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CORDIS

Inhibiting BAF to Improve Gene Delivery

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

The intracellular visualization of exogenous DNA in fluorescence microscopy (opens in new window)

Author(s): Christina Greitens, Jean-Christophe Leroux, Michael Burger
Published in: Drug Delivery and Translational Research, Issue 14, 2024, Page(s) 2242-2261, ISSN 2190-393X
Publisher: Springer Pub. Co.,
DOI: 10.1007/s13346-024-01563-4

Modular Calcium‐Responsive and CD9‐Targeted Phospholipase System Enhancing Endosomal Escape for DNA Delivery (opens in new window)

Author(s): Alexander Klipp, Christina Greitens, David Scherer, Alexander Elsener, Jean‐Christophe Leroux, Michael Burger
Published in: Advanced Science, Issue 12, 2025, ISSN 2198-3844
Publisher: Wiley
DOI: 10.1002/advs.202410815

Activity-Based Approach for Selective Molecular CO 2 Sensing (opens in new window)

Author(s): Ori Green; Patrick Finkelstein; Miguel A. Rivero-Crespo; Marius D. R. Lutz; Michael K. Bogdos; Michael Burger; Jean-Christophe Leroux; Bill Morandi
Published in: Journal of the American Chemical Society, 144 (19), Issue 3, 2022, Page(s) 8717-8724, ISSN 0002-7863
Publisher: American Chemical Society
DOI: 10.1021/jacs.2c02361

Hurdles to healing: Overcoming cellular barriers for viral and nonviral gene therapy (opens in new window)

Author(s): Steffen Honrath, Michael Burger, Jean-Christophe Leroux
Published in: International Journal of Pharmaceutics, Issue 674, 2025, Page(s) 125470, ISSN 0378-5173
Publisher: Elsevier BV
DOI: 10.1016/j.ijpharm.2025.125470

The TFAMoplex-Conversion of the Mitochondrial Transcription Factor A into a DNA Transfection Agent (opens in new window)

Author(s): Burger, Michael; Kaelin, Seraina; Leroux, Jean-Christophe; id_orcid0000-0001-5601-1292
Published in: Advanced Science, 9 (8), Issue 2104987, 2022, ISSN 2198-3844
Publisher: Wiley-VCH
DOI: 10.1002/advs.202104987

Enzymatic absorption promoters for non-invasive peptide delivery (opens in new window)

Author(s): Marilena Bohley Steiger, Angela Steinauer, Daniel Gao, David Klein Cerrejon, Hanna Krupke, Miguel Heussi, Padryk Merkl, Alexander Klipp, Michael Burger, Cristina Martin-Olmos, Jean-Christophe Leroux
Published in: Journal of Controlled Release, Issue 382, 2025, Page(s) 113675, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2025.113675

Get out or die trying: peptide- and protein-based endosomal escape of RNA therapeutics (opens in new window)

Author(s): Klipp, Alexander; Burger, Michael; Leroux, Jean-Christophe
Published in: Advanced Drug Delivery Reviews, 200, Issue 3, 2023, Page(s) 115047, ISSN 1872-8294
Publisher: Elsevier
DOI: 10.3929/ethz-b-000624998

Revival of Bioengineered Proteins as Carriers for Nucleic Acids (opens in new window)

Author(s): David Scherer, Michael Burger, Jean-Christophe Leroux
Published in: Bioconjugate Chemistry, Issue 35, 2024, Page(s) 561-566, ISSN 1043-1802
Publisher: American Chemical Society
DOI: 10.1021/acs.bioconjchem.4c00079

Closing the gap: Nonviral TFAMoplex transfection boosted by bZIP domains compared to AAV-mediated transduction (opens in new window)

Author(s): Steffen Honrath, Miguel Heussi, Lukas Beckert, David Scherer, Roderick Y.H. Lim, Michael Burger, Jean-Christophe Leroux
Published in: Molecular Therapy Nucleic Acids, Issue 36, 2025, Page(s) 102526, ISSN 2162-2531
Publisher: Nature Publishing Group
DOI: 10.1016/j.omtn.2025.102526

Interaction proteomics analysis to provide insight into TFAMoplex-mediated transfection (opens in new window)

Author(s): Steffen Honrath, David Scherer, Michael Burger, Jean-Christophe Leroux
Published in: Journal of Controlled Release, Issue 373, 2024, Page(s) 252-264, ISSN 0168-3659
Publisher: Elsevier BV
DOI: 10.1016/j.jconrel.2024.07.025

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