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Designer enzymes featuring unnatural amino acids as catalytic residue

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Publications

Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel-Crafts Alkylase

Author(s): Reuben B. Leveson-Gower; Zhi Zhou; Ivana Drienovská; Gerard Roelfes
Published in: ACS Catalysis, 3, 2021, Page(s) 6763–6770, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.1c00996

Chemogenetic Tags with Probe Exchange for Live-Cell Fluorescence Microscopy.

Author(s): Aditya Iyer; Maxim Baranov; Alexander J. Foster; Shreyans Chordia; Gerard Roelfes; Rifka Vlijm; Geert van den Bogaart; Bert Poolman
Published in: Acs Chemical Biology, 16, 891 - 904, 5, 2021, Page(s) 891–904, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.1c00100

Repurposed and artificial heme enzymes for cyclopropanation reactions.

Author(s): Gerard Roelfes
Published in: Journal of Inorganic Biochemistry, 222:111523. ELSEVIER SCIENCE INC, 4, 2021, Page(s) 111523, ISSN 0162-0134
Publisher: Elsevier BV
DOI: 10.1016/j.jinorgbio.2021.111523

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme.

Author(s): Zhi Zhou; Gerard Roelfes
Published in: ACS Catalysis, 3, 2021, Page(s) 366–9369, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.1c02298