3D Printed-Matrix Assisted Chemically Modified RNAs Bone Regenerative Therapy for Trauma and Osteoporotic Patients

Deliverables

Evaluation of the stability, protection, release, transfection capacity and toxicity of cmRNA delivery reagents

Evaluation of the stability protection release transfection capacity and toxicity of cmRNA delivery reagents

cmRNA delivery system in fHA - CaP. Transfection assay on cell lines

cmRNA delivery system in fHA – CaP. Transfection assay on cell lines

Public project website Social media accounts LinkedIn, Twitter

Characterization of vectors

Publications

Effect on Rheological Properties and 3D Printability of Biphasic Calcium Phosphate Microporous Particles in Hydrocolloid-Based Hydrogels

Author(s): Helena Herrada-Manchón; David Rodríguez-González; Manuel Alejandro Fernández; Nathan William Kucko; Florence Barrère-de Groot; Enrique Aguilar
Published in: https://www.scopus.com/inward/record.uri?eid=2-s2.0-85123750749&doi=10.3390%2fgels8010028&partnerID=40&md5=66b26a13c70c90eeb6ed7721859e0b5a, Issue 1, 2022, ISSN 2310-2861
Publisher: MDPI
DOI: 10.3390/gels8010028

Osteoinductive calcium phosphate with submicron topography as bone graft substitute for maxillary sinus floor augmentation: A translational study

Author(s): Lukas A. van Dijk, Nard G. Janssen, Silke J. Nurmohamed, Marvick S. M. Muradin, Alessia Longoni, Robbert C. Bakker, Florence G. de Groot, Joost D. de Bruijn, Debby Gawlitta, Antoine J. W. P. Rosenberg
Published in: Clinical Oral Implants Research, Issue 34, 2023, Page(s) 177-195, ISSN 0905-7161
Publisher: Blackwell Publishing Inc.
DOI: 10.1111/clr.14028

3D printing of inorganic-biopolymer composites for bone regeneration

Author(s): Daphne van der Heide, Gianluca Cidonio, Martin James Stoddart and Matteo D'Este
Published in: Biofabrication, Issue Volume 14, Number 4, 2022, ISSN 1758-5090
Publisher: IOPscience
DOI: 10.1088/1758-5090/ac8cb2

Synthetic mRNA - emerging new class of drug for tissue regeneration

Author(s): Elizabeth Rosado Balmayor
Published in: Current opinion in Biotechnology, Issue Volume 74, April 2022, 2022, Page(s) 8-14, ISSN 0958-1669
Publisher: Elsevier BV
DOI: 10.1016/j.copbio.2021.10.015

Calcium phosphate with submicron topography influences primary human macrophage response, enhancing downstream angiogenesis and osteogenesis in vitro

Author(s): L.A. van Dijk, L. Utomo, H. Yuan, F. Barrère-de Groot, D. Gawlitta, A.J.W.P. Rosenberg, J.D. de Bruijn
Published in: Journal of Immunology and Regenerative Medicine, Issue 19, 2023, Page(s) 100070, ISSN 2468-4988
Publisher: Elsevier
DOI: 10.1016/j.regen.2023.100070

The osteo-angiogenic signaling crosstalk for bone regeneration: harmony out of complexity

Author(s): Nunzia Di Maggio; Andrea Banfi
Published in: Current Opinion in Biotechnology, Issue 2, 2022, ISSN 1879-0429
Publisher: Elsevier London
DOI: 10.1016/j.copbio.2022.102750

Characterization and biological evaluation of 3D printed composite ink consisting of collagen, hyaluronic acid and calcium phosphate for bone regeneration

Author(s): D. Van der Heide, L.P. Hatt, E. Della Bella, A. Hangartner, W.A. Lackington, H. Yuan, F. De Groot-Barrère, M.J. Stoddart, M. D'Este
Published in: Carbohydrate Polymer Technologies and Applications, Issue 7, 2024, Page(s) 100518, ISSN 2666-8939
Publisher: Elsevier
DOI: 10.1016/j.carpta.2024.100518

Cellular uptake of modified mRNA occurs via caveolae-mediated endocytosis, yielding high protein expression in slow-dividing cells

Author(s): Claudia Del Toro Runzer, Shivesh Anand, Carlos Mota, Lorenzo Moroni, Christian Plank, Martijn van Griensven, Elizabeth R. Balmayor
Published in: Molecular Therapy - Nucleic Acids, Issue 32, 2024, Page(s) 960-979, ISSN 2162-2531
Publisher: Nature Publishing Group
DOI: 10.1016/j.omtn.2023.05.019

In vitro osteogenesis of hMSCs on collagen membranes embedded within LEGO<sup>®</sup>-inspired 3D printed PCL constructs for mandibular bone repair

Author(s): Daphne van der Heide, Luan Phelipe Hatt, Sylvie Wirth, Maria E Pirera, Angela R Armiento, Martin J Stoddart
Published in: Biofabrication, Issue 16, 2024, Page(s) 045020, ISSN 1758-5082
Publisher: IOS Press
DOI: 10.1088/1758-5090/ad6931

Robust coupling of angiogenesis and osteogenesis by VEGF-decorated matrices for bone regeneration

Author(s): Maximilian G. Burger, Andrea Grosso, Priscilla S. Briquez, Gordian M.E. Born, Alexander Lunger, Flavio Schrenk, Atanas Todorov, Veronica Sacchi, Jeffrey A. Hubbell, Dirk J. Schaefer, Andrea Banfi, Nunzia Di Maggio
Published in: Acta Biomaterialia, Issue 149, 2024, Page(s) 111-125, ISSN 1742-7061
Publisher: Elsevier BV
DOI: 10.1016/j.actbio.2022.07.014

Fibrin-based factor delivery for therapeutic angiogenesis: friend or foe?

Author(s): Ludovic Melly; Andrea Banfi
Published in: Cell and tissue research, Vol. 387, no. 3, p. 451-460 (2022), Issue 1, 2022, Page(s) p. 451-460, ISSN 1432-0878
Publisher: Berlin, New York, Springer-Verlag
DOI: 10.1007/s00441-022-03598-w

Deliverables

Publications

Share this page

Download