Proteomic analysis of Src family kinase phosphorylation states in cancer cells suggests deregulation of the unique domain
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Author(s):
Ruiz-Saenz A, Zahedi F, Peterson E, Yoo A, Dreyer CA, Spassov DS, Oses-Prieto J, Burlingame A, Moasser MM
Published in:
Mol Cancer Res, Issue 19(6), 2021, Page(s) 957-967, ISSN 1541-7786
Publisher:
American Association for Cancer Research
DOI:
10.1158/1541-7786.mcr-20-0825
A reversible SRC-relayed COX2 inflammatory program drives resistance to BRAF and EGFR inhibition in BRAFV600E colorectal tumors
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Author(s):
Ruiz-Saenz A, Atreya CE, Wang C, Pan B, Dreyer CA, Brunen D, Prahallad A, Muñoz DP, Ramms DJ, Burghi V, Spassov DS, Fewings E, Hwang YC, Cowdrey C, Moelders C, Schwarzer C, Wolf DM, Hann B, VandenBerg SR, Shokat K, Moasser MM, Bernards R, Gutkind JS, van 't Veer LJ, Coppé JP. A
Published in:
Nature Cancer, Issue 4(2), 2023, Page(s) 240–256, ISSN 2662-1347
Publisher:
Nature publishing group
DOI:
10.1038/s43018-022-00508-5
A role of salt bridges in mediating drug potency: A lesson from the N-myristoyltransferase inhibitors
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Author(s):
Spassov DS, Atanasova M, Doytchinova I
Published in:
Front Mol Biosci, Issue 9, 2023, Page(s) 1066029, ISSN 2296-889X
Publisher:
Frontiers
DOI:
10.3389/fmolb.2022.1066029
Novel Hits for N-Myristoyltransferase Inhibition Discovered by Docking-Based Screening
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Author(s):
Spassov DS, Atanasova M, Doytchinova I.
Published in:
Molecules, Issue 27(17), 2022, Page(s) 5478, ISSN 1420-3049
Publisher:
Multidisciplinary Digital Publishing Institute (MDPI)
DOI:
10.3390/molecules27175478
