Vermeulen, Published in: Environment International, Issue Volume 158 / 2022, 2021, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2021.107015 Environmental risk factors of type 2 diabetes—an exposome approach Author(s): Joline W. J. Beulens, Maria G. M. Pinho, Taymara C. Abreu, Nicole R. den Braver, Thao M. Lam, Anke Huss, Jelle Vlaanderen, Tabea Sonnenschein, Noreen Z. Siddiqui, Zhendong Yuan, Jules Kerckhoffs, Alexandra Zhernakova, Milla F. Brandao Gois & Roel C. H. Vermeulen Published in: Diabetologia, Issue Volume 65 / 2022, 2021, Page(s) 263 - 274, ISSN 1432-0428 Publisher: Journal of the European Association for the Study of Diabetes (EASD). DOI: 10.1007/s00125-021-05618-w Dynamics of a national Omicron SARS-CoV-2 epidemic during January 2022 in England Author(s): Elliott P, Eales O, Bodinier B, Tang D, Wang H, Jonnerby J, Haw D, Elliott J, Whitaker M, Walters CE, Atchison C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Ward H, Darzi A, Cooke GS, Chadeau-Hyam M, Donnelly CA Published in: Nature Communications, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-32121-6 Developing the building blocks to elucidate the impact of the urban exposome on cardiometabolic-pulmonary disease Author(s): Jelle Vlaanderen, Kees de Hoogh, Gerard Hoek, Annette Peters, Nicole Probst-Hensch, Augustin Scalbert, Erik Melén, Cathryn Tonne, G. Ardine de Wit, Marc Chadeau-Hyam, Klea Katsouyanni, Tõnu Esko, Karin R. Jongsma, Roel Vermeulen Published in: Environmental Epidemiology, Issue 5/4, 2021, Page(s) e162, ISSN 2474-7882 Publisher: Wolters Kluwer Health DOI: 10.1097/ee9.0000000000000162 Merging the exposome into an integrated framework for “omics” sciences. Author(s): Elliott J. Price, Chiara M. Vitale, Gary W. Miller, Arthur David, Robert Barouki, Karine Audouze, Douglas I. Walker, Jean-Philippe Antignac, Xavier Coumoul, Vincent Bessonneau, Jana Klánová, Published in: iScience, Issue Volume 25 / 2022, 2022, ISSN 2589-0042 Publisher: 2589-0042 DOI: 10.1016/j.isci.2022.103976 The human microbial exposome: expanding the Exposome-Explorer database with gut microbial metabolites. Author(s): Vanessa Neveu, Geneviève Nicolas, Adam Amara, Reza M. Salek, Augustin Scalbert Published in: Scientific reports, Issue Volume 13 / 2023, 2023, ISSN 2045-2322 Publisher: Nature Publishing Group DOI: 10.1038/s41598-022-26366-w Ultra-processed food consumption patterns among older adults in the Netherlands and the role of the food environment Author(s): Pinho MGM, Lakerveld J, Harbers MC, Sluijs I, Vermeulen R, Huss A, Boer JMA, Verschuren WMM, Brug J, Beulens JWJ, Mackenbach JD Published in: European Journal of Nutrition, Issue Volume 60 / 2021, 2020, Page(s) 2567 - 2580, ISSN 1436-6215 Publisher: Springer Nature DOI: 10.1007/s00394-020-02436-5 Hallmarks of environmental insults Author(s): Annette Peters, Tim S. Nawrot, Andrea A. Baccarelli Published in: Cell, Issue 184/6, 2021, Page(s) 1455-1468, ISSN 0092-8674 Publisher: Cell Press DOI: 10.1016/j.cell.2021.01.043 Narrative review of citizen science in environmental epidemiology: Setting the stage for co-created research projects in environmental epidemiology Author(s): Frederique Froeling, Florence Gignac, Gerard Hoek, Roel Vermeulen, Mark Nieuwenhuijsen, Antonella Ficorilli, Bruna De Marchi, Annibale Biggeri, David Kocman, Johanna Amalia Robinson, Regina Grazuleviciene, Sandra Andrusaityte, Valeria Righi, Xavier Basagaña Published in: Environment International, Issue 152, 2021, Page(s) 106470, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2021.106470 Survey-derived activity space-based exposures to fast food outlets and their cross-sectional associations with use of fast food outlets, diet quality and BMI Author(s): Mackenbach JD, Widener MJ, van der Gaag E, Pinho MGM Published in: Health & Place, Issue Volume 79 / 2023, 2023, ISSN 1353-8292 Publisher: Elsevier BV DOI: 10.1016/j.healthplace.2023.102966 Variant-specific symptoms of COVID-19 in a study of 1,542,510 adults in England Author(s): Whitaker M, Elliott J, Bodinier B, Barclay W, Ward H, Cooke G, Donnelly CA, Chadeau-Hyam M, Elliott P. Published in: Nature Communications, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-34244-2 Genotoxic effects of transboundary pollutants in Pinus mugo in the high mountain habitats Author(s): Eva Klemmová Gregušková, Daniel Mihálik, Ján Kraic, Michaela Mrkvová, Jozef Sokol, Petr Gregor, Aneta Rafajová, Pavel Čupr, Published in: Ecological Indicators, Issue Volume 140 / 2022, 2022, ISSN 1872-7034 Publisher: Elsevier DOI: 10.1016/j.ecolind.2022.109009 Dynamics of competing SARS-CoV-2 variants during the Omicron epidemic in England. Author(s): Eales O, de Oliveira Martins L, Page AJ, Wang H, Bodinier B, Tang D, Haw D, Jonnerby J, Atchison C, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Elliott P, Donnelly CA, Chadeau-Hyam M. Published in: Nature Communications, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-32096-4 Hyperlocal variation of nitrogen dioxide, black carbon, and ultrafine particles measured with Google Street View cars in Amsterdam and Copenhagen Author(s): Jules Kerckhoffs, Jibran Khan, Gerard Hoek, Zhendong Yuan, Ole Hertel, Matthias Ketzel, Steen Solvang Jensen, Fares Al Hasan, Kees Meliefste, Roel Vermeulen, Published in: Environment International, Issue Volume 170 / 2022, 2022, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2022.107575 Spirometric phenotypes from early childhood to young adulthood: a Chronic Airway Disease Early Stratification study Author(s): Gang Wang, Jenny Hallberg, Dimitrios Charalampopoulos, Maribel Casas Sanahuja, Robab Breyer-Kohansal, Arnulf Langhammer, Raquel Granell, Judith M. Vonk, Annemiek Mian, Núria Olvera, Lisbeth Mølgaard Laustsen, Eva Rönmark, Alicia Abellan, Alvar Agusti, Syed Hasan Arshad, Anna Bergström, H. Marike Boezen, Marie-Kathrin Breyer, Otto Burghuber, Anneli Clea Bolund, Adnan Custovic, Graham Devereux, Published in: ERJ open research, Issue 7: 00457-2021, 2021, ISSN 2312-0541 Publisher: European Respiratory Society DOI: 10.1183/23120541.00457-2021 Breakthrough SARS-CoV-2 infections in double and triple vaccinated adults and single dose vaccine effectiveness among children in Autumn 2021 in England: REACT-1 study Author(s): Chadeau-Hyam M, Eales O, Bodinier B, Wang H, Haw D, Whitaker M, Elliott J, Walters CE, Jonnerby J, Atchison C, Diggle PJ, Page AJ, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Donnelly CA, Elliott P Published in: EClinicalMedicine, 2022, ISSN 2589-5370 Publisher: Elsevier DOI: 10.1016/j.eclinm.2022.101419 Persistent COVID-19 symptoms in a community study of 606,434 people in England Author(s): Whitaker M, Elliott J, Chadeau-Hyam M, Riley S, Darzi A, Cooke G, Ward H, Elliott P Published in: Nature Communications, 2022, ISSN 2041-1723 Publisher: Nature Publishing Group DOI: 10.1038/s41467-022-29521-z Education, biological ageing, all-cause and cause-specific mortality and morbidity: UK biobank cohort study Author(s): Marc Chadeau-Hyam, Barbara Bodinier, Roel Vermeulen, Maryam Karimi, Verena Zuber, Raphaële Castagné, Joshua Elliott, David Muller, Dusan Petrovic, Matthew Whitaker, Silvia Stringhini, Ioanna Tzoulaki, Mika Kivimäki, Paolo Vineis, Paul Elliott, Michelle Kelly-Irving, Cyrille Delpierre Published in: EClinicalMedicine, Issue 29-30, 2020, Page(s) 100658, ISSN 2589-5370 Publisher: Elsevier DOI: 10.1016/j.eclinm.2020.100658 Rapid increase in Omicron infections in England during December 2021: REACT-1 study. Author(s): Elliott P, Bodinier B, Eales O, Wang H, Haw D, Elliott J, Whitaker M, Jonnerby J, Tang D, Walters CE, Atchison C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Ward H, Darzi A, Cooke GS, Chadeau-Hyam M, Donnelly CA. Published in: Science, 2022, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.abn8347 Analytical strategies for chemical exposomics: exploring limits and feasibility Author(s): Chiara Maria Vitale, Elliott J Price, Gary W Miller, Arthur David, Jean-Philippe Antignac, Robert Barouki, Jana Klánová, Published in: Exposome, Issue Volume 1 / 2021, 2021, ISSN 2635-2265 Publisher: Oxford University Press DOI: 10.1093/exposome/osab003 Residential proximity to livestock animals and mortality from respiratory diseases in The Netherlands: A prospective census-based cohort study Author(s): Mariana Simões, Nicole Janssen, Dick Heederik, Lidwien Smit, Roel Vermeulen, Anke Huss Published in: Environment International, Issue Volume 161 / 2022, 2022, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2022.107140 Omicron SARS-CoV-2 epidemic in England during February 2022: A series of cross-sectional community surveys Author(s): Chadeau-Hyam M, Tang D, Eales O, Bodinier B, Wang H, Jonnerby J, Whitaker M, Elliott J, Haw D, Walters CE, Atchison C, Diggle PJ, Page AJ, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Donnelly CA, Elliott P. Published in: Lancet Regional Health Europe, 2022, ISSN 2666-7762 Publisher: Elsevier DOI: 10.1016/j.lanepe.2022.100462 Modelling nationwide spatial variation of ultrafine particles based on mobile monitoring Author(s): Jules Kerckhoffs, Gerard Hoek, Ulrike Gehring, Roel Vermeulen Published in: Environment International, Issue 154, 2021, Page(s) 106569, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2021.106569 City-scale assessment of long-term air quality impacts on the respiratory and cardiovascular health Author(s): Libor Šulc, Petr Gregor, Jirí Kalina, Ondrej Mikes, Tomás Janos and Pavel Cupr Published in: Frontiers in Public Health, Issue Volume 10 / 2022, 2022, ISSN 2296-2565 Publisher: Lausanne Frontiers Media S.A DOI: 10.3389/fpubh.2022.1006536 Impact of long-term exposure to PM2.5 on peripheral blood gene expression pathways involved in cell signaling and immune response Author(s): Jelle Vlaanderen, Roel Vermeulen, Matthew Whitaker, Marc Chadeau-Hyam, Jouke-Jan Hottenga, Eco de Geus, Gonneke Willemsen, Brenda W.J.H. Penninx, Rick Jansen, Dorret I. Boomsma, Published in: Environment International, Issue Volume 168 / 2022, 2022, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2022.107491 Air pollution, metabolites and respiratory health across the life-course Author(s): Gruzieva O, Jeong A, He S, Yu Z, de Bont J, Pinho MGM, Eze IC, Kress S, Wheelock CE, Peters A, Vlaanderen J, de Hoogh K, Scalbert A, Chadeau-Hyam M, Vermeulen RCH, Gehring U, Probst-Hensch N, Melén E. Published in: European respiratory review, Issue Volume 31 / 2022, 2022, ISSN 1600-0617 Publisher: European respiratory society DOI: 10.1183/16000617.0038-2022 COVID-19 mortality in the UK Biobank cohort: revisiting and evaluating risk factors Author(s): Joshua Elliott, Barbara Bodinier, Matthew Whitaker, Cyrille Delpierre, Roel Vermeulen, Ioanna Tzoulaki, Paul Elliott, Marc Chadeau-Hyam Published in: European Journal of Epidemiology, Issue 36/3, 2021, Page(s) 299-309, ISSN 0393-2990 Publisher: Kluwer Academic Publishers DOI: 10.1007/s10654-021-00722-y Assessing How Social Exposures Are Integrated in Exposome Research: A Scoping Review Author(s): Neufcourt L, Castagné R, Mabile L, Khalatbari-Soltani S, Delpierre C, Kelly-Irving M Published in: Environmental Health Perspectives, Issue Volume 130 / 2022, 2022, ISSN 0091-6765 Publisher: US Department of Health and Human Services DOI: 10.1289/ehp11015 An annotation database for chemicals of emerging concern in exposome research Author(s): Jeroen Meijer, Marja Lamoree, Timo Hamers, Jean-Philippe Antignac, Sébastien Hutinet, Laurent Debrauwer, Adrian Covaci, Carolin Huber, Martin Krauss, Douglas I. Walker, Emma L. Schymanski, Roel Vermeulen, Jelle Vlaanderen Published in: Environment International, Issue 152, 2021, Page(s) 106511, ISSN 0160-4120 Publisher: Pergamon Press Ltd. DOI: 10.1016/j.envint.2021.106511 Where do Dutch adults obtain their snack foods? Cross-sectional exploration of individuals’ interactions with the food environment Author(s): Mackenbach JD, Hobbs M, Pinho MGM Published in: Health & Place, Issue Volume 75 / 2022, 2022, ISSN 1353-8292 Publisher: Elsevier BV DOI: 10.1016/j.healthplace.2022.102802 Prospective Identification of Elevated Circulating CDCP1 in Patients Years before Onset of Lung Cancer Author(s): Sonia Dagnino, Barbara Bodinier, Florence Guida, Karl Smith-Byrne, Dusan Petrovic, Matthew D. Whitaker, Therese Haugdahl Nøst, Claudia Agnoli, Domenico Palli, Carlotta Sacerdote, Salvatore Panico, Rosario Tumino, Matthias B. Schulze, Mikael Johansson, Pekka Keski-Rahkonen, Augustin Scalbert, Paolo Vineis, Mattias Johansson, Torkjel M. Sandanger, Roel C.H. Vermeulen, Marc Chadeau-Hyam Published in: Cancer Research, Issue 81/13, 2021, Page(s) 3738-3748, ISSN 0008-5472 Publisher: American Association for Cancer Research DOI: 10.1158/0008-5472.can-20-3454 SARS-CoV-2 infection and vaccine effectiveness in England (REACT-1): a series of cross-sectional random community surveys. Author(s): Chadeau-Hyam M, Wang H, Eales O, Haw D, Bodinier B, Whitaker M, Walters CE, Ainslie KEC, Atchison C, Fronterre C, Diggle PJ, Page AJ, Trotter AJ, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Donnelly CA, Elliott P Published in: The Lancet Respiratory Medicine, 2022, ISSN 2213-2600 Publisher: Elsevier Limited DOI: 10.1016/s2213-2600(21)00542-7 Risk factors for positive and negative COVID-19 tests: a cautious and in-depth analysis of UK biobank data Author(s): Marc Chadeau-Hyam, Barbara Bodinier, Joshua Elliott, Matthew D Whitaker, Ioanna Tzoulaki, Roel Vermeulen, Michelle Kelly-Irving, Cyrille Delpierre, Paul Elliott Published in: International Journal of Epidemiology, Issue 49/5, 2020, Page(s) 1454-1467, ISSN 0300-5771 Publisher: Oxford University Press DOI: 10.1093/ije/dyaa134 SARS-CoV-2 lineage dynamics in England from September to November 2021: high diversity of Delta sub-lineages and increased transmissibility of AY.4.2. Author(s): Eales O, Page AJ, de Oliveira Martins L, Wang H, Bodinier B, Haw D, Jonnerby J, Atchison C, Consortium C-GU, Ashby D, Barclay W, Taylor G, Cooke G, Ward H, Darzi A, Riley S, Chadeau-Hyam M, Donnelly CA, Elliott P. Published in: BMC infectious diseases, Issue Volume 22 / 2022, 2022, Page(s) 647, ISSN 1471-2334 Publisher: BioMed Central DOI: 10.1186/s12879-022-07628-4 The exposome and health: Where chemistry meets biology Author(s): Roel Vermeulen, Emma L. Schymanski, Albert-László Barabási, Gary W. Miller Published in: Science, Issue 367/6476, 2020, Page(s) 392-396, ISSN 0036-8075 Publisher: American Association for the Advancement of Science DOI: 10.1126/science.aay3164 Other (1) Invited Perspective: Inroads to Biology-Informed Exposomics Author(s): Vermeulen R. Published in: Environmental Health Perspectives, Issue Volume 130 / 2022, 2022, ISSN 1552-9924 Publisher: JSTorg DOI: 10.1289/ehp12224 Non-peer reviewed articles (1) Scrutinizing Privacy in Multi-Omics Research: How to Provide Ethical Grounding for the Identification of Privacy-Relevant Data Properties Author(s): C.W. Safarlou, A.L. Bredenoord, R. Vermeulen & K.R. Jongsma Published in: The American Journal of Bioethics, Issue Volume 21, issue 12, 2021, Page(s) 73-75, ISSN 1526-5161 Publisher: MIT Press DOI: 10.1080/15265161.2021.1991041 Searching for OpenAIRE data... There was an error trying to search data from OpenAIRE No results available
