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Designer enzymes featuring unnatural amino acids as catalytic residue

CORDIS provides links to public deliverables and publications of HORIZON projects.

Links to deliverables and publications from FP7 projects, as well as links to some specific result types such as dataset and software, are dynamically retrieved from OpenAIRE .

Publications

Unlocking Iminium Catalysis in Artificial Enzymes to Create a Friedel-Crafts Alkylase

Author(s): Reuben B. Leveson-Gower; Zhi Zhou; Ivana Drienovská; Gerard Roelfes
Published in: ACS Catalysis, Issue 3, 2021, Page(s) 6763–6770, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.1c00996

Chemogenetic Tags with Probe Exchange for Live-Cell Fluorescence Microscopy.

Author(s): Aditya Iyer; Maxim Baranov; Alexander J. Foster; Shreyans Chordia; Gerard Roelfes; Rifka Vlijm; Geert van den Bogaart; Bert Poolman
Published in: Acs Chemical Biology, 16, 891 - 904, Issue 5, 2021, Page(s) 891–904, ISSN 1554-8929
Publisher: American Chemical Society
DOI: 10.1021/acschembio.1c00100

Biocatalytic Friedel-Crafts Reactions

Author(s): Reuben B. Leveson‐Gower; Gerard Roelfes
Published in: ChemCatChem, Issue 1, 2022, Page(s) e202200636, ISSN 1867-3899
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cctc.202200636

Tandem Friedel-Crafts-Alkylation-Enantioselective-Protonation by Artificial Enzyme Iminium Catalysis

Author(s): Reuben B. Leveson-Gower; Ruben de Boer; Gerard Roelfes
Published in: ChemCatChem, Issue 1, 2022, Page(s) e202101875, ISSN 1867-3899
Publisher: Wiley-VCH GmbH
DOI: 10.1002/cctc.202101875

Repurposed and artificial heme enzymes for cyclopropanation reactions.

Author(s): Gerard Roelfes
Published in: Journal of Inorganic Biochemistry, 222:111523. ELSEVIER SCIENCE INC, Issue 4, 2021, Page(s) 111523, ISSN 0162-0134
Publisher: Elsevier BV
DOI: 10.1016/j.jinorgbio.2021.111523

Synergistic Catalysis of Tandem Michael Addition/Enantioselective Protonation Reactions by an Artificial Enzyme.

Author(s): Zhi Zhou; Gerard Roelfes
Published in: ACS Catalysis, Issue 3, 2021, Page(s) 366–9369, ISSN 2155-5435
Publisher: American Chemical Society
DOI: 10.1021/acscatal.1c02298

An In Vivo Biocatalytic Cascade Featuring an Artificial Enzyme Catalyzed New-to-Nature Reaction

Author(s): Linda Ofori Atta; Zhi Zhou; Gerard Roelfes
Published in: Angewandte Chemie International Edition, Issue 2, 2023, Page(s) e202214191, ISSN 1433-7851
Publisher: John Wiley & Sons Ltd.
DOI: 10.1002/anie.202214191

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