Novel Symbioses

Project Information

SYMBIOSES

Grant agreement ID: 883077

DOI

10.3030/883077

Project closed

EC signature date 28 April 2020

Start date 1 January 2021

End date 31 December 2025

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 500 000,00

EU contribution

€ 2 500 000,00

Coordinated by

EIDGENOESSISCHE TECHNISCHE HOCHSCHULE ZUERICH
Switzerland

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (9)

Live-seq enables temporal transcriptomic recording of single cells

Author(s): Wanze Chen, Orane Guillaume-Gentil, Pernille Yde Rainer, Christoph G. Gäbelein, Wouter Saelens, Vincent Gardeux, Amanda Klaeger, Riccardo Dainese, Magda Zachara, Tomaso Zambelli, Julia A. Vorholt, Bart Deplancke
Published in: Nature, Issue 608, 2022, Page(s) 733-740, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-022-05046-9

Induced endosymbiosis between a fungus and bacterium reveals a shift from antagonism to commensalism

Author(s): Thomas Gassler, Gabriel H. Giger, Anna Sintsova, Olivia X. Bossert, Alannah Holderbusch, Miriam Bortfeld-Miller, Benoit Dehapiot, Shinichi Sunagawa, Julia A. Vorholt
Published in: Nature Communications, Issue 16, 2025, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-025-65741-9

Inducing novel endosymbioses by implanting bacteria in fungi

Author(s): Gabriel H. Giger, Chantal Ernst, Ingrid Richter, Thomas Gassler, Christopher M. Field, Anna Sintsova, Patrick Kiefer, Christoph G. Gäbelein, Orane Guillaume–Gentil, Kirstin Scherlach, Miriam Bortfeld-Miller, Tomaso Zambelli, Shinichi Sunagawa, Markus Künzler, Christian Hertweck, Julia A. Vorholt
Published in: Nature, Issue 635, 2024, Page(s) 415-422, ISSN 0028-0836
Publisher: Nature Publishing Group
DOI: 10.1038/s41586-024-08010-x

Direct Salmonella injection into enteroid cells allows the study of host–pathogen interactions in the cytosol with high spatiotemporal resolution

Author(s): Chantal Ernst, Patrick R. Andreassen, Gabriel H. Giger, Bidong D. Nguyen, Christoph G. Gäbelein, Orane Guillaume-Gentil, Stefan A. Fattinger, Mikael E. Sellin, Wolf-Dietrich Hardt, Julia A. Vorholt
Published in: PLOS Biology, Issue 22, 2024, Page(s) e3002597, ISSN 1545-7885
Publisher: Public Library of Science (PLoS)
DOI: 10.1371/journal.pbio.3002597

Injection into and extraction from single fungal cells

Author(s): Orane Guillaume-Gentil, Christoph G. Gäbelein, Stefanie Schmieder, Vincent Martinez, Tomaso Zambelli, Markus Künzler, Julia A. Vorholt
Published in: Communications Biology, Issue 5, 2022, Page(s) 180, ISSN 2399-3642
Publisher: Springer Nature
DOI: 10.1038/s42003-022-03127-z

Engineering Endosymbiotic Growth of E. coli in Mammalian Cells

Author(s): Christoph G. Gäbelein; Michael A. Reiter; Chantal Ernst; Gabriel H. Giger; Julia A. Vorholt
Published in: ACS Synthetic Biology, Issue 11, 2022, Page(s) 3388-3396, ISSN 2161-5063
Publisher: American Chemical Society
DOI: 10.3929/ethz-b-000580996

Mitochondria transplantation between living cells

Author(s): Christoph G. Gäbelein; Qian Feng; Edin Sarajlic; Tomaso Zambelli; Orane Guillaume-Gentil; Benoît Kornmann; Julia A. Vorholt
Published in: PLoS Biology, Issue 1, 2022, ISSN 1545-7885
Publisher: PLOS
DOI: 10.1371/journal.pbio.3001576

Fluidic force microscopy

Author(s): Tomaso Zambelli, Orane Guillaume-Gentil, Edin Sarajlic, Georg Papastavrou, Robert Horvath, Gang-yu Liu, Mi Li, Julia A. Vorholt
Published in: Nature Reviews Methods Primers, Issue 6, 2026, ISSN 2662-8449
Publisher: Springer Science and Business Media LLC
DOI: 10.1038/s43586-025-00463-2

NAIP/NLRC4 inflammasome dynamics in murine enteroids are tuned by NAIP ligand concentration and epithelial cell differentiation

Author(s): Patrick Rosendahl Andreassen, Chantal Ernst, Marisa Pimentel Mendes, Thea Bill Andersen, Orane Guillaume-Gentil, Stefan A. Fattinger, Mikael E. Sellin, Wolf-Dietrich Hardt, Julia A. Vorholt
Published in: Cell Reports, Issue 44, 2026, Page(s) 116143, ISSN 2211-1247
Publisher: Cell Press
DOI: 10.1016/j.celrep.2025.116143