Project description
Dissecting the molecular mechanisms underlying radiotherapy resistance
Radiotherapy is a common cancer treatment, but despite its success, it is hampered by the emergence of local resistance and distant metastases. The key objective of the EU-funded TETHER project is to unveil the molecular mechanisms underlying radiotherapy resistance. Researchers will perform gene editing in unique mouse models and organoids to map the functional network of genes that play a significant role in radiotherapy resistance. Delineation of the mechanisms used by cancer cells to escape radiotherapy will provide important insight into the design of personalised approaches to improve treatment response in cancer patients.
Fields of science
Programme(s)
Topic(s)
Funding Scheme
ERC-ADG - Advanced Grant
Host institution
UNIVERSITAET BERN
Net EU contribution
€ 2 499 875,00
Address
Hochschulstrasse 6
3012 Bern
Switzerland
3012 Bern
Switzerland
See on map
Region
Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00
Beneficiaries (1)
UNIVERSITAET BERN
Switzerland
Net EU contribution
€ 2 499 875,00
Address
Hochschulstrasse 6
3012 Bern
3012 Bern
See on map
Region
Schweiz/Suisse/Svizzera Espace Mittelland Bern / Berne
Activity type
Higher or Secondary Education Establishments
Other funding
€ 0,00