A PRECISION CELL REPLACEMENT STRATEGY FOR PARKINSON’S DISEASE

Project Information

PreciseCellPD

Grant agreement ID: 884608

DOI 10.3030/884608

EC signature date 27 November 2020

Start date 1 March 2021

End date 28 February 2026

Funded under

• EXCELLENT SCIENCE - European Research Council (ERC)

Total cost € 2 500 000,00

EU contribution € 2 500 000,00

Coordinated by

KAROLINSKA INSTITUTET
Sweden

Publications

Peer reviewed articles (4)

Comprehensive cell atlas of the first-trimester developing human brain.

Author(s): "Emelie Braun, Miri Danan-Gotthold, Lars E. Borm, Elin Vinsland, Ka Wai Lee, Peter Lönnerberg, Lijuan Hu, Xiaofei Li, Xiaoling He, Žaneta Andrusivová, Joakim Lundeberg, Roger A. Barker, Ernest Arenas#, Erik Sundström#, Sten Linnarsson"
Published in: Science, Issue Oct 13;382(6667), 2023, Page(s) eadf1226, ISSN 1872-6291
Publisher: Science
DOI: 10.1126/science.adf1226

A reference induced pluripotent stem cell line for large-scale collaborative studies

Author(s): Caroline B. Pantazis1*, Andrian Yang2-5*, Erika Lara1*, Justin A. McDonough6*, Cornelis Blauwendraat1,7*, Lirong Peng1,8,9*, Hideyuki Oguro6,10, Jitendra Kanaujiya6,10, Jizhong Zou11, David Sebesta12, Gretchen Pratt12, Erin Cross12, Jeffrey Blockwick12, Philip Buxton12, Lauren Kinner-Bibeau12, Constance Medura12, Christopher Tompkins12, Stephen Hughes12, Marianita Santiana1, Faraz Faghri1,7,8, Mik
Published in: Cell Stem Cells, Issue Dec 1;29(12), 2022, Page(s) 1685-1702.e22, ISSN 1934-5909
Publisher: Cell Press
DOI: 10.1016/j.stem.2022.11.004

A protocol for the differentiation of human embryonic stem cells into midbrain dopaminergic neurons

Author(s): Nishimura K, Ásgrímsdóttir ES, Yang S, Arenas E.
Published in: STAR Protocols, Issue Jun 12;4(3):, 2023, Page(s) 102355, ISSN 2666-1667
Publisher: Cell press
DOI: 10.1016/j.xpro.2023.102355

Single cell transcriptomics reveals correct developmental dynamics and high-quality midbrain cell types by improved hESC differentiation.

Author(s): Kaneyasu Nishimura1,2, Shanzheng Yang1*, Ka Wai Lee1*, Emilia Sif Asgrimsdottir1, Kasra Nikodei1, Wojciech Paslawski3, Gnodde Sabine1, Guochang Lyu1, Lijuan Hu1, Carmen Saltó1, Per Svenningsson3, Jens Hjerling-Leffler1, Sten Linnarsson1 and Ernest Arenas1,*
Published in: Stem cell reports, Issue January 10,Vol.18, 2023, Page(s) 227-353, ISSN 2213-6711
Publisher: Cell Press
DOI: 10.1016/j.stemcr.2022.10.016

Other (2)

Parkinson’s disease in the single cell era.

Author(s): Arenas E
Published in: Nature Neuroscience, Issue News and Views, May;25(5), 2022, Page(s) 536-538, ISSN 1546-1726
Publisher: Nature
DOI: 10.1038/s41593-022-01069-7

Transcriptomic diversity of cell types across the adult human brain

Author(s): Kimberly Siletti, Rebecca Hodge, Alejandro Mossi Albiach, Lijuan Hu, Ka Wai Lee, Peter Lönnerberg, Trygve Bakken, Song-Lin Ding, Michael Clark, Tamara Casper, Nick Dee, Jessica Gloe, C. Dirk Keene, Julie Nyhus, Herman Tung, Anna Marie Yanny, Ernest Arenas, Ed S. Lein, Sten Linnarsson
Published in: 2022
Publisher: BioRxiv
DOI: 10.1101/2022.10.12.511898