Artificial Translation with Dynamic Foldamers: Relaying Encoded Messages into Chemical Function

Project Information

DOGMATRON

Grant agreement ID: 883786

DOI

10.3030/883786

EC signature date 23 April 2020

Start date 1 October 2020

End date 30 September 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost

€ 2 499 805,00

EU contribution

€ 2 499 805,00

Coordinated by

UNIVERSITY OF BRISTOL
United Kingdom

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Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Peer reviewed articles (8)

Dynamic and Persistent Cyclochirality in Hydrogen-Bonded Derivatives of Medium-Ring Triamines

Author(s): David T. J. Morris, Steven M. Wales, Javier Echavarren, Matej Žabka, Giulia Marsico, John W. Ward, Natalie E. Pridmore, Jonathan Clayden
Published in: Journal of the American Chemical Society, Issue 145, 2023, Page(s) 19030-19041, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.3c06570

Inducing a pH-dependent conformational response by competitive binding to Zn2+ of a series of chiral ligands of disparate basicity

Author(s): Matthew M. Wootten; Bryden A. F. Le Bailly; Sofja Tshepelevitsh; Ivo Leito; Jonathan Clayden
Published in: Crossref, Issue 1, 2022, ISSN 2041-6539
Publisher: RSC
DOI: 10.1039/d1sc06812a

Reversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer.

Author(s): Jonathan Clayden; David Morris; Steven Wales
Published in: Wales , S M , Morris , D T J & Clayden , J 2022 , ' Reversible Capture and Release of a Ligand Mediated by a Long-Range Relayed Polarity Switch in a Urea Oligomer ' , Journal of the American Chemical Society , vol. 144 , no. 7 , pp. 2841-2846 . https://doi.org/10.1021/jacs.1c11928, Issue 1, 2022, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.1c11928

Conformational preference in difluoroacetamide oligomers: probing the potential for foldamers with C–H⋯O hydrogen bonds

Author(s): Matej Žabka, Jonathan Clayden
Published in: Organic & Biomolecular Chemistry, Issue 21, 2024, Page(s) 5939-5943, ISSN 1477-0520
Publisher: Royal Society of Chemistry
DOI: 10.1039/d3ob00811h

Switching imidazole reactivity by dynamic control of tautomer state in an allosteric foldamer

Author(s): David P. Tilly, Jean-Paul Heeb, Simon J. Webb, Jonathan Clayden
Published in: Nature Communications, Issue 14, 2024, ISSN 2041-1723
Publisher: Nature Publishing Group
DOI: 10.1038/s41467-023-38339-2

A Chemically Fuelled Molecular Automaton Displaying Programmed Migration of Zn²⁺ Between Alternative Binding Sites

Author(s): Matthew M. Wootten; Sofja Tshepelevitsh; Ivo Leito; Jonathan Clayden
Published in: Chemistry - A European Journal, Issue 1, 2022, ISSN 1521-3765
Publisher: Wiley VCH
DOI: 10.1002/chem.202202247

Supramolecular interactions between ethylene-bridged oligoureas: nanorings and chains formed by cooperative positive allostery.

Author(s): David P. Tilly; Matej Žabka; Inigo Vitorica-Yrezabal; Hazel A. Sparkes; Natalie Pridmore; Jonathan Clayden
Published in: Tilly , D P , Žabka , M , Vitorica-Yrezabal , I , Sparkes , H A , Pridmore , N & Clayden , J 2022 , ' Supramolecular interactions between ethylene-bridged oligoureas : nanorings and chains formed by cooperative positive allostery ' , Chemical Science , vol. 13 , no. 44 , pp. 13153-13159 . https://doi.org/10.1039/d2sc04716k, Issue 1, 2022, ISSN 2041-6539
Publisher: RSC
DOI: 10.1039/d2sc04716k

Benzo‐fused Nitrogen Heterocycles by Asymmetric Ring Expansion and Stereochemically Retentive Re‐contraction of Cyclic Ureas

Author(s): Rajendra K. Mallick, Matej Žabka, Jonathan Clayden
Published in: Angewandte Chemie, Issue 136, 2024, ISSN 0044-8249
Publisher: Wiley
DOI: 10.1002/ange.202318417